Digital circuit and analog circuit courses are basic courses for students of science and engineering universities. Among them,the practical courses are of great significance for students to master the knowledge of ele...Digital circuit and analog circuit courses are basic courses for students of science and engineering universities. Among them,the practical courses are of great significance for students to master the knowledge of electronics. In order to make teachers teaching more efficiently and students studying more quickly,how to update the experimental course in teaching reform is the key point. This paper analyzing the present situation of teaching in the digital circuit and analog circuit courses,the teaching questions in universities. On the basis of it,the innovation measures of experimental teaching methods and contents are discussed. Our school tries to introduce the UltraLab network experiment platform,reform and optimize the teaching methods of related courses.And it’ s accelerating the construction and development of emerging engineering education’ s process,reducing effectively the teacher’s time for managing in equipment,improving the students’ ability to use instruments.展开更多
The electrical energy produced must be consumed at the same time, hence the need to achieve a balance between supply and demand. Therefore, the production, transport, and distribution systems together constitute an el...The electrical energy produced must be consumed at the same time, hence the need to achieve a balance between supply and demand. Therefore, the production, transport, and distribution systems together constitute an electricity network. The distribution networks are designed to deliver energy to consumers. Unacceptable voltage drops are observed in the distribution networks of developing countries such as Burkina Faso. A study was carried out on the distribution network of the city of Bobo-Dioulasso in Burkina Faso. It allowed for experimentation with the “Megger MPQ1000” network analyzer to evaluate the quality of the voltage supplied to households. To this end, tests were carried out in a public distribution station and at a few subscribers in the Sarfalao district of the city of Bobo-Dioulasso. These tests were used to assess the percentage of voltage drops. These values, which are higher than 8% of the nominal voltage, are not regulatory. The load curves of the consumers in the district were also drawn. Indeed, the period of the high load is between 19:00 and 23:00 Local Time (LT), while the period of the medium and low load is between 00:00 and 18:00 LT.展开更多
Practice training is very important for students learning Computer networks.But building a real laboratory is constrained and expensive.In this paper,we present an online experimental platform for computer networks co...Practice training is very important for students learning Computer networks.But building a real laboratory is constrained and expensive.In this paper,we present an online experimental platform for computer networks course based on Dynamips simulator.Instructors and students can access the platform by IE Browser to manage and take router experiments.On the basis of deployment and testing,the platform is effective and flexible.展开更多
The objective of this contribution is to present expositive review content on currently available experimental tools/services/concepts used for most emerging field Wireless Sensor Network that has capability to change...The objective of this contribution is to present expositive review content on currently available experimental tools/services/concepts used for most emerging field Wireless Sensor Network that has capability to change many of the Information Communication aspects in the upcoming era. Currently due to high cost of large number of sensor nodes most researches in wireless sensor networks area is performed by using these experimental tools in various universities, institutes, and research centers before implementing real one. Also the statistics gathered from these experimental tools can be realistic and convenient. These experimental tools provide the better option for studying the behavior of WSNs before and after implementing the physical one. In this contribution 63 simulators/simulation frameworks, 14 emulators, 19 data visualization tools, 46 testbeds, 26 debugging tools/services/concepts, 10 code-updation/reprogramming tools and 8 network monitors has been presented that are used worldwide for WSN researches.展开更多
基于网络药理学、分子对接及实验验证探究中药药对黄芪-党参(Astragali Radix-Codonopsis Radix,AR-CR)治疗动脉粥样硬化(atherosclerosis,AS)的分子作用机制。首先通过检索TCMSP、PubChem、SwissTargetPrediction、UniProt、GeneCards...基于网络药理学、分子对接及实验验证探究中药药对黄芪-党参(Astragali Radix-Codonopsis Radix,AR-CR)治疗动脉粥样硬化(atherosclerosis,AS)的分子作用机制。首先通过检索TCMSP、PubChem、SwissTargetPrediction、UniProt、GeneCards等数据库,获取中药药对AR-CR的活性成分,预测该药对的作用靶点,筛选动脉粥样硬化的相关靶点基因,然后利用Venny平台、STRING数据库、Cytoscape(Version 3.8.2)软件进行拓扑分析获取AR-CR治疗动脉粥样硬化的关键靶点,使用DAVID数据库对所获得的关键靶点进行GO和KEGG富集分析,并借助Auto Dock tools、Auto Dock cina对核心蛋白与活性成分完成分子对接,最后,利用氧化型低密度脂蛋白(oxidized low density lipoprotein,ox-LDL)诱导人脐静脉内皮细胞,建立AS细胞模型进行体外生物学验证。AR-CR共检索到34个活性化合物,并预测潜在化合物靶点426个,通过与875个AS靶点进行交际映射,获得AR-CR治疗AS关键靶点69个,筛选出3,9-二邻甲基苯胺、7-甲氧基-2-甲基异黄酮、5α-豆甾烷-3,6-二酮、木犀草素4个主要活性化合物,丝氨酸/苏氨酸蛋白激酶(serine/threonine-protein kinase,AKT1)、肿瘤蛋白p53(tumor protein p53,TP53)、丝裂原激活蛋白激酶3(mitogen-activated protein kinase 3,MAPK3)等25个核心靶点。KEGG通路富集分析得到关键通路为糖基化终末产物(advanced glycation end-product,AGE)/糖基化终末产物受体(receptor for advanced glycation endproduct,RAGE)信号通路和脂质与动脉粥样硬化信号通路等。分子对接结果显示4个主要活性化合物与核心靶点蛋白均能连接,其中与TP53的结合活性最强。体外实验结果表明低、中、高剂量的AR-CR能够促进动脉粥样硬化模型细胞增殖,抑制其凋亡,并促进TP53 mRNA及TP53蛋白表达。综上,该研究初步揭示AR-CR治疗AS的作用机制,与网络药理学及分子对接预测的TP53因子相关,通过调控TP53因子促进AS模型细胞增殖,抑制其凋亡,为临床治疗AS提供了理论基础。展开更多
The article introduces China Unicom's valuable experience obtained in the construction and operation of its IP-based data and fixed services network. In the construction of the network,China Unicom aimed at the qu...The article introduces China Unicom's valuable experience obtained in the construction and operation of its IP-based data and fixed services network. In the construction of the network,China Unicom aimed at the quick deployment of telecom-level integrated services by building up multi-level metropolitan area networks and access networks;in the operation of the network,China Unicorn made great efforts with equipment manufactures, software developers and system integration providers and achieved stable and improved network performance.展开更多
