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肥胖儿童non-HDL-C、remnant cholesterol与亚临床动脉粥样硬化的关系 被引量:4
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作者 焦朝艳 刘戈力 +4 位作者 鲍鹏丽 魏莹 杨箐岩 郑荣秀 赵菁 《天津医科大学学报》 2014年第1期25-28,共4页
目的:了解non-HDL-C和remnant cholesterol与肥胖儿童亚临床动脉粥样硬化(AS)的关系。方法:根据甘油三酯(TG)水平将65例肥胖儿童(肥胖组)分为I组(TG≥2.3 mmol/L)32例,II组(TG<2.3 mmol/L)33例,与肥胖组儿童性别年龄相匹配的正常体... 目的:了解non-HDL-C和remnant cholesterol与肥胖儿童亚临床动脉粥样硬化(AS)的关系。方法:根据甘油三酯(TG)水平将65例肥胖儿童(肥胖组)分为I组(TG≥2.3 mmol/L)32例,II组(TG<2.3 mmol/L)33例,与肥胖组儿童性别年龄相匹配的正常体质量儿童30例为III组(对照组)。比较3组儿童血脂指标,对肥胖组各项血脂指标与血浆致动脉粥样硬化指数(AIP)进行相关性分析,肥胖患儿体质指数、血脂指标与颈动脉内径、内膜-中层厚度(c-IMT)、血流参数进行相关性分析。结果:I组、II组的TG、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、non-HDL-C、remnant cholesterol、AIP均较对照组升高,高密度脂蛋白胆固醇(HDL-C)较对照组降低,且I组的remnant cholesterol、AIP均较II组升高。肥胖组儿童AIP与TG、non-HDL-C、remnant cholesterol呈正相关,与HDL-C呈负相关。37例行颈动脉超声检查的肥胖儿童的c-IMT较正常儿童的增厚。结论:non-HDL-C、remnant cholesterol在肥胖儿童亚临床AS中有重要作用,在肥胖儿童血脂异常的治疗中应关注non-HDL-C、remnant cholesterol的变化。 展开更多
关键词 儿童肥胖 亚临床动脉粥样硬化 non—HDL—C REMNANT CHOLESTEROL 血浆致动脉粥样硬化指数 颈动脉内膜-中层厚度
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Shenqi Fuzheng injection combined with GP chemotherapy in the treatment of advanced non-small cell lung cancer: a meta-analysis 被引量:13
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作者 Qiang Zhang Yi-Huan Fan +2 位作者 Teng Zhang Xiao-Lan Qin Ji-Fang Song 《TMR Integrative Medicine》 2017年第2期68-78,共11页
Objective: To evaluate the clinical efficacy of Shenqi Fuzheng injection combined with gemcitabine plus cisplatin(GP) in the treatment of advanced non-small cell lung cancer (NSCLC). Methods: we performed a syst... Objective: To evaluate the clinical efficacy of Shenqi Fuzheng injection combined with gemcitabine plus cisplatin(GP) in the treatment of advanced non-small cell lung cancer (NSCLC). Methods: we performed a systematicsearch in the electronic databases such as Cochrane Library, Pubmed, Embase, Chinese Journal Full-text Database,Chinese Biomedical Literature Database, Chinese Science and Technology Periodical Full-text Database andWanfang Database up to 30 January 2017. Randomized controlled trials (RCT) of Shenqi Fuzheng Injectioncombined with GP chemotherapy in the treatment of advanced NSCLC were searched, and all the RCTs wereconducted on methodological quality assessment. Data extraction and data analysis were according to standards ofCochrane systematic review. Results: Eight trials were included including a total of 701 patients. Meta-analysisresults: Shenqi Fuzheng injection combined with GP chemotherapy could significantly improve the functionalstatus of patients with NSCLC (OR = 3.44, 95% CI [2.26, 5.25], P 〈 0.0001) and clinical treatment efficacy (OR =(OR = 0.31, 95%CI [0.20, 0.47], P 〈 0.0001. The rate of leukopenia (OR = .31, 95%CI [0.20,0.47], P 〈 0.0001),thrombocytopenia (OR = 0.58, 95%CI [0.37, 0.91], P = 0.020), hemoglobin decline ((OR = 0.31, 95%CI [0.16,0.59], P = 0.0004) and incidence of gastrointestinal reactions (OR = 0.58,P 〈 0.05) could be reduced. Conclusion:Shenqi Fuzheng injection combined with GP chemotherapy in the treatment of advanced NSCLC obtainedsignificantly clinical efficacy. The quality of the literature incorporated is low, the conclusion requires high-qualityresearch to further prove. 展开更多
关键词 Shenqi Fuzheng GP chemotherapy Advanced non - small cell lung cancer Meta analysis
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Analysis of Numerical Results in High Temperature Congealment and Chemistry Non-equilibrium Flow Field
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作者 Hong-tao Zheng Zhi-yong Tan +2 位作者 Hai-ou Sun Chun-liang Zhou Zhi-ming Li 《Journal of Marine Science and Application》 2002年第1期26-34,共9页
Using the air plasma ignition technique, physicochemical process of burning can be accelerated; concentration limit ofretrofires both can be extended; reliability of retrofires and stability of burning can be improved... Using the air plasma ignition technique, physicochemical process of burning can be accelerated; concentration limit ofretrofires both can be extended; reliability of retrofires and stability of burning can be improved. In this paper, using internalequivalent heat area in place of electric are that created Ohm heat, the flow fields of thermodynamic equilibrium chemistry con-gealment and chemistry non-equilibrium in the plasma generator were simulated. The influences of the inlet prerotation angleof air, the inlet total pressure of air and the airflow compression angle of spray nozzle on the temperature on the surface of elec- 展开更多
关键词 plasma GENERATOR CHEMISTRY non - EQUILIBRIUM IGNITION technique numerical calculation
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Turbulent Flow Action of Pulp in Wet - Laid Non - Woven Processes
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作者 程隆棣 黄秀宝 于修业 《Journal of China Textile University(English Edition)》 EI CAS 2000年第3期57-59,共3页
The paper deals with the fluid field of web forming in wet-laid non-woven production.The influence of the turbulent flow on blending fiber and occluded fluid produced in pulp flow has been discussed in theory and prac... The paper deals with the fluid field of web forming in wet-laid non-woven production.The influence of the turbulent flow on blending fiber and occluded fluid produced in pulp flow has been discussed in theory and practice.The suitable use of the imported velocity of pulp is very important in producing wet-laid products of good quality. 展开更多
关键词 WET - laid non - woven fiber PULP FLOW TURBULENT FLOW layer FLUID occluded FLUID .
