This article studies the fault detection filtering design problem for Roesser type two-dimensional(2-D)nonlinear systems described by uncertain 2-D Takagi-Sugeno(T-S)fuzzy models.Firstly,fuzzy Lyapunov functions are c...This article studies the fault detection filtering design problem for Roesser type two-dimensional(2-D)nonlinear systems described by uncertain 2-D Takagi-Sugeno(T-S)fuzzy models.Firstly,fuzzy Lyapunov functions are constructed and the 2-D Fourier transform is exploited,based on which a finite frequency fault detection filtering design method is proposed such that a residual signal is generated with robustness to external disturbances and sensitivity to faults.It has been shown that the utilization of available frequency spectrum information of faults and disturbances makes the proposed filtering design method more general and less conservative compared with a conventional nonfrequency based filtering design approach.Then,with the proposed evaluation function and its threshold,a novel mixed finite frequency H_(∞)/H_(-)fault detection algorithm is developed,based on which the fault can be immediately detected once the evaluation function exceeds the threshold.Finally,it is verified with simulation studies that the proposed method is effective and less conservative than conventional non-frequency and/or common Lyapunov function based filtering design methods.展开更多
SKINNY-64-64 is a lightweight block cipher with a 64-bit block length and key length,and it is mainly used on the Internet of Things(IoT).Currently,faults can be injected into cryptographic devices by attackers in a v...SKINNY-64-64 is a lightweight block cipher with a 64-bit block length and key length,and it is mainly used on the Internet of Things(IoT).Currently,faults can be injected into cryptographic devices by attackers in a variety of ways,but it is still difficult to achieve a precisely located fault attacks at a low cost,whereas a Hardware Trojan(HT)can realize this.Temperature,as a physical quantity incidental to the operation of a cryptographic device,is easily overlooked.In this paper,a temperature-triggered HT(THT)is designed,which,when activated,causes a specific bit of the intermediate state of the SKINNY-64-64 to be flipped.Further,in this paper,a THT-based algebraic fault analysis(THT-AFA)method is proposed.To demonstrate the effectiveness of the method,experiments on algebraic fault analysis(AFA)and THT-AFA have been carried out on SKINNY-64-64.In the THT-AFA for SKINNY-64-64,it is only required to activate the THT 3 times to obtain the master key with a 100%success rate,and the average time for the attack is 64.57 s.However,when performing AFA on this cipher,we provide a relation-ship between the number of different faults and the residual entropy of the key.In comparison,our proposed THT-AFA method has better performance in terms of attack efficiency.To the best of our knowledge,this is the first HT attack on SKINNY-64-64.展开更多
The great Sanhe-Pinggu M8 earthquake occurred in 1679 was the largest surface rupture event recorded in history in the northern part of North China plain. This study determines the fault geometry of this earthquake by...The great Sanhe-Pinggu M8 earthquake occurred in 1679 was the largest surface rupture event recorded in history in the northern part of North China plain. This study determines the fault geometry of this earthquake by inverting seismological data of present-day moderate-small earthquakes in the focal area. We relocated those earthquakes with the double-difference method. Based on the assumption that clustered small earthquakes often occur in the vicinity of fault plane of large earthquake, and referring to the morphology of the long axis of the isoseismal line obtained by the predecessors, we selected a strip-shaped zone from the relocated earthquake catalog in the period from 1980 to 2009 to invert fault plane parameters of this earthquake. The inversion results are as follows: the strike is 38.23°, the dip angle is 82.54°, the slip angle is -156.08°, the fault length is about 80 km, the lower-boundary depth is about 23 km and the buried depth of upper boundary is about 3 kin. This shows that the seismogenic fault is a NNE-trending normal dip-slip fault, southeast wall downward and northwest wall uplift, with the right-lateral strike-slip component. Moreover, the surface rupture zone, intensity distribution of the earth-quake and seismic-wave velocity profile in the focal area all verified our study result.展开更多
