The Congolese population is organised into households, which are thus headed by a chief who ensures the social well-being, development and integration into working life of the individuals in his charge. This study exa...The Congolese population is organised into households, which are thus headed by a chief who ensures the social well-being, development and integration into working life of the individuals in his charge. This study examines the functional principles of new housing design as an instrument for transforming the (current) failing economy into a strong and resilient one. Accordingly, a literature review of the practice of designing and building housing in human settlements in the Congo revealed the state of the art on this subject. An analysis of the existing housing stock from a demographic, social and economic point of view made it possible to identify the most common household sizes and numbers, as well as the lifestyle processes that determine the need for developed space. To this end, the experimental method was used to propose configuration plans for various new types of dwelling. To this end, the study highlighted the link between people’s standard of living and the effectiveness of their involvement in the local economy. To achieve the aims of the National Development Plan (NDP), particular attention must be paid to solving the housing problem. The existing housing stock actively contributes to the problems associated with unemployment and insecurity. Functional principles for the design of new types of housing have been developed. Four model types are proposed in line with the demographic structure of the population, their socio-economic characteristics and their lifestyle.展开更多
The clustered regularly interspaced short palindromic repeats(CRISPR)–CRISPR-associated protein(Cas) system has been widely used for genome editing. In this system, the cytosine base editor(CBE) and adenine base edit...The clustered regularly interspaced short palindromic repeats(CRISPR)–CRISPR-associated protein(Cas) system has been widely used for genome editing. In this system, the cytosine base editor(CBE) and adenine base editor(ABE) allow generating precise and irreversible base mutations in a programmable manner and have been used in many different types of cells and organisms. However, their applications are limited by low editing efficiency at certain genomic target sites or at specific target cytosine(C) or adenine(A) residues. Using a strategy of combining optimized synergistic core components, we developed a new multiplex super-assembled ABE(sABE) in rice that showed higher base-editing efficiency than previously developed ABEs. We also designed a new type of nuclear localization signal(NLS) comprising a FLAG epitope tag with four copies of a codon-optimized NLS(F4NLS^(r2)) to generate another ABE named F4NLS-sABE. This new NLS increased editing efficiency or edited additional A at several target sites. A new multiplex super-assembled CBE(sCBE) and F4NLS^(r2) involved F4NLS-sCBE were also created using the same strategy. F4NLS-sCBE was proven to be much more efficient than sCBE in rice. These optimized base editors will serve as powerful genome-editing tools for basic research or molecular breeding in rice and will provide a reference for the development of superior editing tools for other plants or animals.展开更多
A new kind of nematocyst, heteromorphore, and three new types of nematocysts, microbasic spino-mastigophore, microbasic undulata-mastigophore, microbasic laevis-mastigophore, are described from medusae of the Xiamen H...A new kind of nematocyst, heteromorphore, and three new types of nematocysts, microbasic spino-mastigophore, microbasic undulata-mastigophore, microbasic laevis-mastigophore, are described from medusae of the Xiamen Harbour and discussed by comparison with the results of other research workers.展开更多
This paper proposed several new types of finite-difference methods for the shallow water equation in absolute coordinate system and put forward an effective two-step predictor-corrector method, a compact and iterative...This paper proposed several new types of finite-difference methods for the shallow water equation in absolute coordinate system and put forward an effective two-step predictor-corrector method, a compact and iterative algorithm for five diagonal matrix. Then the iterative method was used for a multi-grid procedure for shallow water equation. A t last, an initial-boundary value problem was considered, and the numerical results show that the linear sinusoidal wave would successively evolve into conoidal wave.展开更多
Since the 18th National Congress of the Communist Party of China( CPC),with the help of state policies,the new types of agricultural businesses have been flourishing. As one of the important forces of new types of agr...Since the 18th National Congress of the Communist Party of China( CPC),with the help of state policies,the new types of agricultural businesses have been flourishing. As one of the important forces of new types of agricultural businesses,the farmer's specialized cooperatives grow up rapidly in the development of the rural economy because of their characteristics which are consistent with the current rural economy. financial management is the core of the operation of farmer cooperatives,which directly affects the long-term sustainable development of cooperatives. Through the survey and analysis of the financial management of many farmers' cooperatives in Wei County,Hebei Province,this paper puts forward the deficiencies in the existing financial management of cooperatives. It also brings some reasonable suggestions to regulate and improve the financial management of cooperatives,in order to enhance the market competitiveness of farmers' cooperatives and realize better sustainable development of farmers' cooperatives.展开更多
