Modified Two-Degrees-of-Freedom Internal Model Control for Non-Square Systems with Multiple Time Delays

A modified two-degrees-of-freedom( M-TDOF) internal model control( IMC) method is proposed for non-square systems with multiple time delays and right-half-plane( RHP) zeros. In this method,pseudo-inverse is introduced to design the internal model controller,and a desired closed-loop transfer function is designed to eliminate the unrealizable factors of the derived controller. In addition,set-point tracking and load-disturbance rejection of each process are separately controlled by two controllers. The simulation results show that in addition to high decoupling performance and robustness,the proposed control method also effectively improves loaddisturbance rejection and simultaneously optimizes the input tracking performance and disturbance rejection performance by selecting the parameters of controllers. Furthermore,the higher tolerance of model mismatch is achieved in this paper.

THE MODULUS OF CONVEXITY AND THE EQUIVALENT CONDITIONS OF UNIFORMLY NON-SQUARE SPACES

This paper shows that X is uniformly non-square iff P(η_o)】0 for someη_o∈(0,2).Thus X is super-reflexive if and only if for X there exists an equivalent normwhich meets the above condition.By virtue of the before mentioned result,the author derives the necessary,and suffi-cient conditions for X and l^p(X_j)being uniformly non-square,respectively,and gives acharacterization of finite-dimensional spaces which are uniformly non-square.

Determination of Roxithromycin Tablets by Capillary Electrophoresis Employing Non-aqueous Media with Square-wave Amperometric Detection

A new method of determination for roxithromycin tablets by non-aqueous capillary electrophoresis (NACE) with square-wave amperometric detection was carried out. Several parameters affecting the NACE-AD determination were studied. The data was modified by spline wavelet least square (SWLS). The method is simple, rapid and highly reliable for routine analysis.

Auto-selection order of Markov chain for background sequences with chi-square test

Modeling non coding background sequences appropriately is important for the detection of regulatory elements from DNA sequences. Based on the chi square statistic test, some explanations about why to choose higher order Markov chain model and how to automatically select the proper order are given in this paper. The chi square test is first run on synthetic data sets to show that it can efficiently find the proper order of Markov chain. Using chi square test, distinct higher order context dependences inherent in ten sets of sequences of yeast S.cerevisiae from other literature have been found. So the Markov chain with higher order would be more suitable for modeling the non coding background sequences than an independent model.

Square-Root Dynamics of a SIR-Model in Fractional Order

In this paper, we consider an SIR-model for which the interaction term is the square root of the susceptible and infected individuals in the form of fractional order differential equations. First the non-negative solution of the model in fractional order is presented. Then the local stability analysis of the model in fractional order is discussed. Finally, the general solutions are presented and a discrete-time finite difference scheme is constructed using the nonstandard finite difference (NSFD) method. A comparative study of the classical Runge-Kutta method and ODE45 is presented in the case of integer order derivatives. The solutions obtained are presented graphically.

A NEW SOLUTION MODEL OF NONLINEAR DYNAMIC LEAST SQUARE ADJUSTMENT

The nonlinear least square adjustment is a head object studied in technology fields. The paper studies on the non derivative solution to the nonlinear dynamic least square adjustment and puts forward a new algorithm model and its solution model. The method has little calculation load and is simple. This opens up a theoretical method to solve the linear dynamic least square adjustment.

Non-Restoring开方算法及FPGA实现

简单介绍了开方运算的Non-Restoring算法,并对该算法的实现问题进行了深入研究。与其他一些算法相比,该算法具有计算过程简单、结果准确等优点。基于特定专用集成电路(ASIC)和VHDL语言,给出了用现场可编程门阵列(FPGA)实现该算法的一种方案。

