Study on the Effect of Early Oral Motor Intervention in Preterm Infants in Neonatal Intensive Care Unit

Objective:To study the effective value of introducing the concept of early oral exercise in the process of nursing intervention for preterm infants in the neonatal intensive care unit(NICU).Methods:96 cases of preterm infants diagnosed from January 2022 to August 2022 were selected and randomly divided into two groups:the general practice group(general nursing intervention),and the early practice group(early oral exercise intervention),and the effect of intervention on preterm infants in the two groups was observed.Results:After nursing care,the mean value of the non-nutritive sucking ability assessment(76.54±5.82),the mean value of the intellectual development degree assessment(104.57±8.45),the mean value of the psychomotor development degree assessment(102.33±6.74),and the mean value of behavioral neural reflexes ability assessment(38.71±2.40)in the early practice group were better than that as compared to the general practice group(P<0.05);the mean value of oral feeding start time of preterm infants in the early practice group(35.42±7.63)weeks,the mean value of all oral feeding time(34.12±5.28)weeks,and the mean time of hospital intervention(15.33±4.25)days were lesser than compared to those of the general practice group at 37.4±5.82 weeks,37.46±3.55 weeks,and 20.46±2.91 days,respectively(P<0.05);the rate of adverse reactions in preterm infants in the early practice group significantly lower than that of the general practice group(P<0.05).Conclusion:The introduction of the concept of early oral exercise intervention among NICU nurses improved the feeding effect,sucking ability of preterm infants,and intellectual development.Hence,early oral motor care should be popularized.

The trajectories of physical growth in 4 months postnatal corrected age among preterm infants discharged from neonatal intensive care units and associated factors: A prospective study

Objectives Growth retardation is a risk for premature infants.In addition to demographic and perinatal factors,preterm infants’physical growth may be affected by neonatal intensive care unit(NICU)stress,maternal postpartum depression,and mother-infant interaction.This study aimed to investigate the trajectories of physical growth in 4 months corrected age among preterm infants discharged from the NICU and the impactors on these trajectories.Methods A prospective study was conducted among 318 preterm infants from September 2019 to April 2021 in Shanghai,China.Latent growth modeling was applied to identify the weight,length,and head circumference growth trajectories in 4 months corrected age and explore the effects of demographic and medical characteristics,infant stress during NICU stay,maternal postpartum depression,and mother-infant interaction on each trajectory.Results Unconditional latent growth models showed curve trajectories with increasingly slower growth in weight,length,and head circumference until 4 months of corrected age.Conditional latent growth models showed that a longer length of stay in the NICU and more skin punctures were negatively associated with weight at 40 weeks corrected gestational age(β=−0.43 and−0.19,respectively,P<0.05).The maternal postpartum depression between 40 weeks corrected gestational age and 1 month corrected postnatal age was associated with a lower growth rate of length(β=−0.17,P=0.040),while between 2 and 3 months corrected postnatal age,there were lower growth rates of weight and head circumference(β=−0.15 and−0.19,respectively,P<0.05).The mother-infant interaction scores between 40 weeks corrected gestational age and 1 month corrected postnatal age negatively predicted the growth rate of weight(β=−0.19,P=0.020).Conclusion The physical growth trajectories of preterm infants discharged from the NICU were influenced by infant stress during the NICU stay,maternal postpartum depression and mother-infant interaction.