The new types of cybercrime have different features from traditional“cumulative crimes.”The application of the relevant provisions of the Criminal Law has run into difficulties,and the relevant theoretical explanati...The new types of cybercrime have different features from traditional“cumulative crimes.”The application of the relevant provisions of the Criminal Law has run into difficulties,and the relevant theoretical explanations of substantive preparatory crime and being an accomplice in crime find it hard to achieve self-consistency.Legislation on the new types of cybercrime is a legitimate response to recent changes in this area.Utilizing the particular techniques of cybercrime and the circumstantial requirement of limiting the amount of criminal harm is the key to satisfying the conditions for offences warranting criminal punishment.The harmfulness of the new types of cybercrime is not great;the law’s circumstantial requirements are flexible,and the criteria for judicial application are unclear,so the law’s provisions are seldom invoked and the sphere of criminal activity is unduly expanded.In order to give full play to the effectiveness of this legislation,we should formulate reasonable judicial rules that accord with the constitution of cybercrimes,narrow down the constituent elements of such crimes in a reasonable way,and categorize and limit the interpretation of circumstantial requirements.展开更多
AIM: To achieve a better understanding of the pathogenesis of new type gosling viral enteritis virus (NGVEV) and the relationship between NGVEV and host cells. METHODS: The apoptosis of duck embryo fibroblasts (DEF) i...AIM: To achieve a better understanding of the pathogenesis of new type gosling viral enteritis virus (NGVEV) and the relationship between NGVEV and host cells. METHODS: The apoptosis of duck embryo fibroblasts (DEF) induced by NGVEV was investigated by fluorescence-activated cell sorter (FACS) and fluorescence microscope after the cells were stained with Annexin V-FITC and propidium iodide (PI). RESULTS: By staining cells with a combination of fluorescein annexin V-FITC and PI, it is possible to distinguish and quantitatively analyze non-apoptotic cells (Annexin V-FITC negative/PI negative), early apoptotic cells (Annexin V-FITC positive/PI negative), late apoptotic/necrotic cells (Annexin V-FITC positive/ PI positive) and dead cells (Annexin V-FITC negative/PI positive) through flow cytometry and fluorescence microscope. The percentage of apoptotic cells increased with the incubation time and reached a maximum at 120 h after infection, while the percentage of non- apoptotic cells decreased.展开更多
Anatase and its allomorphic mineral rutile have the most prominent economic significance among titanium mineral resources and constitute one of the badly needed mineral resources currently in China. The Yantizishan-Mo...Anatase and its allomorphic mineral rutile have the most prominent economic significance among titanium mineral resources and constitute one of the badly needed mineral resources currently in China. The Yantizishan-Moshishan anatase deposit was formerly referred to as an iron deposit. Based on recent investigation and exploration the authors believe that it is actually a large metamorphosed sedimentary anatase-dominated deposit belonging to a new genetic type. Ore bodies occur in stratoid and lenticular forms in Mesoproterozoic (1751 Ma) schist, metasandstone (metasiltstone), and amphibolite. Rich ores have perthitic structure comprising chiefly interbedded quartz perthite (with disseminated anatase and rutile) and anatase perthite. Ore minerals are mainly anatase and subordinately rutile and ilmenite (±hematite), while nonmetallic minerals are chiefly quartz with a certain amount of anthophyllite and biotite (±garnet). The grain sizes of anatase, ruffle and ilmenite are 0.01-0.1 mm. Rich ores contain 3.14% to 15.46% TiO2. averaging 6.91%, while the low-grade ores have TiO2 content about 1.2%to 2.97%, averaging 1.76%. The ores have relatively high TFe and V contents. Trace elements in anatase and rutile such as Nb and Cr were analyzed by the electron microprobe. According to their relatively low Nb and Cr contents, source anatase and rutile must have come from meta-mafic rocks. Trace elements of the associated ilmenite show relatively high MnO and low MgO contents, just in contrast to those of ilmenite in V-Ti-magnetite ores of magmatic origin. The protoliths of amphibolite wall rocks should be basalt and picrite-basalt. Pertochemical data suggest that the tectonic setting of these rocks belongs to an island arc or a transitional belt between the island arc and oceanic ridge. Silicon isotope study shows that δ30Si values of different anatase ores, quartzite, and schist in this deposit are 0.1‰ to -0.9‰, similar to those of marine hydrothermal exhalative sedimentary deposits. All of these geological and geochemical characteristics of the ore deposit suggest that the anatase ores and amphibolite are products of submarine basic volcanism. The ores had chemical precipitation features, but were later subjected to regional intermediate (or somewhat lower) grade metamorphism (1158 Ma). Rutile was formed mainly in the process of this metamorphism. The ore belt locally underwent hydrothermal modification during the emplacement of Late Yanshanian granite (118 Ma).展开更多
In this paper, a photoelectric signal obtained scheme via equator triangle pattern engraved on rotor is discussed and the mathematic model is deduced in the case which is deflexion between rotor axis and the coordinat...In this paper, a photoelectric signal obtained scheme via equator triangle pattern engraved on rotor is discussed and the mathematic model is deduced in the case which is deflexion between rotor axis and the coordinate frame of case. The deflexion error and coupling error under the situation are analyzed. Finally, three methods of engraving based on the spherical triangle pattern are presented. The error models of various methods are built up and the simulation curves are provided respectively. We have done the primary experiments on the surface of rotor using this method. It can be seen from the enlarged figures that the rim of the pattern is smooth and the demand of sensor resolution is satisfied by and large. The results of study supply reference for signal obtaining.展开更多
