A Rice Growth Models (RGM) System by Object-Oriented Programming with Visual C++

Object-oriented programming divides the crop production into subsystems and simulates their behaviors. Many classes were designed to simulate the behaviors of different parts or different physiological processes in crop production system. At the same time, many classes have to be employed for bettering user's interface. But how to manage these classes on a higher level to cooperate them into a perfect system is another problem to study. The Rice Growth Models (RGM) system represents an effort to define and implement a framework to manage these classes. In RGM system, the classes were organized into the model-document-view architecture to separate the domain models, data management and user interface. A single document with multiple views interface frame window was adopted in RGM. In the architectures, the simulation models only exchange data with documents while documents act as intermediacies between simulation models and interfaces. Views get data from documents and show the results to users. The classes for the different functions can be grouped into different architectures. Different architectures communicate with each other through documents. The classes for the different functions can be grouped into different architectures. By using the architecture, communication between classes is more efficient. Modeler can add classes in architectures or other architectures to extend the system without having to change system structure, which is useful for construction and maintenance of agricultural system models.

Concurrent Object-Oriented Programming Based on MPI

Object-oriented model possesses inherent concurrency. Integration of concurrency and object-orientation is a promising new field. MPI is a message-passing standard and has been adopted by more and more systems. This paper proposes a novel approach to realize concurrent object-oriented programming based on Message-passing interface(MPI) in which future method communication is adopted between concurrent objects. A state behavior set is proposed to solve inheritance anomaly, and a bounded buffer is taken as an example to illustrate this proposal. The definition of ParaMPI class, which is the most important class in the concurrent class library, and implementation issues are briefly described.

An Approach to Detect Structural Development Defects in Object-Oriented Programs

Structural development defects essentially refer to code structure that violates object-oriented design principles. They make program maintenance challenging and deteriorate software quality over time. Various detection approaches, ranging from traditional heuristic algorithms to machine learning methods, are used to identify these defects. Ensemble learning methods have strengthened the detection of these defects. However, existing approaches do not simultaneously exploit the capabilities of extracting relevant features from pre-trained models and the performance of neural networks for the classification task. Therefore, our goal has been to design a model that combines a pre-trained model to extract relevant features from code excerpts through transfer learning and a bagging method with a base estimator, a dense neural network, for defect classification. To achieve this, we composed multiple samples of the same size with replacements from the imbalanced dataset MLCQ1. For all the samples, we used the CodeT5-small variant to extract features and trained a bagging method with the neural network Roberta Classification Head to classify defects based on these features. We then compared this model to RandomForest, one of the ensemble methods that yields good results. Our experiments showed that the number of base estimators to use for bagging depends on the defect to be detected. Next, we observed that it was not necessary to use a data balancing technique with our model when the imbalance rate was 23%. Finally, for blob detection, RandomForest had a median MCC value of 0.36 compared to 0.12 for our method. However, our method was predominant in Long Method detection with a median MCC value of 0.53 compared to 0.42 for RandomForest. These results suggest that the performance of ensemble methods in detecting structural development defects is dependent on specific defects.

OBJECT-ORIENTED FINITE ELEMENT ANALYSIS AND PROGRAMMING IN VC++

The design of finite element analysis program using object-oriented programming (OOP) techniques is presented. The objects, classes and the subclasses used in the programming are explained. The system of classes library of finite element analysis program and Windows-type Graphical User Interfaces by VC + + and its MFC are developed. The reliability, reusability and extensibility of program are enhanced. It is a reference to develop the large-scale, versatile and powerful systems of object-oriented finite element software.

