Objective: Contribute to improving care for prostate cancer patients in Cote d’Ivoire by identifying the average time before the development of the hormone-resistance and inherent therapeutic strategies. Patients and...Objective: Contribute to improving care for prostate cancer patients in Cote d’Ivoire by identifying the average time before the development of the hormone-resistance and inherent therapeutic strategies. Patients and Method: It was a retro and prospective study over three years performed at the University Teaching Hospital of Treichville in Abidjan. 84 patients with metastatic prostate adenocarcinoma and resistant to hormone therapy were involved in the study. The analysis of clinical records enabled us to integrate different parameters in our study. Results: Our patients were relatively young (an average age of 61 years) and most of them belonged to the middle socio-economic class (50%). The resistance occurred within an average period of 9 months. The mixing of Docetaxel and Prednisone chemotherapy was the most used method of treatment (70% of cases). However, few patients (9.5%) received Abiraterone Acetate. Digestive and hematologic toxicities were noticed but they could be controlled by inherent treatment or disappear spontaneously. After nine months of treatment, 54.24% of patients who received specific treatment were alive, but high rates of mortality were observed as for patients who were only treated symptomatically. Conclusion: The relatively short average time before the development of hormone-resistance shows the aggressiveness of prostate adenocarcinoma from black Africans. The main therapeutic standard in our context remains Taxane-based chemotherapy with a good and fair tolerance.展开更多
This paper deals with the distributive characteristics of the occurrence time of earthquakes with respect to the aftershock sequences of strong earthquakes. The distribution of lunar and solar local hour angles at the...This paper deals with the distributive characteristics of the occurrence time of earthquakes with respect to the aftershock sequences of strong earthquakes. The distribution of lunar and solar local hour angles at the time of commencement of moderate and strong aftershocks indicates that the time of commencement of moderate and strong aftershocks is modulated by the positions of the sun and moon and then the earthquake restrained time zones exists also. In this paper the differences of earthquake restrained time zones between the preshock sequences and the aftershock sequences are compared, and the possible mechanism is analyzed preliminarily. And the possible maximum scope of accuracy in predicting the occurrence time of an earthquake is determined as well.展开更多
文摘Objective: Contribute to improving care for prostate cancer patients in Cote d’Ivoire by identifying the average time before the development of the hormone-resistance and inherent therapeutic strategies. Patients and Method: It was a retro and prospective study over three years performed at the University Teaching Hospital of Treichville in Abidjan. 84 patients with metastatic prostate adenocarcinoma and resistant to hormone therapy were involved in the study. The analysis of clinical records enabled us to integrate different parameters in our study. Results: Our patients were relatively young (an average age of 61 years) and most of them belonged to the middle socio-economic class (50%). The resistance occurred within an average period of 9 months. The mixing of Docetaxel and Prednisone chemotherapy was the most used method of treatment (70% of cases). However, few patients (9.5%) received Abiraterone Acetate. Digestive and hematologic toxicities were noticed but they could be controlled by inherent treatment or disappear spontaneously. After nine months of treatment, 54.24% of patients who received specific treatment were alive, but high rates of mortality were observed as for patients who were only treated symptomatically. Conclusion: The relatively short average time before the development of hormone-resistance shows the aggressiveness of prostate adenocarcinoma from black Africans. The main therapeutic standard in our context remains Taxane-based chemotherapy with a good and fair tolerance.
文摘This paper deals with the distributive characteristics of the occurrence time of earthquakes with respect to the aftershock sequences of strong earthquakes. The distribution of lunar and solar local hour angles at the time of commencement of moderate and strong aftershocks indicates that the time of commencement of moderate and strong aftershocks is modulated by the positions of the sun and moon and then the earthquake restrained time zones exists also. In this paper the differences of earthquake restrained time zones between the preshock sequences and the aftershock sequences are compared, and the possible mechanism is analyzed preliminarily. And the possible maximum scope of accuracy in predicting the occurrence time of an earthquake is determined as well.