肥胖儿童non-HDL-C、remnant cholesterol与亚临床动脉粥样硬化的关系

目的:了解non-HDL-C和remnant cholesterol与肥胖儿童亚临床动脉粥样硬化(AS)的关系。方法:根据甘油三酯(TG)水平将65例肥胖儿童(肥胖组)分为I组(TG≥2.3 mmol/L)32例,II组(TG<2.3 mmol/L)33例,与肥胖组儿童性别年龄相匹配的正常体质量儿童30例为III组(对照组)。比较3组儿童血脂指标,对肥胖组各项血脂指标与血浆致动脉粥样硬化指数(AIP)进行相关性分析,肥胖患儿体质指数、血脂指标与颈动脉内径、内膜-中层厚度(c-IMT)、血流参数进行相关性分析。结果:I组、II组的TG、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、non-HDL-C、remnant cholesterol、AIP均较对照组升高,高密度脂蛋白胆固醇(HDL-C)较对照组降低,且I组的remnant cholesterol、AIP均较II组升高。肥胖组儿童AIP与TG、non-HDL-C、remnant cholesterol呈正相关,与HDL-C呈负相关。37例行颈动脉超声检查的肥胖儿童的c-IMT较正常儿童的增厚。结论:non-HDL-C、remnant cholesterol在肥胖儿童亚临床AS中有重要作用,在肥胖儿童血脂异常的治疗中应关注non-HDL-C、remnant cholesterol的变化。

非均匀网络中半径可调的ARDV-Hop定位算法

针对无线传感网络中传统DV-Hop(Distance Vector Hop)定位算法节点分布不均匀导致定位误差较大的问题,提出了非均匀网络中半径可调的ARDV-Hop(Adjustable Radius DV-Hop in Non-uniform Networks)定位算法。该算法通过半径可调的方式对节点间的跳数进行细化,用细化后呈小数级的跳数代替传统的整数级跳数,并建立了数据能量消耗模型,优化了网络传输性能。ARDV-Hop算法还针对节点分布不均匀的区域提出跳距优化算法:在节点密度大的区域,采用余弦定理优化跳距;密度小的区域,采用最小均方误差(Least Mean Square,LMS)来修正跳距。仿真实验表明,在同等网络环境下,与传统DV-Hop算法、GDV-Hop算法和WOA-DV-Hop算法相比,ARDV-Hop算法能更有效地降低定位误差.

Shenqi Fuzheng injection combined with GP chemotherapy in the treatment of advanced non-small cell lung cancer： a meta-analysis

Objective： To evaluate the clinical efficacy of Shenqi Fuzheng injection combined with gemcitabine plus cisplatin（GP） in the treatment of advanced non-small cell lung cancer （NSCLC）. Methods： we performed a systematicsearch in the electronic databases such as Cochrane Library, Pubmed, Embase, Chinese Journal Full-text Database,Chinese Biomedical Literature Database, Chinese Science and Technology Periodical Full-text Database andWanfang Database up to 30 January 2017. Randomized controlled trials （RCT） of Shenqi Fuzheng Injectioncombined with GP chemotherapy in the treatment of advanced NSCLC were searched, and all the RCTs wereconducted on methodological quality assessment. Data extraction and data analysis were according to standards ofCochrane systematic review. Results： Eight trials were included including a total of 701 patients. Meta-analysisresults： Shenqi Fuzheng injection combined with GP chemotherapy could significantly improve the functionalstatus of patients with NSCLC （OR = 3.44, 95% CI [2.26, 5.25], P 〈 0.0001） and clinical treatment efficacy （OR =（OR = 0.31, 95%CI [0.20, 0.47], P 〈 0.0001. The rate of leukopenia （OR = .31, 95%CI [0.20,0.47], P 〈 0.0001）,thrombocytopenia （OR = 0.58, 95%CI [0.37, 0.91], P = 0.020）, hemoglobin decline （（OR = 0.31, 95%CI [0.16,0.59], P = 0.0004） and incidence of gastrointestinal reactions （OR = 0.58,P 〈 0.05） could be reduced. Conclusion：Shenqi Fuzheng injection combined with GP chemotherapy in the treatment of advanced NSCLC obtainedsignificantly clinical efficacy. The quality of the literature incorporated is low, the conclusion requires high-qualityresearch to further prove.

Assessing dynamic response of multispan viscoelastic thin beams under a moving mass via generalized moving least square method

Dynamic response of multispan viscoelastic thin beams subjected to a moving mass is studied by an efficient numerical method in some detail. To this end, the unknown parameters of the problem are discretized in spatial domain using generalized moving least square method （GMLSM） and then, discrete equations of motion based on Lagrange＇s equation are obtained. Maximum deflection and bending moments are considered as the important design parameters. The design parameter spectra in terms of mass weight and velocity of the moving mass are presented for multispan viscoelastic beams as well as various values of relaxation rate and beam span number. A reasonable good agreement is achieved between the results of the proposed solution and those obtained by other researchers. The results indicate that, although the load inertia effects in beams with higher span number would be intensified for higher levels of moving mass velocity, the maximum values of design parameters would increase either. Moreover, the possibility of mass separation is shown to be more critical as the span number of the beam increases. This fact also violates the linear relation between the mass weight of the moving load and the associated design parameters, especially for high moving mass velocities. However, as the relaxation rate of the beam material increases, the load inertia effects as well as the possibility of moving mass separation reduces.