Recent Progress in Reinforcement Learning and Adaptive Dynamic Programming for Advanced Control Applications

Reinforcement learning(RL) has roots in dynamic programming and it is called adaptive/approximate dynamic programming(ADP) within the control community. This paper reviews recent developments in ADP along with RL and its applications to various advanced control fields. First, the background of the development of ADP is described, emphasizing the significance of regulation and tracking control problems. Some effective offline and online algorithms for ADP/adaptive critic control are displayed, where the main results towards discrete-time systems and continuous-time systems are surveyed, respectively.Then, the research progress on adaptive critic control based on the event-triggered framework and under uncertain environment is discussed, respectively, where event-based design, robust stabilization, and game design are reviewed. Moreover, the extensions of ADP for addressing control problems under complex environment attract enormous attention. The ADP architecture is revisited under the perspective of data-driven and RL frameworks,showing how they promote ADP formulation significantly.Finally, several typical control applications with respect to RL and ADP are summarized, particularly in the fields of wastewater treatment processes and power systems, followed by some general prospects for future research. Overall, the comprehensive survey on ADP and RL for advanced control applications has d emonstrated its remarkable potential within the artificial intelligence era. In addition, it also plays a vital role in promoting environmental protection and industrial intelligence.

In vivo astrocyte reprogramming following spinal cord injury

Harmful and helpful roles of astrocytes in spinal cord injury(SCI):SCI induce gradable sensory,motor and autonomic impairments that correlate with the lesion severity and the rostro-caudal location of the injury site.The absence of spontaneous axonal regeneration after injury results from neuron-intrinsic and neuron-extrinsic parameters.Indeed,not only adult neurons display limited capability to regrow axons but also the injury environment contains inhibitors to axonal regeneration and a lack of growth-promoting factors.Amongst other cell populations that respond to the lesion,reactive astrocytes were first considered as only detrimental to spontaneous axonal regeneration.Indeed,astrocytes.

Transcriptional reprogramming during human osteoclast differentiation identifies regulators of osteoclast activity

Enhanced osteoclastogenesis and osteoclast activity contribute to the development of osteoporosis,which is characterized by increased bone resorption and inadequate bone formation.As novel antiosteoporotic therapeutics are needed,understanding the genetic regulation of human osteoclastogenesis could help identify potential treatment targets.This study aimed to provide an overview of transcriptional reprogramming during human osteoclast differentiation.Osteoclasts were differentiated from CD14+monocytes from eight female donors.RNA sequencing during differentiation revealed 8980 differentially expressed genes grouped into eight temporal patterns conserved across donors.These patterns revealed distinct molecular functions associated with postmenopausal osteoporosis susceptibility genes based on RNA from iliac crest biopsies and bone mineral density SNPs.Network analyses revealed mutual dependencies between temporal expression patterns and provided insight into subtype-specific transcriptional networks.The donor-specific expression patterns revealed genes at the monocyte stage,such as filamin B(FLNB)and oxidized low-density lipoprotein receptor 1(OLR1,encoding LOX-1),that are predictive of the resorptive activity of mature osteoclasts.The expression of differentially expressed G-protein coupled receptors was strong during osteoclast differentiation,and these receptors are associated with bone mineral density SNPs,suggesting that they play a pivotal role in osteoclast differentiation and activity.The regulatory effects of three differentially expressed G-protein coupled receptors were exemplified by in vitro pharmacological modulation of complement 5 A receptor 1(C5AR1),somatostatin receptor 2(SSTR2),and free fatty acid receptor 4(FFAR4/GPR120).Activating C5AR1 enhanced osteoclast formation,while activating SSTR2 decreased the resorptive activity of mature osteoclasts,and activating FFAR4 decreased both the number and resorptive activity of mature osteoclasts.In conclusion,we report the occurrence of transcriptional reprogramming during human osteoclast differentiation and identified SSTR2 and FFAR4 as antiresorptive G-protein coupled receptors and FLNB and LOX-1 as potential molecular markers of osteoclast activity.These data can help future investigations identify molecular regulators of osteoclast differentiation and activity and provide the basis for novel antiosteoporotic targets.