This paper reports internal structures of a wide fault zone at Shenxigou,Dujiangyan,Sichuan province,China,and high-velocity frictional properties of the fault gouge collected near the coseismic slip zone during the 2...This paper reports internal structures of a wide fault zone at Shenxigou,Dujiangyan,Sichuan province,China,and high-velocity frictional properties of the fault gouge collected near the coseismic slip zone during the 2008 Wenchuan earthquake.Vertical offset and horizontal displacement at the trench site were 2.8 m(NW side up)and 4.8 m(right-lateral),respectively.The fault zone formed in Triassic sandstone,siltstone,and shale about 500 m away from the Yingxiu-Beichuan fault,a major fault in the Longmenshan fault system.A trench survey across the coseismic fault,and observations of outcrops and drill cores down to a depth of 57 m revealed that the fault zone consists of fault gouge and fault breccia of about0.5 and 250-300 m in widths,respectively,and that the fault strikes N62°E and dips 68° to NW.Quaternary conglomerates were recovered beneath the fault in the drilling,so that the fault moved at least 55 m along the coseismic slip zone,experiencing about 18 events of similar sizes.The fault core is composed of grayish gouge(GG) and blackish gouge(BG) with very complex slip-zone structures.BG contains low-crystalline graphite of about 30 %.High-velocity friction experiments were conducted at normal stresses of 0.6-2.1 MPa and slip rates of 0.1-2.1 m/s.Both GG and BG exhibit dramatic slip weakening at constant high slip rates that can be described as an exponential decay from peak friction coefficient lpto steadystate friction coefficient lssover a slip-weakening distance Dc.Deformation of GG and BG is characterized by overlapped slip-zone structures and development of sharp slickenside surfaces,respectively.Comparison of our data with those reported for other outcrops indicates that the high-velocity frictional properties of the Longmenshan fault zones are quite uniform and the high-velocity weakening must have promoted dynamic rupture propagation during the Wenchuan earthquake.展开更多
Background:Paraoxonase 1(PON1) is an antioxidant enzyme that protects high-density lipoprotein(HDL) and low-density lipoprotein against oxidation.Limited studies have addressed the influenc of exercise on PON1 ac...Background:Paraoxonase 1(PON1) is an antioxidant enzyme that protects high-density lipoprotein(HDL) and low-density lipoprotein against oxidation.Limited studies have addressed the influenc of exercise on PON1 activity and its relationship with PON1 phenotypes.We investigated relationships between PON1-192 phenotypes,PON1 activity,aerobic exercise,and blood lipid and lipoprotein concentrations in middle-aged women.Methods:An exercise group(n=50) engaging in regular aerobic exercise and a control group(n=41) were selected from a subset of 300 Caucasian women that met the inclusion criteria.Serum PON1,salt-stimulated PON1(SSPON1),and arylesterase(ARE) activities;cholesterol levels and ARE activities of total HDL and HDL subgroups(HDLs)(supernatants obtained by polyethylene glycol);and blood lipid and lipoprotein concentrations were determined by standardized enzymatic methods.PON1-192 QQ(low activity),QR(moderate activity),and RR(high activity) phenotype groups were define using serum SSPON1/ARE activity ratios.The R-carries(RC) phenotype group consisted of the QR and RR groups combined.Results:All lipid and lipoprotein concentrations were greater in the exercise group than in the control group.Regardless of phenotype,no significan differences were observed between the exercise and control groups in terms of serum PON1,SSPON1,or ARE activity associated with HDLs(p〉 0.05),whereas PON1 activities in QQ-phenotyped women in the exercise group were significant y higher than those in the control group(p〈0.01),but not the RC group.A statistically significan interaction between PON1 phenotypes(QQ and RC groups) and exercise(exercise and control groups) on PON1 activity was found.Conclusion:These results showed that a regular aerobic exercise program can improve PON1 activity depending on PON1-192 phenotype,but not on lipid and lipoprotein levels,in middle-aged Turkish women.展开更多
A token-bus-based design method of the distributedfault-tolerant industrial network is presented in this pa-per.The dual-link network is of hot-redundancy.The performance of the network is also discussed.
