In this study,a novel hybrid Water Cycle Moth-Flame Optimization(WCMFO)algorithm is proposed for multilevel thresholding brain image segmentation in Magnetic Resonance(MR)image slices.WCMFO constitutes a hybrid betwee...In this study,a novel hybrid Water Cycle Moth-Flame Optimization(WCMFO)algorithm is proposed for multilevel thresholding brain image segmentation in Magnetic Resonance(MR)image slices.WCMFO constitutes a hybrid between the two techniques,comprising the water cycle and moth-flame optimization algorithms.The optimal thresholds are obtained by maximizing the between class variance(Otsu’s function)of the image.To test the performance of threshold searching process,the proposed algorithm has been evaluated on standard benchmark of ten axial T2-weighted brain MR images for image segmentation.The experimental outcomes infer that it produces better optimal threshold values at a greater and quicker convergence rate.In contrast to other state-of-the-art methods,namely Adaptive Wind Driven Optimization(AWDO),Adaptive Bacterial Foraging(ABF)and Particle Swarm Optimization(PSO),the proposed algorithm has been found to be better at producing the best objective function,Peak Signal-to-Noise Ratio(PSNR),Standard Deviation(STD)and lower computational time values.Further,it was observed thatthe segmented image gives greater detail when the threshold level increases.Moreover,the statistical test result confirms that the best and mean values are almost zero and the average difference between best and mean value 1.86 is obtained through the 30 executions of the proposed algorithm.Thus,these images will lead to better segments of gray,white and cerebrospinal fluid that enable better clinical choices and diagnoses using a proposed algorithm.展开更多
Segmentation has been an effective step that needs to be done before the classification or detection of an anomaly like Alzheimer’s on a brain scan.Segmentation helps detect pixels of the same intensity or volume and...Segmentation has been an effective step that needs to be done before the classification or detection of an anomaly like Alzheimer’s on a brain scan.Segmentation helps detect pixels of the same intensity or volume and group them together as one class or region,where in that particular region of interest(ROI)can be concentrated on,rather than focusing on the entire image.In this paper White Matter Hyperintensities(WMH)is taken as a strong biomarker that supports and determines the presence of Alzheimer’s.As thefirst step a proper segmentation of the lesions has to be carried out.As pointed out in various other research papers,when the WMH area is very small or in places like the Septum Pellucidum the detection of the lesion is hard tofind.To overcome such problem areas a very optimized and accurate Threshold would be required to have a precise segmentation to detect the area of localization.This would help in proper detection and classification of the Anomaly.In this paper an elaborate comparison of various thresholding techniques has been done for segmentation.A novel idea for detection of Alzheimer’s has been presented in this paper,which encompasses the effectiveness of an optimized and adaptive technique.The Unet architecture has been taken as the baseline model with an adaptive kernel model embedded within the architecture.Various state-of-the-art technologies have been used with the dataset and a comparative study has been presented with the current architecture used in the paper.The lesion segmentation in narrow areas has accurately been detected compared to the other models and the number of false positives has been reduced to a great extent.展开更多
根据频谱扩展-压缩(spectrum spread and compression,SSC)移频干扰信号和回波信号时频分布特性的差异,提出一种基于广义S变换和Tsallis交叉熵阈值分割的干扰抑制方法。分析了SSC移频干扰的干扰原理和干扰信号经过解线调后的信号形式,...根据频谱扩展-压缩(spectrum spread and compression,SSC)移频干扰信号和回波信号时频分布特性的差异,提出一种基于广义S变换和Tsallis交叉熵阈值分割的干扰抑制方法。分析了SSC移频干扰的干扰原理和干扰信号经过解线调后的信号形式,并利用时频聚焦性较好的广义S变换获取接收信号经过解线调后的时频图像,根据时频图像对应的灰度图像,以Tsallis交叉熵最小化作为目标函数,求出灰度图像的最佳分割阈值,并根据分割阈值构建时频滤波器,实现干扰抑制。仿真结果表明:该方法对于SSC移频干扰产生的假目标具有较好的抑制效果,干扰抑制比可达30 dB以上。展开更多
