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Low-grade myofibrosarcoma of the maxillary sinus:Two case reports
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作者 Anna Mydlak ŁukaszŚcibik +4 位作者 Monika Durzynska Jakub Zwoliński Karolina Buchajska Olga Lenartowicz Jakub Kucharz 《World Journal of Clinical Oncology》 2024年第4期566-575,共10页
BACKGROUND Low-grade myofibroblastic sarcoma(LGMS)is an extremely rare tumor characterized by the malignant proliferation of myofibroblasts.LGMS most commonly develops in adults,predominantly in males,in the head and ... BACKGROUND Low-grade myofibroblastic sarcoma(LGMS)is an extremely rare tumor characterized by the malignant proliferation of myofibroblasts.LGMS most commonly develops in adults,predominantly in males,in the head and neck region,oral cavity,especially on the tongue,mandible,and larynx.This article presents 2 cases of LGMS localized to the maxillary sinus and provides an overview of the available literature.CASE SUMMARY Two patients with LGMS located in the maxillary sinus underwent surgery at the Department of Head and Neck Surgery.Case 1:A 46-year-old patient was admitted to the clinic with suspected LGMS recurrence in the right maxillary sinus(rT4aN0M0),with symptoms of pain in the suborbital area,watering of the right eye,thick discharge from the right nostril,and augmented facial asymmetry.After open biopsy-confirmed LGMS,the patient underwent expanded maxillectomy of the right side with immediate palate reconstruction using a microvascular skin flap harvested surgically from the middle arm.The patient qualified for adjuvant radiotherapy for the postoperative bed,with an additional margin.Currently,the patient is under 1.5 years of observation with no evidence of disease.Case 2:A 45-year-old man was admitted to our clinic with facial asymmetry,strabismus,exophthalmos,and visual impairment in the right eye.Six months earlier,the patient had undergone partial jaw resection at another hospital for fibromatosis.A contrast-enhanced computed tomography scan revealed a tumor mass in the postoperative log after an earlier procedure.An open biopsy confirmed lowgrade fibrosarcoma(rT4aN0M0).The patient qualified for an extended total right maxillectomy with orbital excision and right hemimandibulectomy with immediate microvascular reconstruction using an anterolateral thigh flap.The patient subsequently underwent adjuvant radiotherapy to the postoperative area.After 9 months,recurrence occurred in the right mandibular arch below the irradiated area.The lesion infiltrated the base of the skull,which warranted the withdrawal of radiotherapy and salvage surgery.The patient qualified for palliative chemotherapy with a regimen of doxorubicin+dacarbazine+cyclophosphamide and palliative radiotherapy for bone metastases.The patient died 26 months after surgical treatment.The cases have been assessed and compared with cases in the literature.CONCLUSION No specific diagnostic criteria or treatment strategies have been developed for LGMS.The treatment used for LGMS is the same as that used for sinonasal cancer radical tumor excision;adjuvant radiotherapy or chemoradiotherapy should also be considered.They have low malignant potential but are highly invasive,tend to recur,and metastasize to distant sites.Patients should undergo regular follow-up examinations to detect recurrence or metastasis at an early stage.Patients should be treated and observed at the highest referral centers. 展开更多
关键词 Head and neck cancer paranasal sinuses Maxillary sinus SARCOMA Low-grade myofibroblastic sarcoma Case report
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Poor Reproducibility in the Evaluation of Paranasal Sinus X-Rays in Chronic Rhinosinusitis
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作者 A. Luukkainen E. Terna +9 位作者 J. Numminen A. Markkola P. Dastidar J. Jarnstedt H. Huhtala M. Karjalainen K. Blomgren P. Kauppi M. Rautiainen S. Toppila-Salmi 《Open Journal of Radiology》 2017年第1期23-34,共12页
