Efficacy Study on Six Antibiotic Methods for Treating Non-Gonococcal Urethritis and Cervicitis

Objective： To analyze the efficacy of six antibiotic methods for treating non- gonococcal urethritis /cervicitis and the factors influencing efficacy. Methods： Retrospective analysis of 878 nongonococcal urethritis / cervicitis cases which received regular treatment and follow-up in our institute from 1st Jan. 2001 to 31st Aug. 2003. Results： The mean cure rate of six methods for Chlamydia trachamatis （Ct） was 57.116%. There were distinct differences among these methods for Ct treatment.The mean cure rate of six methods for Ureaplasma urealyticum （Uu） was 69.556% and there was no difference among these methods for Uu treatment. Coinfection with Ct and Uu dramatically reduced the elimination rate of these two pathogens. Conclusion： The effectiveness of treatment of these antibodies for non-gonococcal urethritis / cervicitis is not currently satisfactory. Importantly, there were many antibiotic-resistant Ct and Uu strains. The factors influencing antibiotic efficacy and mechanisms need further study.

阿奇霉素、罗红霉素、克拉霉素治疗非淋菌性尿道(宫颈)炎的成本-效果分析

目的:探讨阿奇霉素、罗红霉素、克拉霉素治疗非淋菌性尿道(宫颈)炎(NGU)的成本-效果。方法:采用药物经济学原理对3种治疗方案进行成本-效果分析。结果:阿奇霉素、罗红霉素、克拉霉素治疗非淋菌性尿道(宫颈)炎的有效率分别为72.55%、71.48%、73.16%;成本-效果比(C/E)分别为2.19、2.57和4.24。结论:通过药物经济学的分析,阿奇霉素治疗非淋菌性尿道(宫颈)炎在3种治疗方案中更具成本-效果优势。