Improved Unit Commitment with Accurate Dynamic Scenarios Clustering Based on Multi-Parametric Programming and Benders Decomposition

Stochastic unit commitment is one of the most powerful methods to address uncertainty. However, the existingscenario clustering technique for stochastic unit commitment cannot accurately select representative scenarios,which threatens the robustness of stochastic unit commitment and hinders its application. This paper providesa stochastic unit commitment with dynamic scenario clustering based on multi-parametric programming andBenders decomposition. The stochastic unit commitment is solved via the Benders decomposition, which decouplesthe primal problem into the master problem and two types of subproblems. In the master problem, the committedgenerator is determined, while the feasibility and optimality of generator output are checked in these twosubproblems. Scenarios are dynamically clustered during the subproblem solution process through the multiparametric programming with respect to the solution of the master problem. In other words, multiple scenariosare clustered into several representative scenarios after the subproblem is solved, and the Benders cut obtainedby the representative scenario is generated for the master problem. Different from the conventional stochasticunit commitment, the proposed approach integrates scenario clustering into the Benders decomposition solutionprocess. Such a clustering approach could accurately cluster representative scenarios that have impacts on theunit commitment. The proposed method is tested on a 6-bus system and the modified IEEE 118-bus system.Numerical results illustrate the effectiveness of the proposed method in clustering scenarios. Compared withthe conventional clustering method, the proposed method can accurately select representative scenarios whilemitigating computational burden, thus guaranteeing the robustness of unit commitment.

Uncertainty quantification of inverse analysis for geomaterials using probabilistic programming

Uncertainty is an essentially challenging for safe construction and long-term stability of geotechnical engineering.The inverse analysis is commonly utilized to determine the physico-mechanical parameters.However,conventional inverse analysis cannot deal with uncertainty in geotechnical and geological systems.In this study,a framework was developed to evaluate and quantify uncertainty in inverse analysis based on the reduced-order model(ROM)and probabilistic programming.The ROM was utilized to capture the mechanical and deformation properties of surrounding rock mass in geomechanical problems.Probabilistic programming was employed to evaluate uncertainty during construction in geotechnical engineering.A circular tunnel was then used to illustrate the proposed framework using analytical and numerical solution.The results show that the geomechanical parameters and associated uncertainty can be properly obtained and the proposed framework can capture the mechanical behaviors under uncertainty.Then,a slope case was employed to demonstrate the performance of the developed framework.The results prove that the proposed framework provides a scientific,feasible,and effective tool to characterize the properties and physical mechanism of geomaterials under uncertainty in geotechnical engineering problems.

Rapid Prototype Development Approach for Genetic Programming

Genetic Programming (GP) is an important approach to deal with complex problem analysis and modeling, and has been applied in a wide range of areas. The development of GP involves various aspects, including design of genetic operators, evolutionary controls and implementations of heuristic strategy, evaluations and other mechanisms. When designing genetic operators, it is necessary to consider the possible limitations of encoding methods of individuals. And when selecting evolutionary control strategies, it is also necessary to balance search efficiency and diversity based on representation characteristics as well as the problem itself. More importantly, all of these matters, among others, have to be implemented through tedious coding work. Therefore, GP development is both complex and time-consuming. To overcome some of these difficulties that hinder the enhancement of GP development efficiency, we explore the feasibility of mutual assistance among GP variants, and then propose a rapid GP prototyping development method based on πGrammatical Evolution (πGE). It is demonstrated through regression analysis experiments that not only is this method beneficial for the GP developers to get rid of some tedious implementations, but also enables them to concentrate on the essence of the referred problem, such as individual representation, decoding means and evaluation. Additionally, it provides new insights into the roles of individual delineations in phenotypes and semantic research of individuals.

Adaptive Optimal Discrete-Time Output-Feedback Using an Internal Model Principle and Adaptive Dynamic Programming

In order to address the output feedback issue for linear discrete-time systems, this work suggests a brand-new adaptive dynamic programming(ADP) technique based on the internal model principle(IMP). The proposed method, termed as IMP-ADP, does not require complete state feedback-merely the measurement of input and output data. More specifically, based on the IMP, the output control problem can first be converted into a stabilization problem. We then design an observer to reproduce the full state of the system by measuring the inputs and outputs. Moreover, this technique includes both a policy iteration algorithm and a value iteration algorithm to determine the optimal feedback gain without using a dynamic system model. It is important that with this concept one does not need to solve the regulator equation. Finally, this control method was tested on an inverter system of grid-connected LCLs to demonstrate that the proposed method provides the desired performance in terms of both tracking and disturbance rejection.