Both new plant type (NPT) and intersubspecific hybrid rice (IHR) had large sink size (total number of spikelets per m2), however, poor grain filling limited their potential in the grain yield. Compared to the three-li...Both new plant type (NPT) and intersubspecific hybrid rice (IHR) had large sink size (total number of spikelets per m2), however, poor grain filling limited their potential in the grain yield. Compared to the three-line indica hybrid of Shanyou 63 (CK), NPT and IHR showed higher photosynthetic potential, higher dry matter accumulation and higher ratio of dry weight to spikelets (total dry wt./total number of spikelets) from heading to harvest. But both exhibited a low export percentage and transfer ratio of assimilates, low partitioning of 14C to grains from labeled flag leaves, low harvest indices and low physiological activities (IAA content and activities of ATPase and starch synthase) of grains at early grain-filling stage. The physiological activities of grains at early filling stage were significantly correlated with the export percentage and transfer ratio of assimilates, ripened-grain percentage and grain plumpness (r = 0.85 - 0.95). The source-sink ratio (dry matter wt./spikelet and nonstructural carbohydrate/spikelet) at heading was positively correlated with physiological activities of grains (r = 0. 84 - 0. 97 ). It is suggested that low physiological activities of grains at early filling stage is attributed to low source-sink ratio at heading, and the low sink activity weakens the ability to remobilize assimilates into grains, and leads to poor grain filling in NPT and IHR.展开更多
Numerical simulation was used to estimate the temperature field within a poured concrete,mono-layer freezing-shaft lining.The affects from various factors were investigated.The maximum temperature within the lining in...Numerical simulation was used to estimate the temperature field within a poured concrete,mono-layer freezing-shaft lining.The affects from various factors were investigated.The maximum temperature within the lining increases as the lining thickness increases,decreases as the soil-side wall temperature decreases,decreases as the air temperature inside the shaft decreases and decreases as the air velocity inside the shaft increases.The compression speed of an insulating foam layer affects the maximum temperature difference between the interior and the sidewalls.The maximum temperature difference between the interior and the sidewalls approaches or exceeds the maximum allowable for the curing of poured concrete structures.Attention should be paid to the question of the lining cracking during the curing period.The temperature gradient in the vertical direction may be minimized by preventing air contact against the steel connection board supporting the base of the freshly poured section.展开更多
The South China Sea (SCS), in particular the northern SCS, is one of ocean areas where energetic internal solitary waves (ISWs)occur most frequently (Cai et al., 2012; Zheng, 2017). Based on the re-appearance pe...The South China Sea (SCS), in particular the northern SCS, is one of ocean areas where energetic internal solitary waves (ISWs)occur most frequently (Cai et al., 2012; Zheng, 2017). Based on the re-appearance period (RP) at an observation station, Ramp et al.(2004) divided the ISWs into two types:Type-a and Type-b. Type-a ISWs arrive regularly at the same time every day, i.e., the RP is about 24 h, and Type-b ISWs arrive about one hour late every day, i.e., the RP is about 25 h.展开更多
The discovery of new-type ore deposits, an important approach to guarantee the mineral resources supply in the 21st century, often brings about a gigantic increase in the mineral resources reserves. The analysis of mi...The discovery of new-type ore deposits, an important approach to guarantee the mineral resources supply in the 21st century, often brings about a gigantic increase in the mineral resources reserves. The analysis of mineralization system is of great importance to the discovery of new type ore deposits. ① The understanding of the relationship among various ore deposit types within a mineralization system in a region can help us to locate the unknown ore deposit types from the known ore deposit types, evidence that has been proved in the mineral prospecting history of ore belts in the middle and lower reaches of the Yangtze River, China. ② The understanding of the spatial structure of a mineralization system, especially of the vertical zonation, is helpful for the discovery of the concealed ore deposit types. ③ Clarifying the temporal structure of a mineralization system, including the iteration relationship between the mineral deposit types in the mineralization, leads to the location of the missing mineralization chains from the known mineralization chains (mineral deposit type), a method often proved to be effective in the magmatic hydrothermal mineralization system.④ Clarifying the factors restraining the diversity of mineral deposit types in mineralization system leads to the discovery of the potential of new type mineral deposits in relevant region. ⑤ Studying new mineralization setting and new ore forming processes leads to discovery of new type mineral deposit. More probabilities of discovery of new type mineral deposits are present in biogenic mineralization system, deep sea mineralization system, low temperature mineralization system, tectonic mineralization system and superimposed mineralization system.展开更多
1-substituted-5-benzoylamino-4-pyrazolecarboxamides(2)were prepared by the reaction of 1-substituted pyrazolo[3,4-d]-oxazinone(1) with amines in benzene.The compound 2 was refluxed with excess LiAlH_4 in a mixture of ...1-substituted-5-benzoylamino-4-pyrazolecarboxamides(2)were prepared by the reaction of 1-substituted pyrazolo[3,4-d]-oxazinone(1) with amines in benzene.The compound 2 was refluxed with excess LiAlH_4 in a mixture of THF and ether,one of the two carbamoyl groups in the molecule 2 was reduced selectively.As the results,1-substituted-5- benzylamino-4-pyrazolecarboxamides(3)were obtained.Compounds 3 reacted with Cl_2PPh-X,or P(NET_2)_3,producing the title compounds(4). The conditions of the reactions were studied.展开更多
