青少年“理想-现实”自我差异对非自杀性自伤行为的影响:有调节的中介模型

目的:探讨青少年“理想-现实”自我差异对非自杀性自伤行为的影响以及反刍思维和心理弹性在二者中的作用。方法:使用青少年“理想-现实”自我差异量表、青少年心理弹性量表、反刍思维量表以及青少年自我伤害行为问卷对470名中学生进行调查。结果:1青少年“理想-现实”自我差异、反刍思维、非自杀性自伤行为两两显著正相关(r=0.21~0.50,P<0.01),心理弹性与青少年“理想-现实”自我差异、反刍思维、非自杀性自伤行为均呈显著负相关(r=-0.50~-0.28,P<0.01);2青少年“理想-现实”自我差异可显著正向预测非自杀性自伤行为(β=0.19,P<0.001),并且反刍思维在二者之间起完全中介作用,中介效应量为0.16;③心理弹性在中介作用的后半段起调节作用(β=-0.17,P<0.001),即随着心理弹性的提高,反刍思维对青少年非自杀性自伤行为的正向预测作用减弱(心理弹性低分组β=0.43,P<0.001 vs心理弹性高分组β=0.09,P>0.05)。结论:青少年“理想-现实”自我差异不仅可以直接预测非自杀性自伤行为,还可通过反刍思维间接对非自杀性自伤行为产生影响,心理弹性在这一中介作用的后半段起调节作用。

GT-GRA-TOPSIS在雨水调蓄池选址及数量优化中的应用

【目的】为有效减轻极端暴雨天气造成的城市洪涝问题,开展了对城市雨水排水系统(USDS)中雨水调蓄池(SST)的选址及数量优化的研究。【方法】采用博弈论(GT)思想将层次分析法(AHP)获得的主观权重与改进熵值法(IEVM)获得的客观权重组合赋权,并与灰色关联分析(GRA)和逼近理想解排序(TOPSIS)相结合,建立了城市内涝与面源污染风险的定量评估框架。根据各节点的相对接近度确定风险等级,风险较高的节点设置SST,根据积水削减率和总悬浮物(TSS)削减率优化SST的数量。以山西省长治市为例,探讨了该方法在不同降雨重现期时城市内涝和面源污染的控制效果。【结果】GRA-TOPSIS法在5 a和10 a降雨重现期时的综合变异系数分别为0.355和0.361,极值均为0.496,均高于单独GRA或TOPSIS.【结论】GT赋权并耦合GRA-TOPSIS的优化方法采用较少的经济投资可较好地消除城市内涝和面源污染风险,为SST的选址和数量优化提供了新思路。

否定非对合剩余格上BF-理想的BF-平移与BF-扩张理想

进一步研究否定非对合剩余格的双极值模糊理想(简称BF-理想)问题,引入BF-理想的BF-平移、BF-扩张理想和BF-乘积等概念并考察它们的性质特征和相互关系,为进一步揭示否定非对合剩余格的结构特征拓展研究思路.

Pseudoelastic effect in autoparametric non-ideal vibrating system with SMA spring

In this paper a three degrees of freedom autoparametric system with limited power supply is investigated numerically. The system consists of the body, which is hung on a spring and a damper, and two pendulums connected by shape memory alloy （SMA） spring. Shape memory alloys have ability to change their material properties with temperature. A polynomial constitutive model is assumed to describe the behavior of the SMA spring. The non-ideal source of power adds one degree of freedom, so the system has four degrees of freedom. The equations of motion have been solved numerically and pseudoelastic effects associated with the martensitic phase transformation are studied. It is shown that in this type system one mode of vibrations might excite or damp another mode, and that except different kinds of periodic vibrations there may also appear chaotic vibrations. For the identification of the responses of the system＇s various techniques, including chaos techniques such as bifurcation diagrams and time histories, power spectral densities, Poincare maps and exponents of Lyapunov may be used.

Non-linear Maps on Borel Subalgebras of Simple Lie Algebras Preserving Abelin Ideals

Let g be a complex simple Lie algebra of rank ι, b the standard Borel subalgebra. An invertible map on Ь is said to preserve abelian ideals if it maps each abelian ideal to some such ideal of the same dimension. In this article, by using some results of Chevalley groups, the theory of root systems and root space decomposition, the author gives an explicit description on such maps of Ь.

Confinement Effect and Diameter Effect on the Non-ideal Detonation Parameters of Small Charge

An expanding model of the confinement of non-ideal detonation of small charge is established on the basis of the nozzle theory.Making use of the expanding model,the analytic relationship of small charge detonation velocity and the semi-empirical relationship of detonation pressure that both change with charge diameter and confinement condition are established.The detonation velocity and pressure of small charges are calculated and experimentally verified,and the detonation velocity deviation is less than 7% while the detonation pressure deviation is less than 9%.