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CYFRA 21-1 as an early predictor of first line chemotherapy response in advanced non small cell lung cancer
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作者 Kashif Iqbal 《The Chinese-German Journal of Clinical Oncology》 CAS 2007年第3期250-253,共4页
Objective: In an era of ever evolving, promising new therapies for advanced non small cell lung cancer (NSCLC), early predictors of response to therapy, are needed. We evaluated early variations in CYFRA 21-1 serum... Objective: In an era of ever evolving, promising new therapies for advanced non small cell lung cancer (NSCLC), early predictors of response to therapy, are needed. We evaluated early variations in CYFRA 21-1 serum levels of patients with advanced NSCLC receiving first line chemotherapy and correlated the results with objective tumor response. Methods: 29 consecutive, previously untreated, patients of advanced non small cell lung cancer, with measurable disease on CT scan were evaluated. All patients were treated with conventional systemic chemotherapy, although the choice of chemotherapy was left to the discretion of the treating physicians. Serum samples were obtained immediately before the start of 1st and 2nd cycles of chemotherapy. CYFRA 21-1 was measured with an electrochemiluminescense immunoassay on an automatic analyzer (Elecsys 2000; Roche Diagnostics). Response was evaluated using Response evaluation criteria in solid tumors (RECIST) criteria. Results: 10 patients had partial response, 9 patients had stable disease and 9 had progressive disease. None of the patients had complete response. 21/29 (72%) patients had an elevated baseline value of CYFRA 21-1.62% patients (18/29) had a decrease in CYFRA 21-1 after 1 cycle of chemotherapy. The average reduction in the 2nd reading was irrespective of whether baseline value was normal or not. The average reduction was statistically significant (P = 0.002; 95% CI, from 0.8369 to 3.49464; t test). 8 out of 10 (80%) patients with partial response had a reduction in their 2nd reading of. CYFRA (P = 0.019; 95% CI, from 0.81965 to 7.20035; t test) which was significant. We also observed that 6/9 (66%) patients whose disease remains stable also had a decrease in their subsequent reading (P = 0.0106; 95% CI, from -0.44942 to 3.82720; t test), though it was not significant statistically. Although 5 out of 9 (55%) patients, who had an increase in their CYFRA 21-1 level, had progressive disease, but it was not statistically significant (P = 0.537; 95% CI, from -1.20021 to 2.13354; ttest). 14 out of 19 (73%) who either had partial response or had stable disease, had a reduction in their 2nd value of CYFRA 21-1 and was significant statistically (P = 0.004; 95% CI, from 0.74792 to 3.50208; t test). We also observed that except for 1 patient, all patients who had a decrease of 42% or more in their subsequent CYFRA 21-1 level, were those who had either responded to chemotherapy or had stable disease (P = 0.001), which was statistically significant. Conclusion: We can conclude that monitoring of serum marker CYFRA 21-1, early dudng first-line chemotherapy may be a useful prognostic tool for evaluation of early tumor response in patients with advanced NSCLC. 展开更多
关键词 CYFRA 21-1 non small cell lung cancer CHEMOTHERAPY RESPONSE
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MiR-16-5p plays an inhibitory role in human non-small cell lung cancer through Fermitin family member 2
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作者 JUNQI GUO YUN YANG +6 位作者 WEI ZHAO ZHONGHAI YAN XIA YANG YUNFEI YAN RUIMIN HAO JINXIA HU FEI JIAO 《BIOCELL》 SCIE 2021年第3期627-638,共12页
