Objective To the investigate the mechanism of capsaicin in psoriasis vulgaris. Methods Substance P(SP) in psoriatic lesions before and 6 weeks after the treatment with capsaicin was detedted by radioimmunoassary. Re...Objective To the investigate the mechanism of capsaicin in psoriasis vulgaris. Methods Substance P(SP) in psoriatic lesions before and 6 weeks after the treatment with capsaicin was detedted by radioimmunoassary. Results After 3 weeks and 6 weeks treatment with capsaicin, SP in psoriatic lesions was decreased ( P <0.05), while it in the self control group was not decreased; Overall the efficient incidence in therapeutic group was 78.8% , while it in the control group was 36.8% . There was significant difference between them (χ 2 =16.30, P<0.001). Conclusion Capsaicin inhibits dermal inflammatory responses and proliferation of keratinocytes by decreasing the expression of SP in psoriasis vulgaris.展开更多
The development of a reliable green chemistry process for the biogenic synthesis of nanomaterials is an important aspect of current nanotechnology research. Silver nanoparticles (AgNPs) have been used as antimicrobial...The development of a reliable green chemistry process for the biogenic synthesis of nanomaterials is an important aspect of current nanotechnology research. Silver nanoparticles (AgNPs) have been used as antimicrobial and disinfectant agents. However, there is limited information about its toxicity. Therefore, this study focused on the biosynthesis of AgNPs by the bacterium Proteus mirabilis and on determining its preliminary toxic effect on some aspects of animal physiology. A green method for the synthesis of AgNPs using culture supernatant of Proteus mirabilis has been developed in this study and the synthesized AgNPs were characterized by several techniques. The AgNPs showed a maximum absorbance at 445 nm on ultraviolet-visible spectra. The presence of proteins was identified by Fourier transform-infrared spectroscopy. The reduction of Ag+ to elemental silver was characterized by X-ray spectroscopy analysis. The transmission electron micrograph revealed the formation of polydispersed nanoparticles of 5 - 45 nm. The AgNPs were evaluated for their toxic effect on pregnant female albino rat. The result showed that liver enzymes (AST and ALP) were decreased significantly in the group treated with AgNPs. Mean corpuscular hemoglobin concentration also showed significant increase.展开更多
Production of common bean (Phaseolus vulgaris) is often limited by the low availability of soil phosphorus (P). Identification of common bean genotypes adapted to low phosphorus (P) availability may be a feasible stra...Production of common bean (Phaseolus vulgaris) is often limited by the low availability of soil phosphorus (P). Identification of common bean genotypes adapted to low phosphorus (P) availability may be a feasible strategy to overcome the poor plant growth and production in P-deficient soils. Genetic variation for P response of thirteen common bean genotypes was studied under screen house controlled conditions using triple super phosphate as P source. The common bean genotypes varied in leaf area, shoot mass, root mass, total root length, basal and lateral roots production, shoot P concentration and P uptake under phosphorous deficiency and high phosphorous. All the measured variables were significantly correlated with each other, which in turn were correlated to P uptake. Generally the large-seeded genotypes RWR 1946 and RWR 2075 appeared to have the best growth, hence superior P efficiency under low P availability, while at the same time they were more responsive to added P. These results complement the earlier field based observed tolerance to low soil phosphorous of the selected genotypes under the BILFA strategy.展开更多
文摘Objective To the investigate the mechanism of capsaicin in psoriasis vulgaris. Methods Substance P(SP) in psoriatic lesions before and 6 weeks after the treatment with capsaicin was detedted by radioimmunoassary. Results After 3 weeks and 6 weeks treatment with capsaicin, SP in psoriatic lesions was decreased ( P <0.05), while it in the self control group was not decreased; Overall the efficient incidence in therapeutic group was 78.8% , while it in the control group was 36.8% . There was significant difference between them (χ 2 =16.30, P<0.001). Conclusion Capsaicin inhibits dermal inflammatory responses and proliferation of keratinocytes by decreasing the expression of SP in psoriasis vulgaris.
文摘The development of a reliable green chemistry process for the biogenic synthesis of nanomaterials is an important aspect of current nanotechnology research. Silver nanoparticles (AgNPs) have been used as antimicrobial and disinfectant agents. However, there is limited information about its toxicity. Therefore, this study focused on the biosynthesis of AgNPs by the bacterium Proteus mirabilis and on determining its preliminary toxic effect on some aspects of animal physiology. A green method for the synthesis of AgNPs using culture supernatant of Proteus mirabilis has been developed in this study and the synthesized AgNPs were characterized by several techniques. The AgNPs showed a maximum absorbance at 445 nm on ultraviolet-visible spectra. The presence of proteins was identified by Fourier transform-infrared spectroscopy. The reduction of Ag+ to elemental silver was characterized by X-ray spectroscopy analysis. The transmission electron micrograph revealed the formation of polydispersed nanoparticles of 5 - 45 nm. The AgNPs were evaluated for their toxic effect on pregnant female albino rat. The result showed that liver enzymes (AST and ALP) were decreased significantly in the group treated with AgNPs. Mean corpuscular hemoglobin concentration also showed significant increase.
文摘Production of common bean (Phaseolus vulgaris) is often limited by the low availability of soil phosphorus (P). Identification of common bean genotypes adapted to low phosphorus (P) availability may be a feasible strategy to overcome the poor plant growth and production in P-deficient soils. Genetic variation for P response of thirteen common bean genotypes was studied under screen house controlled conditions using triple super phosphate as P source. The common bean genotypes varied in leaf area, shoot mass, root mass, total root length, basal and lateral roots production, shoot P concentration and P uptake under phosphorous deficiency and high phosphorous. All the measured variables were significantly correlated with each other, which in turn were correlated to P uptake. Generally the large-seeded genotypes RWR 1946 and RWR 2075 appeared to have the best growth, hence superior P efficiency under low P availability, while at the same time they were more responsive to added P. These results complement the earlier field based observed tolerance to low soil phosphorous of the selected genotypes under the BILFA strategy.
