Large-field objective lens for multi-wavelength microscopy at mesoscale and submicron resolution

Conventional microscopes designed for submicron resolution in biological research are hindered by a limited field of view,typically around 1 mm.This restriction poses a challenge when attempting to simultaneously analyze various parts of a sample,such as different brain areas.In addition,conventional objective lenses struggle to perform consistently across the required range of wavelengths for brain imaging in vivo.Here we present a novel mesoscopic objective lens with an impressive field of view of 8 mm,a numerical aperture of 0.5,and a working wavelength range from 400 to 1000 nm.We achieved a resolution of 0.74μm in fluorescent beads imaging.The versatility of this lens was further demonstrated through high-quality images of mouse brain and kidney sections in a wide-field imaging system,a confocal laser scanning system,and a two-photon imaging system.This mesoscopic objective lens holds immense promise for advancing multi-wavelength imaging of large fields of view at high resolution.

Carbon efficiency evaluation method for urban energy system with multiple energy complementary

Urban energy systems(UESs)play a pivotal role in the consumption of clean energy and the promotion of energy cascade utilization.In the context of the construction and operation strategy of UESs with multiple complementary energy resources,a comprehensive assessment of the energy efficiency is of paramount importance.First,a multi-dimensional evaluation system with four primary indexes of energy utilization,environmental protection,system operation,and economic efficiency and 21 secondary indexes is constructed to comprehensively portray the UES.Considering that the evaluation system may contain a large number of indexes and that there is overlapping information among them,an energy efficiency evaluation method based on data processing,dimensionality reduction,integration of combined weights,and gray correlation analysis is proposed.This method can effectively reduce the number of calculations and improve the accuracy of energy efficiency assessments.Third,a demonstration project for a UES in China is presented.The energy efficiency of each scenario is assessed using six operational scenarios.The results show that Scenario 5,in which parks operate independently and investors build shared energy-storage equipment,has the best results and is best suited for green and low-carbon development.The results of the comparative assessment methods show that the proposed method provides a good energy efficiency assessment.This study provides a reference for the optimal planning,construction,and operation of UESs with multiple energy sources.

Distributed Stochastic Optimization with Compression for Non-Strongly Convex Objectives

We are investigating the distributed optimization problem,where a network of nodes works together to minimize a global objective that is a finite sum of their stored local functions.Since nodes exchange optimization parameters through the wireless network,large-scale training models can create communication bottlenecks,resulting in slower training times.To address this issue,CHOCO-SGD was proposed,which allows compressing information with arbitrary precision without reducing the convergence rate for strongly convex objective functions.Nevertheless,most convex functions are not strongly convex(such as logistic regression or Lasso),which raises the question of whether this algorithm can be applied to non-strongly convex functions.In this paper,we provide the first theoretical analysis of the convergence rate of CHOCO-SGD on non-strongly convex objectives.We derive a sufficient condition,which limits the fidelity of compression,to guarantee convergence.Moreover,our analysis demonstrates that within the fidelity threshold,this algorithm can significantly reduce transmission burden while maintaining the same convergence rate order as its no-compression equivalent.Numerical experiments further validate the theoretical findings by demonstrating that CHOCO-SGD improves communication efficiency and keeps the same convergence rate order simultaneously.And experiments also show that the algorithm fails to converge with low compression fidelity and in time-varying topologies.Overall,our study offers valuable insights into the potential applicability of CHOCO-SGD for non-strongly convex objectives.Additionally,we provide practical guidelines for researchers seeking to utilize this algorithm in real-world scenarios.

