Three water-soluble β-alanine C 60 adducts with different addition numbers, C 60(NHCH 2CH 2COONa) nH n(n=1,5,9), were synthesized. The products were characterized by FTIR, 1H NMR and elemental analysis. The antioxida...Three water-soluble β-alanine C 60 adducts with different addition numbers, C 60(NHCH 2CH 2COONa) nH n(n=1,5,9), were synthesized. The products were characterized by FTIR, 1H NMR and elemental analysis. The antioxidant activity of these C 60 adducts as the quencher for superoxide anion radical O -· 2 was evaluated by chemiluminescence in the system of pyrogallol-luminol. The results indicate that the three C 60 derivatives are all excellent quencher for superoxide anion radical O -· 2. The concentrations of 50% inhibition are 252, 140, 112 μmol/L respectively. This high efficiency should be attributed to many factors such as the numbers of remaining double bonds, donor effect of amino group and steric effect. However, the above results also suggest the effect of the adducted β-alanine groups is predominated in this system.展开更多
The activity on O-2 of ligands from ovanillin and amino acid and their complexes were studied in this paper.Results showed that ligands and their complexes may inhibit the formation of O-2.Zn(Ⅱ)complexes di...The activity on O-2 of ligands from ovanillin and amino acid and their complexes were studied in this paper.Results showed that ligands and their complexes may inhibit the formation of O-2.Zn(Ⅱ)complexes display remarkable activity of inhibiting the formation of O-2.展开更多
Two diphenylamine compoundsdiclofenac copper(II)and clofenamic copper(II)were synthesized.The molecular composition and structure of these analogues of SOD were determined by IR spectrum and elemental analysis. The ...Two diphenylamine compoundsdiclofenac copper(II)and clofenamic copper(II)were synthesized.The molecular composition and structure of these analogues of SOD were determined by IR spectrum and elemental analysis. The SOD like activity of both analogues of SOD and natural SOD were measured by the modification of NBTillumination method in water solution.The results show that these compounds have good SODlike activities.展开更多
文摘Three water-soluble β-alanine C 60 adducts with different addition numbers, C 60(NHCH 2CH 2COONa) nH n(n=1,5,9), were synthesized. The products were characterized by FTIR, 1H NMR and elemental analysis. The antioxidant activity of these C 60 adducts as the quencher for superoxide anion radical O -· 2 was evaluated by chemiluminescence in the system of pyrogallol-luminol. The results indicate that the three C 60 derivatives are all excellent quencher for superoxide anion radical O -· 2. The concentrations of 50% inhibition are 252, 140, 112 μmol/L respectively. This high efficiency should be attributed to many factors such as the numbers of remaining double bonds, donor effect of amino group and steric effect. However, the above results also suggest the effect of the adducted β-alanine groups is predominated in this system.
文摘The activity on O-2 of ligands from ovanillin and amino acid and their complexes were studied in this paper.Results showed that ligands and their complexes may inhibit the formation of O-2.Zn(Ⅱ)complexes display remarkable activity of inhibiting the formation of O-2.
文摘Two diphenylamine compoundsdiclofenac copper(II)and clofenamic copper(II)were synthesized.The molecular composition and structure of these analogues of SOD were determined by IR spectrum and elemental analysis. The SOD like activity of both analogues of SOD and natural SOD were measured by the modification of NBTillumination method in water solution.The results show that these compounds have good SODlike activities.