Robust and Non-fragile H_∞ Control for a Class of Uncertain Jump Linear Systems

This paper describes the synthesis of robust and non-fragile H∞ state feedback controllers for a class of uncertain jump linear systems with Markovian jumping parameters and state multiplicative noises. Under the assumption of a complete access to the norm-bounds of the system uncertainties and controller gain variations, sufficient conditions on the existence of robust stochastic stability and γ-disturbance attenuation H∞ property are presented. A key feature of this scheme is that the gain matrices of controller are only based on It, the observed projection of the current regime rt.

Application of Total Least Square Algorithm in Static Decoupling of NGMIMU

The linear coupling of Non-gyro Micro Inertial Measurement Unit (NGMIMU) is akind of system error that affects the accuracy of measurement seriously. In this article, theauthor puts forward a new linear decoupling algorithm which simultaneously considers the error ofstandard input signal and output of accelerators when the coupling parameters are calculated. TheTotal Least Square (TLS) solutions of coupling parameters own the minimum characteristic to theinput and output values. Then these parameters are used to reconstruct the outputs of acceleratorsso as to realize the decoupling. The emulation result show that the ratio of decoupling error isless than 8 percent and verify the feasibility of this algorithm.

Analysis of Numerical Results in High Temperature Congealment and Chemistry Non-equilibrium Flow Field

Using the air plasma ignition technique, physicochemical process of burning can be accelerated; concentration limit ofretrofires both can be extended; reliability of retrofires and stability of burning can be improved. In this paper, using internalequivalent heat area in place of electric are that created Ohm heat, the flow fields of thermodynamic equilibrium chemistry con-gealment and chemistry non-equilibrium in the plasma generator were simulated. The influences of the inlet prerotation angleof air, the inlet total pressure of air and the airflow compression angle of spray nozzle on the temperature on the surface of elec-

A further study on the spreading and directionality of Gaussian array beams in non-Kolmogorov turbulence

It is found that in free space, the curves of the mean-squared beam width may each have a cross point at a certain propagation distance Zc. For Gaussian array beams, the analytical expressions of zc are derived. For the coherent com- bination, Zc is larger than that for the incoherent combination. However, in non-Kolmogorov turbulence, the cross point disappears, and the Gaussian array beams will have the same directionality in terms of the angular spread. Furthermore, a short propagation distance is needed to reach the same directionality when the generalized exponent is equal to 3.108. In particular, it is shown that the condition obtained in previous studies is not necessary for laser beams to have the same directionality in turbulence, which is explained physically. On the other hand, the relative average intensity distributions at the position where the Gaussian array beams have the same mean-squared beam width are also examined.

BOUNDEDNESS OF STEIN'S SQUARE FUNCTIONS ASSOCIATED TO OPERATORS ON HARDY SPACES

Let （X, d,μ） be a metric measure space endowed with a metric d and a nonnegative Borel doubling measure μ. Let L be a second order non-negative self-adjoint operator on L^2（X）. Assume that the semigroup e^-tL generated by L satisfies the Davies-Gaffney estimates. Also, assume that L satisfies Plancherel type estimate. Under these conditions, we show that Stein＇s square function Gδ（L） arising from Bochner-Riesz means associated to L is bounded from the Hardy spaces HL^p（X） to L^p（X） for all 0 〈 p ≤ 1.

Turbulent Flow Action of Pulp in Wet - Laid Non - Woven Processes

The paper deals with the fluid field of web forming in wet-laid non-woven production.The influence of the turbulent flow on blending fiber and occluded fluid produced in pulp flow has been discussed in theory and practice.The suitable use of the imported velocity of pulp is very important in producing wet-laid products of good quality.