Objective:To investigate the frequency of-786T>C variant in endothelial nitric oxide synthase(eNOS)gene promoter in Iranian women with recurrent pregnancy loss.Methods:Blood samples were obtained from 100 unrelated...Objective:To investigate the frequency of-786T>C variant in endothelial nitric oxide synthase(eNOS)gene promoter in Iranian women with recurrent pregnancy loss.Methods:Blood samples were obtained from 100 unrelated women affected by recurrent pregnancy loss and 100 unaffected women as the controls.Genomic DNA was extracted and-786T>C polymorphism in eNOS gene promoter was investigated by PCR-RFLP method.Statistical analyses and Hardy-Weinberg equilibrium in the groups of patients and controls were performed by Chi-square test and SPSS standard software(Version 21).Results:The frequency of homozygous TT was 40%in cases and 46%in the control group;the frequency of CC was 7%in cases and 5%in the control group;frequency heterozygote TC was 53%in cases and 49%in the control group.Genotype frequencies between the two groups showed no significant differences(P>0.05).Conclusions:The-786T>C polymorphism is not more frequent in recurrent pregnancy loss in this population.展开更多
As maternal deaths have decreased worldwide, increasing attention has been placed on the study of severe obstetric complications, such as hemorrhage, eclampsia, and obstructed labor, to identify where improvements can...As maternal deaths have decreased worldwide, increasing attention has been placed on the study of severe obstetric complications, such as hemorrhage, eclampsia, and obstructed labor, to identify where improvements can be made in maternal health. The objective of this study was to determine pregnancy complications and prenatal care among women aged 15 - 49 in Oğuzeli, Turkey, and to provide data for prevention in the field. This descriptive, cross-sectional study was conducted between February and May 2013 in Oğuzeli distinct, Turkey. The total women registered to family doctors in Oğuzeli was listed and, 470 women were selected using a stratified and simple random sampling technique. Pregnancy complications were asked for the last pregnancy of each women. Of the women, 23.9% (n = 109) declared that they experienced pregnancy complications during their pregnancies. The most frequent problems were anemia (11.1%) hypertension (3.7%) and diabetes mellitus (2.4%) respectively. Women having chronic diseases before their pregnancy were more likely to have pregnancy complications compared to healthy women (p = 0.005). The mean number of prenatal care among women having pregnancy complications was 5.47 ± 3.57, while it was 3.84 ± 3.00 among healthy women (p = 0.000). Women having chronic diseases should be handled carefully and, pregnancy should be delayed until the chronic disease’s remission. Family planning in primary care is the key measure to archive this. Early diagnosis of hypertension among young women is highly important for the women’s and infants’s health during pregnancy, and for the women’s future heath. During prenatal care, women should be trained about correct eating habits and activity.展开更多
Computational intelligence is one of the most powerful data processing tools to solve complex nonlinear problems, and thus plays a significant role in intelligent fault diagnosis and prediction. However, only few com-...Computational intelligence is one of the most powerful data processing tools to solve complex nonlinear problems, and thus plays a significant role in intelligent fault diagnosis and prediction. However, only few com- prehensive reviews have summarized the ongoing efforts of computational intelligence in machinery condition moni- toring and fault diagnosis. The recent research and devel- opment of computational intelligence techniques in fault diagnosis, prediction and optimal sensor placement are reviewed. The advantages and limitations of computational intelligence techniques in practical applications are dis- cussed. The characteristics of different algorithms are compared, and application situations of these methods are summarized. Computational intelligence methods need to be further studied in deep understanding algorithm mech- anism, improving algorithm efficiency and enhancing engineering application. This review may be considered as a useful guidance for researchers in selecting a suit- able method for a specific situation and pointing out potential research directions.展开更多
Based on analysis of newly collected 3D seismic and drilled well data,the geological structure and fault system of Baodao sag have been systematically examined to figure out characteristics of the transition fault ter...Based on analysis of newly collected 3D seismic and drilled well data,the geological structure and fault system of Baodao sag have been systematically examined to figure out characteristics of the transition fault terrace belt and its control on the formation of natural gas reservoirs.The research results show that the Baodao sag has the northern fault terrace belt,central depression belt and southern slope belt developed,among them,the northern fault terrace belt consists of multiple transition fault terrace belts such as Baodao B,A and C from west to east which control the source rocks,traps,reservoirs,oil and gas migration and hydrocarbon enrichment in the Baodao sag.The activity of the main fault of the transition belt in the sedimentary period of Yacheng Formation in the Early Oligocene controlled the hydrocarbon generation kitchen and hydrocarbon generation potential.From west to east,getting closer to the provenance,the transition belt