Increasing evidence indicates that aberrant expressions of some microRNAs are associated with cancer progression.However,the roles and biological mechanisms of miRNA-16-5p in human non-small cell lung cancer(NSCLC)are... Increasing evidence indicates that aberrant expressions of some microRNAs are associated with cancer progression.However,the roles and biological mechanisms of miRNA-16-5p in human non-small cell lung cancer(NSCLC)are not to be well studied.Here,we validated that the expression of miR-16-5p was decreased significantly in NSCLC samples and cell lines.The correlation between the clinicopathological features of NSCLC and the miR-16-5p expression showed that the expression of miR-16-5p in non-small cell lung cancer was linked with the advanced TNM stage,positive lymph node metastasis,with short overall survival(OS).Also,a negative correlation between miR-16-5p and Fermitin family member 2(FERMT2)was observed,implying there may be a potential link about their regulation.The hypothesis was further confirmed by in-silico analysis and dual-luciferase reporter assay.Moreover,we demonstrated that the transfections of miR-16-5p mimics could alter some biological characteristics of NSCLC cells remarkably accomplished by the expression variance of FERMT2 in vitro and in vivo assays.Summarily,this study demonstrated that miR-16-5p,as a tumor suppression factor in NSCLC by targeting FERMT2,could serve as one promising biomarker in the prediction for NSCLC patients. 展开更多
关键词 miR-16-5p non–small-cell lung cancer(NSCLC) Fermitin family member 2(FERMT2) APOPTOSIS INVASION Overall survival(OS)
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FAREY SEQUENCE OF NONLINEAR DIFFERENTIAL DYNAMIC SYSTEM IN TWO DIMENSIONS 被引量:1
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作者 H. Q. Jin and S. N. Xu Shenyang Institute of Technology , Shenyang 110015 , China 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 1999年第5期1234-1236,共3页
In this paper , through the discrim ination of Farey sequence in the forced Brusselator withweak coupling , it is proved that there is a topological translation fro m a nonlinear differen tial system ( limit cycle)... In this paper , through the discrim ination of Farey sequence in the forced Brusselator withweak coupling , it is proved that there is a topological translation fro m a nonlinear differen tial system ( limit cycle) to the circle m ap . 展开更多
关键词 non - linearity Farey sequence phase lock CHAOS
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Ways to Overcome Anxiety in the English Listening Class in College (SUN JING-YU KE SU-FEN)
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作者 孙晶玉 柯素芬 《呼伦贝尔学院学报》 1999年第1期74-77,87,共5页
In my ten-yeat experience of tenching English as major in college , I feel that students experience more difficulties in listening lessons than in other lessons. What, then, prevents students from achieving success in... In my ten-yeat experience of tenching English as major in college , I feel that students experience more difficulties in listening lessons than in other lessons. What, then, prevents students from achieving success in the listening class? I suggest that anxiety is one of the major factors, which interferes with students listening comprehension. And I would agree with writers such as Gardner and Horwitz et al. (1991)that anxiety may impede learner’s ability to perform successfully in all aspects of learning a foreign language. I feet it is particularly significant for listening. 展开更多
关键词 LISTENING anxiety creation of non - ANXIETY environment skills and process focus COUNSELLING corner exposure to authentic English
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蒙古国产业结构演进研究 被引量:7
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作者 李晗斌 赵儒煜 《东北亚论坛》 CSSCI 北大核心 2009年第5期31-39,共9页
蒙古自摆脱休克式转型带来的经济负增长以来,经济逐步复苏,进入快速、稳定增长轨道。在此过程中,其产业结构呈现升级趋势,畜牧国家特征正在消退,服务国家特征逐渐增强。但是,由于受经济转型的影响及国际市场的冲击,蒙古国产业结构的演... 蒙古自摆脱休克式转型带来的经济负增长以来,经济逐步复苏,进入快速、稳定增长轨道。在此过程中,其产业结构呈现升级趋势,畜牧国家特征正在消退,服务国家特征逐渐增强。但是,由于受经济转型的影响及国际市场的冲击,蒙古国产业结构的演进异于世界多数国家,呈现特例性、逆工业化、"非自律性"等特征,且产业内部结构不平衡,产业发展的资源环境约束较强。在此次金融危机影响下,蒙古经济快速下滑。因此,在今后的中蒙经济合作中,应在进一步加强中蒙交通运输合作的基础上,增强中国对蒙消费产品的出口,促进中国对蒙产业转移。同时,中蒙环保合作也应予以关注。 展开更多
关键词 蒙古国 经济增长 产业结构演进 逆工业化 "非自律性" 中蒙经济合作 政策建议
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氨基酸与钠离子非共价键相互作用的电喷雾质谱研究 被引量:3
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作者 吴胜明 杨松成 +6 位作者 王杰 王鸿丽 刘炳玉 李爱玲 何昆 魏开华 张学敏 《分析测试学报》 CAS CSCD 北大核心 2004年第z1期66-67,共2页