The Incidence of Respiratory Distress Syndrome among Preterm Infants Admitted to Neonatal Intensive Care Unit: A Retrospective Study

Background: Respiratory distress syndrome (RDS) or hyaline membrane disease (HMD) is the most common cause of neonatal morbidity and mortality in preterm infants. We aimed to determine the frequency of RDS among 3 groups of preterm infants and the value of some related factors. Methods: A cross-sectional, descriptive analytical investigation was carried out in the NICU ward of Akbarabadi Hospital (Tehran-Iran) during spring 2011. Newborns’ data were collected and assessed by using their hospital medical records. Seventy-three preterm infants with gestational age < 34 weeks were hospitalized in the NICU. All participants were divided into 3 groups: extremely preterm (<28 weeks), very preterm (28 to <32 weeks) and moderate preterm (32 to 34 weeks). Frequency of RDS and some related factors were compared among 3 groups. Results: RDS was observed in 65.6% of all participants;however frequency of RDS was not different between three groups. An inversely correlation was found between gestational age and mortality rate (p = 0.05). In regard to Betamethasone administration prior to birth, this interval was significantly longer in alive neonates in comparison to infants who died (p < 0.05). Conclusion: RDS was frequent in preterm neonates with gestational age < 32 weeks. Time of Betamethasone administration prior to birth can significantly influence on neonatal mortality rate.

Mothers’ Knowledge of Health Caring for Premature Infants after Discharge from Neonatal Intensive Care Units in the Gaza Strip, Palestine

Background: Preterm labor is one of the most public health problems related to neonates admitted to Neonatal Intensive Care Unit (NICU). Poor knowledge among mothers about the care requirements of a preterm neonate is immediate cause for post-discharge medical problems in premature and neonates readmission to NICU. Hence, this study aims to evaluate mothers’ knowledge of caring for premature infants post-discharge from Neonatal Intensive Care Units in the Gaza strip. Methods: A Quantitative-based cross-sectional designs study was used to survey 120 mothers of preterm neonates at the time of preterm neonates discharge by face-to-face interview at Al-Shifa medical complex and Nasser hospital between February and June 2018. Results: The results showed that only about 58.4% of mothers of premature babies had good knowledge about health care needed for premature infants after discharge from NICU. Furthermore, there was no statistically significant difference between the level of knowledge and mother’s sociodemographic characteristics (P-values > 0.05). Conclusion: Mothers’ knowledge of premature infants care was not at the optimal level, which might put the newborns at risk. Therefore, the study emphasizes the necessity of thoughtful exchange of health information between team members and mothers and establishing pre- and post-discharge plans with mothers to start their healthy transition of preterm neonate to home and to ameliorate family concerns.

Prevalence and Spectrum of Complex Congenital Heart Disease in the Neonatal Intensive Care Unit at High Altitude in China

Background:Previous studies from high altitudes have reported significantly higher prevalence of congenital heart disease(CHD),consisting almost solely of simple CHD.Little is known about the occurrence of complex CHD.Neonates with complex CHD are likely admitted to NICU.We examined the prevalence and spectrum of complex CHD in NICU in order to depict a truer picture of CHD at high altitude.Methods:We reviewed charts of 4,214 neonates admitted to NICU in Qinghai province(average altitude 3,000 m).Echocardiography was performed in 1,943 babies when CHD was suspected based on clinical examinations.Results:CHD was diagnosed in 1,093(56.3%of echoed babies).Mild CHD in 96.8%(1058 babies).Moderate CHD in 0.8%(9)included 1(0.1%)large secundum atrial septal defect,3(0.3%)moderate pulmonary stenosis,2(0.2%)aortic stenosis and 3(0.3%)partial anomalous pulmonary venous connection.Severe CHD in 2.4%(26)included 6(0.5%)complete atrioventricular septal defect,5(0.5%)complete transposition of the great arteries,5(0.5%)hypoplastic right heart,3(0.3%)hypoplastic left heart,3(0.3%)double outlet right ventricle,3(0.3%)tetralogy of Fallot,2(0.2%)truncus arteriosus,2(0.2%)total anomalous pulmonary venous connection,2(0.2%)severe aortic stenosis,2(0.2%)interrupted aortic arch and 2(0.2%)severe pulmonary stenosis and 1(0.1%)single-ventricle abnormality.At two-years follow-up in 737(67.4%)patients,18(90%)with severe CHD and 38(5.3%)with mild and moderate CHD died,and 15 underwent cardiac surgery with 1 early death.Conclusions:At high altitude,a wide spectrum of CHD exists,with many heretofore unreported complex CHD.There is urgent need for routine echocardiography and early interventions in newborns particularly in NICU.