Objective: The aim of this study was to evaluate intra- and inter-observer reproducibility of sinus x-rays in comparison to sinus computed tomography (CT) in chronic rhinosinusitis (CRS) patients. Methods: This was a ... Objective: The aim of this study was to evaluate intra- and inter-observer reproducibility of sinus x-rays in comparison to sinus computed tomography (CT) in chronic rhinosinusitis (CRS) patients. Methods: This was a prospective controlled study for which 14 adult CRS patients were recruited. Patients underwent a sinus multi-detector CT scan as well as additional sinus x-rays at the same time. Symptom interview and skin prick tests were performed. Lund-Mackay (LM) scores and 43 other findings in paranasal sinuses were analyzed by three blinded observers from CT-scans and x-rays. We compared agreement between sinus CT and x-rays (intra-observer reproducibility) and between three observers (inter-observer reproducibility) by Cohen’s kappa. Results: In at least 90% of the cases, the status of 47/49 structures was detectable in CT scans, whereas the status of only 8/49 structures was detectable in x-rays. The majority of the 25 visualized structures had poor intra-observer and inter-observer reproducibility. Conclusion: Only a few structures can be visualized in paranasal sinus x-rays and compared to paranasal sinus CT-scans, their reproducibility is poor. Our results strongly support the current consensus of radiation dose reduction by limiting the number of x-rays. 展开更多
关键词 sinusITIS paranasal sinus Computed Tomography Magnetic Resonance Imaging X-RAY
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Lung adenocarcinoma metastasis to paranasal sinus:A case report
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作者 Wen-Jing Li Hai-Xiang Xue +1 位作者 Jian-Qiang You Chang-Jiang Chao 《World Journal of Clinical Cases》 SCIE 2022年第17期5869-5876,共8页
BACKGROUND Lung cancer is often metastasized to the brain,liver,kidneys,bone,bone marrow,and adrenal glands;however,metastasis of primary lung cancer to the paranasal sinuses is extremely rare.CASE SUMMARY In this pap... BACKGROUND Lung cancer is often metastasized to the brain,liver,kidneys,bone,bone marrow,and adrenal glands;however,metastasis of primary lung cancer to the paranasal sinuses is extremely rare.CASE SUMMARY In this paper,we present a case of metastatic tumors of the sinus secondary to lung adenocarcinoma.The patient was a 46-year-old woman who underwent surgical removal of lung carcinoma.Four months after the surgical removal of the lung tumor,the patient presented with epistaxis,and on investigation,the diagnosis was confirmed to be nasal sinus tumors due to metastasis of lung adenocarcinoma.CONCLUSION Thorough investigation of patients with epistaxis and a history of lung cancer is necessary to diagnose metastatic sinus tumors.We reviewed relevant literature and found that there are no characteristic clinical or radiologic features for metastatic sinus tumors;however,the diagnosis can be confirmed by histopathological examination of biopsied tumor sample. 展开更多
关键词 Lung adenocarcinoma paranasal sinus METASTASIS Case report
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The Endonasal Endoscopic Management of Paranasal Sinuses Mucoceles
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作者 Sarah A. AlMansour Ali A. AlMomen 《International Journal of Otolaryngology and Head & Neck Surgery》 2021年第1期20-29,共10页
<strong>Introduction:</strong> Paranasal sinuses mucoceles are benign, epithelial lined, mucus filled lesions, causing destruction of the adjacent sinus walls, and with further gradual extension to adjacen... <strong>Introduction:</strong> Paranasal sinuses mucoceles are benign, epithelial lined, mucus filled lesions, causing destruction of the adjacent sinus walls, and with further gradual extension to adjacent structures, serious morbidities and mortalities may occur. <strong>Objective:</strong> To emphasize on the efficacy of endonasal endoscopic marsupialization in the treatment of paranasal sinus mucoceles. <strong>Method:</strong> Retrospective descriptive study on paranasal sinus mucocele cases operated on endoscopically by the author (AAM), in the 10-year-period from to 2009-2019. <strong>Result:</strong> Total