  实验研究中常常观察到钠离子与一些多肽或蛋白质有较强的非共价键结合能力,这种非共价键相互作用可能与生物的一些功能和活性有关.为了进一步了解这一结合作用,我们应用电喷雾质谱研究了常见的20种氨基酸与钠离子在溶液中的非共价...   实验研究中常常观察到钠离子与一些多肽或蛋白质有较强的非共价键结合能力,这种非共价键相互作用可能与生物的一些功能和活性有关.为了进一步了解这一结合作用,我们应用电喷雾质谱研究了常见的20种氨基酸与钠离子在溶液中的非共价键相互作用.实验研究中发现脯氨酸和苯丙胺酸与钠离子有较强的非共价键结合能力.…… 展开更多
关键词 Sodium ion Amino acids non - covalent interaction ESI - MS
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PROGRESS IN ION BEAM ANALYSIS AT FUDAN UNIVERSITY
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作者 杨福家 汤家镛 《Nuclear Science and Techniques》 SCIE CAS CSCD 1990年第Z1期1-9,共9页
Progres in ion beam analysis at Fudan University in the recent years is briefly reviewed. Presented as examples of the research activities performed in this field are the following projects: (1) Nuclear potential reso... Progres in ion beam analysis at Fudan University in the recent years is briefly reviewed. Presented as examples of the research activities performed in this field are the following projects: (1) Nuclear potential resonance scattering of 6.25 MeV and 4.25 MeV helium ions for simultaneous compositional analysis of carbon and oxygen in a Mylar, a SnInO, and some other film samples: (2) Determination of stoichiometry of a high-temperature superconducting Y-Ba-Cu-O sample by backscattering of 8.8 MeV helium ions; (3) Backscattering and channeling analysis of multilayered structures periodically consisting of layers of pure Si and alternate layers of Ge and Si, grown on (100) Si substrates by molecular beam epitaxy: (4) Studies of surface structure of Al(100) by the use of MeV ions backscattering and channeling surface peak: and (5) MeV ion microbeam analysis and the use of PIXE method in DNA study. etc. 展开更多
关键词 ION beam ANALYSIS non - RUTHERFORD BACKSCATTERING CHANNELING ANALYSIS of superlattice Surface structure study MeV ION MICROBEAM system
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Optically Powered Temperature Measuring Instrument for Big Rotor
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作者 ZHENG Dezhong(Yanshan University, Qinhuandao 066004, CHN) 《Semiconductor Photonics and Technology》 CAS 1997年第1期35-39,共5页
Abstract: A micro - power consumption non - contact temperature measuring instrument for big rotor is introduced. As it solves very well the signal coupling under high speed rotation and power supply problem for probe... Abstract: A micro - power consumption non - contact temperature measuring instrument for big rotor is introduced. As it solves very well the signal coupling under high speed rotation and power supply problem for probe, the instrument can realize persistent on - line temperature measurement for big rotor drived by the ordinary light transmitted by optical fiber under the room light. 展开更多
关键词 non - contact Measurement Optical Fiber ROTOR SemiconductorThermistor
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Heat Production Rate Calculation of Thermal Manikin with a Compensation Method
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作者 朱利军 张渭源 +1 位作者 陈文飞 陈景山 《Journal of China Textile University(English Edition)》 EI CAS 2000年第1期79-81,共3页
Thermal manikin plays important roles in simulating thethermal state of human bodies to facilitate the evaluationof thermal comfort properties of various clothing assem-blies.Based on the heat balance principle and an... Thermal manikin plays important roles in simulating thethermal state of human bodies to facilitate the evaluationof thermal comfort properties of various clothing assem-blies.Based on the heat balance principle and analysis ofrelated factors,the heat production rate of manikin isrecommended as an efficient evaluation index.Whereas,its inside heat production which occurs as a result of theexistence of temperature difference between its insidepart and outside surface,should not be ignored.Through a series of theoretical analysis and calculations,a compensative equation is deduced in this paper. 展开更多
关键词 thermal MANIKIN HEAT balance non - evapora-tive HEAT loss HEAT PRODUCTION RATE INNER HEAT PRODUCTION RATE CALCULATION compensation.