Liquid Chromatography-tandem Mass Spectrometry for Analysis of Acylcarnitines in Dried Blood Specimens Collected at Autopsy from Neonatal Intensive Care Unit

Objective To investigate the feasibility of analyzing acylcarnitine in dry filter-paper blood spots by liquid chromatography-tandem mass spectrometry(LC-MS/MS) which could be applied to detect inborn errors of metabolism in neonates.Methods We obtained filter-paper blood from 26 dead infants from a neonatal intensive care unit(NICU) between October 1,2008 and September 30,2009.Acylcarnitine and amino acid profiles were obtained with LC-MS/MS.Four infants underwent routine autopsy.The postmortem blood specimens were compared with newborn blood specimens,and with specimens obtained from older infants with metabolic disorders.Results Of all the 26 patients,5(19.2%) were diagnosed as having different kinds of diseases:3 with methylmalonic acidemia(the concentration of C3,and the ratio of C3/C16,C3/C2 increased),1 with maple syrup urine disease(the concentration of leucine and isoleucine increased),and 1 with isovaleric aci-demia(the concentration of C5 increased).Conclusions Postmortem metabolic test can explain infant deaths and provide estimates of deaths attributable to inborn errors of metabolism in NICU.LC-MS/MS is suitable for analysis of postmortem specimens and can be considered for routine application in NICU autopsy.

Healthcare Associated Infection in the Neonatal Intensive Care Unit of King Abdl Aziz Specialist Hospital, Taif, KSA

Healthcare-associated infection is a common problem of newborn in neonatal intensive care units. It results in high mortality rate and serious complications. The Aim: to assess the incidence, etiology and the mortality of healthcareassociated infections of patients in neonatal intensive care unit at King Abdl Aziz Specialist Hospital (KAASH), Taif, Kingdom of Saudi Arabia. Material and Methods: This is a retrospective study including 8033 neonates admitted to neonatal intensive care unit during period between April, 2006 and December, 2012. The health-care associated infection rate, mortality rate, causative organism and risk factors were studied. Results: The prevalence of health-care associated infection was found to be 6.03%;the mortality rate was 27.1%. The highest prevalence was among children with the birth weight below 1000 g. The most frequent causative pathogen was klebseilla spp, followed by other gram negative bacilli. Conclusion: The rate of healthcare-associated infections in neonatal intensive care unit at KAASH was relatively high. In addition, the mortality rate was observed to be high (27.1%) owing to the high virulence of the causative organisms.

Effects of parental involvement in infant care in neonatal intensive care units:a meta-analysis

Objective： This meta-analysis aimed to examine the effects of parental involvement in infant care in neonatal intensive care units （NlCUs）. Methods： PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure （CNKI）, Wanfang database, and VIP database were searched till November 2017. Randomized controlled trials （RCTs） and controlled clinical trials （CCTs） examining the effect of parental involvement in the NICU were considered for inclusion. Resulls： We included 10 studies （three RCTs, seven CCTs） with a total of 1,851 participants. The meta-analysis demonstrated that there were no statistically significant differences on nosocomial infection between two groups （risk ratio [RR] = 0.90, 95% CI 0.63-1.30, P = 0.58）. Compared with no parental involvement groups, parental involvement groups showed more weight gain （mean difference [MD] = 1.47, 95% CI 0.65-2.29, P 〈 0.05）, higher breast-feeding rate （RR = 1.38, 95% CI 1.25-1.53, P 〈 0.05）, lower readmission rate （RR = 0.35, 95% CI 0.15-0.80, P 〈 0.05）, and higher satisfaction rate （RR = 1.09, 95% CI 1.02-1.16, P 〈 0.05）.Conclusions： Parentaiinvolvement in the NICU interventions could not increase the rate of nosocomial infection of neonates, but could improve their weight gain, breast-feeding and parental satisfaction and decrease their readmission. However, since the conclusion of this meta-analysis was drawn based on the limited number of high-quality RCTs, more hioh-quality studies should be conducted in the future to confirm its positive intervention effects.