increased in activity strength,thickness of source rock and scale of delta,and had multiple hydrocarbon generation depressions developed.The main fault had local compression under the background of tension and torsion,giving rise to composite traps under the background of large nose structure,and the Baodao A and Baodao C traps to the east are larger than Baodao B trap.Multiple fault terraces controlled the material source input from the uplift area to form large delta sand bodies,and the synthetic transition belt of the west and middle sections and the gentle slope of the east section of the F12 fault in the Baodao A transition belt controlled the input of two major material sources,giving rise to a number of delta lobes in the west and east branches.The large structural ridge formed under the control of the main fault close to the hydrocarbon generation center allows efficient migration and accumulation of oil and gas.The combination mode and active time of the main faults matched well with the natural gas charging period,resulting in the hydrocarbon gas enrichment.Baodao A transition belt is adjacent to Baodao 27,25 and 21 lows,where large braided river delta deposits supplied by Shenhu uplift provenance develop,and it is characterized by large structural ridges allowing high efficient hydrocarbon accumulation,parallel combination of main faults and early cessation of faulting activity,so it is a favorable area for hydrocarbon gas accumulation.Thick high-quality gas reservoirs have been revealed through drilling,leading to the discovery of the first large-scale gas field in Baodo 21-1 of Baodao sag.This discovery also confirms that the north transition zone of Songnan-Baodao sag has good reservoir forming conditions,and the transition fault terrace belt has great exploration potential eastward.展开更多
Quick detection of a small initial fault is important for an induction motor to prevent a consequent large fault.The mathematical model with basic motor equations among voltages,currents,and fluxes is analyzed and the...Quick detection of a small initial fault is important for an induction motor to prevent a consequent large fault.The mathematical model with basic motor equations among voltages,currents,and fluxes is analyzed and the motor model equations are described.The fault related features are extracted.An immune memory dynamic clonal strategy(IMDCS)system is applied to detecting the stator faults of induction motor.Four features are obtained from the induction motor,and then these features are given to the IMDCS system.After the motor condition has been learned by the IMDCS system,the memory set obtained in the training stage can be used to detect any fault.The proposed method is experimentally implemented on the induction motor,and the experimental results show the applicability and effectiveness of the proposed method to the diagnosis of stator winding turn faults in induction motors.展开更多
Background: The main objective of this study is to analyse the change in the type of lesions developed by HPV-infected patients after the introduction of the vaccine in three different periods;2002-2006 (years previou...Background: The main objective of this study is to analyse the change in the type of lesions developed by HPV-infected patients after the introduction of the vaccine in three different periods;2002-2006 (years previous to the implementation of the vaccine in Spain), 2009-2011 (shortly after the vaccination) and 2020-2021 (years where the vaccine was well established) at a single hospital. Methods: This is an observational, descriptive, retrospective study based on the review of the results of the biopsies of patients with HPV lesions at a single large tertiary hospital, Hospital Clínico San Carlos, in Madrid, Spain. We have collected the data from three different time periods: 2002-2006, 2009-2011, 2020-2021 to try to understand the potential changes in these lesions after vaccine introduction. Results: In this time we have reviewed the data from 946 women. In these three periods, a decreasing trend in the rate of squamous cell carcinoma was noted, the rate of adenocarcinoma remains stable, and the rate of cervical intraepithelial neoplasia grades 2 - 3 (CIN 2-3) lesions shows an increasing trend. We have also found a change in the mean ages of the patients with these lesions, as this increased in the three lesions caused by HPV after the implementation of the vaccine. Our study indicates that the identification of other high risk serotypes, apart from 16 and 18, as well as those with indeterminate risk, has undergone a progressive increase, increasing from 24.24% and 14.11% respectively in 2002-2006 to 40.42% and 28.34% in 2020-2021. Conclusion: Our study confirms the effectiveness of the vaccines developed so far, against the HPV serotypes they contain. This is demonstrated by the evidence, in our population, of a decrease in the incidence of squamous cell carcinoma in uterine cervix. In parallel, an increase in the mean age of diagnosis has been verified, for both squamous cell carcinoma and its CIN 2-3 precursor lesions, as well as a change in the infective trend of HPV serotypes that are not included in the current vaccines.展开更多
基金supported in part by the National Natural Science Foundation of China(62373152,62333005,U21B6001,62073143,62273121)in part by the Natural Science Funds for Excellent Young Scholars of Hebei Province in 2022(F2022202014)+1 种基金in part by Science and Technology Research Project of Colleges and Universities in Hebei Province(BJ2020017)in part by the China Postdoctoral Science Foundation(2022M711639,2023T160320).
