Background A prospective 2-night polysomnographic （PSG） study in Chinese snorers was designed to assess the role of the first night effect （FNE） in PSG parameters and the diagnosis of obstructive sleep apnea hypop...Background A prospective 2-night polysomnographic （PSG） study in Chinese snorers was designed to assess the role of the first night effect （FNE） in PSG parameters and the diagnosis of obstructive sleep apnea hypopnea syndrome （OSAHS）.Methods Seventy-two snorers from two teaching hospitals underwent overnight PSG on two consecutive nights. I he night-to-night variability of PSG parameters were recorded and analyzed.Results Sixty-six patients were analyzed. Among all the PSG parameters, only the total time of stage 2 presented a significant difference between two nights： 219.50 （83.50-353.50） vs. 215.25 （59.50-342.50） （P=0.000）. Subgroup assessment showed a slight night-to-night difference in about 1-2 parameters in the group with the apnea-hypopnea index （AHI） -〉20 events per hour as well as the group with AHI 〈20 events per hour, but there was no night-to-night difference in the AHI in each group. And slighter FNE was found among patients -〉40 years old. There was no significant difference in diagnosis of OSAHS. In the decision of severity, a slight difference was found between the two nights with a Kappa value=0.531.Conclusions Only mild FNE can be found on two consecutive nights of PSG in adult Chinese snorers, but it has no effect on the diagnosis of OSAHS. A single polysomnographic night may be adequate for the diagnosis of OSAHS.展开更多
目的:比较夜戴型角膜塑形镜与框架眼镜治疗青少年近视效果,为青少年近视治疗方法选择提供参考。方法:前瞻性研究。选择2020-06/11在我院接受治疗的青少年近视患者106例。根据患者意愿将其分为两组:对照组53例在验光后给予常规框架眼镜治...目的:比较夜戴型角膜塑形镜与框架眼镜治疗青少年近视效果,为青少年近视治疗方法选择提供参考。方法:前瞻性研究。选择2020-06/11在我院接受治疗的青少年近视患者106例。根据患者意愿将其分为两组:对照组53例在验光后给予常规框架眼镜治疗,观察组53例则给予夜戴型角膜塑形镜治疗。比较两组患者治疗前后裸眼视力(LogMAR)、验光指标(等效球镜度数、柱镜度数)、眼生物学参数(眼轴长度、中央角膜厚度、前房深度、晶状体厚度)。结果:治疗1a后观察组裸眼视力(LogMAR)优于对照组(0.51±0.12 vs 0.73±0.15),等效球镜度数(-0.23±0.05 vs-5.32±1.35D)及柱镜度数均小于对照组(-1.53±0.22 vs-1.97±0.35DC)(P<0.001)。治疗1a后两组眼轴长度较治疗前增长且治疗后对照组眼轴更长(25.53±0.84 vs 25.95±0.83mm);治疗后观察组晶状体厚度较治疗前增加(3.39±0.19 vs 3.31±0.15mm)(P<0.05)。治疗1a后观察组调节幅度(14.29±1.37 vs 12.90±1.07D)、调节灵敏度(11.05±2.09 vs 7.59±1.82cpm)、总角膜上皮点染率(15.1%vs 1.9%)均较对照组更高,调节滞后量较对照组更低(0.55±0.11 vs 0.97±0.30D)(P<0.05)。治疗前后两组患者角膜内皮细胞密度(3197.23±249.66 vs 3207.41±258.14cells/mm 2)、角膜内皮细胞面积(309.27±28.04 vs 312.62±24.95mm 2)、并发症发生率(5.7%vs 9.4%),差异均无统计学意义(P>0.05)。结论:夜戴型角膜塑形镜可改善青少年近视患者裸眼视力,降低等效球镜度数及柱镜度数,并可改善调节相关参数且对角膜功能无明显影响。展开更多
文摘Background A prospective 2-night polysomnographic （PSG） study in Chinese snorers was designed to assess the role of the first night effect （FNE） in PSG parameters and the diagnosis of obstructive sleep apnea hypopnea syndrome （OSAHS）.Methods Seventy-two snorers from two teaching hospitals underwent overnight PSG on two consecutive nights. I he night-to-night variability of PSG parameters were recorded and analyzed.Results Sixty-six patients were analyzed. Among all the PSG parameters, only the total time of stage 2 presented a significant difference between two nights： 219.50 （83.50-353.50） vs. 215.25 （59.50-342.50） （P=0.000）. Subgroup assessment showed a slight night-to-night difference in about 1-2 parameters in the group with the apnea-hypopnea index （AHI） -〉20 events per hour as well as the group with AHI 〈20 events per hour, but there was no night-to-night difference in the AHI in each group. And slighter FNE was found among patients -〉40 years old. There was no significant difference in diagnosis of OSAHS. In the decision of severity, a slight difference was found between the two nights with a Kappa value=0.531.Conclusions Only mild FNE can be found on two consecutive nights of PSG in adult Chinese snorers, but it has no effect on the diagnosis of OSAHS. A single polysomnographic night may be adequate for the diagnosis of OSAHS.
文摘目的:比较夜戴型角膜塑形镜与框架眼镜治疗青少年近视效果,为青少年近视治疗方法选择提供参考。方法:前瞻性研究。选择2020-06/11在我院接受治疗的青少年近视患者106例。根据患者意愿将其分为两组:对照组53例在验光后给予常规框架眼镜治疗,观察组53例则给予夜戴型角膜塑形镜治疗。比较两组患者治疗前后裸眼视力(LogMAR)、验光指标(等效球镜度数、柱镜度数)、眼生物学参数(眼轴长度、中央角膜厚度、前房深度、晶状体厚度)。结果:治疗1a后观察组裸眼视力(LogMAR)优于对照组(0.51±0.12 vs 0.73±0.15),等效球镜度数(-0.23±0.05 vs-5.32±1.35D)及柱镜度数均小于对照组(-1.53±0.22 vs-1.97±0.35DC)(P<0.001)。治疗1a后两组眼轴长度较治疗前增长且治疗后对照组眼轴更长(25.53±0.84 vs 25.95±0.83mm);治疗后观察组晶状体厚度较治疗前增加(3.39±0.19 vs 3.31±0.15mm)(P<0.05)。治疗1a后观察组调节幅度(14.29±1.37 vs 12.90±1.07D)、调节灵敏度(11.05±2.09 vs 7.59±1.82cpm)、总角膜上皮点染率(15.1%vs 1.9%)均较对照组更高,调节滞后量较对照组更低(0.55±0.11 vs 0.97±0.30D)(P<0.05)。治疗前后两组患者角膜内皮细胞密度(3197.23±249.66 vs 3207.41±258.14cells/mm 2)、角膜内皮细胞面积(309.27±28.04 vs 312.62±24.95mm 2)、并发症发生率(5.7%vs 9.4%),差异均无统计学意义(P>0.05)。结论:夜戴型角膜塑形镜可改善青少年近视患者裸眼视力,降低等效球镜度数及柱镜度数,并可改善调节相关参数且对角膜功能无明显影响。
