OBJECTIVE： To explore the characteristics of prima- ry liver cancer in terms of Traditional Chinese Medi-cine （TCM） by analyzing the variations of the patterns along with the clinical stages. METHODS： The patients...OBJECTIVE： To explore the characteristics of prima- ry liver cancer in terms of Traditional Chinese Medi-cine （TCM） by analyzing the variations of the patterns along with the clinical stages. METHODS： The patients who were hospitalized in the Changhai Hospital of Traditional Chinese Medi- cine dated from March 1999 to December 2008 were included in this retrospective study. The patients were grouped according to their cancer stag- es, and their patterns were judged and quantified according to the ＂Standard diagnosis and quantitative criteria of the common patterns in primary liv-er cancer＂ formulated by the Changhai Hospital of Traditional Chinese Medicine. Statistics methods included ANOVA and nonparametric test, among others.RESULTS： The data of the 398 newly diagnosed patients showed that Qi Stagnation, Blood Stasis, and Dampness patterns were more frequent than the other basic patterns with relatively high scores; patterns of Liver Qi Stagnation, Liver Blood Stasis, and Dampness Heat were more than the other complex patterns and scored relatively high. Scores of Dampness and Liver Qi Stagnation patterns varied among the groups at different stages and the differences were statistically significant （PDampeness= 0.002, PLiver Qi Stagnation ： 0.020）. The highest scores of Damp- ness pattern and Liver Qi Stagnation pattern corresponded with Stage Ⅲ b, and Stage Ⅲ a, respectively. Dampness pattern frequency was higher （P = 0.001） in the Stage Ⅲb group than in other groups.CONCLUSION： Pattern characteristics in patients with primary liver cancer of different clinical stages might manifest in the variations of the Dampness pattern along the process of the disease and the major pathogenic factor of primary liver cancer might be Dampness.展开更多
基金Supported by National Science and Technology Support Program(Application Demonstration of Traditional Chinese Medicine Health Care Service in Prevention and Control of Chronic Non-Infection Disease,No.2012BAI41B05)Shanghai Science and Technology Research Grant Program(Effects of Integrating Therapy of Chinese and Western Medicine on Cancer-Related Fatigue in Primary Liver Cancer Patients,No.12401907600)Shanghai Health Bureau Medical Research Fund Grant Program(Pattern Characteristics and Pathogenesis Evolution in Patients With Hepatitis B.No.2010L048A)
文摘OBJECTIVE： To explore the characteristics of prima- ry liver cancer in terms of Traditional Chinese Medi-cine （TCM） by analyzing the variations of the patterns along with the clinical stages. METHODS： The patients who were hospitalized in the Changhai Hospital of Traditional Chinese Medi- cine dated from March 1999 to December 2008 were included in this retrospective study. The patients were grouped according to their cancer stag- es, and their patterns were judged and quantified according to the ＂Standard diagnosis and quantitative criteria of the common patterns in primary liv-er cancer＂ formulated by the Changhai Hospital of Traditional Chinese Medicine. Statistics methods included ANOVA and nonparametric test, among others.RESULTS： The data of the 398 newly diagnosed patients showed that Qi Stagnation, Blood Stasis, and Dampness patterns were more frequent than the other basic patterns with relatively high scores; patterns of Liver Qi Stagnation, Liver Blood Stasis, and Dampness Heat were more than the other complex patterns and scored relatively high. Scores of Dampness and Liver Qi Stagnation patterns varied among the groups at different stages and the differences were statistically significant （PDampeness= 0.002, PLiver Qi Stagnation ： 0.020）. The highest scores of Damp- ness pattern and Liver Qi Stagnation pattern corresponded with Stage Ⅲ b, and Stage Ⅲ a, respectively. Dampness pattern frequency was higher （P = 0.001） in the Stage Ⅲb group than in other groups.CONCLUSION： Pattern characteristics in patients with primary liver cancer of different clinical stages might manifest in the variations of the Dampness pattern along the process of the disease and the major pathogenic factor of primary liver cancer might be Dampness.