The axon initial segment(AIS)region is crucial for action potential initiation due to the presence of high-density AIS protein voltage-gated sodium channels(Nav).Nav channels comprise several serine residues responsib...The axon initial segment(AIS)region is crucial for action potential initiation due to the presence of high-density AIS protein voltage-gated sodium channels(Nav).Nav channels comprise several serine residues responsible for the recruitment of Nav channels into the structure of AIS through interactions with ankyrin-G(AnkG).In this study,a series of computational experiments are performed to understand the role of AIS proteins casein kinase 2 and AnkG on Nav channel recruitment into the AIS.The computational simulation results using Virtual cell software indicate that Nav channels with all serine sites available for phosphorylation bind to AnkG with strong affinity.At the low initial concentration of AnkG and casein kinase 2,the concentration of Nav channels reduces significantly,suggesting the importance of casein kinase 2 and AnkG in the recruitment of Nav channels.展开更多
The liver has eight segments, which are referred to by numbers or by names. The numbering of the segments is done in a counterclockwise manner with the liver being viewed from the inferior surface, starting from Segme...The liver has eight segments, which are referred to by numbers or by names. The numbering of the segments is done in a counterclockwise manner with the liver being viewed from the inferior surface, starting from Segment Ⅰ(the caudate lobe). Standard anatomical description of the liver segments is available by computed tomographic scan and ultrasonography. Endoscopic ultrasound(EUS) has been used for a detailed imaging of many intra-abdominal organs and for the assessment of intra-abdominal vasculature. A stepwise evaluation of the liver segments by EUS has not been described. In this article, we have described a stepwise evaluation of the liver segments by EUS. This information can be useful for planning successful radical surgeries, preparing for biopsy, portal vein embolization, transjugular intrahepatic portosystemic shunt, tumour resection or partial hepatectomy, and for planning EUS guided diagnostic and therapeutic procedures.展开更多
In this paper, the optimization of quantizer’s segment threshold is done. The quantizer is designed on the basis of approximative spline functions. Coefficients on which we form approximative spline functions are cal...In this paper, the optimization of quantizer’s segment threshold is done. The quantizer is designed on the basis of approximative spline functions. Coefficients on which we form approximative spline functions are calculated by minimization mean square error (MSE). For coefficients determined in this way, spline functions by which optimal compressor function is approximated are obtained. For the quantizer designed on the basis of approximative spline functions, segment threshold is numerically determined depending on maximal value of the signal to quantization noise ratio (SQNR). Thus, quantizer with optimized segment threshold is achieved. It is shown that by quantizer model designed in this way and proposed in this paper, the SQNR that is very close to SQNR of nonlinear optimal companding quantizer is achieved.展开更多
文摘In this study,a novel hybrid Water Cycle Moth-Flame Optimization(WCMFO)algorithm is proposed for multilevel thresholding brain image segmentation in Magnetic Resonance(MR)image slices.WCMFO constitutes a hybrid between the two techniques,comprising the water cycle and moth-flame optimization algorithms.The optimal thresholds are obtained by maximizing the between class variance(Otsu’s function)of the image.To test the performance of threshold searching process,the proposed algorithm has been evaluated on standard benchmark of ten axial T2-weighted brain MR images for image segmentation.The experimental outcomes infer that it produces better optimal threshold values at a greater and quicker convergence rate.In contrast to other state-of-the-art methods,namely Adaptive Wind Driven Optimization(AWDO),Adaptive Bacterial Foraging(ABF)and Particle Swarm Optimization(PSO),the proposed algorithm has been found to be better at producing the best objective function,Peak Signal-to-Noise Ratio(PSNR),Standard Deviation(STD)and lower computational time values.Further,it was observed thatthe segmented image gives greater detail when the threshold level increases.Moreover,the statistical test result confirms that the best and mean values are almost zero and the average difference between best and mean value 1.86 is obtained through the 30 executions of the proposed algorithm.Thus,these images will lead to better segments of gray,white and cerebrospinal fluid that enable better clinical choices and diagnoses using a proposed algorithm.