文摘This article studies the fault detection filtering design problem for Roesser type two-dimensional(2-D)nonlinear systems described by uncertain 2-D Takagi-Sugeno(T-S)fuzzy models.Firstly,fuzzy Lyapunov functions are constructed and the 2-D Fourier transform is exploited,based on which a finite frequency fault detection filtering design method is proposed such that a residual signal is generated with robustness to external disturbances and sensitivity to faults.It has been shown that the utilization of available frequency spectrum information of faults and disturbances makes the proposed filtering design method more general and less conservative compared with a conventional nonfrequency based filtering design approach.Then,with the proposed evaluation function and its threshold,a novel mixed finite frequency H_(∞)/H_(-)fault detection algorithm is developed,based on which the fault can be immediately detected once the evaluation function exceeds the threshold.Finally,it is verified with simulation studies that the proposed method is effective and less conservative than conventional non-frequency and/or common Lyapunov function based filtering design methods.
基金supported in part by the Natural Science Foundation of Heilongjiang Province of China(Grant No.LH2022F053)in part by the Scientific and technological development project of the central government guiding local(Grant No.SBZY2021E076)+2 种基金in part by the PostdoctoralResearch Fund Project of Heilongjiang Province of China(Grant No.LBH-Q21195)in part by the Fundamental Research Funds of Heilongjiang Provincial Universities of China(Grant No.145209146)in part by the National Natural Science Foundation of China(NSFC)(Grant No.61501275).
文摘SKINNY-64-64 is a lightweight block cipher with a 64-bit block length and key length,and it is mainly used on the Internet of Things(IoT).Currently,faults can be injected into cryptographic devices by attackers in a variety of ways,but it is still difficult to achieve a precisely located fault attacks at a low cost,whereas a Hardware Trojan(HT)can realize this.Temperature,as a physical quantity incidental to the operation of a cryptographic device,is easily overlooked.In this paper,a temperature-triggered HT(THT)is designed,which,when activated,causes a specific bit of the intermediate state of the SKINNY-64-64 to be flipped.Further,in this paper,a THT-based algebraic fault analysis(THT-AFA)method is proposed.To demonstrate the effectiveness of the method,experiments on algebraic fault analysis(AFA)and THT-AFA have been carried out on SKINNY-64-64.In the THT-AFA for SKINNY-64-64,it is only required to activate the THT 3 times to obtain the master key with a 100%success rate,and the average time for the attack is 64.57 s.However,when performing AFA on this cipher,we provide a relation-ship between the number of different faults and the residual entropy of the key.In comparison,our proposed THT-AFA method has better performance in terms of attack efficiency.To the best of our knowledge,this is the first HT attack on SKINNY-64-64.
基金jointly supported by the National Natural Science Foundation of China(Nos.91214201 and 41074072)Research Foundation of Science and Technology Plan Project in Hebei Province(12276903D)
文摘The great Sanhe-Pinggu M8 earthquake occurred in 1679 was the largest surface rupture event recorded in history in the northern part of North China plain. This study determines the fault geometry of this earthquake by inverting seismological data of present-day moderate-small earthquakes in the focal area. We relocated those earthquakes with the double-difference method. Based on the assumption that clustered small earthquakes often occur in the vicinity of fault plane of large earthquake, and referring to the morphology of the long axis of the isoseismal line obtained by the predecessors, we selected a strip-shaped zone from the relocated earthquake catalog in the period from 1980 to 2009 to invert fault plane parameters of this earthquake. The inversion results are as follows: the strike is 38.23°, the dip angle is 82.54°, the slip angle is -156.08°, the fault length is about 80 km, the lower-boundary depth is about 23 km and the buried depth of upper boundary is about 3 kin. This shows that the seismogenic fault is a NNE-trending normal dip-slip fault, southeast wall downward and northwest wall uplift, with the right-lateral strike-slip component. Moreover, the surface rupture zone, intensity distribution of the earth-quake and seismic-wave velocity profile in the focal area all verified our study result.