Investigation of Shock Waves in Non-Ideal Gas under the Action of Magnetic Field

In present paper, certain aspect of shock wave in non-ideal gas, when magnetic field is orthogonal to the trajectories of the gas particles and electrical conductivity is taken to be infinite, is investigated. Considering one-dimensional unsteady non-planer motion, basic equations, its general solution and formation of shock-wave, conservation laws and jumps conditions, variation of area of non-uniform cross section and analytical solution of strong non planer shock is obtained.

Frequency-Concentration Dependence of Optical Activity of a Non-Ideal 1D-Superlattice

In the present work the widths of layers constituting the non-ideal superlattice are much bigger then the characteristic scales of space dispersion. In such a case the contribution of individual layers to gyrotropy can be regarded as independed. Thus the corresponding optical quantities can be expressed through the layers’ gyrotropic characteristics. This approach is applied to calculate the specific rotation angle of plane of polarization of light propagating through a nonideal 1D-superlattice, which varies in composition as well as in layers’ width. We carry out numerical calculation of the frequency dispersion of optical activity of a non-ideal superlattice, which includes impurity layers with point defects.

肥胖儿童non-HDL-C、remnant cholesterol与亚临床动脉粥样硬化的关系

目的:了解non-HDL-C和remnant cholesterol与肥胖儿童亚临床动脉粥样硬化(AS)的关系。方法:根据甘油三酯(TG)水平将65例肥胖儿童(肥胖组)分为I组(TG≥2.3 mmol/L)32例,II组(TG<2.3 mmol/L)33例,与肥胖组儿童性别年龄相匹配的正常体质量儿童30例为III组(对照组)。比较3组儿童血脂指标,对肥胖组各项血脂指标与血浆致动脉粥样硬化指数(AIP)进行相关性分析,肥胖患儿体质指数、血脂指标与颈动脉内径、内膜-中层厚度(c-IMT)、血流参数进行相关性分析。结果:I组、II组的TG、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、non-HDL-C、remnant cholesterol、AIP均较对照组升高,高密度脂蛋白胆固醇(HDL-C)较对照组降低,且I组的remnant cholesterol、AIP均较II组升高。肥胖组儿童AIP与TG、non-HDL-C、remnant cholesterol呈正相关,与HDL-C呈负相关。37例行颈动脉超声检查的肥胖儿童的c-IMT较正常儿童的增厚。结论:non-HDL-C、remnant cholesterol在肥胖儿童亚临床AS中有重要作用,在肥胖儿童血脂异常的治疗中应关注non-HDL-C、remnant cholesterol的变化。

Shenqi Fuzheng injection combined with GP chemotherapy in the treatment of advanced non-small cell lung cancer： a meta-analysis

Objective： To evaluate the clinical efficacy of Shenqi Fuzheng injection combined with gemcitabine plus cisplatin（GP） in the treatment of advanced non-small cell lung cancer （NSCLC）. Methods： we performed a systematicsearch in the electronic databases such as Cochrane Library, Pubmed, Embase, Chinese Journal Full-text Database,Chinese Biomedical Literature Database, Chinese Science and Technology Periodical Full-text Database andWanfang Database up to 30 January 2017. Randomized controlled trials （RCT） of Shenqi Fuzheng Injectioncombined with GP chemotherapy in the treatment of advanced NSCLC were searched, and all the RCTs wereconducted on methodological quality assessment. Data extraction and data analysis were according to standards ofCochrane systematic review. Results： Eight trials were included including a total of 701 patients. Meta-analysisresults： Shenqi Fuzheng injection combined with GP chemotherapy could significantly improve the functionalstatus of patients with NSCLC （OR = 3.44, 95% CI [2.26, 5.25], P 〈 0.0001） and clinical treatment efficacy （OR =（OR = 0.31, 95%CI [0.20, 0.47], P 〈 0.0001. The rate of leukopenia （OR = .31, 95%CI [0.20,0.47], P 〈 0.0001）,thrombocytopenia （OR = 0.58, 95%CI [0.37, 0.91], P = 0.020）, hemoglobin decline （（OR = 0.31, 95%CI [0.16,0.59], P = 0.0004） and incidence of gastrointestinal reactions （OR = 0.58,P 〈 0.05） could be reduced. Conclusion：Shenqi Fuzheng injection combined with GP chemotherapy in the treatment of advanced NSCLC obtainedsignificantly clinical efficacy. The quality of the literature incorporated is low, the conclusion requires high-qualityresearch to further prove.

THE INVISCID AND NON-RESISTIVE LIMIT IN THE CAUCHY PROBLEM FOR 3-D NONHOMOGENEOUS INCOMPRESSIBLE MAGNETO-HYDRODYNAMICS

In this paper,the inviscid and non-resistive limit is justified for the local-in-time solutions to the equations of nonhomogeneous incompressible magneto-hydrodynamics （MHD）in R3.We prove that as the viscosity and resistivity go to zero,the solution of the Cauchy problem for the nonhomogeneous incompressible MHD system converges to the solution of the ideal MHD system.The convergence rate is also obtained simultaneously.

