Optimization on bicriterion policies for M/G/1 system with second optional service

We compare the optimal operating cost of the two bicriterion policies, <p,T> and <p,N>, for an M/G/1 queueing system with second optional service, in which the length of the vacation period is randomly controlled either by the number of arrivals during the idle period or by a timer. After all the customers are served in the queue exhaustively, the server immediately takes a vacation and may operate <p,T> policy or <p,N> policy. For the two bicriterion policies, the total average cost function per unit time is developed to search the optimal stationary operating policies at a minimum cost. Based upon the optimal cost the explicit forms for joint optimum threshold values of (p,T) and (p,N) are obtained.

弹性退休制度下谁更愿意延迟退休?——基于Option Value模型的微观模拟

人口老龄化背景下延迟退休年龄、建立弹性退休制度是大势所趋。养老金激励是弹性退休制度的重要内容。建立期权价值模型和养老金给付及奖惩因子模型,基于中国家庭收入调查项目(CHIP2018)的数据,对不同特征人群的养老金峰值、期权价值、内部报酬率进行模拟。研究发现:养老金总财富随退休年龄“先增后减”,男性的峰值年龄早于女性;引入养老金“奖惩”机制有助于提高最优退休年龄,激励劳动者延迟退休;考虑闲暇偏好的异质性,男性参保者更倾向于早退休,而女性参保者特别是女性较高收入群体更愿意延迟退休;厌恶风险的参保者更有可能选择早退休。建议尽早建立弹性退休年龄政策体系,增加劳动者的选择权和制度灵活性;引入精算调节因子构建养老金奖惩机制,完善养老保险待遇计发办法。

基于IUV_5G Option3X架构网络规划与部署设计

本文基于IUV_5G Option3X架构,详细阐述了5G网络的规划与部署设计过程。首先介绍了5G NSA组网架构的背景和优势,然后深入探讨了IUV_5G全网部署与优化虚拟仿真平台的功能和应用。重点描述了核心网、无线网和承载网的部署过程,包括设备部署、数据配置和线路连接等具体步骤。通过业务验证确认了网络部署的成功,并对5G技术的未来发展进行了展望。

基于互信息优化的Option-Critic算法

时序抽象作为分层强化学习的重要研究内容,允许分层强化学习智能体在不同的时间尺度上学习策略,可以有效解决深度强化学习难以处理的稀疏奖励问题。如何端到端地学习到优秀的时序抽象策略一直是分层强化学习研究面临的挑战。Option-Critic(OC)框架在Option框架的基础上,通过策略梯度理论,可以有效解决此问题。然而,在策略学习过程中,OC框架会出现Option内部策略动作分布变得十分相似的退化问题。该退化问题影响了OC框架的实验性能,导致Option的可解释性变差。为了解决上述问题,引入互信息知识作为内部奖励,并提出基于互信息优化的Option-Critic算法(Option-Critic Algorithm with Mutual Information Optimization,MIOOC)。MIOOC算法结合了近端策略Option-Critic(Proximal Policy Option-Critic,PPOC)算法,可以保证下层策略的多样性。为了验证算法的有效性,把MIOOC算法和几种常见的强化学习方法在连续实验环境中进行对比实验。实验结果表明,MIOOC算法可以加快模型学习速度,实验性能更优,Option内部策略更有区分度。

Pricing Catastrophe Options with Credit Risk in a Regime-Switching Model

In this paper,we consider the price of catastrophe options with credit risk in a regime-switching model.We assume that the macroeconomic states are described by a continuous-time Markov chain with a finite state space.By using the measure change technique,we derive the price expressions of catastrophe put options.Moreover,we conduct some numerical analysis to demonstrate how the parameters of the model affect the price of the catastrophe put option.

Unroofed coronary sinus,left-sided superior vena cava and mitral insufficiency:A case report and review of the literature

BACKGROUND Unroofed coronary sinus(UCS)is a rare subtype of atrial septal defect.It is frequently associated with a persistent left superior vena cava and is often part of a more intricate cardiac malformation.CASE SUMMARY This report describes a rare case of an adolescent patient with UCS featuring atrial situs solitus,absence of the right superior vena cava and a persistent left superior vena cava draining into the left atrium consistent with total unroofing of the coronary sinus.This was associated with concurrent severe mitral insufficiency secondary to redundant and prolapsing leaflets,and a substantial left-to-right shunt across the coronary sinus orifice.A comprehensive examination of the existing literature is included,shedding light on the diagnostic challenges of UCS and describing the available surgical options within the context of mitral valve surgery.CONCLUSION UCS is a complex condition requiring careful consideration of associated anomalies and a tailored surgical approach.

