The recent SARS-CoV-2 pandemic renewed interest in other previously discovered human coronaviruses—the non-severe acute respiratory syndrome human coronavirus (non-SARS hCoVs) and this study is a starting point for a...The recent SARS-CoV-2 pandemic renewed interest in other previously discovered human coronaviruses—the non-severe acute respiratory syndrome human coronavirus (non-SARS hCoVs) and this study is a starting point for a closer investigation of those. With the pandemic behind us we believe it to be important to also examine the current and past respiratory pathogen landscape in the patient population in our care. Therefore, 954 nasopharyngeal swabs of patients with respiratory diseases collected between October 2018 and March 2020 were tested against the pathogens Mycoplasma pneumoniae, Bordetella pertussis, Influenza A and virus, Human metapneumovirus, respiratory syncytial virus, Parainfluenza virus, human Adenovirus and Polyoma virus BK/JC. Swabs negative against these pathogens were further tested for OC43 and 229E by RT-qPCR. Human coronaviruses 229E and OC43 were proven as the causative agents in a considerable number of cases, confirmed by PCR. Overall, our results show that those two non-SARS hCoVs were responsible for 13.9% (11 of 79) of infections with flu-like symptoms of unknown etiology in the study area. In the subsequent seroprevalence study, it was shown that the seroprevalence rate of IgG antibodies against 229E and OC43 was over 50%, indicating that a big part of the population in our study area has been in contact with these non-SARS-CoVs and has built the specific humoral immune response accordingly.展开更多
跟随AMD推出RX 7600显卡的节奏,各大AIB厂商也在此时推出了自家的各款非公版产品。作为核心AIB厂商之一的蓝宝石,也在第一时间推出了相应的产品—RX 76008G D6白金版OC。有别于亮银酷炫的R X 7900 X T X、R X 7900XT超白金系列,此次登场...跟随AMD推出RX 7600显卡的节奏,各大AIB厂商也在此时推出了自家的各款非公版产品。作为核心AIB厂商之一的蓝宝石,也在第一时间推出了相应的产品—RX 76008G D6白金版OC。有别于亮银酷炫的R X 7900 X T X、R X 7900XT超白金系列,此次登场的RX 76008G D6白金版OC(后文简称RX 7600白金版OC)在设计风格上沿袭了白金版系列家族的标志性风格—黑红血脉。展开更多
文摘The recent SARS-CoV-2 pandemic renewed interest in other previously discovered human coronaviruses—the non-severe acute respiratory syndrome human coronavirus (non-SARS hCoVs) and this study is a starting point for a closer investigation of those. With the pandemic behind us we believe it to be important to also examine the current and past respiratory pathogen landscape in the patient population in our care. Therefore, 954 nasopharyngeal swabs of patients with respiratory diseases collected between October 2018 and March 2020 were tested against the pathogens Mycoplasma pneumoniae, Bordetella pertussis, Influenza A and virus, Human metapneumovirus, respiratory syncytial virus, Parainfluenza virus, human Adenovirus and Polyoma virus BK/JC. Swabs negative against these pathogens were further tested for OC43 and 229E by RT-qPCR. Human coronaviruses 229E and OC43 were proven as the causative agents in a considerable number of cases, confirmed by PCR. Overall, our results show that those two non-SARS hCoVs were responsible for 13.9% (11 of 79) of infections with flu-like symptoms of unknown etiology in the study area. In the subsequent seroprevalence study, it was shown that the seroprevalence rate of IgG antibodies against 229E and OC43 was over 50%, indicating that a big part of the population in our study area has been in contact with these non-SARS-CoVs and has built the specific humoral immune response accordingly.
文摘跟随AMD推出RX 7600显卡的节奏,各大AIB厂商也在此时推出了自家的各款非公版产品。作为核心AIB厂商之一的蓝宝石,也在第一时间推出了相应的产品—RX 76008G D6白金版OC。有别于亮银酷炫的R X 7900 X T X、R X 7900XT超白金系列,此次登场的RX 76008G D6白金版OC(后文简称RX 7600白金版OC)在设计风格上沿袭了白金版系列家族的标志性风格—黑红血脉。