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EFFECT OF STRUCTURE PARAMETERS OF POLYESTER ON ITS ALKALI REACTION RATE
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作者 武谦 《苏州大学学报(工科版)》 CAS 1993年第S2期45-53,共9页
The effect of the supermoleclar structure of polyester on the effective alkali hy-drolysisis rate constant k has been investigated in the paper.That the average non-crvstal line volume around per crystal grain has a c... The effect of the supermoleclar structure of polyester on the effective alkali hy-drolysisis rate constant k has been investigated in the paper.That the average non-crvstal line volume around per crystal grain has a close relation to the k is proved byexperiments.A simple and effctive method for assessing what effect of the super-molecular structure on the k by its CDT value( Critical Dissolution Time) has beenput forward. 展开更多
关键词 Supermolecutar structure . CRYSTALLINITY CDT Value non - crystal volume. ALKALI HYDROLYSIS rate CON -stant.
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Some Problems Concerning Geologic Structure with Double Layers in Urban Underground Lifeline Engineering
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作者 Peng Yimin Sun JinzhongChina University of Geosciences , Beijing 100083 《Journal of Earth Science》 SCIE CAS CSCD 1991年第1期120-125,共6页
Underground lifeline engineering (ULE for short) in modern city demands the appreciation of an active fault in buried bedrock . Generally speaking , a large number of urban geological textures of a basement may all be... Underground lifeline engineering (ULE for short) in modern city demands the appreciation of an active fault in buried bedrock . Generally speaking , a large number of urban geological textures of a basement may all be simplified into a dual geological texture model , i. e., the upper part of the basement consists of loose covering layer and the lower part consists of bedrock . The study of an active fault should include three parts of contents , i . e ., to determine the lower time limit of activity of the fault , and the time limit must be recognized by both of designing engineers and geologists ; on the basis of the studies of repetition periods of earthquake occurrence to deter mine whether the fault moves or not during the allowed time of efficacy of buildings and constructions ; for the sake of engineering practice , the active rate of the fault must be given . The fault with different active mechanism has different effects on the ULE . The authors studied the effect of lateral non-uniform overburden site on the ULE by means of the supersonic earthquake modelling . Owing to the lateral non - uniformity of the covering sediments , there occurs an obvious jump of amplitude of the seismic wave propagation near the contact surface between two different sedi ments . In addition , from the modelling experiment curves it may be seen that the different focus mechanisms and different medium characters may also exert an effect in different degrees . 展开更多
关键词 underground lifeline engineering dual geological texture overlying layer active fault faulting mechanism supersonic seismic modelling experiment later al non - uniformity .
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Substituting Effect of Y in La_(0.5) Ba_(0.5) CoO_3
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作者 刘宜华 张汝贞 +3 位作者 王成建 岳龙强 季刚 梅良模 《Journal of Rare Earths》 SCIE EI CAS CSCD 2003年第3期347-350,共4页
La 0.5- x Y x Ba 0.5 CoO 3 polycrystals were prepared by solid state reaction. The substituting effects of Y for La on the magnetic and transport properties of the materials were studied systematically... La 0.5- x Y x Ba 0.5 CoO 3 polycrystals were prepared by solid state reaction. The substituting effects of Y for La on the magnetic and transport properties of the materials were studied systematically. The results indicate that substitution of Y induces two effects. Firstly, the charge transfer from Y to 3d orbital of Co happens. This causes the molecular magnetic moment to decrease. Secondly, the antiferromagnetic exchange interaction of Co ions appears. When the content of Y is less than or equal to 30%, the non colinear structure of spins in materials is observed. When the content of Y is greater than 30%, the materials transit from predominant ferromagnetic state to predominant antiferromagnetic one. The conductive mechanism for the materials with different content of Y belongs to the variable range hopping conduction of polarons. The resistivity of materials increases sharply with increasing Y content. 展开更多
关键词 La 0.5- x Y x Ba 0.5 CoO 3 compound charge transfer non colinear structure of spins variable range hopping conduction rare earths
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