More and more studies have been reported on whether music and other types of auditory stimulation would improve the quality of sleep. Many of these studies have found significant results, but others argue that music i...More and more studies have been reported on whether music and other types of auditory stimulation would improve the quality of sleep. Many of these studies have found significant results, but others argue that music is not significantly better than the tones or control conditions in improving sleep. For further understanding the relationship between music and sleep or music and arousal, the present study therefore examines the effects of brain music on sleep and arousal by means of biofeedback. The music is from the transformation of rapid eye movement （REM） sleep electroencephalogram （EEG） of rats using an algorithm in the Chengdu Brain Music （CBM） system. When the brain music was played back to rats, EEG data were recorded to assess the efficacy of music to induce or improve sleep, or increase arousal levels by sleep staging, etc. Our results demonstrate that exposure to the brain music increases arousal levels and decreases sleep in rats, and the underlying mechanism of decreased non-rapid eye movement （NREM） and REM sleep may be different.展开更多
目的通过分析快动眼期睡眠行为异常(idiopathic REM sleep disorder,iRBD)患者是否存在嗅觉减退、睡眠障碍、焦虑抑郁,来探讨iRBD患者的非运动障碍特点。方法收集我院2014年1月至2016年1月iRBD患者48例及健康对照组53例,分别对两组人群...目的通过分析快动眼期睡眠行为异常(idiopathic REM sleep disorder,iRBD)患者是否存在嗅觉减退、睡眠障碍、焦虑抑郁,来探讨iRBD患者的非运动障碍特点。方法收集我院2014年1月至2016年1月iRBD患者48例及健康对照组53例,分别对两组人群进行睡眠指标、嗅觉功能、焦虑抑郁量表以及血清中IL-6、TNF-α浓度的检测。结果 iRBD组与健康对照组比较,其总睡眠时间、睡眠效率明显降低(P<0.05);睡眠潜伏期、觉醒指数、快动眼睡眠潜伏期明显增高(P<0.05);嗅觉减退明显增多(P<0.01);焦虑抑郁评分明显增高(P<0.05);但两组人群血清中IL-6及TNF-α浓度差异没有统计学意义(P>0.05)。结论 iRBD与帕金森病有类似的非运动障碍特点,早期干预iRBD人群有利于帕金森病患者的预防和治疗。展开更多
目的 探讨移居不同海拔高原不同时间青年睡眠结构的变化规律及其与高原习服水平之间的关系.方法 前瞻性选择海拔1 400 rn某部无高原暴露史的拟驻防官兵,进驻高原前进行健康体检,排除有睡眠障碍及心肺疾患等不宜进入高原者,最终纳入50名...目的 探讨移居不同海拔高原不同时间青年睡眠结构的变化规律及其与高原习服水平之间的关系.方法 前瞻性选择海拔1 400 rn某部无高原暴露史的拟驻防官兵,进驻高原前进行健康体检,排除有睡眠障碍及心肺疾患等不宜进入高原者,最终纳入50名受试者,均为男性,年龄（20.9±2.0）岁,体重指数（21.5±1.7）kg/m2,随机抽取15名作为平原组进行整夜睡眠监测.在人驻高原3个月和1年后分别在海拔3 700和5 380 m随机抽取10名受试者进行睡眠监测,分别记录海拔3 700 m 3个月组、3 700 m 1年组、5 380 m 3个月组和5 380 m 1年组的睡眠结构变化,并与平原组的睡眠监测结果进行对比.结果 5 380 m 3个月及1年组7h睡眠监测过程中醒觉维持时间较平原组显著延长[（82±60）、（78 ±26）、（47±25） min,P=0.026、0.040].与平原组比较,移居海拔5 380 m 3个月青年睡眠时非快速眼动（NREM）睡眠N1期明显延长,N3期（慢波睡眠期）显著缩短甚至缺如（P＜0.05）,N2期和快速眼动睡眠（REM）期无明显变化（P＞0.05）.与平原组比较,3 700 m 3个月、3 700 m 1年以及5 380 m 1年组睡眠各期比率呈现出一致的变化规律：N2期缩短,REM期延长.结论 平原人对不同海拔高原的习服能力或所需的习服时间不同,习服未完全者睡眠主要表现为N1期延长和N3期缩短,习服较完善后以N2期的缩短和REM期的延长为主.慢波睡眠比率的有效恢复或可作为移居者习服高原低氧环境的一项参考指标.展开更多
基金supported by the National Natural Science Foundation of China under Grant No. 60736029, 30870655, and 30570474.
文摘More and more studies have been reported on whether music and other types of auditory stimulation would improve the quality of sleep. Many of these studies have found significant results, but others argue that music is not significantly better than the tones or control conditions in improving sleep. For further understanding the relationship between music and sleep or music and arousal, the present study therefore examines the effects of brain music on sleep and arousal by means of biofeedback. The music is from the transformation of rapid eye movement （REM） sleep electroencephalogram （EEG） of rats using an algorithm in the Chengdu Brain Music （CBM） system. When the brain music was played back to rats, EEG data were recorded to assess the efficacy of music to induce or improve sleep, or increase arousal levels by sleep staging, etc. Our results demonstrate that exposure to the brain music increases arousal levels and decreases sleep in rats, and the underlying mechanism of decreased non-rapid eye movement （NREM） and REM sleep may be different.
文摘目的 探讨移居不同海拔高原不同时间青年睡眠结构的变化规律及其与高原习服水平之间的关系.方法 前瞻性选择海拔1 400 rn某部无高原暴露史的拟驻防官兵,进驻高原前进行健康体检,排除有睡眠障碍及心肺疾患等不宜进入高原者,最终纳入50名受试者,均为男性,年龄（20.9±2.0）岁,体重指数（21.5±1.7）kg/m2,随机抽取15名作为平原组进行整夜睡眠监测.在人驻高原3个月和1年后分别在海拔3 700和5 380 m随机抽取10名受试者进行睡眠监测,分别记录海拔3 700 m 3个月组、3 700 m 1年组、5 380 m 3个月组和5 380 m 1年组的睡眠结构变化,并与平原组的睡眠监测结果进行对比.结果 5 380 m 3个月及1年组7h睡眠监测过程中醒觉维持时间较平原组显著延长[（82±60）、（78 ±26）、（47±25） min,P=0.026、0.040].与平原组比较,移居海拔5 380 m 3个月青年睡眠时非快速眼动（NREM）睡眠N1期明显延长,N3期（慢波睡眠期）显著缩短甚至缺如（P＜0.05）,N2期和快速眼动睡眠（REM）期无明显变化（P＞0.05）.与平原组比较,3 700 m 3个月、3 700 m 1年以及5 380 m 1年组睡眠各期比率呈现出一致的变化规律：N2期缩短,REM期延长.结论 平原人对不同海拔高原的习服能力或所需的习服时间不同,习服未完全者睡眠主要表现为N1期延长和N3期缩短,习服较完善后以N2期的缩短和REM期的延长为主.慢波睡眠比率的有效恢复或可作为移居者习服高原低氧环境的一项参考指标.