Mothers’experiences of neonatal intensive care:A systematic review and implications for clinical practice

BACKGROUND Preterm birth is on the rise worldwide.Neonatal intensive care units(NICUs)have enabled many critically ill newborns to survive.When a premature baby is admitted to the NICU,the mother–infant relationship may be interrupted,affecting the mother's mental health.AIM To examine the maternal emotions associated with having a child in the NICU and provide suggestions for clinical practice.METHODS MEDLINE,CINAHL,PsychARTICLES,and PsychINFO were searched for relevant articles between 2005 to 2019,and six qualitative articles were chosen that explored the experiences of mothers who had a preterm infant in the NICU.The thematic analysis method was used to identify the most common themes.RESULTS Four main themes of the experience of mothers who had a preterm infant in the NICU were identified:Negative emotional impacts on the mother,support,barriers to parenting,and establishment of a loving relationship.CONCLUSION NICU environment is not conducive to mother-child bonding,but we stipulate steps that health care professionals can take to reduce the negative emotional toll on mothers of NICU babies.

Optimization of Exposure Conditions for Computed Radiology Exams in Neonatal Intensive Care

This paper performs a review of existing literature about neonatal imaging in intensive care;we notice that the multiplicity of approaches results in different and sometimes conflicting solutions to optimize acquisition technique of X-ray images. European Guidelines still refer to screen-film combinations used in past decades, current usage of digital technology requires an additional effort to reduce dose to infants and to optimize the sensor’s response exploiting their properties. In this work we investigate response changes of digital medium (computed radiography plates), due to alterations of the beam through incubators components. All combinations in use in our Hospital were tested for evaluating dosimetry and image quality and new exposure solutions were devised to optimize radiology exams, taking into account solutions suggested by the equipments makers. Dose measured was compared with dose levels suggested by European Guidelines, evaluating radiation-induced risk too. Image quality was evaluated in a double-blind comparison by radiologists. An easily repeatable optimization procedure is proposed intended to reduce delivered dose well below European guidelines. The proposed study allowed us to instruct the technologists on the most appropriate methodology for performing the radiology exam, by standardizing the approach to Neonatal Intensive Care Units. We have demonstrated also to radiologic technologists reluctant to use the X-ray tray, as it may optimize imaging in the incubator. We were also able to reduce dose—and radiation-induced risk too—of 37% - 67% depending on the previously used operating mode.

NICU早产儿母乳喂养链式管理效果评价

目的观察链式管理对NICU早产儿母乳喂养及喂养并发症的影响。方法将180例NICU早产儿按入院时间分为对照组和试验组各90例。对照组实施常规NICU母乳喂养策略,试验组在对照组基础上进行链式管理,构建并实施产房、产科和NICU间横向管理和各科室内部纵向管理。结果最终对照组82例、试验组81例早产儿完成研究。干预后,试验组纯母乳喂养率显著高于对照组,试验组早产儿喂养不耐受、坏死性小肠结肠炎、宫外发育迟缓和新生儿高胆红素血症发生率显著低于对照组(均P<0.05),试验组恢复至出生体质量日龄显著短于对照组,出院体质量显著大于对照组(均P<0.05)。结论链式管理有利于提高NICU早产儿的纯母乳喂养率,降低喂养并发症发生率,促进新生儿生长发育。