Recently Yang,Chu,and Han [Phys.Rev.A 70 (2004) 022329] presented a new type of multipartiteentangled states for implementing efficient many-party controlled teleportation of multiqubit quantum information.Herewe prop...Recently Yang,Chu,and Han [Phys.Rev.A 70 (2004) 022329] presented a new type of multipartiteentangled states for implementing efficient many-party controlled teleportation of multiqubit quantum information.Herewe propose a simple scheme for preparing such a type of multi-atom entangled states in cavity quantum electrodynamics(QED).The scheme involves atom-cavity interaction with large detuning,and is immune to the cavity decay and thethermal field states.Some practical analyses show its availability with the present technology.展开更多
A new type of conserved quantity, which is induced from the Mei symmetry of Lagrange systems, is studied. The conditions for that the new type of conserved quantity exists and the form of the new type of conserved qua...A new type of conserved quantity, which is induced from the Mei symmetry of Lagrange systems, is studied. The conditions for that the new type of conserved quantity exists and the form of the new type of conserved quantity are obtained. An illustrated example is given. The Noether conserved quantity induced from the Mei symmetry of Lagrange systems is a special case of the new type of conserved quantity given in this paper.展开更多
Along with the rapid advance of industrialization and urbanization process, fostering new agricultural business entities become inevitable for agricultural transformation and the construction of agricultural moderniza...Along with the rapid advance of industrialization and urbanization process, fostering new agricultural business entities become inevitable for agricultural transformation and the construction of agricultural modernization in China. The status of the new agricultural business entities determines the level of modern agricultural development. In recent years, new agricultural business entities have grew rapidly. However, there are still many problems including the difficulties in financing loans, inadequate agricultural insurance system, bad implementation of agricultural subsidies, jagged agricultural talents and so on. In order to foster new agricultural business entities, countermeasures should be carried out to ensure financial support, perfect the agricultural insurance, strengthen the level of agricultural subsidies, strive to develop the degree of specialization agricultural operators and so on.展开更多
Objective: To replace the peripheral venous puncture for blood sampling with taking blood samples extracorporally from arterial line before predilution during RCA-CRRT performed. Methods: A new type of double-lumen fe...Objective: To replace the peripheral venous puncture for blood sampling with taking blood samples extracorporally from arterial line before predilution during RCA-CRRT performed. Methods: A new type of double-lumen femoral catheter was used instead of the current tubes. The new type of double-lumen tube had a greater distance from the inner venous ports to the inner arterial ports than current tubes. The minimum distance from the venous port to the arterial port was greatly lengthened. Replacement solution contained citrate, zero Ca<sup>2+</sup>, zero bicarbonate, low Na<sup>+</sup>. Blood samples were synchronously collected from the arterial line before the infusion of citrate replacement fluid and from the peripheral vein. The iCa concentration data of two groups were analyzed to observe the difference between iCa concentration levels in the arterial line and in peripheral vein;the anticoagulant effect of RCA and possible complications were observed, such as bleeding, clottings and hypocalcaemia. Results: 28 times of RCA-CRRT were performed on17 AKI and CRF patients with active bleeding or at the high risk of bleeding;336 blood samples were collected. Statistics showed that the difference of iCa concentration between arterial line group and the peripheral vein group was not significant (P = 0.9), there is a high degree of similarity between the iCa concentration of arterial line blood and the peripheral venous blood. None of the patients developed citrate toxicity or metabolic alkalosis. None induced bleeding, or bleeding aggravated. No obvious clotting occurred. Systemic calcium concentration was achieved in the ideal range. Conclusion: In clinical practice, the data of iCa concentration from arterial line can be used to replace that from peripheral vein when the new type of double-lumen femoral catheter is placed in femoral vein. RCA-CRRT therapy is safe and effective.展开更多
文摘The Congolese population is organised into households, which are thus headed by a chief who ensures the social well-being, development and integration into working life of the individuals in his charge. This study examines the functional principles of new housing design as an instrument for transforming the (current) failing economy into a strong and resilient one. Accordingly, a literature review of the practice of designing and building housing in human settlements in the Congo revealed the state of the art on this subject. An analysis of the existing housing stock from a demographic, social and economic point of view made it possible to identify the most common household sizes and numbers, as well as the lifestyle processes that determine the need for developed space. To this end, the experimental method was used to propose configuration plans for various new types of dwelling. To this end, the study highlighted the link between people’s standard of living and the effectiveness of their involvement in the local economy. To achieve the aims of the National Development Plan (NDP), particular attention must be paid to solving the housing problem. The existing housing stock actively contributes to the problems associated with unemployment and insecurity. Functional principles for the design of new types of housing have been developed. Four model types are proposed in line with the demographic structure of the population, their socio-economic characteristics and their lifestyle.