文摘Segmentation has been an effective step that needs to be done before the classification or detection of an anomaly like Alzheimer’s on a brain scan.Segmentation helps detect pixels of the same intensity or volume and group them together as one class or region,where in that particular region of interest(ROI)can be concentrated on,rather than focusing on the entire image.In this paper White Matter Hyperintensities(WMH)is taken as a strong biomarker that supports and determines the presence of Alzheimer’s.As thefirst step a proper segmentation of the lesions has to be carried out.As pointed out in various other research papers,when the WMH area is very small or in places like the Septum Pellucidum the detection of the lesion is hard tofind.To overcome such problem areas a very optimized and accurate Threshold would be required to have a precise segmentation to detect the area of localization.This would help in proper detection and classification of the Anomaly.In this paper an elaborate comparison of various thresholding techniques has been done for segmentation.A novel idea for detection of Alzheimer’s has been presented in this paper,which encompasses the effectiveness of an optimized and adaptive technique.The Unet architecture has been taken as the baseline model with an adaptive kernel model embedded within the architecture.Various state-of-the-art technologies have been used with the dataset and a comparative study has been presented with the current architecture used in the paper.The lesion segmentation in narrow areas has accurately been detected compared to the other models and the number of false positives has been reduced to a great extent.
文摘根据频谱扩展-压缩(spectrum spread and compression,SSC)移频干扰信号和回波信号时频分布特性的差异,提出一种基于广义S变换和Tsallis交叉熵阈值分割的干扰抑制方法。分析了SSC移频干扰的干扰原理和干扰信号经过解线调后的信号形式,并利用时频聚焦性较好的广义S变换获取接收信号经过解线调后的时频图像,根据时频图像对应的灰度图像,以Tsallis交叉熵最小化作为目标函数,求出灰度图像的最佳分割阈值,并根据分割阈值构建时频滤波器,实现干扰抑制。仿真结果表明:该方法对于SSC移频干扰产生的假目标具有较好的抑制效果,干扰抑制比可达30 dB以上。
文摘The axon initial segment(AIS)region is crucial for action potential initiation due to the presence of high-density AIS protein voltage-gated sodium channels(Nav).Nav channels comprise several serine residues responsible for the recruitment of Nav channels into the structure of AIS through interactions with ankyrin-G(AnkG).In this study,a series of computational experiments are performed to understand the role of AIS proteins casein kinase 2 and AnkG on Nav channel recruitment into the AIS.The computational simulation results using Virtual cell software indicate that Nav channels with all serine sites available for phosphorylation bind to AnkG with strong affinity.At the low initial concentration of AnkG and casein kinase 2,the concentration of Nav channels reduces significantly,suggesting the importance of casein kinase 2 and AnkG in the recruitment of Nav channels.
文摘The liver has eight segments, which are referred to by numbers or by names. The numbering of the segments is done in a counterclockwise manner with the liver being viewed from the inferior surface, starting from Segment Ⅰ(the caudate lobe). Standard anatomical description of the liver segments is available by computed tomographic scan and ultrasonography. Endoscopic ultrasound(EUS) has been used for a detailed imaging of many intra-abdominal organs and for the assessment of intra-abdominal vasculature. A stepwise evaluation of the liver segments by EUS has not been described. In this article, we have described a stepwise evaluation of the liver segments by EUS. This information can be useful for planning successful radical surgeries, preparing for biopsy, portal vein embolization, transjugular intrahepatic portosystemic shunt, tumour resection or partial hepatectomy, and for planning EUS guided diagnostic and therapeutic procedures.
基金Serbian Ministry of Education and Science through Mathematical Institute of Serbian Academy of Sciences and Arts(Project III44006)Serbian Ministry of Education and Science(Project TR32035)
文摘In this paper, the optimization of quantizer’s segment threshold is done. The quantizer is designed on the basis of approximative spline functions. Coefficients on which we form approximative spline functions are calculated by minimization mean square error (MSE). For coefficients determined in this way, spline functions by which optimal compressor function is approximated are obtained. For the quantizer designed on the basis of approximative spline functions, segment threshold is numerically determined depending on maximal value of the signal to quantization noise ratio (SQNR). Thus, quantizer with optimized segment threshold is achieved. It is shown that by quantizer model designed in this way and proposed in this paper, the SQNR that is very close to SQNR of nonlinear optimal companding quantizer is achieved.