汉化版Neonatal/Infant Braden Q Scale在NICU新生儿压力性损伤风险评估中的应用

目的:引进翻译美国Neonatal/Infant Braden Q Scale(N/I Braden Q量表)并检验量表信效度。方法:根据Brislin翻译模型对N/I Braden Q量表进行翻译、回译,通过专家咨询对量表进行文化调适。再将量表应用于浙江省某三级甲等医院NICU住院新生儿进行皮肤评估,检验中文版N/I Braden Q量表的信效度。结果:中文版N/I Braden Q量表的评定者间信度系数ICC为0.908(P<0.001);量表的全体一致性S-CVI为0.75,均值S-CVI为0.9583,各条目的内容效度指数为0.83~1;量表的预测临界值为20分,其灵敏度、特异度、阳性预测值、阴性预测值、约登指数分别为75.00%、74.16%、28.13%、95.62%、0.4916,ROC曲线下面积是0.815(95%CI:0.684~0.945)(P<0.001)。结论:中文版N/I Braden Q量表具有良好的信效度,对新生儿压力性损伤发生有早期预警作用,可作为临床护士对患儿进行皮肤评估的结构化指导工具。

Use of antenatal corticosteroids among infants with gestational age at 24 to 31 weeks in 57 neonatal intensive care units of China: a cross-sectional study

Background:Antenatal corticosteroids(ACS)can significantly improve the outcomes of preterm infants.This study aimed to describe the ACS use rates among preterm infants admitted to Chinese neonatal intensive care units(NICU)and to explore perinatal factors associated with ACS use,using the largest contemporary cohort of very preterm infants in China.Methods:This cross-sectional study enrolled all infants born at 24^(+0)to 31^(+6)weeks and admitted to 57 NICUs of the Chinese Neonatal Network from January 1st,2019 to December 30th,2019.The ACS administration was defined as at least one dose of dexamethasone and betamethasone given before delivery.Multiple logistic regressions were applied to determine the association between perinatal factors and ACS usage.Results:A total of 7828 infants were enrolled,among which 6103(78.0%)infants received ACS.ACS use rates increased with increasing gestational age(GA),from 177/259(68.3%)at 24 to 25 weeks’gestation to 3120/3960(78.8%)at 30 to 31 weeks’gestation.Among infants exposed to ACS,2999 of 6103(49.1%)infants received a single complete course,and 33.4%(2039/6103)infants received a partial course.ACS use rates varied from 30.2%to 100%among different hospitals.Multivariate regression showed that increasing GA,born in hospital(inborn),increasing maternal age,maternal hypertension and premature rupture of membranes were associated with higher likelihood to receive ACS.Conclusions:The use rate of ACS remained low for infants at 24 to 31 weeks’gestation admitted to Chinese NICUs,with fewer infants receiving a complete course.The use rates varied significantly among different hospitals.Efforts are urgently needed to propose improvement measures and thus improve the usage of ACS.

NICU早产儿给予母亲心音联合语音刺激优化体格发育的临床实践

目的探讨新生儿重症监护室(NICU)早产儿给予母亲心音联合语音刺激对其体格发育的影响。方法选取2021年1月至2022年6月于南京医科大学附属儿童医院NICU接受治疗的86例早产儿为研究对象,按随机数字表法分2组,每组43例。对照组采用常规护理干预,观察组在对照组基础上给予母亲心音联合语音刺激进行干预,比较2组的体格发育情况、进奶量和家长的护理满意度。结果观察组出生后第5、10天的头围分别为(32.76±1.57)cm、(33.78±1.68)cm,对照组分别为(31.89±1.53)cm、(32.71±1.71)cm,观察组出生后第5、10天的头围大于对照组(P<0.05)。观察组出生后第5、10天的身长分别为(45.98±2.71)cm、(46.83±2.77)cm,对照组分别为(44.71±2.51)cm、(45.45±2.63)cm,观察组出生后第5、10天的身长长于对照组(P<0.05)。观察组出生后第5、10天的体重分别为(2109.59±136.81)g、(2389.71±146.71)g,对照组分别为(2002.63±132.27)g、(2215.59±143.28)g,观察组出生后第5、10天的体重重于对照组(P<0.05)。观察组出生后第5、10天的进奶量分别为(181.15±38.67)mL、(371.76±55.97)mL,对照组分别为(141.26±32.66)mL、(313.57±46.24)mL,观察组出生后第5、10天的进奶量多于对照组(P<0.05)。观察组的家长护理满意度为95.35%,高于对照组的74.42%(P<0.05)。结论NICU早产儿给予母亲心音联合语音刺激进行干预,能优化早产儿的体格发育,增加住院期间的进奶量,提高家长的护理满意度。

