A CONTROL STUDY OF CLINICAL THERAPEUTIC EFFECTS OF LASER-ACUPUNCTURE ON DEPRESSIVE NEUROSIS

In this study, there were 62 patients with depressive neurosis. AInong them, 31 caseswere treated by laseracupuncture, another 31 cases were treated by pharmacotherapy, such as Antide-pressants and Antianxietics. The course of treatment for each case was 21 days. The therapeutic ef-fects, which were comprehensively evaluated with Hamilton’s Depression Scale (HAMD) and Hamil-ton’s Anxiety Scale (HAMI) as well as Clinical Global Impression Scale (CGI) in combination withtraditional evaluation of clinical therapeutic effect, indicated that treating the depressive neurosis withlaser-acupuncture can obtain sound effects with a clinical effective rate of 90. 32 percent, markedly ef-fective rate of 67. 74 percent. The global scores of Hamilton’s Depression Scale and Hamilton’s Anxi-ety scale after treatment were obviously less than those before treatment (P【0.001 ), similar to theeffects of pharmacotherapy or even much better than those in pharmacotherapy group in some aspects.Treating with laser-acupuncture

A CONTROL OBSERVATION ON THERAPEUTIC EFFECTS OF INTELLIGENT(COMPUTERIZED)ELECTROACUPUNCTURE AND COMMON ELECTROACUPUNCTURE TREATING 77 CASES OF NEUROSIS

77 cases of neurosis were treated with intelligent(computerized)elec-troacupuncture(IEA)and common electroacupuncture(CEA)at two different wave forms and fre-quencies.The results showed that the markedly effective rates of IEA and CEA were respectively75% and 60% without a statistically significant difference.For different subtypes of neurosis,thetherapeutic effects of IEC in the treatment 6f neurasthenia and depressive neurosis were superior toand in the treatment of anxiety was inferior to those of CEA.For different syndromes,the curativeeffects of IEA on somatic symptom,depression and asthenic symptom were.superior to and on anxietyand sleep-disorder were not as good as those of CEA.

Compatibility rule of traditional Chinese medicine for treatment of cardiac neurosis based on data mining

Objective:To analyze the prescription and medication rule of traditional Chinese medicine(TCM)in treating cardiac neurosis by using the software of"Traditional Chinese Medicine Inheritance Assistant Platform(V2.5)".Methods:China Journal Full-Text Database,Wanfang database,Weipu Chinese Periodical Service Platform and Chinese biomedical literature database were retrieved according to the inclusion and exclusion criteria.Literatures on the treatment of cardiac neurosis with TCM prescriptions were screened out and data mining was carried out using the TCM inheritance assistant platform.Use frequency,commonly used dose,the frequency of properties,flavors and meridian distribution were counted.Association rules and entropy clustering analysis for complex system were used to extract core drug combinations and unsupervised entropy hierarchical clustering was used to predict potential new prescriptions.Results:Through literature retrieval and screening,210 types of prescriptions were finally selected,and 181 types of Chinese herbs were extracted,with cumulative frequency of 2410 times.Among them,there were 46 traditional Chinese medicines that were used more than 15 times.According to the efficacy and indication,they were classified into qi-regulating drugs,tranquilizers,qi-tonifying drugs,heat-clearing drugs,blood-tonifying drugs,etc.According to properties,flavors,and meridian distribution,warm and sweet drugs were the most commonly used,mostly distributing to the heart meridian,followed by liver and spleen meridians.Association rules showed that combination of radix paeoniae and paeonia-bupleurum was the most used;faructus aurantii and bupleurum had the strongest correlation,up to 90%.The network diagram indicated that bupleurum,angelica sinensis,radix paeoniae radix,and poria cocos were the core of the association network.Based on complex system entropy clustering,24 core drug combinations were obtained.The unsupervised entropy hierarchical clustering algorithm was used to extract 12 core drug combinations,and 6 potential new formulae were obtained by further clustering.Conclusion:Regulating qi and blood,addressing both symptoms and causes,and using purgation and tonification at the same time is the principle of the treatment of cardiac neuropathy with TCM.The treatment mainly starts from the heart,liver and spleen,and therapies include soothing the liver and regulating qi,clearing heat and resolving phlegm,tranquilizing and calming the nerves,and prompting blood circulation and diuresis.

Neurosis

2010385 Regional homogeneity of hippocampus of major depressed patients before and after clinical recovery. WANG Li(王丽),et al. Nanjing Brain Hosp,Nanjing Med Univ,Nanjing. 210029. Chin J Nerv Ment Dis 2010;36(5):264-267. Objective The present study were to use fMRI to investigate the characteristics of the hippocampal activities of heavy depressed

Neurosis

2005284 Efficacy of venlafaxine on non-responders with major depressive disorder to selective serotonin reuptake inhibitors. YUAN Yong-gui (袁勇贵), et al. Dept Psychi, Affili Brain Hosp, Nanjing, Med limy, Nanjing 210029. Chin J Psychi,2005;38(1):27-29. Objective: To assess the efficacy of venlafaxine in outpatients who did not respond to selective serotonin reuptake inhibitors (SSRI) treatment. Meth-

Neurosis

2008490 Anxiety disease: decreased functional connectivity in left superior temporal gyrus (GTs) and right GTs. ZHAO Xiaohu(赵小虎), et al.Dept, Tongji Hosp, Tongji Univ, Shanghai 200065. Natl Med J China 2008;88(23):1603-1606. Objective To explore the characteristic of functional connectivity in anxiety disorders patient and the neural mechanism of this disease. This work was selected as an oral presentation in 2006 ISMRM.