People create network virtual space that is completely different from the real space through network information technologies.The characteristics of network virtual space are that the subject can obtain a similar real...People create network virtual space that is completely different from the real space through network information technologies.The characteristics of network virtual space are that the subject can obtain a similar real space experience.From the perspective of phenomenology of technics,in order to analyze the virtual space of the network,it is necessary to clear the phenomenological concepts,such as space,space experience,and virtual space experience,so as to know the type of network virtual space experience,explore the essential characteristics,and find solutions to the ethical conflicts in the virtual space experience of the network.展开更多
This paper presents experimental results of a heterogeneous sensor network architecture, which is a combination of a wireless sensor network and a personal area network. The proposed architecture uses the IEEE 802.15....This paper presents experimental results of a heterogeneous sensor network architecture, which is a combination of a wireless sensor network and a personal area network. The proposed architecture uses the IEEE 802.15.4 standard to transmit sensor data to a sensor node which in turn forwards the data using TCP/IP to a database on the Internet via a Bluetooth-equipped mobile phone and the mobile telephone access network. The performance of the entire communication chain is evaluated. First, a 3G network's performance is evaluated by measuring its round trip time for packet transmission. Second, the real-world end-to-end delay between a sensor node and a database server on the Internet is measured using two different experimental set-ups: single-hop transmission and two hops transmission. Finally, the proposed architecture's scalability is estimated in a Matlab simulation using the results of the experiments as a base. The results show that the proposed architecture is applicable for small-scale sensor networks used by highly mobile users.展开更多
The ,Aspoe Pillar Stability Experiment （APSE） is an in situ experiment for investigating the spalling mechanism under mechanical and thermal loading conditions in a crystalline rock. In this study, the thermo-mechan...The ,Aspoe Pillar Stability Experiment （APSE） is an in situ experiment for investigating the spalling mechanism under mechanical and thermal loading conditions in a crystalline rock. In this study, the thermo-mechanical behaviors in the APSE were investigated with three models： （1） a Full model with rough meshes for calculating the influence of tunnel excavation; （2） a Submodel with fine meshes for predicting the thermo-mechanical behavior in the pillar during the borehole drilling, heating, and cool- ing phases; and （3） a Thin model for modeling the effect of slot cutting for de-stressing around the pillar. In order to import the stresses calculated from the Full model to the Submodel and to define the complex thermal boundary conditions, artificial neural networks （NNs） were utilized. From this study, it was pos- sible to conclude that the stepwise approach with the application of NNs was useful for predicting the complex response of the pillar under severe thermo-mechanical loading conditions.展开更多
Problem: A common assumption is that students prefer to select their friends for group-work. The prime goal of this study was to understand the impact of two group selection methods on how students from diverse cultur...Problem: A common assumption is that students prefer to select their friends for group-work. The prime goal of this study was to understand the impact of two group selection methods on how students from diverse cultural backgrounds build learning and work relations. Method: Social Network Analysis in a pre-post test manner in a quasi-experimental design of 81 vs. 70 third-year students. Solution: In this study, we “disrupted” this group selection process after Day 1 by balancing students from different parts of the social network together. In one condition the students were “balanced” into groups by staff to encourage structural hole formation, and in the other condition students were allowed to self-select their group members to encourage network closure. Results: Students in the self-selected condition primarily selected their friends from a similar cultural background. In both conditions the learning networks after 11 weeks were primarily predicted by the group allocation and initial friendships. However, students in the balanced condition developed more cross-cultural learning links. These results indicate that teachers can actively intervene in the cross-cultural dynamics in- and outside the classroom.展开更多
基金supported by University-level Teaching Reform Project of New Engineering,Beijing University of Chemical Technology(xgk2017040436)Teaching Reform Project of School of International Teaching,Beijing University of Chemical Technology(siejg201713)
文摘Digital circuit and analog circuit courses are basic courses for students of science and engineering universities. Among them,the practical courses are of great significance for students to master the knowledge of electronics. In order to make teachers teaching more efficiently and students studying more quickly,how to update the experimental course in teaching reform is the key point. This paper analyzing the present situation of teaching in the digital circuit and analog circuit courses,the teaching questions in universities. On the basis of it,the innovation measures of experimental teaching methods and contents are discussed. Our school tries to introduce the UltraLab network experiment platform,reform and optimize the teaching methods of related courses.And it’ s accelerating the construction and development of emerging engineering education’ s process,reducing effectively the teacher’s time for managing in equipment,improving the students’ ability to use instruments.
