To improve the performance of an automated material handling system (AMHS) in 300 mm semiconductor fabrication plants (FABs), an overhead-hoist-transport (OHT) vehicle dispatching problem was described for semiconduct...To improve the performance of an automated material handling system (AMHS) in 300 mm semiconductor fabrication plants (FABs), an overhead-hoist-transport (OHT) vehicle dispatching problem was described for semiconductor FABs. An original wafer lot dispatching policy was proposed. To minimize costs due to transportation logic, a dispatching rule based on an adapted Hungarian algorithm was presented, and six factors were considered. In addition to the recurring parameters, two original parameters of the vehicles utilization and wafer lot priority were considered to evaluate system performance. To obtain a balanced efficiency regarding the FAB output factors, simulation and sensitive analysis were used to find the best weight parameters of the cost matrix. In particular, a high rate of priority wafer lots (greater than 20%) and vehicles utilization (greater than 75%) are obtained without penalizing the efficiency of the FABs. The results indicate that the proposed dispatching policy is valid and practical.展开更多
Overhead-hoist-transporters (OHTs) have become the most appropriate tools to transport wafer lots between inter-bay and intra-bay in united layouts of automated material handling systems (AMHSs) in 300 mm semiconducto...Overhead-hoist-transporters (OHTs) have become the most appropriate tools to transport wafer lots between inter-bay and intra-bay in united layouts of automated material handling systems (AMHSs) in 300 mm semiconductor wafer fabrications. To obtain a conflict-free scheduling solution, an intelligent multi-agent-based control system framework was built to support the AMHSs. And corresponding algorithms and rules were proposed to implement cooperation among agents. On the basis of the mentioned above, a time-constraint-based heuristic scheduling algorithm was presented to support the routing decision agent in searching the conflict-free shortest path. In the construction of the algorithm, the conflicted intervals of the k-shortest-route were identified with the time window theory. The most available path was chosen with an objective of the minimum completion time. The back tracking method was combined to finish the routing scheduling. Finally, experiments of the proposed method were simulated. The results show that the multi-agent framework is suitable and the proposed scheduling algorithm is feasible and valid.展开更多
OHTS is the first large-scale study to demonstrate that lowering eye pressure can safely and effectively delay and possibly prevent development of glaucoma. While the academic community and textbooks generally take th...OHTS is the first large-scale study to demonstrate that lowering eye pressure can safely and effectively delay and possibly prevent development of glaucoma. While the academic community and textbooks generally take the side of withholding treatment, perhaps most general ophthalmologists around the world treat anyone with a pressure greater than the low 20s or with risk fac-展开更多
基于正交Haar变换(orthogonal Haar transform,OHT)的模板匹配算法在处理二维图像时采用条形和来替代积分图,从而获得了较高的运行效率,但它要求模板必须是标准大小的,即模板的高和宽必须相等且为2的幂次.为解决OHT算法的这一问题,提出...基于正交Haar变换(orthogonal Haar transform,OHT)的模板匹配算法在处理二维图像时采用条形和来替代积分图,从而获得了较高的运行效率,但它要求模板必须是标准大小的,即模板的高和宽必须相等且为2的幂次.为解决OHT算法的这一问题,提出了另一种基于拟Haar变换(quasi Haar transform,QHT)的模板匹配算法,它使用树分解策略来加速非标准模板时的匹配处理.QHT算法不仅能处理非标准模板的情况,也同样能处理标准模板的情况.在标准模板情况下,实验结果表明,QHT算法在低噪声等级时比OHT算法拥有更快的运行速度.展开更多
Liver cancer is one of the most threatening diseases in Chinese population. Just like in other tissues, tumor initiation and development in liver involve multiple steps of genetic and epigenetic alterations with sever...Liver cancer is one of the most threatening diseases in Chinese population. Just like in other tissues, tumor initiation and development in liver involve multiple steps of genetic and epigenetic alterations with several unknown details. However, unlike in other tissues, a tissue specific inducible Cre recombinase system that allows temporal and spatial deletion of a target DNA fragment is still not available for in vivo functional gene annotation in hepatocytes. In our pursuit to establish such a mouse model, we designed a dual inducible Cre transgene system and tested it in cultured cells. By combining a CCAAT/enhancer binding protein β （C/EBP β） promoter derived Tet-off expression system and the estrogen receptor （ER） mediated functional control, we show a desirable profile of both hepatocyte-specificity and regulability of the Cre expression in a series of critical assessments in the cell culture system, which provides confidence in continuation of our ongoing pursuit in mouse.展开更多