基金supported by the Beijing Scholars Program[BSP041]。
文摘The clustered regularly interspaced short palindromic repeats(CRISPR)–CRISPR-associated protein(Cas) system has been widely used for genome editing. In this system, the cytosine base editor(CBE) and adenine base editor(ABE) allow generating precise and irreversible base mutations in a programmable manner and have been used in many different types of cells and organisms. However, their applications are limited by low editing efficiency at certain genomic target sites or at specific target cytosine(C) or adenine(A) residues. Using a strategy of combining optimized synergistic core components, we developed a new multiplex super-assembled ABE(sABE) in rice that showed higher base-editing efficiency than previously developed ABEs. We also designed a new type of nuclear localization signal(NLS) comprising a FLAG epitope tag with four copies of a codon-optimized NLS(F4NLS^(r2)) to generate another ABE named F4NLS-sABE. This new NLS increased editing efficiency or edited additional A at several target sites. A new multiplex super-assembled CBE(sCBE) and F4NLS^(r2) involved F4NLS-sCBE were also created using the same strategy. F4NLS-sCBE was proven to be much more efficient than sCBE in rice. These optimized base editors will serve as powerful genome-editing tools for basic research or molecular breeding in rice and will provide a reference for the development of superior editing tools for other plants or animals.
文摘A new kind of nematocyst, heteromorphore, and three new types of nematocysts, microbasic spino-mastigophore, microbasic undulata-mastigophore, microbasic laevis-mastigophore, are described from medusae of the Xiamen Harbour and discussed by comparison with the results of other research workers.
文摘This paper proposed several new types of finite-difference methods for the shallow water equation in absolute coordinate system and put forward an effective two-step predictor-corrector method, a compact and iterative algorithm for five diagonal matrix. Then the iterative method was used for a multi-grid procedure for shallow water equation. A t last, an initial-boundary value problem was considered, and the numerical results show that the linear sinusoidal wave would successively evolve into conoidal wave.
基金Supported by Tender Project of Agricultural University of Hebei Province(ZB201702)Research on Mechanism Innovation and Path Selection of Precise Poverty Alleviation-Based on Survey of 62 Poor Counties in Hebei Province&Social Science Fund Bidding Project of Agricultural University of Hebei Province in 2017(2016JD02)+3 种基金Research on Model and Mechanism Innovation of Industrial Precision Poverty Alleviation&Hebei Social Science Foundation Project(HB15GL072)Research on Innovative Path of Cultivating Mechanism of New Professional Farmers in Yanshan-Taihang Mountain Area under the Coordinated Development of Beijing,Tianjin and Hebei&Key Project of Hebei Provincial Department of Education(SD151020)Cultivation of New Professional Farmers in Hebei Province-Research on Concept,Mechanism and Path Innovation&Baoding Social Science Union Project(201501017)Research on Cultivation of New Professional Farmers in Yanshan-Taihang Mountain Area and Integration of "Two New"-Based on the View of Coordinated Development of Beijing,Tianjin and Hebei
文摘Since the 18th National Congress of the Communist Party of China( CPC),with the help of state policies,the new types of agricultural businesses have been flourishing. As one of the important forces of new types of agricultural businesses,the farmer's specialized cooperatives grow up rapidly in the development of the rural economy because of their characteristics which are consistent with the current rural economy. financial management is the core of the operation of farmer cooperatives,which directly affects the long-term sustainable development of cooperatives. Through the survey and analysis of the financial management of many farmers' cooperatives in Wei County,Hebei Province,this paper puts forward the deficiencies in the existing financial management of cooperatives. It also brings some reasonable suggestions to regulate and improve the financial management of cooperatives,in order to enhance the market competitiveness of farmers' cooperatives and realize better sustainable development of farmers' cooperatives.
