RFLP OF HLA CLASS I GENES IN CHINESE POPULATION AND ITS CORRELATION WITH SEROLOGICALLY DEFINED ANTIGEN SPECIFICITIES

The restriction fragnent length polymorphisms （RFLPs） of HLA class I genes in 104 unrelated healthy Chinese individuals were analyzed with Southern blot assay. The DNAs from peripheral blood leucocytes were digested with EcoRI, EcoRV and XbaI respectively, and hybridized with 32P-labeled HLA class I probe （ 1.4Kb, B7 cDNA ）. The results showed that 3 EcoRI fragments （13.7, 8.1 and 5.2 Kb ）, 3 EcoR V fragments （11.3, 7.8 and 4.1 Kb） and 7 Xbal fragmnents （21.9, 19.2, 16.3, 6.0, 3.8, 1.8 and 1.5 Kb） were polymorphic. Ten of the fragments were found to be correlated significantly with the serologically de fined antigen specificities. The significance of this kind of correlation is discussed.

Genetic variants of the class A scavenger receptor gene are associated with coronary artery disease in Chinese

The class A scavenger receptor, encoded by the macrophage scavenger receptor 1 （MSR1） gene, is a pattern recognition receptor （PPR） primarily expressed in macrophages. It has been reported that genetic polymorphisms of MSR1 are significantly associated with the number of diseased vessels and coronary artery narrowing greater than 20% in Caucasians. However, whether it links genetically to coronary artery disease （CAD） in Chinese is not defined. Here, we performed an independent case-control study in a Chinese population consisting of 402 CAD cases and 400 controls by genotyping ten single nucleotide polymorphisms （SNPs） of MSR1. We found that rs416748 and rs13306541 were significantly associated with an increased risk of CAD with per allele odds ratio （OR） of 1.56 [95% confidence interval （CI） = 1.28-1.90; P 〈 0.001] and 1.70 （95% CI = 1.27-2.27; P 〈 0.001）, re- spectively. Our results indicate that genetic variants of MSR1 may serve as predictive markers for the risk of CAD / in combination with traditional risk factors of CAD in Chinese population.

Understanding the PAD-Based Class Acceptance among Modern Chinese College Students’English Learning

This paper gives an understanding of PAD-based class acceptance among modern Chinese college students’English learning.It first introduces the brief definition of what the PAD-based class is,as well as the situation of English language learning in present China,especially the learning amongst Chinese college students.And then it focuses on the acceptance of the PADbased class in the English learning of Chinese college students,including the breakthrough of the traditional Chinese classroom teaching mode and the innovation of the PAD-based class among Chinese college students’English learning.

The Consumption Practices and Identity Formation of the Chinese Middle Class in the Media Era

During the past 40 years following the reform and opening-up policy of 1978,China’s social structure has seen great changes,which include the birth and rapid development of the Chinese middle class as a derivative and consequence of modernization.They are the main source of consumption in contemporary China and display unique characteristics in their consumption practices.Consumption is not only a daily practice,but also a means of demonstrating and forming identity.In this media era,media play an important role in people’s consumption practices and identity formation.In this study,semi-structured interviews were carried out with members of the Chinese middle class to study the relationship between consumption,identity,and media through their oral accounts.Moreover,problems,including the characteristics of middle-class consumption practices and how they use consumption to form identity,were analyzed.This study not only complements studies on the sociology of consumption of the Chinese middle class,but also is of great practical significance for deepening our understanding of the behavioral and ideological characteristics of the Chinese middle class.