Effect of low-degree astigmatism on the objective visual quality

AIM:To evaluate the effect of low-degree astigmatism on objective visual quality through the Optical Quality Analysis System(OQAS).METHODS:This study enrolled 46 participants(aged 23 to 30y,90 eyes)with normal or corrected-to-normal vision.The cylindrical lenses(0,0.5,0.75,1.0,and 1.25 D)were placed at the axial direction(180°,45°,90°,and 135°)in front of the eyes with the best correction to form 16 types of regular low-degree astigmatism.OQAS was used to detect the objective visual quality,recorded as the objective scattering index(OSI),OQAS values at contrasts of 100%,20%,and 9%predictive visual acuity(OV100%,OV20%,and OV9%),modulation transfer function cut-off(MTFcut-off)and Strehl ratio(SR).The mixed effect linear model was used to compare objective visual quality differences between groups and examine associations between astigmatic magnitude and objective visual quality parameters.RESULTS:Apparent negative relationships between the magnitude of low astigmatism and objective visual quality were observed.The increase of OSI per degree of astigmatism at 180°,45°,90°,and 135°axis were 0.38(95%CI:0.35,0.42),0.50(95%CI:0.46,0.53),0.49(95%CI:0.45,0.54)and 0.37(95%CI:0.34,0.41),respectively.The decrease of MTFcut-off per degree of astigmatism at 180°,45°,90°,and 135°axis were-10.30(95%CI:-11.43,-9.16),-12.73(95%CI:-13.62,-11.86),-12.75(95%CI:-13.79,-11.70),and-9.97(95%CI:-10.92,-9.03),respectively.At the same astigmatism degree,OSI at 45°and 90°axis were higher than that at 0°and 135°axis,while MTFcut-off were lower.CONCLUSION:Low astigmatism of only 0.50 D can significantly reduce the objective visual quality.

A Systematic Literature Review of Machine Learning and Deep Learning Approaches for Spectral Image Classification in Agricultural Applications Using Aerial Photography

Recently,there has been a notable surge of interest in scientific research regarding spectral images.The potential of these images to revolutionize the digital photography industry,like aerial photography through Unmanned Aerial Vehicles(UAVs),has captured considerable attention.One encouraging aspect is their combination with machine learning and deep learning algorithms,which have demonstrated remarkable outcomes in image classification.As a result of this powerful amalgamation,the adoption of spectral images has experienced exponential growth across various domains,with agriculture being one of the prominent beneficiaries.This paper presents an extensive survey encompassing multispectral and hyperspectral images,focusing on their applications for classification challenges in diverse agricultural areas,including plants,grains,fruits,and vegetables.By meticulously examining primary studies,we delve into the specific agricultural domains where multispectral and hyperspectral images have found practical use.Additionally,our attention is directed towards utilizing machine learning techniques for effectively classifying hyperspectral images within the agricultural context.The findings of our investigation reveal that deep learning and support vector machines have emerged as widely employed methods for hyperspectral image classification in agriculture.Nevertheless,we also shed light on the various issues and limitations of working with spectral images.This comprehensive analysis aims to provide valuable insights into the current state of spectral imaging in agriculture and its potential for future advancements.

Objective Model Selection in Physics: Exploring the Finite Information Quantity Approach

Traditional methods for selecting models in experimental data analysis are susceptible to researcher bias, hindering exploration of alternative explanations and potentially leading to overfitting. The Finite Information Quantity (FIQ) approach offers a novel solution by acknowledging the inherent limitations in information processing capacity of physical systems. This framework facilitates the development of objective criteria for model selection (comparative uncertainty) and paves the way for a more comprehensive understanding of phenomena through exploring diverse explanations. This work presents a detailed comparison of the FIQ approach with ten established model selection methods, highlighting the advantages and limitations of each. We demonstrate the potential of FIQ to enhance the objectivity and robustness of scientific inquiry through three practical examples: selecting appropriate models for measuring fundamental constants, sound velocity, and underwater electrical discharges. Further research is warranted to explore the full applicability of FIQ across various scientific disciplines.

Real Time Thermal Image Based Machine Learning Approach for Early Collision Avoidance System of Snowplows

In an effort to reduce vehicle collisions with snowplows in poor weather conditions, this paper details the development of a real time thermal image based machine learning approach to an early collision avoidance system for snowplows, which intends to detect and estimate the distance of trailing vehicles. Due to the operational conditions of snowplows, which include heavy-blowing snow, traditional optical sensors like LiDAR and visible spectrum cameras have reduced effectiveness in detecting objects in such environments. Thus, we propose using a thermal infrared camera as the primary sensor along with machine learning algorithms. First, we curate a large dataset of thermal images of vehicles in heavy snow conditions. Using the curated dataset, two machine-learning models based on the modified ResNet architectures were trained to detect and estimate the trailing vehicle distance using real-time thermal images. The trained detection network was capable of detecting trailing vehicles 99.0% of the time at 1500.0 ft distance from the snowplow. The trained trailing distance network was capable of estimating distance with an average estimation error of 10.70 ft. The inference performance of the trained models is discussed, along with the interpretation of the performance.