A Dimensional Reduction Approach Based on Essential Constraints in Linear Programming

This paper presents a new dimension reduction strategy for medium and large-scale linear programming problems. The proposed method uses a subset of the original constraints and combines two algorithms: the weighted average and the cosine simplex algorithm. The first approach identifies binding constraints by using the weighted average of each constraint, whereas the second algorithm is based on the cosine similarity between the vector of the objective function and the constraints. These two approaches are complementary, and when used together, they locate the essential subset of initial constraints required for solving medium and large-scale linear programming problems. After reducing the dimension of the linear programming problem using the subset of the essential constraints, the solution method can be chosen from any suitable method for linear programming. The proposed approach was applied to a set of well-known benchmarks as well as more than 2000 random medium and large-scale linear programming problems. The results are promising, indicating that the new approach contributes to the reduction of both the size of the problems and the total number of iterations required. A tree-based classification model also confirmed the need for combining the two approaches. A detailed numerical example, the general numerical results, and the statistical analysis for the decision tree procedure are presented.

An Object-Oriented Robot Programming and Simulation System

ＡｎＯｂｊｅｃｔ－ＯｒｉｅｎｔｅｄＲｏｂｏｔＰｒｏｇｒａｍｍｉｎｇａｎｄＳｉｍｕｌａｔｉｏｎＳｙｓｔｅｍＺＨＡＯＣｈｕｎｘｉａ；ＦＵＹｉｌｉ；ＷＡＮＧＳｈｕｇｕｏ；ＷＵＪｉｎｇ；ＣＡＩＨｅｇａｏ赵春霞，付宜立，王树国，吴菁，蔡鹤皋（ＲｏｂｏｔＲｅｓｅ...

Programming Logic Modeling and Cross-Program Defect Detection Method for Object-Oriented Code

Code defects can lead to software vulnerability and even produce vulnerability risks.Existing research shows that the code detection technology with text analysis can judge whether object-oriented code files are defective to some extent.However,these detection techniques are mainly based on text features and have weak detection capabilities across programs.Compared with the uncertainty of the code and text caused by the developer’s personalization,the programming language has a stricter logical specification,which reflects the rules and requirements of the language itself and the developer’s potential way of thinking.This article replaces text analysis with programming logic modeling,breaks through the limitation of code text analysis solely relying on the probability of sentence/word occurrence in the code,and proposes an object-oriented language programming logic construction method based on method constraint relationships,selecting features through hypothesis testing ideas,and construct support vector machine classifier to detect class files with defects and reduce the impact of personalized programming on detection methods.In the experiment,some representative Android applications were selected to test and compare the proposed methods.In terms of the accuracy of code defect detection,through cross validation,the proposed method and the existing leading methods all reach an average of more than 90%.In the aspect of cross program detection,the method proposed in this paper is superior to the other two leading methods in accuracy,recall and F1 value.

THE OBJECT-ORIENTED INTELLIGENT PROGRAMMING IN CAD/CAM

Design and manufacture organizations currently suffer from a number of problems that aignificantly affect their productivity.Despite their fragmented efforts to automate portioas of operations,they still suffer from 'islands' of designing and manufacturing automation,long lead time for semi-custom proposals and engineering work, lengthy cycles of product development and introduction into the market,and low morale due to boring,repetitive engineering and industrial design activities.Thereby,the integration of design and manufacturing poses to the CAD/CAM researchere a series of challenges.The paper introduces a methodology that allows for the integration of product design with manufacturing process planning and the application of a new software technology known as 'Object-Oriented Intelligent Programming' .The task is achieved through an object-oriented intelligent CAD/CAM environment where a design model from the CAD system can be analysed, and manufacturing process plans with specifications of machining can be automatically determined.The manufacturing information of a part is extracted from the 3D geometric model and the 2D engineering drawing,thus,both geometric and non-geometric attributes of a part can be obtained.

