By means of cervical nerve root stimulation(CRS) method, the amplitudes and latencies of compound motor action potential(CMAP) of brachial biceps and brachial triceps muscles in 41 patients with clinical symptoms and ...By means of cervical nerve root stimulation(CRS) method, the amplitudes and latencies of compound motor action potential(CMAP) of brachial biceps and brachial triceps muscles in 41 patients with clinical symptoms and signs of cervical radiculopathy were observed. The amplitudes of CMAPs on the affected side in the patients were obviously lower than on the healthy side and control group, latencies of CMAPs on the affected side were also significantly prolonged. The results showed that CRS was a sensitive method for making a direct determination of proximal nerve roit cinductiin function, and a good aid for diagnosing cervical radiculopathy.展开更多
Most studies on peripheral nerve injury have focused on repair at the site of injury, but very few have examined the effects of repair strategies on the more proximal neuronal cell bodies. In this study, an approximat...Most studies on peripheral nerve injury have focused on repair at the site of injury, but very few have examined the effects of repair strategies on the more proximal neuronal cell bodies. In this study, an approximately 10-mm-long nerve segment from the ischial tuberosity in the rat was transected and its proximal and distal ends were inverted and sutured. The spinal cord was subjected to pulsed electrical stimulation at T10 and L3, at a current of 6.5 m A and a stimulation frequency of 15 Hz, 15 minutes per session, twice a day for 56 days. After pulsed electrical stimulation, the number of neurons in the dorsal root ganglion and anterior horn was increased in rats with sciatic nerve injury. The number of myelinated nerve fibers was increased in the sciatic nerve. The ultrastructure of neurons in the dorsal root ganglion and spinal cord was noticeably improved. Conduction velocity of the sciatic nerve was also increased. These results show that pulsed electrical stimulation protects sensory neurons in the dorsal root ganglia as well as motor neurons in the anterior horn of the spinal cord after peripheral nerve injury, and that it promotes the regeneration of peripheral nerve fibers.展开更多
For diagnosiug lumbosacral radicuiopathy precisely, electromyogram(EMG),nerve conduction velocity(NCV),conventional H reflex and H reflex by nerve root stimulation were done in 79 patients with clinical symptoms and s...For diagnosiug lumbosacral radicuiopathy precisely, electromyogram(EMG),nerve conduction velocity(NCV),conventional H reflex and H reflex by nerve root stimulation were done in 79 patients with clinical symptoms and signs of lumbosacral radiculopathy.The rate or appearance fibrillation voltage and/or positive sharp wave in the paraspinal muscles was the highest among them.In the comparison of the affected and the healthy sides in patients with S1 radlculopathy,and of affected side and control group,H-M wave interval of H reflex by nerve root stimulation were significantly prolonged(P<0.01,P<0.05);compared with control group,the dirference or H-M wave interval between the two sides was also significantly prolonged (P<0. 05).But the differences were not so significant in patients with L5 radlculopathy.The results suggest that the abnormal changes or EMG or the paraspinal muscles and H reflex by nerve root stimulation are reliable methods of diagnosing lumbosacral radiculopathy, H reflex by nerve root stimulation can be used to differentiate L5 and S1 nerve root lesions,and measure motor conduction velocity(MCV)and sensory conduction velocity(SCV) or the proximal sciatic nerve.展开更多
文摘By means of cervical nerve root stimulation(CRS) method, the amplitudes and latencies of compound motor action potential(CMAP) of brachial biceps and brachial triceps muscles in 41 patients with clinical symptoms and signs of cervical radiculopathy were observed. The amplitudes of CMAPs on the affected side in the patients were obviously lower than on the healthy side and control group, latencies of CMAPs on the affected side were also significantly prolonged. The results showed that CRS was a sensitive method for making a direct determination of proximal nerve roit cinductiin function, and a good aid for diagnosing cervical radiculopathy.
基金supported by the Key Scientific and Technological Program of Linyi City of China,No.201313026
文摘Most studies on peripheral nerve injury have focused on repair at the site of injury, but very few have examined the effects of repair strategies on the more proximal neuronal cell bodies. In this study, an approximately 10-mm-long nerve segment from the ischial tuberosity in the rat was transected and its proximal and distal ends were inverted and sutured. The spinal cord was subjected to pulsed electrical stimulation at T10 and L3, at a current of 6.5 m A and a stimulation frequency of 15 Hz, 15 minutes per session, twice a day for 56 days. After pulsed electrical stimulation, the number of neurons in the dorsal root ganglion and anterior horn was increased in rats with sciatic nerve injury. The number of myelinated nerve fibers was increased in the sciatic nerve. The ultrastructure of neurons in the dorsal root ganglion and spinal cord was noticeably improved. Conduction velocity of the sciatic nerve was also increased. These results show that pulsed electrical stimulation protects sensory neurons in the dorsal root ganglia as well as motor neurons in the anterior horn of the spinal cord after peripheral nerve injury, and that it promotes the regeneration of peripheral nerve fibers.
文摘For diagnosiug lumbosacral radicuiopathy precisely, electromyogram(EMG),nerve conduction velocity(NCV),conventional H reflex and H reflex by nerve root stimulation were done in 79 patients with clinical symptoms and signs of lumbosacral radiculopathy.The rate or appearance fibrillation voltage and/or positive sharp wave in the paraspinal muscles was the highest among them.In the comparison of the affected and the healthy sides in patients with S1 radlculopathy,and of affected side and control group,H-M wave interval of H reflex by nerve root stimulation were significantly prolonged(P<0.01,P<0.05);compared with control group,the dirference or H-M wave interval between the two sides was also significantly prolonged (P<0. 05).But the differences were not so significant in patients with L5 radlculopathy.The results suggest that the abnormal changes or EMG or the paraspinal muscles and H reflex by nerve root stimulation are reliable methods of diagnosing lumbosacral radiculopathy, H reflex by nerve root stimulation can be used to differentiate L5 and S1 nerve root lesions,and measure motor conduction velocity(MCV)and sensory conduction velocity(SCV) or the proximal sciatic nerve.