Patterns of Interactions of the Complex City System:Emotional Urban Objects as Triggering Agents-A Secondary Publication

This article presents an analysis of the patterns of interactions resulting from the positive and negative emotional events that occur in cities,considering them as complex systems.It explores,from the imaginaries,how certain urban objects can act as emotional agents and how these events affect the urban system as a whole.An adaptive complex systems perspective is used to analyze these patterns.The results show patterns in the processes and dynamics that occur in cities based on the objects that affect the emotions of the people who live there.These patterns depend on the characteristics of the emotional charge of urban objects,but they can be generalized in the following process:(1)immediate reaction by some individuals;(2)emotions are generated at the individual level which begins to generalize,permuting to a collective emotion;(3)a process of reflection is detonated in some individuals from the reading of collective emotions;(4)integration/significance in the community both at the individual and collective level,on the concepts,roles and/or functions that give rise to the process in the system.Therefore,it is clear that emotions play a significant role in the development of cities and these aspects should be considered in the design strategies of all kinds of projects for the city.Future extensions of this work could include a deeper analysis of specific emotional events in urban environments,as well as possible implications for urban policy and decision making.

Research on the Relationship between the School-Running Characteristics of Private Colleges and Universities and the Development Objectives of the Government

The development objectives of the Chinese government have a guiding effect on the school-running characteristics of private colleges and universities.This paper explores the relationship between the characteristics of private colleges and universities and the development objectives of the provincial government,using Jiangsu Province as a case study.All the schools have the consciousness of fully considering the development objectives of Jiangsu Province when formulating the school-running characteristics.Their characteristics all contain some training methods,training courses,or institutional construction aiming at the development objectives.Most universities can support the government’s objectives on employment and innovation.Only a third of the schools provide government support for science research.Private colleges and universities should make full use of the free and flexible advantages of private education,combine them with the continuous changes of policies and markets,and create clear,scientific,and dynamic school-running characteristics,in order to achieve long-term development.

Objective System and Coordination Mechanism Design for “Multi-Planning System Integration”

One of the hot issues to realize the multi-planning system integration is to explore the inter-planning coordination mechanism breaking current technical and system restrictions. The essence of planning disintegration is the disconnection of their objective system, indicator system, and spatial coordinate system. Few studies have been conducted on this issue. This paper analyzes the manifestations and causes of the "three-system dissociation," and proposes to establish a new objective system. In addition, it proposes to strengthen the connection design, aiming to explore effective ways to realize inter-planning connection and coordination.

Eclipse计划系统MU Objective工具在鼻咽癌容积调强放射治疗计划中的应用研究

目的:探讨Varian Eclipse计划系统MU Objective工具在鼻咽癌容积调强放射治疗(VMAT)计划中的应用,旨在保证治疗计划质量的同时降低治疗计划的机器跳数(MU)。方法:选取已接受容积调强放射治疗技术的21例鼻咽癌患者,在未使用MU Objective工具的情况下给每例患者设计治疗参考计划(MU_(ref));将使用MU Objective工具对MU_(ref)进行重新优化,分别设置MU_(ref)的MU的30%、50%、70%、90%和120%,分别命名为MU_(30%)、MU_(50%)、MU_(70%)、MU_(90%)和MU_(120%)。将治疗计划MU_(30%)、MU_(50%)、MU_(70%)、MU_(90%)和MU_(120%)分别与MU_(ref)进行配对t检验统计分析,比较两种治疗计划的靶区、危及器官(OAR)剂量分布和计划的MU。结果:使用MU Objective工具对参考计划优化MU后,与参考计划相比部分靶区和OAR剂量体积参数差异虽有统计学意义,但无临床意义。治疗计划参数为MU_(30%)、MU_(50%)、MU_(70%)和MU_(90%)时,与MU_(ref)比较计划MU平均分别减少21.5%、19.5%、16.6%和8%,差异有统计学意义(t=9.652,t=8.843,t=8.963,t=11.323;P<0.05)。在MU_(120%)时,治疗计划MU平均增加1.7%,但未显著提高靶区剂量覆盖。结论:对于鼻咽癌VMAT计划,使用Eclipse计划系统的MU Objective工具在减少计划MU的同时可获得与参考计划相似的剂量分布。MU Objective工具可作为鼻咽癌或其他部位VMAT计划的常规使用工具,以保证计划质量同时减少放射治疗计划的MU。

Distributed Parallelization of a Global Atmospheric Data Objective Analysis System

It is difficult to parallelize a subsistent sequential algorithm. Through analyzing the sequential algorithm of a Global Atmospheric Data Objective Analysis System, this article puts forward a distributed parallel algorithm that statically distributes data on a massively parallel processing (MPP) computer. The algorithm realizes distributed parailelization by extracting the analysis boxes and model grid point Iatitude rows with leaped steps, and by distributing the data to different processors. The parallel algorithm achieves good load balancing, high parallel efficiency, and low parallel cost. Performance experiments on a MPP computer arc also presented.