Students' In-group Interaction in Chinese ESL Class

The traditional teacher-centered ESL class has been prevalent in China for years. Under this circumstance, teachers tend to adopt a spoon-fed teaching method, and become the dominator in ESL class by setting the same instructional pace, explaining a grammar point, leading drill work; while the students' in-class participation is relatively low. As a result, students with different learning styles often feel suffocated in this teacher-dominated class; they desire to have more opportunities to participate in the free interactions or group discussions.Based on the theoretical framework of interactive teaching approach suggested by Lightbown and Spada(1993),the research aims to analyze the merits of students' in-group interaction and to examine the feasibility of implementing it in Chinese ESL class. The research reveals that in-group interaction can cultivate students' independent learning habits by granting them autonomy to bring about the problem and tackle them. Nonetheless, different perceptions from several students and teachers upon group work may influence the usefulness. The research strives to be instructive for the more efficient application of in-group interaction in Chinese ESL class.

A Study On the Structural Dimension of Middle Class Relational Identification in Chinese Context

Through in-depth interviews,this study makes an exploratory study on the dimension of the middle class relational identification in Chinese context by using the grounded theory.It is mainly composed of 4 dimensions:relational orientation,relational adaptation,relational evaluation and relational development.According to the four dimension model of middle class relational identification,the middle class relational identification in China is the cognitive and behavioral orientation that in the action of achieving a certain purpose,because of the perception of consistence with each other in role cognition and personal cognition,the middle class is willing to unite and trust,respect and understand and coordinate the conflict to adapt to this relationship,and then to form a positive evaluation of the relationship and a sense of belonging and commitment to this relationship.The construction of the structural dimension of middle class relational identification in China is conducive to explaining the endemic phenomena of Chinese middle class.

Analysis of How to Establish a Dialogue-style Class Effectively for the Chinese Interest Course as a Foreign Language

In this paper, I take the Chinese interest class which is very common nowadays as a study subject. According to the characteristics of the Chinese interest course, I analyze how to establish a dialogue-style lesson effectively for the Chinese interest class as a foreign language. Combined with practice, I will propose some difficulties to you for advice while I summarize a number of effective ways that I succeed in my teaching.

An Investigation on Cross-cultural Communication between ForeignTeachers and Chinese Students in College EFL Classes

Nowadays,more and more foreign teachers have come to or been invited to China,joining in the English education cause,especially in colleges and universities.Using the methods of questionnaires and interviews,this paper conducts a survey of three foreign teachers and one hundred Chinese English majors at Qufu Normal University,aiming to explore their different perceptions and attitudes towards varied aspects of cross-cultural communication in native EFL classes.The quantitative and qualitative data obtained from the survey were both processed and analyzed from such categories as "teaching contents","teaching attitude","teaching methods","classroom interaction" and "cultural background".The findings suggested that intercultural communication plays a significant role in the process of English language teaching and learning at college native EFL classes.

Evaluating Chinese College Students' English Compositions:Different Writing Corrective Feedbacks between a Chinese Teacher and a Foreign Teacher & the Attitudes of College Students

The study aims to uncover the differences between a Chinese writing teacher and a foreign writing teacher in evaluating Chinese college students' English compositions and find out students' attitudes towards different kinds of feedbacks. The data collection method, sample analysis and questionnaire have been implemented to probe for the results. The results are supposed to give some suggestions to the English writing class in Chinese universities.

Brief Discussion on Critical Writing and Consciousness-raising Activities for Chinese Students

Current literature has shown support to the combination of Consciousness-raising activity and teacher fronted teaching pedagogy.However,certain contextual analyze was absent in identify the problem in target classroom.In current L2 writing class,there is prevailing problem among Chinese students in acquiring'critical learning'.In this article,the writer tries to find the cause of this problem from students' language input in traditional ESL grammar class,and to identify the cause to problematic critical writing among the target group.The analyze of the problem and the cause of lacking critical consciousness lead to possible solution of applying consciousness raising tasks in traditional writing class in China.

