An increasing amount of evidence indicates that there exists a pool of autoantibodies inthe serum of normal animals and humans. Characterized by low affinity andpolyreactivity, they are termed natural autoantibody, or...An increasing amount of evidence indicates that there exists a pool of autoantibodies inthe serum of normal animals and humans. Characterized by low affinity andpolyreactivity, they are termed natural autoantibody, or NAA, to be distinguishable frompathologically occurring autoantibodies. The existence and discovery of NAA render a chal-lenge to the traditionally accepted point of view that autoantibodies are harmful, and im-pose a new subject on modern immunology. The biogenesis and physiological展开更多
基金Project supported by Japan Sasagawa Scholarship for Medicine.
文摘An increasing amount of evidence indicates that there exists a pool of autoantibodies inthe serum of normal animals and humans. Characterized by low affinity andpolyreactivity, they are termed natural autoantibody, or NAA, to be distinguishable frompathologically occurring autoantibodies. The existence and discovery of NAA render a chal-lenge to the traditionally accepted point of view that autoantibodies are harmful, and im-pose a new subject on modern immunology. The biogenesis and physiological