Hierarchical Algorithms of Large-Scale Systems with Nonseparable Multiobjective

A class of large-scale hierarchical control systems is considered, the overall objective function is a nonlinear and nonseparable function of multiple quadratic performance indices.The separation strategy of the multiobjective optimization technique and the three-level objective coordination method are applied to the large -sacle systems, and a four-level hierarchical algorithms of optimization control is obtained.

Subtle skills: Using objective structured clinical examinations to assess gastroenterology fellow performance in system based practice milestones

BACKGROUND System based practice(SBP) milestones require trainees to effectively navigate the larger health care system for optimal patient care. In gastroenterology training programs, the assessment of SBP is difficult due to high volume, high acuity inpatient care, as well as inconsistent direct supervision. Nevertheless,structured assessment is required for training programs. We hypothesized that objective structured clinical examination(OSCE) would be an effective tool for assessment of SBP.AIM To develop a novel method for SBP milestone assessment of gastroenterology fellows using the OSCE.METHODS For this observational study, we created 4 OSCE stations: Counseling an impaired colleague, handoff after overnight call, a feeding tube placement discussion, and giving feedback to a medical student on a progress note. Twentysix first year fellows from 7 programs participated. All fellows encountered identical case presentations. Checklists were completed by trained standardized patients who interacted with each fellow participant. A report with individual and composite scores was generated and forwarded to program directors to utilize in formative assessment. Fellows also received immediate feedback from a faculty observer and completed a post-session program evaluation survey.RESULTS Survey response rate was 100%. The average composite score across SBP milestones for all cases were 6.22(SBP1), 4.34(SBP2), 3.35(SBP3), and 6.42(SBP4)out of 9. The lowest composite score was in SBP 3, which asks fellows to advocate for cost effective care. This highest score was in patient care 2, which asks fellows to develop comprehensive management plans. Discrepancies were identified between the fellows’ perceived performance in their self-assessments and Standardized Patient checklist evaluations for each case. Eighty-seven percent of fellows agreed that OSCEs are an important component of their clinical training,and 83% stated that the cases were similar to actual clinical encounters. All participating fellows stated that the immediate feedback was "very useful." One hundred percent of the fellows stated they would incorporate OSCE learning into their clinical practice.CONCLUSION OSCEs may be used for standardized evaluation of SBP milestones. Trainees scored lower on SBP milestones than other more concrete milestones. Training programs should consider OSCEs for assessment of SBP.

SELECTION OF OBJECTIVE FUNCTIONS AND APPLICATION OF GENETIC ALGORITHMS IN DAMPING DESIGN OF PIPE SYSTEM

The vibration failure of pipe system of aeroengine seriously influences the safety of aircraft.Its damping design is determined by the selection of the design target,method and their feasibility.Five objective functions for the vibration design of a pipeline or pipe system are introduced,namely,the frequency,amplitude,transfer ratio,curvature and deformation energy as options for the optimization process.The genetic algorithms(GA)are adopted as the opti- mization method,in which the selection of the adaptive genetic operators and the method of implementation of the GA process are crucial.The optimization procedure for all the above ob- jective functions is carried out using GA on the basis of finite element software-MSC/NASTRAN. The optimal solutions of these functions and the stress distribution on the structure are calculated and compared through an example,and their characteristics are analyzed.Finally we put forward two new objective functions,curvature and deformation energy for pipe system optimization.The calculations show that using the curvature as the objective function can reflect the case of minimal stress,and the optimization results using the deformation energy represent lesser and more uni- form stress distribution.The calculation results and process showed that the genetic algorithms can effectively implement damping design of engine pipelines and satisfy the efficient engineering design requirement.