基金supported by State Key Laboratory of Earthquake Dynamics (project No.LED2010A03)Wenchuan Earthquake Fault Scientific Drilling Project (WFSD-09)
文摘This paper reports internal structures of a wide fault zone at Shenxigou,Dujiangyan,Sichuan province,China,and high-velocity frictional properties of the fault gouge collected near the coseismic slip zone during the 2008 Wenchuan earthquake.Vertical offset and horizontal displacement at the trench site were 2.8 m(NW side up)and 4.8 m(right-lateral),respectively.The fault zone formed in Triassic sandstone,siltstone,and shale about 500 m away from the Yingxiu-Beichuan fault,a major fault in the Longmenshan fault system.A trench survey across the coseismic fault,and observations of outcrops and drill cores down to a depth of 57 m revealed that the fault zone consists of fault gouge and fault breccia of about0.5 and 250-300 m in widths,respectively,and that the fault strikes N62°E and dips 68° to NW.Quaternary conglomerates were recovered beneath the fault in the drilling,so that the fault moved at least 55 m along the coseismic slip zone,experiencing about 18 events of similar sizes.The fault core is composed of grayish gouge(GG) and blackish gouge(BG) with very complex slip-zone structures.BG contains low-crystalline graphite of about 30 %.High-velocity friction experiments were conducted at normal stresses of 0.6-2.1 MPa and slip rates of 0.1-2.1 m/s.Both GG and BG exhibit dramatic slip weakening at constant high slip rates that can be described as an exponential decay from peak friction coefficient lpto steadystate friction coefficient lssover a slip-weakening distance Dc.Deformation of GG and BG is characterized by overlapped slip-zone structures and development of sharp slickenside surfaces,respectively.Comparison of our data with those reported for other outcrops indicates that the high-velocity frictional properties of the Longmenshan fault zones are quite uniform and the high-velocity weakening must have promoted dynamic rupture propagation during the Wenchuan earthquake.
基金supported by the Ege University Scientifi Research Projects Directorate(2006-BESYO-004)
文摘Background:Paraoxonase 1(PON1) is an antioxidant enzyme that protects high-density lipoprotein(HDL) and low-density lipoprotein against oxidation.Limited studies have addressed the influenc of exercise on PON1 activity and its relationship with PON1 phenotypes.We investigated relationships between PON1-192 phenotypes,PON1 activity,aerobic exercise,and blood lipid and lipoprotein concentrations in middle-aged women.Methods:An exercise group(n=50) engaging in regular aerobic exercise and a control group(n=41) were selected from a subset of 300 Caucasian women that met the inclusion criteria.Serum PON1,salt-stimulated PON1(SSPON1),and arylesterase(ARE) activities;cholesterol levels and ARE activities of total HDL and HDL subgroups(HDLs)(supernatants obtained by polyethylene glycol);and blood lipid and lipoprotein concentrations were determined by standardized enzymatic methods.PON1-192 QQ(low activity),QR(moderate activity),and RR(high activity) phenotype groups were define using serum SSPON1/ARE activity ratios.The R-carries(RC) phenotype group consisted of the QR and RR groups combined.Results:All lipid and lipoprotein concentrations were greater in the exercise group than in the control group.Regardless of phenotype,no significan differences were observed between the exercise and control groups in terms of serum PON1,SSPON1,or ARE activity associated with HDLs(p〉 0.05),whereas PON1 activities in QQ-phenotyped women in the exercise group were significant y higher than those in the control group(p〈0.01),but not the RC group.A statistically significan interaction between PON1 phenotypes(QQ and RC groups) and exercise(exercise and control groups) on PON1 activity was found.Conclusion:These results showed that a regular aerobic exercise program can improve PON1 activity depending on PON1-192 phenotype,but not on lipid and lipoprotein levels,in middle-aged Turkish women.