基于peplau人际关系理论的模块教学法在NICU护理实习带教中的应用

目的:观察基于peplau人际关系理论的模块教学法在NICU护理实习带教中的应用效果。方法:随机将湖南省郴州市第一人民医院60名护理实习生分为两组,30名护生进入对照组应用传统教学法进行带教,30名护生进入试验组应用基于Peplau人际关系理论的模块教学法进行教学。两组护生的带教时间均为1个月,带教结束后进行出科考试、护生的职业认同感,教学满意度测评。护生的一般资料和评价指标数据均使用SPSS 26.0进行统计学检验,根据检验结果进行组间差异分析和讨论。结果:试验组的操作与理论成绩、职业认同感、教学满意度测评均优于对照组(P<0.05)。结论:基于peplau人际关系理论的模块教学法对提高NICU护理实习生理论与操作成绩具有显著成效,同时可提高职业认同感、护生对临床护理教学的满意度。

声音对NICU早产儿生长发育影响的系统评价再评价

目的检索并再评价声音对NICU早产儿生长发育影响的系统评价,为临床医务人员临床决策及早产儿健康干预策略的持续改进提供参考。方法计算机检索The Cochrane Library、Embase、PubMed、Web of Science、万方、中国知网、维普和中国生物医学文献数据库,检索关于声音对NICU早产儿影响的系统评价/Meta分析/荟萃分析,检索时间为建库至2023年5月。2名研究人员应用AMSTAR对文献进行方法学质量评价后,通过GRADE进行证据整理与分级。结果初检文献405篇,最终纳入文献20篇,AMSTAR质量评价结果表明,高等质量文献有5篇,其余15篇均为中等质量,纳入文献的总体方法学质量较低。采用GRADE系统对20篇系统评价的79条结局指标的证据质量评价结果显示,12条证据为中等质量,34条证据为低等质量,33条证据为极低质量。结论声音干预有利于改善NICU早产儿的相关生理指标、睡眠效率、行为状态、神经行为及大脑发育,可促进早产儿健康恢复,但系统评价的方法学质量和证据的质量均较低,临床实践需谨慎采纳有关证据,并逐步进行更加规范、严谨的研究。

NICU早产儿父母居家照护体验与需求质性研究的Meta整合

目的 整合新生儿重症监护室(NICU)早产儿父母居家照护体验与需求的质性研究,为更好地开展护理实践提供依据。方法 系统检索The Cochrane Library、PubMed、Web of Science、CINAHL、Embase、Scopus、中国知网、万方数据库、中国生物医学文献数据库、维普数据库。搜索关于NICU早产儿出院后父母真实体验与需求的研究文献,检索时限从建库至2023年2月18日。本研究使用JBI循证卫生保健中心质性研究质量评价标准对纳入文献进行质量评价,并进行meta整合。结果 共纳入11篇研究,质量等级均为B级。提炼出52个研究结果,将相似结果归纳组合形成7个新的类别,并整合为3个结果:(1)早产儿出院后父母积极与消极感并存。(2)早产儿父母居家照护过程中感知到的挑战与困难。(3)早产儿父母希望得到足够的社会支持。结论 出院后早产儿父母居家照护水平有待提升,医院及社区需加强联系与合作,针对早产儿出院制定详细且有针对性的宣教措施,并考虑不同地区的卫生保健环境,实施有针对性的理论及技能培训,以确保早产儿出院后能得到积极有效照护。