文摘The new types of cybercrime have different features from traditional“cumulative crimes.”The application of the relevant provisions of the Criminal Law has run into difficulties,and the relevant theoretical explanations of substantive preparatory crime and being an accomplice in crime find it hard to achieve self-consistency.Legislation on the new types of cybercrime is a legitimate response to recent changes in this area.Utilizing the particular techniques of cybercrime and the circumstantial requirement of limiting the amount of criminal harm is the key to satisfying the conditions for offences warranting criminal punishment.The harmfulness of the new types of cybercrime is not great;the law’s circumstantial requirements are flexible,and the criteria for judicial application are unclear,so the law’s provisions are seldom invoked and the sphere of criminal activity is unduly expanded.In order to give full play to the effectiveness of this legislation,we should formulate reasonable judicial rules that accord with the constitution of cybercrimes,narrow down the constituent elements of such crimes in a reasonable way,and categorize and limit the interpretation of circumstantial requirements.
基金The National Natural Science Foundation of China, No. 39970561The Key Projects in the National Science and Technology Pillar Program, 2007Z06-017+2 种基金Program for New Century Excellent Talents from Universities, Chinese Ministry of Education, No. NCET-04-0906/NCET-06-0818Fund of the Discipline Leaders of Sichuan Province, No. SZD0418Culture Fund for Excellent Doctoral Dissertations of Sichuan Agricultural University, 2008scybpy-1
文摘AIM: To achieve a better understanding of the pathogenesis of new type gosling viral enteritis virus (NGVEV) and the relationship between NGVEV and host cells. METHODS: The apoptosis of duck embryo fibroblasts (DEF) induced by NGVEV was investigated by fluorescence-activated cell sorter (FACS) and fluorescence microscope after the cells were stained with Annexin V-FITC and propidium iodide (PI). RESULTS: By staining cells with a combination of fluorescein annexin V-FITC and PI, it is possible to distinguish and quantitatively analyze non-apoptotic cells (Annexin V-FITC negative/PI negative), early apoptotic cells (Annexin V-FITC positive/PI negative), late apoptotic/necrotic cells (Annexin V-FITC positive/ PI positive) and dead cells (Annexin V-FITC negative/PI positive) through flow cytometry and fluorescence microscope. The percentage of apoptotic cells increased with the incubation time and reached a maximum at 120 h after infection, while the percentage of non- apoptotic cells decreased.
基金the National Natural Science Foundation of China(Grant 40773038)Geological Exploration Project Office of Inner Mongolia (05-1-TK01)the Institute of Mineral Resources, Chinese Academy of Geological Sciences(K0714)
文摘Anatase and its allomorphic mineral rutile have the most prominent economic significance among titanium mineral resources and constitute one of the badly needed mineral resources currently in China. The Yantizishan-Moshishan anatase deposit was formerly referred to as an iron deposit. Based on recent investigation and exploration the authors believe that it is actually a large metamorphosed sedimentary anatase-dominated deposit belonging to a new genetic type. Ore bodies occur in stratoid and lenticular forms in Mesoproterozoic (1751 Ma) schist, metasandstone (metasiltstone), and amphibolite. Rich ores have perthitic structure comprising chiefly interbedded quartz perthite (with disseminated anatase and rutile) and anatase perthite. Ore minerals are mainly anatase and subordinately rutile and ilmenite (±hematite), while nonmetallic minerals are chiefly quartz with a certain amount of anthophyllite and biotite (±garnet). The grain sizes of anatase, ruffle and ilmenite are 0.01-0.1 mm. Rich ores contain 3.14% to 15.46% TiO2. averaging 6.91%, while the low-grade ores have TiO2 content about 1.2%to 2.97%, averaging 1.76%. The ores have relatively high TFe and V contents. Trace elements in anatase and rutile such as Nb and Cr were analyzed by the electron microprobe. According to their relatively low Nb and Cr contents, source anatase and rutile must have come from meta-mafic rocks. Trace elements of the associated ilmenite show relatively high MnO and low MgO contents, just in contrast to those of ilmenite in V-Ti-magnetite ores of magmatic origin. The protoliths of amphibolite wall rocks should be basalt and picrite-basalt. Pertochemical data suggest that the tectonic setting of these rocks belongs to an island arc or a transitional belt between the island arc and oceanic ridge. Silicon isotope study shows that δ30Si values of different anatase ores, quartzite, and schist in this deposit are 0.1‰ to -0.9‰, similar to those of marine hydrothermal exhalative sedimentary deposits. All of these geological and geochemical characteristics of the ore deposit suggest that the anatase ores and amphibolite are products of submarine basic volcanism. The ores had chemical precipitation features, but were later subjected to regional intermediate (or somewhat lower) grade metamorphism (1158 Ma). Rutile was formed mainly in the process of this metamorphism. The ore belt locally underwent hydrothermal modification during the emplacement of Late Yanshanian granite (118 Ma).