文摘The electrical energy produced must be consumed at the same time, hence the need to achieve a balance between supply and demand. Therefore, the production, transport, and distribution systems together constitute an electricity network. The distribution networks are designed to deliver energy to consumers. Unacceptable voltage drops are observed in the distribution networks of developing countries such as Burkina Faso. A study was carried out on the distribution network of the city of Bobo-Dioulasso in Burkina Faso. It allowed for experimentation with the “Megger MPQ1000” network analyzer to evaluate the quality of the voltage supplied to households. To this end, tests were carried out in a public distribution station and at a few subscribers in the Sarfalao district of the city of Bobo-Dioulasso. These tests were used to assess the percentage of voltage drops. These values, which are higher than 8% of the nominal voltage, are not regulatory. The load curves of the consumers in the district were also drawn. Indeed, the period of the high load is between 19:00 and 23:00 Local Time (LT), while the period of the medium and low load is between 00:00 and 18:00 LT.
文摘Practice training is very important for students learning Computer networks.But building a real laboratory is constrained and expensive.In this paper,we present an online experimental platform for computer networks course based on Dynamips simulator.Instructors and students can access the platform by IE Browser to manage and take router experiments.On the basis of deployment and testing,the platform is effective and flexible.
文摘The objective of this contribution is to present expositive review content on currently available experimental tools/services/concepts used for most emerging field Wireless Sensor Network that has capability to change many of the Information Communication aspects in the upcoming era. Currently due to high cost of large number of sensor nodes most researches in wireless sensor networks area is performed by using these experimental tools in various universities, institutes, and research centers before implementing real one. Also the statistics gathered from these experimental tools can be realistic and convenient. These experimental tools provide the better option for studying the behavior of WSNs before and after implementing the physical one. In this contribution 63 simulators/simulation frameworks, 14 emulators, 19 data visualization tools, 46 testbeds, 26 debugging tools/services/concepts, 10 code-updation/reprogramming tools and 8 network monitors has been presented that are used worldwide for WSN researches.
文摘基于网络药理学、分子对接及实验验证探究中药药对黄芪-党参(Astragali Radix-Codonopsis Radix,AR-CR)治疗动脉粥样硬化(atherosclerosis,AS)的分子作用机制。首先通过检索TCMSP、PubChem、SwissTargetPrediction、UniProt、GeneCards等数据库,获取中药药对AR-CR的活性成分,预测该药对的作用靶点,筛选动脉粥样硬化的相关靶点基因,然后利用Venny平台、STRING数据库、Cytoscape(Version 3.8.2)软件进行拓扑分析获取AR-CR治疗动脉粥样硬化的关键靶点,使用DAVID数据库对所获得的关键靶点进行GO和KEGG富集分析,并借助Auto Dock tools、Auto Dock cina对核心蛋白与活性成分完成分子对接,最后,利用氧化型低密度脂蛋白(oxidized low density lipoprotein,ox-LDL)诱导人脐静脉内皮细胞,建立AS细胞模型进行体外生物学验证。AR-CR共检索到34个活性化合物,并预测潜在化合物靶点426个,通过与875个AS靶点进行交际映射,获得AR-CR治疗AS关键靶点69个,筛选出3,9-二邻甲基苯胺、7-甲氧基-2-甲基异黄酮、5α-豆甾烷-3,6-二酮、木犀草素4个主要活性化合物,丝氨酸/苏氨酸蛋白激酶(serine/threonine-protein kinase,AKT1)、肿瘤蛋白p53(tumor protein p53,TP53)、丝裂原激活蛋白激酶3(mitogen-activated protein kinase 3,MAPK3)等25个核心靶点。KEGG通路富集分析得到关键通路为糖基化终末产物(advanced glycation end-product,AGE)/糖基化终末产物受体(receptor for advanced glycation endproduct,RAGE)信号通路和脂质与动脉粥样硬化信号通路等。分子对接结果显示4个主要活性化合物与核心靶点蛋白均能连接,其中与TP53的结合活性最强。体外实验结果表明低、中、高剂量的AR-CR能够促进动脉粥样硬化模型细胞增殖,抑制其凋亡,并促进TP53 mRNA及TP53蛋白表达。综上,该研究初步揭示AR-CR治疗AS的作用机制,与网络药理学及分子对接预测的TP53因子相关,通过调控TP53因子促进AS模型细胞增殖,抑制其凋亡,为临床治疗AS提供了理论基础。
文摘The article introduces China Unicom's valuable experience obtained in the construction and operation of its IP-based data and fixed services network. In the construction of the network,China Unicom aimed at the quick deployment of telecom-level integrated services by building up multi-level metropolitan area networks and access networks;in the operation of the network,China Unicorn made great efforts with equipment manufactures, software developers and system integration providers and achieved stable and improved network performance.