Exploring the limited use of transdermal medications in psychiatry:Challenges and potential solutions

Transdermal medications are an useful yet underutilized tool in the field of psychiatry.Despite numerous advantages of using this route of medication delivery,transdermal medications remain less popular compared to other routes of medication administration such as oral and intramuscular routes in the management of various psychiatric conditions.In this editorial,we examine the advantages of transdermal medications with a brief overview of transdermal being used in psychiatry and other medical specialties.We discuss the factors that play a role in their limited usage in psychiatry.We highlight certain patient categories who can specifically benefit from them and discuss potential solutions that can broaden the perspective of treating clinicians making this an intriguing avenue in the field of psychiatry.

Modeling the Spatio-Temporal Dynamics of Local Context for a Contextualized Diffusion of Agroecological Intensification Options in Niger

Spatio-temporal variability and dynamics in Sahelian agro-pastoral zones make each local situation a special case. These specificities must be considered to guide the dissemination of agricultural options with a view to sustainable development. The territorial scale of municipalities is not sufficient for this necessary contextualization;the scale of the “village terroir” seems to be a better option. This is the hypothesis we put forward in the framework of the Global Collaboration for Resilient Food Systems program (CRFS), i.e. local context is spatially defined by village terroir. The study is based on data collected through participatory mapping and surveys in “village terroirs” in three regions of Niger (Maradi, Dosso and Tillabéri). Then the links between farm managers and their cultivated land, as well as the spatio-temporal dynamics of local context are analyzed. This study provides evidence of the existence and functional usefulness of the village terroir for farmers, their land management and their activities. It demonstrates the usefulness of contextualizing agricultural options at this scale. Their analysis elucidates the links between “terroirs village” and the specific functioning of the agrosocio-ecosystems acting on each of them, thus laying the systemic and geographical foundations for a model of the spatio- temporal dynamics of “village terroirs”. This initial work has opened up new perspectives in modeling and sustainable development.

Type 2 diabetes in children and adolescents:Exploring the disease heterogeneity and research gaps to optimum management

Over the past 20 years,the incidence and prevalence of type 2 diabetes mellitus(T2DM)in children and adolescents have increased,particularly in racial and ethnic minorities.Despite the rise in T2DM in children and adolescents,the pathophysiology and progression of disease in this population are not clearly understood.Youth-onset T2DM has a more adverse clinical course than is seen in those who develop T2DM in adulthood or those with T1DM.Furthermore,the available therapeutic options are more limited for children and adolescents with T2DM compared to adult patients,mostly due to the challenges of implementing clinical trials.A better understanding of the mechanisms underlying the development and aggressive disease phenotype of T2DM in youth is important to finding effective prevention and management strategies.This review highlights the key evidence about T2DM in children and adolescents and its current burden and challenges both in clinical care and research activities.

Research on Value Evaluation Method of Investment Project Based on Fuzzy Composite Real Options

Venture capital investments are characterized by high input,high yield,and high risk.Due to the complexity of the market environment,stage-by-stage investment is becoming increasingly important.Traditional evaluation methods like comparison,proportion,maturity,internal rate of return,scenario analysis,decision trees,and net present value cannot fully consider the uncertainty and stage characteristics of the project.The fuzzy real options method addresses this by combining real option theory,fuzzy number theory,and composite option theory to provide a more accurate and objective evaluation of Public-Private Partnership(PPP)projects.It effectively considers the interaction of options and the ambiguity of project parameters,making it a valuable tool for project evaluation in the context of venture capital investment.

Mitigation Options for Methane, Nitrous Oxide and NitricOxide Emissions from Agricultural Ecosystems