CYFRA 21-1 as an early predictor of first line chemotherapy response in advanced non small cell lung cancer

Objective： In an era of ever evolving, promising new therapies for advanced non small cell lung cancer （NSCLC）, early predictors of response to therapy, are needed. We evaluated early variations in CYFRA 21-1 serum levels of patients with advanced NSCLC receiving first line chemotherapy and correlated the results with objective tumor response. Methods： 29 consecutive, previously untreated, patients of advanced non small cell lung cancer, with measurable disease on CT scan were evaluated. All patients were treated with conventional systemic chemotherapy, although the choice of chemotherapy was left to the discretion of the treating physicians. Serum samples were obtained immediately before the start of 1st and 2nd cycles of chemotherapy. CYFRA 21-1 was measured with an electrochemiluminescense immunoassay on an automatic analyzer （Elecsys 2000; Roche Diagnostics）. Response was evaluated using Response evaluation criteria in solid tumors （RECIST） criteria. Results： 10 patients had partial response, 9 patients had stable disease and 9 had progressive disease. None of the patients had complete response. 21/29 （72%） patients had an elevated baseline value of CYFRA 21-1.62% patients （18/29） had a decrease in CYFRA 21-1 after 1 cycle of chemotherapy. The average reduction in the 2nd reading was irrespective of whether baseline value was normal or not. The average reduction was statistically significant （P = 0.002; 95% CI, from 0.8369 to 3.49464; t test）. 8 out of 10 （80%） patients with partial response had a reduction in their 2nd reading of. CYFRA （P = 0.019; 95% CI, from 0.81965 to 7.20035; t test） which was significant. We also observed that 6/9 （66%） patients whose disease remains stable also had a decrease in their subsequent reading （P = 0.0106; 95% CI, from -0.44942 to 3.82720; t test）, though it was not significant statistically. Although 5 out of 9 （55%） patients, who had an increase in their CYFRA 21-1 level, had progressive disease, but it was not statistically significant （P = 0.537; 95% CI, from -1.20021 to 2.13354; ttest）. 14 out of 19 （73%） who either had partial response or had stable disease, had a reduction in their 2nd value of CYFRA 21-1 and was significant statistically （P = 0.004; 95% CI, from 0.74792 to 3.50208; t test）. We also observed that except for 1 patient, all patients who had a decrease of 42% or more in their subsequent CYFRA 21-1 level, were those who had either responded to chemotherapy or had stable disease （P = 0.001）, which was statistically significant. Conclusion： We can conclude that monitoring of serum marker CYFRA 21-1, early dudng first-line chemotherapy may be a useful prognostic tool for evaluation of early tumor response in patients with advanced NSCLC.

MiR-16-5p plays an inhibitory role in human non-small cell lung cancer through Fermitin family member 2

Increasing evidence indicates that aberrant expressions of some microRNAs are associated with cancer progression.However,the roles and biological mechanisms of miRNA-16-5p in human non-small cell lung cancer(NSCLC)are not to be well studied.Here,we validated that the expression of miR-16-5p was decreased significantly in NSCLC samples and cell lines.The correlation between the clinicopathological features of NSCLC and the miR-16-5p expression showed that the expression of miR-16-5p in non-small cell lung cancer was linked with the advanced TNM stage,positive lymph node metastasis,with short overall survival(OS).Also,a negative correlation between miR-16-5p and Fermitin family member 2(FERMT2)was observed,implying there may be a potential link about their regulation.The hypothesis was further confirmed by in-silico analysis and dual-luciferase reporter assay.Moreover,we demonstrated that the transfections of miR-16-5p mimics could alter some biological characteristics of NSCLC cells remarkably accomplished by the expression variance of FERMT2 in vitro and in vivo assays.Summarily,this study demonstrated that miR-16-5p,as a tumor suppression factor in NSCLC by targeting FERMT2,could serve as one promising biomarker in the prediction for NSCLC patients.

ON EXPONENTIAL STABILITY OF NON-AUTONOMOUS STOCHASTIC SEMILINEAR EVOLUTION EQUATIONS

Sufficient conditions for the exponential stability of a class of nonlinear, non-autonomous stochastic differential equations in infinite dimensions are studied. The analysis consists of introducing a suitable approximating solution systems and usig a limiting argument to pass on stability of strong solutions to mild ones. Consequently, under these conditions the random attractors of given stochastic systems are reduced to zero with exponential decay. Lastly, two examples are investigated to illustrate the theory.