Analysis of Numerical Results in High Temperature Congealment and Chemistry Non-equilibrium Flow Field

Using the air plasma ignition technique, physicochemical process of burning can be accelerated; concentration limit ofretrofires both can be extended; reliability of retrofires and stability of burning can be improved. In this paper, using internalequivalent heat area in place of electric are that created Ohm heat, the flow fields of thermodynamic equilibrium chemistry con-gealment and chemistry non-equilibrium in the plasma generator were simulated. The influences of the inlet prerotation angleof air, the inlet total pressure of air and the airflow compression angle of spray nozzle on the temperature on the surface of elec-

Turbulent Flow Action of Pulp in Wet - Laid Non - Woven Processes

The paper deals with the fluid field of web forming in wet-laid non-woven production.The influence of the turbulent flow on blending fiber and occluded fluid produced in pulp flow has been discussed in theory and practice.The suitable use of the imported velocity of pulp is very important in producing wet-laid products of good quality.

CYFRA 21-1 as an early predictor of first line chemotherapy response in advanced non small cell lung cancer

Objective： In an era of ever evolving, promising new therapies for advanced non small cell lung cancer （NSCLC）, early predictors of response to therapy, are needed. We evaluated early variations in CYFRA 21-1 serum levels of patients with advanced NSCLC receiving first line chemotherapy and correlated the results with objective tumor response. Methods： 29 consecutive, previously untreated, patients of advanced non small cell lung cancer, with measurable disease on CT scan were evaluated. All patients were treated with conventional systemic chemotherapy, although the choice of chemotherapy was left to the discretion of the treating physicians. Serum samples were obtained immediately before the start of 1st and 2nd cycles of chemotherapy. CYFRA 21-1 was measured with an electrochemiluminescense immunoassay on an automatic analyzer （Elecsys 2000; Roche Diagnostics）. Response was evaluated using Response evaluation criteria in solid tumors （RECIST） criteria. Results： 10 patients had partial response, 9 patients had stable disease and 9 had progressive disease. None of the patients had complete response. 21/29 （72%） patients had an elevated baseline value of CYFRA 21-1.62% patients （18/29） had a decrease in CYFRA 21-1 after 1 cycle of chemotherapy. The average reduction in the 2nd reading was irrespective of whether baseline value was normal or not. The average reduction was statistically significant （P = 0.002; 95% CI, from 0.8369 to 3.49464; t test）. 8 out of 10 （80%） patients with partial response had a reduction in their 2nd reading of. CYFRA （P = 0.019; 95% CI, from 0.81965 to 7.20035; t test） which was significant. We also observed that 6/9 （66%） patients whose disease remains stable also had a decrease in their subsequent reading （P = 0.0106; 95% CI, from -0.44942 to 3.82720; t test）, though it was not significant statistically. Although 5 out of 9 （55%） patients, who had an increase in their CYFRA 21-1 level, had progressive disease, but it was not statistically significant （P = 0.537; 95% CI, from -1.20021 to 2.13354; ttest）. 14 out of 19 （73%） who either had partial response or had stable disease, had a reduction in their 2nd value of CYFRA 21-1 and was significant statistically （P = 0.004; 95% CI, from 0.74792 to 3.50208; t test）. We also observed that except for 1 patient, all patients who had a decrease of 42% or more in their subsequent CYFRA 21-1 level, were those who had either responded to chemotherapy or had stable disease （P = 0.001）, which was statistically significant. Conclusion： We can conclude that monitoring of serum marker CYFRA 21-1, early dudng first-line chemotherapy may be a useful prognostic tool for evaluation of early tumor response in patients with advanced NSCLC.

非理想条件下MMC-DVR的Lyapunov控制策略研究

动态电压调节器(DVR)与模块化多电平转换器(MMC)组合的MMC-DVR可用于解决中高电压的动态电压补偿问题。目前MMC-DVR基本采用PID等线性控制方法,而MMC-DVR为非线性系统,因而其控制效果并不能令人满意。为此,提出了针对非理想条件下MMC-DVR系统的非线性李雅普诺夫(Lyapunov)控制方法来解决此问题。首先,建立MMV-DVR的数学建模。接着,设计了非理想条件下正、负序MMC-DVR的Lyapunov控制系统。最后,通过实验验证了所提的Lyapunov控制方法用于MMC-DVR的正确性和有效性。与传统PID控制相比,Lyapunov控制方法的电压在理想、非理想的多种不同工况下都能得到很好的补偿,且系统的动态响应更快、鲁棒性更强。