文摘People create network virtual space that is completely different from the real space through network information technologies.The characteristics of network virtual space are that the subject can obtain a similar real space experience.From the perspective of phenomenology of technics,in order to analyze the virtual space of the network,it is necessary to clear the phenomenological concepts,such as space,space experience,and virtual space experience,so as to know the type of network virtual space experience,explore the essential characteristics,and find solutions to the ethical conflicts in the virtual space experience of the network.
文摘This paper presents experimental results of a heterogeneous sensor network architecture, which is a combination of a wireless sensor network and a personal area network. The proposed architecture uses the IEEE 802.15.4 standard to transmit sensor data to a sensor node which in turn forwards the data using TCP/IP to a database on the Internet via a Bluetooth-equipped mobile phone and the mobile telephone access network. The performance of the entire communication chain is evaluated. First, a 3G network's performance is evaluated by measuring its round trip time for packet transmission. Second, the real-world end-to-end delay between a sensor node and a database server on the Internet is measured using two different experimental set-ups: single-hop transmission and two hops transmission. Finally, the proposed architecture's scalability is estimated in a Matlab simulation using the results of the experiments as a base. The results show that the proposed architecture is applicable for small-scale sensor networks used by highly mobile users.
基金within the context of the international DECOVALEX Project (DEvelopment of COupled models and their VALidation against EXperiments)supported by Korea Atomic Energy Research Institute (KAERI) as one of the Funding Organizations of the project,through the Nuclear Research and Development Program of KOSEF with a grant funded by MEST+3 种基金supported by Inha University Research Grant (INHA-44095-1)the support by Seoul National University (SNU)Swedish Nuclear Fuel and Waste Management Co. (SKB), Swedenprovided by SKB through its sp Pillar Stability Experiment project
文摘The ,Aspoe Pillar Stability Experiment （APSE） is an in situ experiment for investigating the spalling mechanism under mechanical and thermal loading conditions in a crystalline rock. In this study, the thermo-mechanical behaviors in the APSE were investigated with three models： （1） a Full model with rough meshes for calculating the influence of tunnel excavation; （2） a Submodel with fine meshes for predicting the thermo-mechanical behavior in the pillar during the borehole drilling, heating, and cool- ing phases; and （3） a Thin model for modeling the effect of slot cutting for de-stressing around the pillar. In order to import the stresses calculated from the Full model to the Submodel and to define the complex thermal boundary conditions, artificial neural networks （NNs） were utilized. From this study, it was pos- sible to conclude that the stepwise approach with the application of NNs was useful for predicting the complex response of the pillar under severe thermo-mechanical loading conditions.
文摘Problem: A common assumption is that students prefer to select their friends for group-work. The prime goal of this study was to understand the impact of two group selection methods on how students from diverse cultural backgrounds build learning and work relations. Method: Social Network Analysis in a pre-post test manner in a quasi-experimental design of 81 vs. 70 third-year students. Solution: In this study, we “disrupted” this group selection process after Day 1 by balancing students from different parts of the social network together. In one condition the students were “balanced” into groups by staff to encourage structural hole formation, and in the other condition students were allowed to self-select their group members to encourage network closure. Results: Students in the self-selected condition primarily selected their friends from a similar cultural background. In both conditions the learning networks after 11 weeks were primarily predicted by the group allocation and initial friendships. However, students in the balanced condition developed more cross-cultural learning links. These results indicate that teachers can actively intervene in the cross-cultural dynamics in- and outside the classroom.
