A novel estrogen dendrimer has been synthesized through a combination of divergent and convergent approaches in 9 practical steps and in good yields. It was characterized and confirmed by elemental analysis, FT-IR, MS...A novel estrogen dendrimer has been synthesized through a combination of divergent and convergent approaches in 9 practical steps and in good yields. It was characterized and confirmed by elemental analysis, FT-IR, MS, 1H NMR, 13C NMR. The dendrimer contains 16 estrone units and is potentially a useful tool for the studies of estrogen actions.展开更多
基金supported by the National Key Basic Research Program of China(973 Program) Foundation (2010CB529905)
文摘A novel estrogen dendrimer has been synthesized through a combination of divergent and convergent approaches in 9 practical steps and in good yields. It was characterized and confirmed by elemental analysis, FT-IR, MS, 1H NMR, 13C NMR. The dendrimer contains 16 estrone units and is potentially a useful tool for the studies of estrogen actions.