Introduction: Posner-Schlossman syndrome is an infrequent in-flamatory glaucoma Some aspects of this disease remain controversial. Purpose: To present our experience in this specific type of glaucoma Methods: We have ...Introduction: Posner-Schlossman syndrome is an infrequent in-flamatory glaucoma Some aspects of this disease remain controversial. Purpose: To present our experience in this specific type of glaucoma Methods: We have reviewed the files of glaucoma diagnosis for the last five years. Ten patients fulfil the展开更多
Purpose: The main objective was to analyze the relationship between maximum cup depth (MCD), mean defect (MD), central corneal thickness (CCT), age and disc area, in patients with ocular hypertension (OHT) and primary...Purpose: The main objective was to analyze the relationship between maximum cup depth (MCD), mean defect (MD), central corneal thickness (CCT), age and disc area, in patients with ocular hypertension (OHT) and primary open angle glaucoma (POAG). Methods: Cross-sectional study of patients diagnosed with OHT and POAG. Visual fields were obtained using an Octopus 300 analyzer, TOP strategy. MCD and disc area were obtained using a Heidelberg Retina Tomograph. Results: The study sample comprised 234 eyes of 143 patients, 91 women and 52 men, mean age 63.55 years (SD 10.49). Mean values were: MCD 0.52 mm (SD 0.27), MD 2.78 dB (SD 5.02), CCT 543.5 μm (SD 36.63), IOP 16.73 mmHg (SD 2.93), and disc area 2.01 mm<sup>2</sup> (SD 0.39). A significant correlation was observed between MCD and age in patients under 60 years, between MCD and disc area, and between MD and disc area. Conclusions: Our study showed a correlation between MCD and age which was significant in patients under 60 years of age, between MCD and disc area and between MD and disc area, suggesting that the larger the disc area, the greater the MCD and the MD in patients with OHT and POAG.展开更多
基金National Natural Science Foundations of China ( No. 71071115,No. 61273035)National High-Tech R&D Program for CIMS,China ( No. 2009AA043000)
文摘To improve the performance of an automated material handling system (AMHS) in 300 mm semiconductor fabrication plants (FABs), an overhead-hoist-transport (OHT) vehicle dispatching problem was described for semiconductor FABs. An original wafer lot dispatching policy was proposed. To minimize costs due to transportation logic, a dispatching rule based on an adapted Hungarian algorithm was presented, and six factors were considered. In addition to the recurring parameters, two original parameters of the vehicles utilization and wafer lot priority were considered to evaluate system performance. To obtain a balanced efficiency regarding the FAB output factors, simulation and sensitive analysis were used to find the best weight parameters of the cost matrix. In particular, a high rate of priority wafer lots (greater than 20%) and vehicles utilization (greater than 75%) are obtained without penalizing the efficiency of the FABs. The results indicate that the proposed dispatching policy is valid and practical.
基金National Natural Science Foundations of China(No. 61273035,No. 71071115)National High-Tech R&D Program for CIMS,China(No. 2009AA043000)
文摘Overhead-hoist-transporters (OHTs) have become the most appropriate tools to transport wafer lots between inter-bay and intra-bay in united layouts of automated material handling systems (AMHSs) in 300 mm semiconductor wafer fabrications. To obtain a conflict-free scheduling solution, an intelligent multi-agent-based control system framework was built to support the AMHSs. And corresponding algorithms and rules were proposed to implement cooperation among agents. On the basis of the mentioned above, a time-constraint-based heuristic scheduling algorithm was presented to support the routing decision agent in searching the conflict-free shortest path. In the construction of the algorithm, the conflicted intervals of the k-shortest-route were identified with the time window theory. The most available path was chosen with an objective of the minimum completion time. The back tracking method was combined to finish the routing scheduling. Finally, experiments of the proposed method were simulated. The results show that the multi-agent framework is suitable and the proposed scheduling algorithm is feasible and valid.
