As the Yangtze River Estuary and adjacent sea have been classified as a problem area with regard to eutrophication, it is important to explore the spatial and temporal variations of nitrogen and phosphorus （N/P） nut...As the Yangtze River Estuary and adjacent sea have been classified as a problem area with regard to eutrophication, it is important to explore the spatial and temporal variations of nitrogen and phosphorus （N/P） nutrients in this area. Based on danish hydraulic institute （DHI）＇s open platform Ecolab, a hydrodynamic and water quality model was developed for the Yangtze River Estuary, in which the transport and transformation processes of different forms of N/P nutrients were considered. Validations against measured data show that the model is overall reliable. Preliminary application of the model suggests that the model can simulate the characteristics of high phosphorus concentration area in the Yangtze River Estuary, and the high concentration area is closely related to the resuspension process of particulate phosphorus.展开更多
According to the well-established light-to-electricity conversion theory,resonant excited carriers in the quantum dots will relax to the ground states and cannot escape from the quantum dots to form photocurrent,which...According to the well-established light-to-electricity conversion theory,resonant excited carriers in the quantum dots will relax to the ground states and cannot escape from the quantum dots to form photocurrent,which have been observed in quantum dots without a p–n junction at an external bias.Here,we experimentally observed more than 88% of the resonantly excited photo carriers escaping from In As quantum dots embedded in a short-circuited p–n junction to form photocurrent.The phenomenon cannot be explained by thermionic emission,tunneling process,and intermediate-band theories.A new mechanism is suggested that the photo carriers escape directly from the quantum dots to form photocurrent rather than relax to the ground state of quantum dots induced by a p–n junction.The finding is important for understanding the low-dimensional semiconductor physics and applications in solar cells and photodiode detectors.展开更多
According to the one-dimensional quantum state distribution, carrier scattering, and fixed range hopping model, the structural stability and electron transport properties of N-, P-, and As-doped SiC nanowires(N-SiCNWs...According to the one-dimensional quantum state distribution, carrier scattering, and fixed range hopping model, the structural stability and electron transport properties of N-, P-, and As-doped SiC nanowires(N-SiCNWs, P-SiCNWs, and As-SiCNWs) are simulated by using the first principles calculations. The results show that the lattice structure of NSiCNWs is the most stable in the lattice structures of the above three kinds of doped SiCNWs. At room temperature,for unpassivated SiCNWs, the doping effect of P and As are better than that of N. After passivation, the conductivities of all doped SiCNWs increase by approximately two orders of magnitude. The N-SiCNW has the lowest conductivity. In addition, the N-, P-, As-doped SiCNWs before and after passivation have the same conductivity–temperature characteristics,that is, above room temperature, the conductivity values of the doped SiCNWs all increase with temperature increasing.These results contribute to the electronic application of nanodevices.展开更多
Absolute geostrophic currents in the North Pacific Ocean are calculated using the P-vector method and gridded Argo profiling data from January 2004 to December 2012. Three-dimensional structures and seasonal variabili...Absolute geostrophic currents in the North Pacific Ocean are calculated using the P-vector method and gridded Argo profiling data from January 2004 to December 2012. Three-dimensional structures and seasonal variability of meridional heat transport(MHT) and meridional salt transport(MST) are analyzed. The results show that geostrophic and Ekman components are generally opposite in sign, with the southward geostrophic component dominating in the subtropics and the northward Ekman component dominating in the tropics. In combination with the net surface heat flux and the MST through the Bering Strait, the MHT and MST of the western boundary currents(WBCs) are estimated for the fi rst time. The results suggest that the WBCs are of great importance in maintaining the heat and salt balance of the North Pacifi c. The total interior MHT and MST in the tropics show nearly the same seasonal variability as that of the Ekman components, consistent with the variability of zonal wind stress. The geostrophic MHT in the tropics is mainly concentrated in the upper layers, while MST with large amplitude and annual variation can extend much deeper. This suggests that shallow processes dominate MHT in the North Pacific, while MST can be affected by deep ocean circulation. In the extratropical ocean, both MHT and MST are weak. However, there is relatively large and irregular seasonal variability of geostrophic MST, suggesting the importance of the geostrophic circulation in the MST of that area.展开更多
We focus on two new 21） materials, i.e., monolayer and bilayer silicon phosphides （Sil P1）. Based on the elastic- scattering Green＇s function, the electronic-transport properties of two-dimensional monolayer and b...We focus on two new 21） materials, i.e., monolayer and bilayer silicon phosphides （Sil P1）. Based on the elastic- scattering Green＇s function, the electronic-transport properties of two-dimensional monolayer and bilayer Au- Si1P1-Au molecular junctions are studied. It is found that their bandgaps are narrow （0.16eV for a monolayer molecular junction and 0.26 e V for a bilayer molecular junction）. Moreover, the calculated current-voltage char- acteristics indicate that the monolayer molecular junction provides constant output current （20 hA） over a wide voltage range, and the bilayer molecular junction provides higher current （42 hA）.展开更多