An experimental study on mitigation of greenhouse gas (CH4, N2O and NO) emission has been conducted in a typical cropping system of Southeast China for 4 years. By simultaneous measurement, the CH4, N2O and NO emission fluxes from rice-wheat rotation fields, effects of fertilization, water management, temperature and soil moisture were investigated. Temperature, fertilization and water status were found to be the key factors to regulate CH4, N2O and NO emis-sions. Based on the experimental results, some agricultural measures were recommended as techni-cal options to mitigate greenhouse gas emissions from rice-wheat rotation ecosystems. These miti-gation measures are reducing mineral N input, coupling organic manure with chemical fertilizers, applying fertilizers which release available N slowly during periods with intensive plant activity, and applying dry fermented organic manure and well management of water and fertilizer. Key words Mitigation options - Emission - Greenhouse gases - Ecosystems This study was supported by projects “ Experimental and Modeling Study on N2O Emission from the Rice-Wheat Rotation Fields of Southeast China” and “ Experimental and Modeling Study on NO Emission from Croplands” , which were granted by the National Natural Science Foundation of China, the State Key Fundamental Research Project “ Predicting the Future (20–50 years) Trend of Environmental Change in China”, and the project of Chinese Academy of Sciences “ Theory and Methodology on Air Pollution Prediction”.Thanks are due to Professor Zhang Wen, Dr. Bai Jianhui, Mr. Gong Yanbang, Mrs. Luo Dongmei and Mr. Liu Guangren from the Institute of Atmospheric Physics, Chinese Academy of Sciences for their help in experiments.

Nutrient Cycling and Balance in Red Soil Agroecosystem and Their Management

An experiment was conducted in a red soil derived from Quaternary red clay in the Ecological ExperimentStation of Red Soil, the Chinese Academy of Sciences, located in Yingtan (28° 15′ 30″ N, 116° 55′ 30″E), Jiangxi Province. The results show that the major ways of nutrient loss are leaching and nitrogenvolatilization. Rationalizing crop distribution, stimulating nutrient recycling, and improving internal nutrientflow are effective measures to decrease nutrient loss and to promote nutrient utilization efficiency. Theimportant ways of regulating nutrient cycling and balance in the agroecosystem of the red soil are to establishoptimal eco-agricultural models, practice balanced fertilization and combine the cropping system with thelivestock system.

Studies on Technique of Reducing Methane Emission in a Rice-Duck Ecological System and the Evaluation of Its Economic Significance

The rice-duck ecological system is one of the major practices of the traditional Chinese agriculture. A study on the effect of reducing methane emission using this practice provided theoretical and practical basis for further development and utilization of this classical agricultural technique. The effect of reducing methane emission and the economic benefits of rice-duck ecological system were studied by carrying out a field experiment and by using economic methodology. The daily variation of CH4 emission in late rice paddy field was basically consistent with the daily variation of atmospheric temperature. The highest emission occurred at the full tillering stage of late rice with a rate of 24.1 or 32.2 or 40.5 mg m^-2 h^-1 in no-tillage area with duck and no-tillage area without duck and conventional-tillage area without duck, respectively. The inhibition of methane emission was apparently effective in the rice-duck ecological system during the initial tillering stage and the full tillering stage. Compared to the no-tillage area without duck, methane emission decreased by 2.333 g m^-2. Compared to the conventional-tillage area without duck, methane emission decreased by 4.723 g m^-2. During the production period of late rice, the amount of methane emission in no-tillage area with duck was 3.373 g m^-2 lesser than that of no-tillage area without duck, and 5.59 g m^-2 less than that of conventional-tillage without duck area. The economic significance was analyzed. Farmers adopting the rice-duck ecological system obtained 2 166 and 4 207 RMB yuan ha^-1 more income than those who adopted a no-tillage without duck technique or conventional-tillage without duck technique, respectively. In addition to the reduction of the environmental pollution by methane emission, the farmers who adopted the rice-duck ecological system achieved economic benefits of 5 000 RMB yuan ha^-1, which was 2 206 and 4 274 RMB yuan ha^-1 more than those who adopted a no-tillage without duck technique and a conventional-tillage without duck technique, respectively. The rice-duck ecological system not only increased the economic benefits for farmers, but also reduced methane emission in rice paddy field. A sustainable agricultural production mode was formed.

FUNCTIONAL ANALYSIS METHOD FOR THE M/G/1 QUEUEING MODEL WITH OPTIONAL SECOND SERVICE

By studying the spectral properties of the underlying operator corresponding to the M/G/1 queueing model with optional second service we obtain that the time-dependent solution of the model strongly converges to its steady-state solution. We also show that the time-dependent queueing size at the departure point converges to the corresponding steady-state queueing size at the departure point.