PDCA循环在提高NICU医护人员手卫生正确率中的应用

目的探讨持续质量改进在新生儿重症监护病房(neonatal intensive care unit,NICU)医护人员手卫生管理中的应用效果,以提高手卫生正确率。方法2022年12月—2023年11月应用PDCA循环管理方法对39名医护人员手卫生的正确性进行持续质量改进,通过制订计划、对策实施、检查与处理4个阶段,及时发现管理中的薄弱环节,不断总结持续改进。对实施质量改进措施前后的手卫生正确率情况进行统计学分析。结果PDCA循环实施后,医护人员手卫生正确率从49.79%提高到95.15%,干预前后手卫生正确率比较,差异有统计学意义(P<0.01);同时正确率在不同指征层面上较实施前均有明显提高。结论应用PDCA循环进行持续质量改进,可以切实有效提高医务人员手卫生正确率。

早产儿NICU住院期间主要照顾者应对方式现状及其相关影响因素分析

目的 分析早产儿NICU住院期间主要照顾者应对方式现状及其相关影响因素。方法 选取2021年10月至2023年1月期间医院NICU收治的早产儿主要照顾者73例作为本次研究调查对象,采用简易应对方式量表(SCSQ)评估主要照顾者应对方式现状,根据照顾者应对方式分为积极应对组,消极应对组,并比较两组基本资料,找出影响照顾者应对方式的相关因素。结果 73例早产儿主要照顾者积极应对57例(78.08%),消极应对16例(21.92%);两组家庭人均月收入、社会支持、SAS评分、PPUS评分比较差异有统计学意义(P<0.05);经多项logistic回归分析结果显示,家庭人均月收入低、社会支持低、焦虑严重、疾病不确定感高是影响早产儿NICU住院期间主要照顾者应对方式的危险因素(OR>1,P<0.05)。结论 早产儿NICU住院期间主要照顾者多积极应对,但仍有部分患者消极应对,受到家庭人均月收入低、社会支持低、焦虑严重、疾病不确定感等危险因素的影响。

基于IPAT的体位管理联合发展性照顾在NICU极/超低出生体重儿中的应用

目的:探讨基于婴儿体位评估工具(IPAT)的体位管理联合发展性照顾在新生儿重症监护室(NICU)极/超低出生体重儿(E/VLBW)中的应用效果。方法:选择2022年1月1日~2023年6月30日NICU收治的120例E/VLBW,按照随机数字表法分为对照组和研究组各60例,对照组采用常规护理干预,研究组在对照组基础上实施基于IPAT的体位管理联合发展性照顾;比较两组干预前后营养状态[包括总蛋白(TP)、白蛋白(ALB)、前白蛋白(PA)]、神经发育情况[采用新生儿20项行为神经测定(NABA)],出生时和干预后体格发育情况(包括头围、体重、身长),康复指标(包括呼吸机使用时间、胃管拔除时间、全肠内营养时间、日睡眠时间、NICU住院时间)和并发症发生情况。结果:干预后,两组TP、ALB、PA水平均高于干预前(P<0.05),且研究组高于对照组(P<0.01);干预后,两组体重、身长、头围均高于出生时(P<0.05),且研究组高于对照组(P<0.01);干预后,两组NABA各维度评分均高于干预前(P<0.05),且研究组高于对照组(P<0.01);研究组呼吸机使用、胃管拔除、全肠内营养、日睡眠和NICU住院时间均短于对照组(P<0.01),并发症发生率低于对照组(P<0.05)。结论:基于IPAT的体位管理联合发展性照顾对NICU中E/VLBW的护理效果显著,能有效改善营养状态,提高体格发育情况和行为能力,缩短康复时间,减少并发症的发生。