The World Health Organisation recommends exclusive breastfeeding for the first six months of an infant's life and in combination with solid food thereafter. This recommendation was introduced based on research sho...The World Health Organisation recommends exclusive breastfeeding for the first six months of an infant's life and in combination with solid food thereafter. This recommendation was introduced based on research showing numerous health benefits of breastfeeding for both the mother and the infant. However, there is always concern regarding the transfer of medications from mother to their breastfed baby via milk. Pharmacokinetic properties of a drug are usually used to predict its transferability into breast milk. Although most drugs are compatible with breastfeeding, cases of toxic drug exposure have been reported. This is thought to be due to active transport mechanisms whereby efflux transporter proteins expressed in the epithelial cells of the mammary gland actively secrete drugs into milk. An example of such efflux transporters including the breast cancer resistance protein which is strongly induced during lactation and this could result in contamination of milk with the substrates of this transporter which may place the suckling infant at risk of toxicity. Furthermore, there is little known about the substrate specificity of most efflux transporters as we have highlighted in this review. There also exists some degree of contradiction between in vivo and in vitro studies which makes it difficult to conclusively predict outcomes and drug-drug interactions.展开更多
Since rail-road transport uses road and rail networks and requires the transshipment infrastructures at the terminals, its competitiveness depends not only on the costs but also on the location of these terminals. Thi...Since rail-road transport uses road and rail networks and requires the transshipment infrastructures at the terminals, its competitiveness depends not only on the costs but also on the location of these terminals. This paper focused on providing a methodology for determining the optimal locations for intermodal freight transportation terminals in consolidation network. The goal is to minimize total costs in order to increase the efficiency of the transportation system. This paper also has allowed us to have an overview of the methods and models that exist for solving the problem of intermodal and terminal locating.展开更多
In recent Japan, as there has been an increase of dual-income households and the demand for childcare facilities has especially increased especially in urban areas, childcare facilities and workers are lacking and it ...In recent Japan, as there has been an increase of dual-income households and the demand for childcare facilities has especially increased especially in urban areas, childcare facilities and workers are lacking and it leads to the serious issue of children on waiting lists. Based on the background mentioned above, using statistical method, geographical information system (GIS) and public open data, scenario analysis to select transportation, the present study aimed to propose a method to quantitatively evaluate the current location of childcare facilities in Japanese urban areas. In the present study, the model of the p-median problem used to obtain the optimal location of facilities was modified, and a method to evaluate the current situation concerning the shortage or overage of childcare facilities by district was proposed. As evaluations are conducted using quantitative data such as the specialization coefficient of person trip for transportation and the distance between childcare facilities and districts, the evaluation results are also quantitative, making it an effective indicator for evaluating the locations of childcare facilities. Additionally, the specialization coefficient of person trip for transportation and the distance between childcare facilities and districts were calculated based on public open data. Therefore, the evaluation method in the present study has a high temporal reproducibility as well as spatial reproducibility.展开更多
We investigate the electronic-transport properties of two-dimensional monolayer films from Au-P-Au molecular junction to Au-Si-Au molecular junction using elastic scattering Green＇s function theory. In the process of...We investigate the electronic-transport properties of two-dimensional monolayer films from Au-P-Au molecular junction to Au-Si-Au molecular junction using elastic scattering Green＇s function theory. In the process of replacing the P atoms with Si atoms every other line from the middle of monolayer blue phosphorus molecular structure, the substitution of Si atoms changes the properties of Au-P-Au molecular junction significantly. Interestingly, the current value has a symmetric change as a parabolic curve with the peak appearing in Au-Si_1P_1-Au molecular junction, which provides the most stable current of 15.00 nA in a wide voltage range of 0.70-2.70 V.Moreover, the current-voltage characteristics of the structures indicate that the steps tend to disappear revealing the property similar to metal when the Si atoms dominate the molecular junction.展开更多
基金Project supported by the National Natural Science Foun-dation of China(Grant Nos.10972134,11032007)the Scienti-fic research project of Shanghai Municipal Oceanic Bureau(Grant Nos.2011-06,2014-01)the Shanghai Scientific Research Project(Grant Nos.13231203600,14231200104)
文摘As the Yangtze River Estuary and adjacent sea have been classified as a problem area with regard to eutrophication, it is important to explore the spatial and temporal variations of nitrogen and phosphorus （N/P） nutrients in this area. Based on danish hydraulic institute （DHI）＇s open platform Ecolab, a hydrodynamic and water quality model was developed for the Yangtze River Estuary, in which the transport and transformation processes of different forms of N/P nutrients were considered. Validations against measured data show that the model is overall reliable. Preliminary application of the model suggests that the model can simulate the characteristics of high phosphorus concentration area in the Yangtze River Estuary, and the high concentration area is closely related to the resuspension process of particulate phosphorus.