文摘In this paper, a photoelectric signal obtained scheme via equator triangle pattern engraved on rotor is discussed and the mathematic model is deduced in the case which is deflexion between rotor axis and the coordinate frame of case. The deflexion error and coupling error under the situation are analyzed. Finally, three methods of engraving based on the spherical triangle pattern are presented. The error models of various methods are built up and the simulation curves are provided respectively. We have done the primary experiments on the surface of rotor using this method. It can be seen from the enlarged figures that the rim of the pattern is smooth and the demand of sensor resolution is satisfied by and large. The results of study supply reference for signal obtaining.
文摘Both new plant type (NPT) and intersubspecific hybrid rice (IHR) had large sink size (total number of spikelets per m2), however, poor grain filling limited their potential in the grain yield. Compared to the three-line indica hybrid of Shanyou 63 (CK), NPT and IHR showed higher photosynthetic potential, higher dry matter accumulation and higher ratio of dry weight to spikelets (total dry wt./total number of spikelets) from heading to harvest. But both exhibited a low export percentage and transfer ratio of assimilates, low partitioning of 14C to grains from labeled flag leaves, low harvest indices and low physiological activities (IAA content and activities of ATPase and starch synthase) of grains at early grain-filling stage. The physiological activities of grains at early filling stage were significantly correlated with the export percentage and transfer ratio of assimilates, ripened-grain percentage and grain plumpness (r = 0.85 - 0.95). The source-sink ratio (dry matter wt./spikelet and nonstructural carbohydrate/spikelet) at heading was positively correlated with physiological activities of grains (r = 0. 84 - 0. 97 ). It is suggested that low physiological activities of grains at early filling stage is attributed to low source-sink ratio at heading, and the low sink activity weakens the ability to remobilize assimilates into grains, and leads to poor grain filling in NPT and IHR.
基金provided by the Office of National Science and Technology (No.2006BAB16B01)the Physics Program of the Henan Province Education Department (No.2009B 560004)the Doctoral Fund of Henan Polytechnic University (No.648234)
文摘Numerical simulation was used to estimate the temperature field within a poured concrete,mono-layer freezing-shaft lining.The affects from various factors were investigated.The maximum temperature within the lining increases as the lining thickness increases,decreases as the soil-side wall temperature decreases,decreases as the air temperature inside the shaft decreases and decreases as the air velocity inside the shaft increases.The compression speed of an insulating foam layer affects the maximum temperature difference between the interior and the sidewalls.The maximum temperature difference between the interior and the sidewalls approaches or exceeds the maximum allowable for the curing of poured concrete structures.Attention should be paid to the question of the lining cracking during the curing period.The temperature gradient in the vertical direction may be minimized by preventing air contact against the steel connection board supporting the base of the freshly poured section.
基金The National Science and Technology Major Project of China under contract No.2016ZX05057015the National Natural Science Foundation of China under contract Nos 41376038 and 40406009+3 种基金the NSFC-Shandong Joint Fund for Marine Science Research Centers of China under contract No.U1606405the National Program on Global Change and Air-Sea Interaction of China under contract Nos GASI-03-01-01-02,GASI-02-IND-STSsum and GASI-IPOVAI-01-05the Public Science and Technology Research Funds Projects of Ocean of China under contract No.200905024the National Key Scientific Instrument and Equipment Development Projects of China under contract No.2012YQ12003908
文摘The South China Sea (SCS), in particular the northern SCS, is one of ocean areas where energetic internal solitary waves (ISWs)occur most frequently (Cai et al., 2012; Zheng, 2017). Based on the re-appearance period (RP) at an observation station, Ramp et al.(2004) divided the ISWs into two types:Type-a and Type-b. Type-a ISWs arrive regularly at the same time every day, i.e., the RP is about 24 h, and Type-b ISWs arrive about one hour late every day, i.e., the RP is about 25 h.