非理想条件下MMC-PET非线性复合控制策略

由于模块化多电平变流器(modular multilevel converter,MMC)电力电子变压器(power electronic transformer,PET)使用传统的控制策略难以保证系统运行时的动态性能,在电网处于不平衡时使得控制难度进一步增加。为了提高系统的动态性能,提出了一种非线性的反馈线性化滑模复合控制策略。该复合控制策略将反馈线性化控制(feedback linearization control,FLC)和滑模控制(sliding mode control,SMC)的优势结合在一起实现优势互补。首先,建立了MMC-PET整体仿真模型;其次,通过数学模型建立反馈线性化滑模控制的控制模型;最后,利用仿真与实验平台进行仿真对比实验,将所提复合控制策略与单一的反馈线性化控制、滑模控制以及常用的PI控制作了仿真对比,以验证所提控制策略可以在外部扰动时具有良好的动态性能和较好的鲁棒性等优势。

MiR-16-5p plays an inhibitory role in human non-small cell lung cancer through Fermitin family member 2

Increasing evidence indicates that aberrant expressions of some microRNAs are associated with cancer progression.However,the roles and biological mechanisms of miRNA-16-5p in human non-small cell lung cancer(NSCLC)are not to be well studied.Here,we validated that the expression of miR-16-5p was decreased significantly in NSCLC samples and cell lines.The correlation between the clinicopathological features of NSCLC and the miR-16-5p expression showed that the expression of miR-16-5p in non-small cell lung cancer was linked with the advanced TNM stage,positive lymph node metastasis,with short overall survival(OS).Also,a negative correlation between miR-16-5p and Fermitin family member 2(FERMT2)was observed,implying there may be a potential link about their regulation.The hypothesis was further confirmed by in-silico analysis and dual-luciferase reporter assay.Moreover,we demonstrated that the transfections of miR-16-5p mimics could alter some biological characteristics of NSCLC cells remarkably accomplished by the expression variance of FERMT2 in vitro and in vivo assays.Summarily,this study demonstrated that miR-16-5p,as a tumor suppression factor in NSCLC by targeting FERMT2,could serve as one promising biomarker in the prediction for NSCLC patients.

非理想电网下基于双d-q变换的锁相环设计

针对传统的单同步坐标锁相环(SSRF-SPLL)在非理想电网条件下存在检测相位和幅值不准确的问题,此处提出多陷波器级联的双同步坐标系解耦软件锁相环(DDSRF-SPLL),通过多个陷波器级联环节滤除电网背景谐波,通过双同步坐标系解耦滤波环节提取电网正负序分量。该方案可以快速准确地输出电网电压的相位、频率和正负序分量。仿真和实验结果验证了所提锁相环(PLL)在电压理想工况、不平衡工况、基波非工频工况和电压有背景谐波工况的有效性。

The Non-Smooth Problem of Wheel Motion

Planar motion of a non-deformable wheel under the action of non-ideal unilateral constraints is considered. The mathematical description of this phenomenon has a form of a non-smooth initial value problem. The non-smoothness of this problem means that its solution is determined by an absolutely continuous function having a discontinuous first derivative. For this reason, a collision problem describing abrupt changes of velocity has been formulated next to the equations of motion specifying the acceleration. The non-idealness of constraints means that the constraint reaction force includes also a component resulting from the friction between the wheel and the constraints. Differential equations specifying acceleration of the wheel making contact with the constraints and algebraic equations for determining the changes in the wheel’s velocity at the moment of collision have been formulated in the paper. The principal task in these formulations is to determine the reaction forces of the considered constraints. This task is specified by the relationships between acceleration and the constraint reaction force components. In the description of the collision, these relations refer to the post-collision velocities and reaction force impulses. For determining an approximate solution of the formulated wheel motion problem, an original numerical method and a computer program for wheel motion simulation have been developed. Selected results illustrating the changes in displacements and velocity have been presented.

非理想电网电压下MMC-UPQC的PBC-SMC控制策略研究

针对非理想电网电压时模块化多电平换流器(MMC)和统一电能质量控制器(UPQC)组合而成的MMC-UPQC,采用单一的PID控制、无源性控制(PBC)、滑模控制(SMC)的电能质量不够理想问题,提出了PBC与SMC组合的无源性滑模控制(PBC-SMC)策略来提高电能质量。首先,推导出电网电压不平衡时MMC-UPQC的总体数学模型,并对电压与电流进行正序与负序分离;然后,针对当前单一的控制方法的补偿效果存在的问题,提出了MMC-UPQC的PBC-SMC控制策略来提高电压电流电能质量;最后,通过MATLAB/Simulink仿真验证了所提控制策略的正确性和可行性,基于PBC-SMC控制的MMC-UPQC系统能够很好地补偿电压电流,提升电能质量,且相比于PID和PBC控制,还有抗扰性更强、精确度更高、响应更快特点。