兰州地区4868名大学生神经衰弱调查报告

神经衰弱是一种常见的神经症。1985年春,在原教育部等单位主持的“中国学生体质、健康调查研究”工作开展的同时,我们对兰州地区大专院校学生中的神经衰弱患病情况作了调查,现报告如下。

森田疗法门诊治疗15例难治性神经症疗效分析

用森田疗法治疗15例神经症,在治疗结束后治愈率和好转率分别为33.33％(5/15)和53.3％(8/15),在随访时治愈率和好转率分别为47.7％(7/15)和47.7％(7/15)。SCL—90分数以及社会功能亦有明显的改善。

Comorbidity between Neurotic Depression and Post-Traumatic Stress Disorder (PTSD)

Comorbidity with PTSD has been studied at home and abroad in follow-up studies following major traumatic events, indexing patients diagnosed with PTSD and investigating rates of comorbidity and other psychiatric disorders. In practical clinical practice, the majority of patients with PTSD are diagnosed with neurosis and depression, but the clinical manifestations and treatment of some of these patients are more complicated and difficult, and it is clinically found that these patients may have comorbidities and other mental disorders. This study in hospitalized patients with neurosis and depression as the main research object, through the investigation found that some patients (36.4%) of comorbid PTSD, just, this part of the patients reported by a traumatic event is not CCMD-3 defined in the “unusual” traumatic event. Therefore, the results of this study suggest that attention should be paid to the collection of patients’ medical history, especially the inquiry of traumatic experiences. This study is only a preliminary study with a small sample size, and the conclusions obtained need to be further confirmed in future studies.

The Neurotic Men: A Neo-Freudian Interpretation of The Bluest Eye

The Novel The Bluest Eye portrays several male characters who behave in neurotic ways. The Neo-Freudian psychoanalysis is employed to analyse Cholly, Junior and Soaphead Church, suggesting that they have the neurotic needs for power, affection and withdrawal respectively, thus helping develop the utilization of Neo-Freudian theory in the study of this novel.

Effect of Jin-3-Needling Therapy on Plasma Corticosteroid,Adrenocorticotrophic Hormone and Platelet 5-HT Levels in Patients with Generalized Anxiety Disorder

Objective： To observe the therapeutic efficacy of Jin-3-needling therapy （J3N） on generalized anxiety disorder （GAD） through clinical global impression scale （CGI）, and to explore the mechanism by measuring the plasma levels of corticosteroid （CS）, adrenocorticotrophic hormone （ACTH）, and platelet 5-hydroxytryptamine （5-HT） before and after treatment. Methods： Eightysix GAD patients with the diagnosis agreeing with the inclusion criteria were assigned, according to the sequence of visiting time, to three groups. The 29 patients in the Western medicine group were treated mainly with fluoxetine or paroxetine, Alprazolam might be given additionally in severe conditions if necessary; the 29 patients in the needling group received J3N therapy with Sishenzhen, Dingshenzhen, Neiguan （PC6）, Shenmen （HT7） and Sanyinjiao （SP6） as the chief acupoints selected; and the 28 patients in the combined treatment group were treated with both drugs and needling in the same way as applied in the above two groups. The therapeutic course for all was 6 weeks. Conditions of patients were evaluated before and after treatment with CGI, and levels of CS, ACTH as well as 5-HT were measured by high performance liquid chromatography-electrochemistry. Results： By CGI scoring, the scores of severity index and the general index were not different significantly in the three groups, but the efficacy index proved to be the highest in the needling group, the second in the combined trentment group, and the lowest in the drug group. Plasma level of ACTH and platelet content of 5-HT were lowered in all the three groups after treatment, showing statistical significance （P〈0.05）, but no significant change was found in CS level （P〉0.05）. Conclusion： The therapeutic efficacy of J3N in treating GAD is equivalent to, but with the efficacy index significantly higher than, that of conventional treatment. Moreover, when combined with drugs, needling might effectively prevent the side effect of the routinely used Western drugs. The regulatory action of needling on platelet 5-HT and plasma ACTH is probably one of the acting pathways for J3N treatment on GAD.

Preliminary Researeh on Treebel ot Oommon Mental Disorders with Oomputer Controlled Electroacupuncture

Electroacupuncturel (EA) lias proved as effective as amitriptyline in the treatment of depres-sion. The present article compared the therapeutic efficacy of electroacupuncture on common mental disorderand that of computer controlled electroacupuncture (CCEA) treatment of the samg disease. The resultsshowed that CCEA treatment had a better effect than EA for tbe treatment of single episode depression.CCEA treatment was generally superior to EA for the treatment of schizophrenia, depression and neurosis.The mechanism of CCEA for the treatment of common mental disorders was disciJssed.

Neurosi

2009265 Non-invasive MR perfusion study in patients with depression.LU Su(吕粟),et al.Huaxi MR Research Center,Dept Radiol,West China Hsop,Chengdu 610041.Chin J Radiol,2009;43(3):244-248.