文摘A token-bus-based design method of the distributedfault-tolerant industrial network is presented in this pa-per.The dual-link network is of hot-redundancy.The performance of the network is also discussed.
文摘Objective:To investigate the frequency of-786T>C variant in endothelial nitric oxide synthase(eNOS)gene promoter in Iranian women with recurrent pregnancy loss.Methods:Blood samples were obtained from 100 unrelated women affected by recurrent pregnancy loss and 100 unaffected women as the controls.Genomic DNA was extracted and-786T>C polymorphism in eNOS gene promoter was investigated by PCR-RFLP method.Statistical analyses and Hardy-Weinberg equilibrium in the groups of patients and controls were performed by Chi-square test and SPSS standard software(Version 21).Results:The frequency of homozygous TT was 40%in cases and 46%in the control group;the frequency of CC was 7%in cases and 5%in the control group;frequency heterozygote TC was 53%in cases and 49%in the control group.Genotype frequencies between the two groups showed no significant differences(P>0.05).Conclusions:The-786T>C polymorphism is not more frequent in recurrent pregnancy loss in this population.
文摘As maternal deaths have decreased worldwide, increasing attention has been placed on the study of severe obstetric complications, such as hemorrhage, eclampsia, and obstructed labor, to identify where improvements can be made in maternal health. The objective of this study was to determine pregnancy complications and prenatal care among women aged 15 - 49 in Oğuzeli, Turkey, and to provide data for prevention in the field. This descriptive, cross-sectional study was conducted between February and May 2013 in Oğuzeli distinct, Turkey. The total women registered to family doctors in Oğuzeli was listed and, 470 women were selected using a stratified and simple random sampling technique. Pregnancy complications were asked for the last pregnancy of each women. Of the women, 23.9% (n = 109) declared that they experienced pregnancy complications during their pregnancies. The most frequent problems were anemia (11.1%) hypertension (3.7%) and diabetes mellitus (2.4%) respectively. Women having chronic diseases before their pregnancy were more likely to have pregnancy complications compared to healthy women (p = 0.005). The mean number of prenatal care among women having pregnancy complications was 5.47 ± 3.57, while it was 3.84 ± 3.00 among healthy women (p = 0.000). Women having chronic diseases should be handled carefully and, pregnancy should be delayed until the chronic disease’s remission. Family planning in primary care is the key measure to archive this. Early diagnosis of hypertension among young women is highly important for the women’s and infants’s health during pregnancy, and for the women’s future heath. During prenatal care, women should be trained about correct eating habits and activity.
基金Supported by National Natural Science Foundation of China(Grant No.51675098)
文摘Computational intelligence is one of the most powerful data processing tools to solve complex nonlinear problems, and thus plays a significant role in intelligent fault diagnosis and prediction. However, only few com- prehensive reviews have summarized the ongoing efforts of computational intelligence in machinery condition moni- toring and fault diagnosis. The recent research and devel- opment of computational intelligence techniques in fault diagnosis, prediction and optimal sensor placement are reviewed. The advantages and limitations of computational intelligence techniques in practical applications are dis- cussed. The characteristics of different algorithms are compared, and application situations of these methods are summarized. Computational intelligence methods need to be further studied in deep understanding algorithm mech- anism, improving algorithm efficiency and enhancing engineering application. This review may be considered as a useful guidance for researchers in selecting a suit- able method for a specific situation and pointing out potential research directions.
基金Supported by the CNOOC Science and Technology Project(KJZH-2021-0003-00,CNOOC-KJ 135 ZDXM 38 ZJ 03 ZJ).