基金We thank Yingfang Liu （Institute of Biophysics, Chinese Acad- emy of Sciences） for advice on PX domain structure and SNX6 mutations. We are particularly grateful to Yanmin Yang （Stanford University, USA） for insightful discussions and the Flag-MAP1B LC construct. We also thank Juan S Bonifacino （NIH, USA） for the rabbit anti-CI-MPR antibody, Hiroyoshi Ariga （Hokkaido University, Japan） for Flag- and HA-tagged human SNX6 overexpression constructs, and Li Yu （Tsinghua University, China） for the YFP-EEA1 expression construct. We thank Chonglin Yang （Institute of Genetics and Developmental Biology, Chinese Academy of Sciences）, Dahua Chen （Institute of Zoology, Chinese Academy of Sciences） and Li Yu for critical reading of the manuscript. This work was supported by grants from the National Natural Science Foundation of China （30770675） and Chinese Academy of Sciences （KSCX1-YW-R-37）. J-J Liu is supported by the CAS 100-Tal- ents Program.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11574362,61210014,11374340,and 11474205)the Innovative Clean-Energy Research and Application Program of Beijing Municipal Science and Technology Commission,China(Grant No.Z151100003515001)
文摘According to the well-established light-to-electricity conversion theory,resonant excited carriers in the quantum dots will relax to the ground states and cannot escape from the quantum dots to form photocurrent,which have been observed in quantum dots without a p–n junction at an external bias.Here,we experimentally observed more than 88% of the resonantly excited photo carriers escaping from In As quantum dots embedded in a short-circuited p–n junction to form photocurrent.The phenomenon cannot be explained by thermionic emission,tunneling process,and intermediate-band theories.A new mechanism is suggested that the photo carriers escape directly from the quantum dots to form photocurrent rather than relax to the ground state of quantum dots induced by a p–n junction.The finding is important for understanding the low-dimensional semiconductor physics and applications in solar cells and photodiode detectors.
基金Project supported by the National Natural Science Foundation of China(Grant No.11574261)the Natural Science Foundation of Hebei Province,China(Grant No.A2015203261)。
文摘According to the one-dimensional quantum state distribution, carrier scattering, and fixed range hopping model, the structural stability and electron transport properties of N-, P-, and As-doped SiC nanowires(N-SiCNWs, P-SiCNWs, and As-SiCNWs) are simulated by using the first principles calculations. The results show that the lattice structure of NSiCNWs is the most stable in the lattice structures of the above three kinds of doped SiCNWs. At room temperature,for unpassivated SiCNWs, the doping effect of P and As are better than that of N. After passivation, the conductivities of all doped SiCNWs increase by approximately two orders of magnitude. The N-SiCNW has the lowest conductivity. In addition, the N-, P-, As-doped SiCNWs before and after passivation have the same conductivity–temperature characteristics,that is, above room temperature, the conductivity values of the doped SiCNWs all increase with temperature increasing.These results contribute to the electronic application of nanodevices.
基金Supported by the National Basic Research Program of China(973 Program)(No.2012CB956001)the CMA(No.GYHY201306018)+2 种基金the Chinese Academy of Sciences(CAS)(No.XDA11010301)the National Natural Science Foundation of China(Nos.41176019,41421005,U1406401)the State Oceanic Administration(SOA)(No.GASI-03-01-01-05)
文摘Absolute geostrophic currents in the North Pacific Ocean are calculated using the P-vector method and gridded Argo profiling data from January 2004 to December 2012. Three-dimensional structures and seasonal variability of meridional heat transport(MHT) and meridional salt transport(MST) are analyzed. The results show that geostrophic and Ekman components are generally opposite in sign, with the southward geostrophic component dominating in the subtropics and the northward Ekman component dominating in the tropics. In combination with the net surface heat flux and the MST through the Bering Strait, the MHT and MST of the western boundary currents(WBCs) are estimated for the fi rst time. The results suggest that the WBCs are of great importance in maintaining the heat and salt balance of the North Pacifi c. The total interior MHT and MST in the tropics show nearly the same seasonal variability as that of the Ekman components, consistent with the variability of zonal wind stress. The geostrophic MHT in the tropics is mainly concentrated in the upper layers, while MST with large amplitude and annual variation can extend much deeper. This suggests that shallow processes dominate MHT in the North Pacific, while MST can be affected by deep ocean circulation. In the extratropical ocean, both MHT and MST are weak. However, there is relatively large and irregular seasonal variability of geostrophic MST, suggesting the importance of the geostrophic circulation in the MST of that area.