一种新的中文文本分类算法——One Class SVM-KNN算法

中文文本分类在数据库及搜索引擎中得到广泛的应用,K-近邻(KNN)算法是常用于中文文本分类中的分类方法,但K-近邻在分类过程中需要存储所有的训练样本,并且直到待测样本需要分类时才建立分类,而且还存在类倾斜现象以及存储和计算的开销大等缺陷。单类SVM对只有一类的分类问题具有很好的效果,但不适用于多类分类问题,因此针对KNN存在的缺陷及单类SVM的特点提出One Class SVM-KNN算法,并给出了算法的定义及详细分析。通过实验证明此方法很好地克服了KNN算法的缺陷,并且查全率、查准率明显优于K-近邻算法。

后现代语境中西文理论术语的“汉译”及其界定——以布尔迪厄《区隔》中的classe、jugement和habitus为例

产生于后现代语境中的西方思想在进入当下的汉语语境时往往容易出现种种的误读,其中一个关键的原因就是,生成于现代性语境中的汉语语汇与西方后现代思想取向之间存在着某种"质"的差异。布尔迪厄的无价值倾向的"阶级/阶层(classe)"被打上了明显意识形态的印迹,"趣味判断(jugement)"则被直接对应于康德的"判断力",而作为具有本体意味的"生存样态"出现的"habitus"也只是被定位在"习性/习得"的层面上。"新学语"的输入建构着全新的知识范型与思维结构,而既有的汉语语汇,特别是对关键性核心理论术语的表述却又潜在地误导我们对诸多原创性思想的理解。从这个意义上说,重新清理和界定汉语理论术语的基本内涵也许是"复活"中国思想所不可或缺的重要前提。

小学低学段语文优质课堂师生互动特征研究--基于CLASS 课堂评价打分系统的分析

采用美国弗吉尼亚大学研究团队开发的课堂评价打分系统(CLASS),围绕情感支持、课堂组织、教学支持三个领域及下设的十个维度,对20节小学低学段语文优质课堂的师生互动状况进行深度观察,探索优质课堂环境下师生互动的整体水平及各维度之间的相互关系,并综合量化数据和质性分析得出研究结论。研究发现,小学低学段语文优质课堂在情感支持方面,能较好地激发教师的职业热情,并培养学生自主自立的精神与能力;在课堂组织方面,能以课堂实效为目标,创设高品质的教学活动;在教学支持方面,能营造安全的思维环境,促进师生深度互动。

新商科的理论内涵、运行逻辑和实践路径

新商科是构建中国特色商科理论,回应时代之问,培育新时代商科人才的关键学科,是我国打造世界水平、中国特色文科人才培养体系的重大战略举措。文章阐释了新商科的理论内涵,揭示了新商科的运行逻辑,描绘了新商科的实践路径,并提出要直面新形势、新问题、新竞争、新要求和新目标,从打造中国特色新商科、构建商科教育新体系、拓展商科教育新视野、培育商科领域新人才、推动商科教育新发展五方面,加速中国特色、世界一流新商科的理论构建和新商科教育的高质量发展。

铸牢中华民族共同体意识视阈下剪纸课文化育人的价值思考

剪纸艺术作为重要的非物质文化遗产,是我国民间传统手工艺术形式之一,是中华优秀传统文化的重要组成部分,也是铸牢中华民族共同体意识的重要资源。将剪纸艺术引入教育教学不仅可以保护和传承非物质文化遗产,而且可以加强民间文化艺术教育、提升青少年学生人文素养,更有助于传承和弘扬中华优秀传统文化、讲好中华民族共同体故事,铸牢中华民族共同体意识。把铸牢中华民族共同体意识融入剪纸课文化育人全过程,不仅可以充实学校课程内容,而且可以充分展现剪纸艺术的魅力,拓展青少年学生感受中华优秀传统文化的途径,让其了解和体验中华文化的魅力,提高他们的审美能力和文化素养,促进各民族在理想、信念、情感、文化上的团结统一,让青少年学生在剪纸艺术的学习创作过程中铸牢中华民族共同体意识。