文摘OHTS is the first large-scale study to demonstrate that lowering eye pressure can safely and effectively delay and possibly prevent development of glaucoma. While the academic community and textbooks generally take the side of withholding treatment, perhaps most general ophthalmologists around the world treat anyone with a pressure greater than the low 20s or with risk fac-
文摘基于正交Haar变换(orthogonal Haar transform,OHT)的模板匹配算法在处理二维图像时采用条形和来替代积分图,从而获得了较高的运行效率,但它要求模板必须是标准大小的,即模板的高和宽必须相等且为2的幂次.为解决OHT算法的这一问题,提出了另一种基于拟Haar变换(quasi Haar transform,QHT)的模板匹配算法,它使用树分解策略来加速非标准模板时的匹配处理.QHT算法不仅能处理非标准模板的情况,也同样能处理标准模板的情况.在标准模板情况下,实验结果表明,QHT算法在低噪声等级时比OHT算法拥有更快的运行速度.
基金supported by Shanghai Science Foundation grants,National Science Foundation of China(No.30570850 and 10574134)National Research Program for Basic Research of China(No.2004CB518804)+1 种基金National Research Program for High Technology(No.2006AA02Z-320 and 2006AA 02Z197)European 6th Program(LSHBCT-2005-019067).
文摘Liver cancer is one of the most threatening diseases in Chinese population. Just like in other tissues, tumor initiation and development in liver involve multiple steps of genetic and epigenetic alterations with several unknown details. However, unlike in other tissues, a tissue specific inducible Cre recombinase system that allows temporal and spatial deletion of a target DNA fragment is still not available for in vivo functional gene annotation in hepatocytes. In our pursuit to establish such a mouse model, we designed a dual inducible Cre transgene system and tested it in cultured cells. By combining a CCAAT/enhancer binding protein β （C/EBP β） promoter derived Tet-off expression system and the estrogen receptor （ER） mediated functional control, we show a desirable profile of both hepatocyte-specificity and regulability of the Cre expression in a series of critical assessments in the cell culture system, which provides confidence in continuation of our ongoing pursuit in mouse.
文摘Introduction: Posner-Schlossman syndrome is an infrequent in-flamatory glaucoma Some aspects of this disease remain controversial. Purpose: To present our experience in this specific type of glaucoma Methods: We have reviewed the files of glaucoma diagnosis for the last five years. Ten patients fulfil the
文摘Purpose: The main objective was to analyze the relationship between maximum cup depth (MCD), mean defect (MD), central corneal thickness (CCT), age and disc area, in patients with ocular hypertension (OHT) and primary open angle glaucoma (POAG). Methods: Cross-sectional study of patients diagnosed with OHT and POAG. Visual fields were obtained using an Octopus 300 analyzer, TOP strategy. MCD and disc area were obtained using a Heidelberg Retina Tomograph. Results: The study sample comprised 234 eyes of 143 patients, 91 women and 52 men, mean age 63.55 years (SD 10.49). Mean values were: MCD 0.52 mm (SD 0.27), MD 2.78 dB (SD 5.02), CCT 543.5 μm (SD 36.63), IOP 16.73 mmHg (SD 2.93), and disc area 2.01 mm<sup>2</sup> (SD 0.39). A significant correlation was observed between MCD and age in patients under 60 years, between MCD and disc area, and between MD and disc area. Conclusions: Our study showed a correlation between MCD and age which was significant in patients under 60 years of age, between MCD and disc area and between MD and disc area, suggesting that the larger the disc area, the greater the MCD and the MD in patients with OHT and POAG.