Sequencing of systemic treatment for hepatocellular carcinoma: Second line competitors

During the last decades,further knowledge of hepatocellular carcinoma(HCC)molecular mechanisms has led to development of effective systemic treatments including tyrosine kinase inhibitors(TKIs)and immunotherapy.In this review,we describe first and second line systemic treatment options for advanced HCC.Several trials have evaluated new drugs for the treatment of HCC patients:In first line,lenvatinib resulted non-inferior to sorafenib and it can be used as alternative,even in the lack of evidence for sequential treatment options in second line after lenvatinib.Recently,atezolizumab plus bevacizumab have shown superiority over sorafenib in first-line.Sorafenib-regorafenib sequential administration in selected patients has opened a new paradigm of treatment in advanced HCC with a life expectancy exceeding two years.Other TKIs for second line treatment include cabozantinib and ramucirumab(specifically for patients with Alpha-fetoprotein values≥400 ng/mL).The combination of TKIs with immunotherapy may represent a big step forward for these patients in the near future.

Evaluation of COSMO-RS for solid–liquid equilibria prediction of binary eutectic solvent systems

For the design of eutectic solvents(ESs,usually also known as deep eutectic solvents),the prediction of the solid–liquid equilibria(SLE)between candidate components is of primary relevance.In the present work,the SLE prediction of binary eutectic solvent systems by the COSMO-RS model is systematically evaluated,thereby examining the applicability of this method for ES design.Experimental SLE of such systems are first collected exhaustively from the literature,following which COSMO-RS SLE calculations are accordingly carried out.By comparing the experimental and predicted eutectic points(eutectic temperature and eutectic composition)of the involved systems,the effects of salt component conformer and COSMO-RS parameterization as well as the applicability for different types of components(specifically the second component paired with the first salt one)are identified.The distinct performances of COSMO-RS SLE prediction for systems involving different types of components are further interpreted from the non-ideality and fusion enthalpy point of view.

Adaptation to Climate Change in the Pastoral and Agropastoral Systems of Borana, South Ethiopia: Options and Barriers

The pastoral and agropastoral systems of the Borana in southern Ethiopia are highly vulnerable to climate change and its impacts. Assistance to enable these smallholders to successfully adapt to future climate change in locally relevant ways can be usefully informed by the analysis and better understanding of past and ongoing adaptation. We conducted farm household surveys, focus group discussions, expert consultations and secondary data collation in 2012 in the Borana. The study employed a combination of Pressure-State-Response (PSR) framework to analyse how climate change put pressure on pastoral and agropastoral farming systems and livelihoods, and Pelling’s (2011) typological framework to analyse local adaptation responses. Results showed that pastoral and agropastoral households, their communities and institutions adopted a wide range of adaptation options primarily through adjusting their farming practices and diversifying into non-pastoral livelihoods. The smallholders primarily pursued a resilience approach to adaptation with short term goals intended to avoid system disruptions instead of long-term transformational approaches that significantly address the root causes of vulnerability. A range of barriers constrained local adaptive capacity and shaped routes for adaptation. Adaptation pathways that address critical barriers to adapt, integrate indigenous institutions into adaptation and link adaptation with local development process are necessary to bring long-term and non-marginal, major changes that reduce vulnerability and ensure co-benefit of improving livelihoods.

Evaluating Sensitivity to Different Options and Parameterizations of a Coupled Air Quality Modelling System over Bogotá, Colombia. Part I: WRF Model Configuration

Meteorological inputs are of great importance when implementing an air quality prediction system. In this contribution, the Weather Research and Forecast (WRF-ARW) model was used to compare the performance of the different cumulus, microphysics and Planet Boundary Layer parameterizations over Bogotá, Colombia. Surface observations were used for comparison and the evaluated meteorological variables include temperature, wind speed and direction and relative humidity. Differences between parameterizations were observed in meteorological variables and Betts-Miller-Janjic, Morrison 2-moment and BouLac schemes proved to be the best parameterizations for cumulus, microphysics and PBL, respectively. As a complement to this study, a WRF-Large Eddy Simulation was conducted in order to evaluate model results with finer horizontal resolution for air quality purposes.

Fundamental Options for Designing Transmission Systems Supplying Metropolitan Centers

Transgression networks in metropolitan centers need to supply a large quantity of power in a reliable manner to vital loads that are located within. A transmission network supplying such an important area must have a high standard of reliability. Therefore, those transmission systems require a special form of redundancy in order to prevent sustained outages after severe contingencies such as multiple faults. This paper outlines different forms of redundancy, and the fundamental options for designing a metropolitan network based on different forms of redundancy are illustrated. Relative merits and drawbacks of network designs based on each form of redundancy are also shown.

OPTIONAL AND PREDICTABLE PROJECTIONS OF SET-VALUED MEASURABLE PROCESSES

In this paper,the optional and predictable projections of set-valued measurable processes are studied.The existence and uniqueness of optional and predictable projections of set-valued measurable processes are proved under proper circumstances.