文摘The discovery of new-type ore deposits, an important approach to guarantee the mineral resources supply in the 21st century, often brings about a gigantic increase in the mineral resources reserves. The analysis of mineralization system is of great importance to the discovery of new type ore deposits. ① The understanding of the relationship among various ore deposit types within a mineralization system in a region can help us to locate the unknown ore deposit types from the known ore deposit types, evidence that has been proved in the mineral prospecting history of ore belts in the middle and lower reaches of the Yangtze River, China. ② The understanding of the spatial structure of a mineralization system, especially of the vertical zonation, is helpful for the discovery of the concealed ore deposit types. ③ Clarifying the temporal structure of a mineralization system, including the iteration relationship between the mineral deposit types in the mineralization, leads to the location of the missing mineralization chains from the known mineralization chains (mineral deposit type), a method often proved to be effective in the magmatic hydrothermal mineralization system.④ Clarifying the factors restraining the diversity of mineral deposit types in mineralization system leads to the discovery of the potential of new type mineral deposits in relevant region. ⑤ Studying new mineralization setting and new ore forming processes leads to discovery of new type mineral deposit. More probabilities of discovery of new type mineral deposits are present in biogenic mineralization system, deep sea mineralization system, low temperature mineralization system, tectonic mineralization system and superimposed mineralization system.
基金Project supported by National Natural Science Foundation of China.
文摘1-substituted-5-benzoylamino-4-pyrazolecarboxamides(2)were prepared by the reaction of 1-substituted pyrazolo[3,4-d]-oxazinone(1) with amines in benzene.The compound 2 was refluxed with excess LiAlH_4 in a mixture of THF and ether,one of the two carbamoyl groups in the molecule 2 was reduced selectively.As the results,1-substituted-5- benzylamino-4-pyrazolecarboxamides(3)were obtained.Compounds 3 reacted with Cl_2PPh-X,or P(NET_2)_3,producing the title compounds(4). The conditions of the reactions were studied.
基金the Natural Science Foundation of Hunan Province under Grant No.06JJ5015the Scientific Research Fund of the Education Department of Hunan Province under Grant No.06C354
文摘Recently Yang,Chu,and Han [Phys.Rev.A 70 (2004) 022329] presented a new type of multipartiteentangled states for implementing efficient many-party controlled teleportation of multiqubit quantum information.Herewe propose a simple scheme for preparing such a type of multi-atom entangled states in cavity quantum electrodynamics(QED).The scheme involves atom-cavity interaction with large detuning,and is immune to the cavity decay and thethermal field states.Some practical analyses show its availability with the present technology.
文摘A new type of conserved quantity, which is induced from the Mei symmetry of Lagrange systems, is studied. The conditions for that the new type of conserved quantity exists and the form of the new type of conserved quantity are obtained. An illustrated example is given. The Noether conserved quantity induced from the Mei symmetry of Lagrange systems is a special case of the new type of conserved quantity given in this paper.
基金Supported by the National Social Science Fund(13CJY079)the National Natural Science Fund(71303039)
文摘Along with the rapid advance of industrialization and urbanization process, fostering new agricultural business entities become inevitable for agricultural transformation and the construction of agricultural modernization in China. The status of the new agricultural business entities determines the level of modern agricultural development. In recent years, new agricultural business entities have grew rapidly. However, there are still many problems including the difficulties in financing loans, inadequate agricultural insurance system, bad implementation of agricultural subsidies, jagged agricultural talents and so on. In order to foster new agricultural business entities, countermeasures should be carried out to ensure financial support, perfect the agricultural insurance, strengthen the level of agricultural subsidies, strive to develop the degree of specialization agricultural operators and so on.
文摘Objective: To replace the peripheral venous puncture for blood sampling with taking blood samples extracorporally from arterial line before predilution during RCA-CRRT performed. Methods: A new type of double-lumen femoral catheter was used instead of the current tubes. The new type of double-lumen tube had a greater distance from the inner venous ports to the inner arterial ports than current tubes. The minimum distance from the venous port to the arterial port was greatly lengthened. Replacement solution contained citrate, zero Ca<sup>2+</sup>, zero bicarbonate, low Na<sup>+</sup>. Blood samples were synchronously collected from the arterial line before the infusion of citrate replacement fluid and from the peripheral vein. The iCa concentration data of two groups were analyzed to observe the difference between iCa concentration levels in the arterial line and in peripheral vein;the anticoagulant effect of RCA and possible complications were observed, such as bleeding, clottings and hypocalcaemia. Results: 28 times of RCA-CRRT were performed on17 AKI and CRF patients with active bleeding or at the high risk of bleeding;336 blood samples were collected. Statistics showed that the difference of iCa concentration between arterial line group and the peripheral vein group was not significant (P = 0.9), there is a high degree of similarity between the iCa concentration of arterial line blood and the peripheral venous blood. None of the patients developed citrate toxicity or metabolic alkalosis. None induced bleeding, or bleeding aggravated. No obvious clotting occurred. Systemic calcium concentration was achieved in the ideal range. Conclusion: In clinical practice, the data of iCa concentration from arterial line can be used to replace that from peripheral vein when the new type of double-lumen femoral catheter is placed in femoral vein. RCA-CRRT therapy is safe and effective.