医学影像存档与通讯系统(PACS)是医疗工作数字化的支撑,此系统遵循DICOM3.0标准,本文研究的PACS系统是在综合调研了医院相关科室的工作流程后,结合国内小型医院的实际需求,采用C/S模式进行开发的一个数字化医院的适用的软件,完成了医院...医学影像存档与通讯系统(PACS)是医疗工作数字化的支撑,此系统遵循DICOM3.0标准,本文研究的PACS系统是在综合调研了医院相关科室的工作流程后,结合国内小型医院的实际需求,采用C/S模式进行开发的一个数字化医院的适用的软件,完成了医院中影像数据的存储、传递和显示。本软件使用Visualstudio2008作为本系统的开发工具,采用SQL Sever 2005作为后台数据库环境。展开更多
A novel class of molecules with structure N-（3-arylpropyl）-9,10-dihydro-9-oxoacridine-4-carboxamides （20- 29） were designed by generating a pharmacophore for potent MDR reversal activity using phase drug design so...A novel class of molecules with structure N-（3-arylpropyl）-9,10-dihydro-9-oxoacridine-4-carboxamides （20- 29） were designed by generating a pharmacophore for potent MDR reversal activity using phase drug design software. The designed molecules were synthesized by a novel synthesis route and evaluated for their inhibitory effects on the transport activity of P-glycoprotein （P-gp） by standard Hoechst 33342 assay method. Based on the pIC50 values of ten title compounds screened, three compounds exhibited better activity as compared to Verapamil used as standard.展开更多
文摘医学影像存档与通讯系统(PACS)是医疗工作数字化的支撑,此系统遵循DICOM3.0标准,本文研究的PACS系统是在综合调研了医院相关科室的工作流程后,结合国内小型医院的实际需求,采用C/S模式进行开发的一个数字化医院的适用的软件,完成了医院中影像数据的存储、传递和显示。本软件使用Visualstudio2008作为本系统的开发工具,采用SQL Sever 2005作为后台数据库环境。
文摘A novel class of molecules with structure N-（3-arylpropyl）-9,10-dihydro-9-oxoacridine-4-carboxamides （20- 29） were designed by generating a pharmacophore for potent MDR reversal activity using phase drug design software. The designed molecules were synthesized by a novel synthesis route and evaluated for their inhibitory effects on the transport activity of P-glycoprotein （P-gp） by standard Hoechst 33342 assay method. Based on the pIC50 values of ten title compounds screened, three compounds exhibited better activity as compared to Verapamil used as standard.