基金Supported by the National Natural Science Foundation of China under Grant No 11374033
文摘We focus on two new 21） materials, i.e., monolayer and bilayer silicon phosphides （Sil P1）. Based on the elastic- scattering Green＇s function, the electronic-transport properties of two-dimensional monolayer and bilayer Au- Si1P1-Au molecular junctions are studied. It is found that their bandgaps are narrow （0.16eV for a monolayer molecular junction and 0.26 e V for a bilayer molecular junction）. Moreover, the calculated current-voltage char- acteristics indicate that the monolayer molecular junction provides constant output current （20 hA） over a wide voltage range, and the bilayer molecular junction provides higher current （42 hA）.
文摘The World Health Organisation recommends exclusive breastfeeding for the first six months of an infant's life and in combination with solid food thereafter. This recommendation was introduced based on research showing numerous health benefits of breastfeeding for both the mother and the infant. However, there is always concern regarding the transfer of medications from mother to their breastfed baby via milk. Pharmacokinetic properties of a drug are usually used to predict its transferability into breast milk. Although most drugs are compatible with breastfeeding, cases of toxic drug exposure have been reported. This is thought to be due to active transport mechanisms whereby efflux transporter proteins expressed in the epithelial cells of the mammary gland actively secrete drugs into milk. An example of such efflux transporters including the breast cancer resistance protein which is strongly induced during lactation and this could result in contamination of milk with the substrates of this transporter which may place the suckling infant at risk of toxicity. Furthermore, there is little known about the substrate specificity of most efflux transporters as we have highlighted in this review. There also exists some degree of contradiction between in vivo and in vitro studies which makes it difficult to conclusively predict outcomes and drug-drug interactions.
文摘Since rail-road transport uses road and rail networks and requires the transshipment infrastructures at the terminals, its competitiveness depends not only on the costs but also on the location of these terminals. This paper focused on providing a methodology for determining the optimal locations for intermodal freight transportation terminals in consolidation network. The goal is to minimize total costs in order to increase the efficiency of the transportation system. This paper also has allowed us to have an overview of the methods and models that exist for solving the problem of intermodal and terminal locating.
文摘In recent Japan, as there has been an increase of dual-income households and the demand for childcare facilities has especially increased especially in urban areas, childcare facilities and workers are lacking and it leads to the serious issue of children on waiting lists. Based on the background mentioned above, using statistical method, geographical information system (GIS) and public open data, scenario analysis to select transportation, the present study aimed to propose a method to quantitatively evaluate the current location of childcare facilities in Japanese urban areas. In the present study, the model of the p-median problem used to obtain the optimal location of facilities was modified, and a method to evaluate the current situation concerning the shortage or overage of childcare facilities by district was proposed. As evaluations are conducted using quantitative data such as the specialization coefficient of person trip for transportation and the distance between childcare facilities and districts, the evaluation results are also quantitative, making it an effective indicator for evaluating the locations of childcare facilities. Additionally, the specialization coefficient of person trip for transportation and the distance between childcare facilities and districts were calculated based on public open data. Therefore, the evaluation method in the present study has a high temporal reproducibility as well as spatial reproducibility.
基金Supported by the National Natural Science Foundation of China under Grant Nos 11374033,11774030,51735001 and 61775016the Fundamental Research Funds for the Central Universities under Grant No 2017CX10007
文摘We investigate the electronic-transport properties of two-dimensional monolayer films from Au-P-Au molecular junction to Au-Si-Au molecular junction using elastic scattering Green＇s function theory. In the process of replacing the P atoms with Si atoms every other line from the middle of monolayer blue phosphorus molecular structure, the substitution of Si atoms changes the properties of Au-P-Au molecular junction significantly. Interestingly, the current value has a symmetric change as a parabolic curve with the peak appearing in Au-Si_1P_1-Au molecular junction, which provides the most stable current of 15.00 nA in a wide voltage range of 0.70-2.70 V.Moreover, the current-voltage characteristics of the structures indicate that the steps tend to disappear revealing the property similar to metal when the Si atoms dominate the molecular junction.