Sequential quadratic programming-based non-cooperative target distributed hybrid processing optimization method

The distributed hybrid processing optimization problem of non-cooperative targets is an important research direction for future networked air-defense and anti-missile firepower systems. In this paper, the air-defense anti-missile targets defense problem is abstracted as a nonconvex constrained combinatorial optimization problem with the optimization objective of maximizing the degree of contribution of the processing scheme to non-cooperative targets, and the constraints mainly consider geographical conditions and anti-missile equipment resources. The grid discretization concept is used to partition the defense area into network nodes, and the overall defense strategy scheme is described as a nonlinear programming problem to solve the minimum defense cost within the maximum defense capability of the defense system network. In the solution of the minimum defense cost problem, the processing scheme, equipment coverage capability, constraints and node cost requirements are characterized, then a nonlinear mathematical model of the non-cooperative target distributed hybrid processing optimization problem is established, and a local optimal solution based on the sequential quadratic programming algorithm is constructed, and the optimal firepower processing scheme is given by using the sequential quadratic programming method containing non-convex quadratic equations and inequality constraints. Finally, the effectiveness of the proposed method is verified by simulation examples.

Exploration on 5E Teaching Principle-based Education for the Object-oriented Software Construction Course

Most current object-oriented programming courses offered by domestic colleges and universities generally focus on the object-oriented programming language itself,i.e.,the programming grammar of the language,but ignore the design pattern.However,design patterns are essential to software engineering because they can solve common problems in software design and improve code reuse,readability,extensibility,and reliability.Our Object-oriented Software Construction Course is creative since it aims at cultivating students’object-oriented thinking as well as basic abilities required to construct high-quality,object-oriented software.Specifically,we exploit the 5E teaching principle during the education of this course,and present the whole pipeline in the paper.We also provide one case of the factory pattern to further demonstrate the implementation of the 5E teaching principle in the course.The effect of the 5E teaching principle has also been demonstrated.

Detecting Design Patterns in Object-Oriented Program Source Code by Using Metrics and Machine Learning

Detecting well-known design patterns in object-oriented program source code can help maintainers understand the design of a program. Through the detection, the understandability, maintainability, and reusability of object-oriented programs can be improved. There are automated detection techniques;however, many existing techniques are based on static analysis and use strict conditions composed on class structure data. Hence, it is difficult for them to detect and distinguish design patterns in which the class structures are similar. Moreover, it is difficult for them to deal with diversity in design pattern applications. To solve these problems in existing techniques, we propose a design pattern detection technique using source code metrics and machine learning. Our technique judges candidates for the roles that compose design patterns by using machine learning and measurements of several metrics, and it detects design patterns by analyzing the relations between candidates. It suppresses false negatives and distinguishes patterns in which the class structures are similar. As a result of experimental evaluations with a set of programs, we confirmed that our technique is more accurate than two conventional techniques.

Generating oligodendroglia from adult mesenchymal cells for transplantation:cell reprogramming or direct lineage conversion?

Cell replacement therapy has long been proposed as a treatment for the damaged nervous system.One of the most challenging aspects of such a strategy,however,is finding sources of donor cells for transplantation.Autologous neural cells are rarely an option as every cell in the nervous system has a defined function that would be lost if that cell was to be removed.One possibility would be sourcing precursor or differentiated cells from fetal tissues;however,aside from ethical issues,heterologous cells are at risk of immunological rejection in the long term.Methodological improvements over the past 15 years have led to the possibility that autologous non-neural cells could be used for cell transplantation through their conversion into neural derivatives.

Developmental exposure to thyroid disruptors:misprogramming of the brain's stem cells in later life?

Introduction:Ever since the discovery of neural stem cells(NSCs)in the adult mammalian brain,scientists have been trying to decipher which signals govern their turnover and lineage commitment to generate neurons and glia.Understanding their role in nervous tissue homeostasis can provide new insights into the etiology of several neurological disorders,and might one day be turned to our advantage to promote endogenous brain injury repair.Others and we have identified thyroid hormone(TH)as a key factor transcriptionally regulating NSC behavior in the largest niche of the adult mammalian brain:the subventricular zone(SVZ).