文摘Based on analysis of newly collected 3D seismic and drilled well data,the geological structure and fault system of Baodao sag have been systematically examined to figure out characteristics of the transition fault terrace belt and its control on the formation of natural gas reservoirs.The research results show that the Baodao sag has the northern fault terrace belt,central depression belt and southern slope belt developed,among them,the northern fault terrace belt consists of multiple transition fault terrace belts such as Baodao B,A and C from west to east which control the source rocks,traps,reservoirs,oil and gas migration and hydrocarbon enrichment in the Baodao sag.The activity of the main fault of the transition belt in the sedimentary period of Yacheng Formation in the Early Oligocene controlled the hydrocarbon generation kitchen and hydrocarbon generation potential.From west to east,getting closer to the provenance,the transition belt increased in activity strength,thickness of source rock and scale of delta,and had multiple hydrocarbon generation depressions developed.The main fault had local compression under the background of tension and torsion,giving rise to composite traps under the background of large nose structure,and the Baodao A and Baodao C traps to the east are larger than Baodao B trap.Multiple fault terraces controlled the material source input from the uplift area to form large delta sand bodies,and the synthetic transition belt of the west and middle sections and the gentle slope of the east section of the F12 fault in the Baodao A transition belt controlled the input of two major material sources,giving rise to a number of delta lobes in the west and east branches.The large structural ridge formed under the control of the main fault close to the hydrocarbon generation center allows efficient migration and accumulation of oil and gas.The combination mode and active time of the main faults matched well with the natural gas charging period,resulting in the hydrocarbon gas enrichment.Baodao A transition belt is adjacent to Baodao 27,25 and 21 lows,where large braided river delta deposits supplied by Shenhu uplift provenance develop,and it is characterized by large structural ridges allowing high efficient hydrocarbon accumulation,parallel combination of main faults and early cessation of faulting activity,so it is a favorable area for hydrocarbon gas accumulation.Thick high-quality gas reservoirs have been revealed through drilling,leading to the discovery of the first large-scale gas field in Baodo 21-1 of Baodao sag.This discovery also confirms that the north transition zone of Songnan-Baodao sag has good reservoir forming conditions,and the transition fault terrace belt has great exploration potential eastward.
基金National Natural Science Foundation of China(No.61105114)the Key Technology R&D Program of Jiangsu Province,China(No.BE2010189)
文摘Quick detection of a small initial fault is important for an induction motor to prevent a consequent large fault.The mathematical model with basic motor equations among voltages,currents,and fluxes is analyzed and the motor model equations are described.The fault related features are extracted.An immune memory dynamic clonal strategy(IMDCS)system is applied to detecting the stator faults of induction motor.Four features are obtained from the induction motor,and then these features are given to the IMDCS system.After the motor condition has been learned by the IMDCS system,the memory set obtained in the training stage can be used to detect any fault.The proposed method is experimentally implemented on the induction motor,and the experimental results show the applicability and effectiveness of the proposed method to the diagnosis of stator winding turn faults in induction motors.
文摘Background: The main objective of this study is to analyse the change in the type of lesions developed by HPV-infected patients after the introduction of the vaccine in three different periods;2002-2006 (years previous to the implementation of the vaccine in Spain), 2009-2011 (shortly after the vaccination) and 2020-2021 (years where the vaccine was well established) at a single hospital. Methods: This is an observational, descriptive, retrospective study based on the review of the results of the biopsies of patients with HPV lesions at a single large tertiary hospital, Hospital Clínico San Carlos, in Madrid, Spain. We have collected the data from three different time periods: 2002-2006, 2009-2011, 2020-2021 to try to understand the potential changes in these lesions after vaccine introduction. Results: In this time we have reviewed the data from 946 women. In these three periods, a decreasing trend in the rate of squamous cell carcinoma was noted, the rate of adenocarcinoma remains stable, and the rate of cervical intraepithelial neoplasia grades 2 - 3 (CIN 2-3) lesions shows an increasing trend. We have also found a change in the mean ages of the patients with these lesions, as this increased in the three lesions caused by HPV after the implementation of the vaccine. Our study indicates that the identification of other high risk serotypes, apart from 16 and 18, as well as those with indeterminate risk, has undergone a progressive increase, increasing from 24.24% and 14.11% respectively in 2002-2006 to 40.42% and 28.34% in 2020-2021. Conclusion: Our study confirms the effectiveness of the vaccines developed so far, against the HPV serotypes they contain. This is demonstrated by the evidence, in our population, of a decrease in the incidence of squamous cell carcinoma in uterine cervix. In parallel, an increase in the mean age of diagnosis has been verified, for both squamous cell carcinoma and its CIN 2-3 precursor lesions, as well as a change in the infective trend of HPV serotypes that are not included in the current vaccines.