Accounting Objectives and Reporting System Construction of Managerial Accounting in China

The purpose of this paper is to propose an innovation system of managerial accounting reports, which is actually on the basis of accounting objectives. On the one hand, as managerial accounting is one important branch of accounting(the other important branch is financial accounting), some of its characters should be closely connected with accounting. On the other hand, managers need managerial accounting information for enterprise operation(especially for internal management control) decisions, so, managerial accounting should also be in accordance with the enterprise's operation and its management control. Therefore, combined with the existed research of accounting(especially financial accounting research) and for the development requirement of Chinese enterprises, this paper will mainly discuss the relation between accounting objectives and managerial accounting's system and put forward an idea of constructing an applicable reporting system of managerial accounting based on the operation mode in Chinese modern enterprises. This study will develop the accounting reports research(including external reports and internal reports) both in the field of theory and that of practice.

Objective Identification and Climatic Characteristics of Heavy-Precipitation Northeastern China Cold Vortexes

The northeastern China cold vortex(NCCV)plays an important role in regional rainstorms over East Asia.Using the National Centers for Environmental Prediction Final reanalysis dataset and the Global Precipitation Measurement product,an objective algorithm for identifying heavy-precipitation NCCV(HPCV)events was designed,and the climatological features of 164 HPCV events from 2001 to 2019 were investigated.The number of HPCV events showed an upward linear trend,with the highest frequency of occurrence in summer.The most active region of HPCV samples was the Northeast China Plain between 40°–55°N.Most HPCV events lasted 3–5 days and had radii ranging from 250 to 1000 km.The duration of HPCV events with larger sizes was longer.About half of the HPCV events moved into(moved out of)the definition region(35°–60°N,115°–145°E),and half initiated(dissipated)within the region.The initial position was close to the western boundary of the definition region,and the final position was mainly near the eastern boundary.The locations associated with the precipitation were mostly concentrated within 2000 km southeast of the HPCV systems,and they were farther from the center in the cold season than in the warm season.

Multi‐objective particle swarm optimisation of complex product change plan considering service performance

Design change is an inevitable part of the product development process.This study proposes an improved binary multi‐objective PSO algorithm guided by problem char-acteristics(P‐BMOPSO)to solve the optimisation problem of complex product change plan considering service performance.Firstly,a complex product multi‐layer network with service performance is established for the first time to reveal the impact of change effect propagation on the product service performance.Secondly,the concept of service performance impact(SPI)is defined by decoupling the impact of strongly associated nodes on the service performance in the process of change affect propagation.Then,a triple‐objective selection model of change nodes is established,which includes the three indicators:SPI degree,change cost,and change time.Furthermore,an integer multi‐objective particle swarm optimisation algorithm guided by problem characteristics is developed to solve the model above.Experimental results on the design change problem of a certain type of Skyworth TV verify the effectiveness of the established optimisation model and the proposed P‐BMOPSO algorithm.

Realtime Object Detection Through M-ResNet in Video Surveillance System

Object detection plays a vital role in the video surveillance systems.To enhance security,surveillance cameras are now installed in public areas such as traffic signals,roadways,retail malls,train stations,and banks.However,monitor-ing the video continually at a quicker pace is a challenging job.As a consequence,security cameras are useless and need human monitoring.The primary difficulty with video surveillance is identifying abnormalities such as thefts,accidents,crimes,or other unlawful actions.The anomalous action does not occur at a high-er rate than usual occurrences.To detect the object in a video,first we analyze the images pixel by pixel.In digital image processing,segmentation is the process of segregating the individual image parts into pixels.The performance of segmenta-tion is affected by irregular illumination and/or low illumination.These factors highly affect the real-time object detection process in the video surveillance sys-tem.In this paper,a modified ResNet model(M-Resnet)is proposed to enhance the image which is affected by insufficient light.Experimental results provide the comparison of existing method output and modification architecture of the ResNet model shows the considerable amount improvement in detection objects in the video stream.The proposed model shows better results in the metrics like preci-sion,recall,pixel accuracy,etc.,andfinds a reasonable improvement in the object detection.

Objective Reduction Solutions to Higher-Order Boussinesq System in (2+1)-Dimensions

With the help of an objective reduction approach （ORA）, abundant exact solutions of （2＋1）-dimensional higher-order Boussinesq system （including some hyperboloid function solutions, trigonometric function solutions, and a rational function solution） are obtained. It is shown that some novel soliton structures, like single linearity soliton structure, breath soliton structure, single linearity y-periodic solitary wave structure, libration dromion structure, and kink-like multisoliton structure with actual physical meaning exist in the （2＋1）-dimensional higher-order Boussinesq system.