争创“双一流”中医药高校背景下构建良好导学关系模式探索

[目的]探索在争创“双一流”中医药高校的背景下,导学关系新模式的构建举措,以不断提升中医药高校研究生培养质量。[方法]在争创“双一流”中医药高校背景下,介绍构建良好导学关系的现实意义,基于导师和研究生两大主体的视角,对当前中医药高校研究生培养中导学关系存在的突出问题进行分析。[结果]以浙江中医药大学为例,从强化“尊师重道”正向影响、纠正导学关系失衡和完善相关制度三个方面入手,提出了相应的可行性建议。通过良好导学关系的构建,导学关系普遍得到了正向影响,师生间的沟通更加密切而高效。通过一系列正向激励机制,导师在学术引领、学业指导和生活关怀等方面更加积极主动地为研究生提供支持和帮助,研究生也更加积极地配合导师开展各项科研工作,研究生发表学术论文的数量和质量得到了显著的提升,导师团队的科研、教学工作开展更加高效,进展显著。[结论]通过一系列有效举措,浙江中医药大学着力探索导学关系新模式的构建,显著改善了导学关系,不仅对提升研究生专业思想水平、沟通交流能力、科研创新能力有积极的作用,同时也为导师顺利完成教学科研工作提供了保障,值得进一步完善并推广。

北京协和医学院临床医学改革试点班中医课程的教学评价

目的对首三届北京协和医学院临床医学专业“4+4”改革试点班的《中医学》课程进行教学评价。方法采用问卷星无记名问卷调查方式,统计及分析总结2019级、2020级和2021级学生填写的《中医学教学问卷调查表》。结果大部分学生对中医感兴趣、认为有必要学习《中医学》课程,认为《中医学》授课教师充分备课,教学内容与教材、教学大纲、授课PPT相匹配,教学内容与临床紧密结合,对教学手段和方法满意。结论教学评价有助于教师总结教学经验和提升《中医学》课程的教学质量。

坚持教育、科技、人才“三位一体”加快推进中药学世界一流学科建设

以南京中医药大学为例,重点阐述了学校中药学学科在坚持党的领导、人才引领、科技创新、立德树人、服务需求导向等方面的特色化举措与成效。学校以中国特色、世界一流为目标,以立德树人为根本任务,坚持目标和问题导向,以深化改革激发创新动力,坚持教育、科技、人才“三位一体”,以高质量发展推进中药学世界一流学科建设,为中药学的世界一流学科建设提供了借鉴和发展思路。

疾病诊断相关分组支付方式对三甲中医院财务管理的影响及应对策略

探讨了疾病诊断相关分组(DRG)支付方式对三甲中医院财务管理的影响并提出应对策略。结合所在医院随机抽取的某月各科室相关数据,运用DRG支付方式下的相应指标并结合波士顿矩阵理论模型进行全面综合评价分析。2023年1月,所在医院5个科室CMI值高于全院平均水平,且盈余情况良好;8个科室CMI值低于全院平均水平,但有盈余;14个科室CMI值低于全院平均水平,且还有亏损;8个科室CMI值高于全院平均水平,却有亏损。DRG支付方式对三甲中医院来说,既是机遇也是挑战,对三甲中医院信息化数据系统、成本核算精细化提出高要求,对预算管理、拓展收入增长内涵提出新要求。三甲中医院应重视病案质量主体培训,强化成本内控,转为质量效益型运营管理模式,应用临床路径以“提质控费”,发挥中医药优势学科,结合中医治疗特点来制定适合中医发展的DRG支付方式。

综合性医科大学中药学专业建设的实践与思考——以首都医科大学为例

首都医科大学中药学专业在长期办学实践中分析身处综合性医科大学的教育教学资源特点,结合生源及其就业趋向,逐步树立了院校教育与师承教育相结合培养中药专业人才的精品教育理念,实施一系列深化中药学专业教育教学综合改革的措施,使人才培养质量显著提升。通过专业认证更加明确自身存在的问题,并制定了持续推进国家级一流专业建设、进一步提升人才培养质量的具体措施。