of 23 cases were included, 16 were males and 7 females, age ranging between 14 - 76 years, with a mean age of 45 years Location of mucoceles varied between: Frontal 7 cases (30%), Fronto-ethmoidal 6 cases (26%), Isolated Ethmoidal accounted for 3 cases (13%), sphenoidal 4 cases (17%), maxillary were 3 cases (13%) all of the 23 cases underwent endonasal endoscopic complete marsupialization, none of them required combination with external approach in-spite of different locations and complications, with no recurrence in a mean follow up period of 2.4 years. <strong>Conclusion:</strong> Endonasal endoscopic approach is a safe, efficient approach in the treatment of most paranasal sinus mucocele case in their different presentations and locations. 展开更多
关键词 MUCOCELE paranasal sinus Chronic Rhinosinusitis Endoscopic sinus Surgery MARSUPIALIZATION
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Reproducibility of 3 mm-Slice-Thick Reconstruction of Paranasal Sinus Computed Tomography Scans
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作者 Matti Karjalainen Anna Julkunen +7 位作者 Antti Markkola Prasun Dastidar Heini Huhtala Mikko Suvinen Anna-Maija Kuukka Markus Rautiainen Jura Numminen Sanna Toppila-Salmi 《Open Journal of Radiology》 2016年第1期39-48,共10页
Background: After the failure of medical treatment, the surgery of chronic rhinosinusitis (CRS) is planned according to endoscopic and paranasal sinus computed tomography (CT) findings. Objective: The aim of this pros... Background: After the failure of medical treatment, the surgery of chronic rhinosinusitis (CRS) is planned according to endoscopic and paranasal sinus computed tomography (CT) findings. Objective: The aim of this prospective study was to evaluate whether this study method might be eligible in studies aiming at radiation dose reduction. Sinus CT scans were chosen as a model because of the high variation of the radiological anatomy of surgically important sinonasal structures. We hypothesized that 3 mm-slice-thick reconstruction CT had poor reproducibility. Methods: 59 CRS patients underwent routine multi-detector sinus CT (CT<sub>MD</sub>). CT<sub>3mm</sub> was reconstructed from CT<sub>MD</sub> data-sets. Lund-Mackay (LM) scores and 43 other structural parameters were analyzed blinded. Agreement was studied between CT<sub>MD</sub> and CT<sub>3mm</sub> (intra-observer reproducibility), and between three observers (inter-observer reproducibility) by using Cohen’s kappa. Results: The inter-observer agreement was moderate (kappa 0.4 - 0.6, p < 0.01) in the majority of structures of CT<sub>3mm</sub> scans. The intra-observer reproducibility of CT<sub>3mm</sub> scans was very good in most structures, however, it was poor in important structures such as frontal and spheno-ethmoid recess, lamina papyracae, and location of optic nerve or anterior ethmoidal artery. The grade of surgeon’s confidence of CT<sub>3mm</sub> in comparison to CT<sub>MD</sub> was lower (kappa 0.2 - 0.4, P < 0.05). Conclusion: This methodology might have some use in studies aiming at radiation dose reduction. As was expected, 3 mm-slice-thick reconstruction CT had poor reproducibility and surgeon’s confidence. More recent methods such as cone beam computed tomography scans have nowadays more relevant dose reduction potential. 展开更多
关键词 Chronic Rhinosinusitis Computed Tomography Image Reconstruction Inter-Observer Agreement Intra-Observer Agreement KAPPA Radiation-Dose Reduction REPRODUCIBILITY paranasal sinus sinus Imaging
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Sinonasal teratocarcinosarcoma involving the nasal cavity,unilateral paranasal sinuses,and intracranial invasion:A case report
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作者 Li-Yuan Fu Mi-Yang Yang +4 位作者 Pei-Yun Ye Zhao-Chu Wang Chu-Jie Chen Hui Li Shang-Wen Xu 《World Journal of Clinical Cases》 SCIE 2024年第25期5784-5790,共7页
BACKGROUND Sinonasal teratocarcinosarcoma(SNTCS)is a rare and highly invasive neoplasm originating from the nasal cavity and sinuses.Typically,it exhibits an invasive behavior towards adjacent structures;however,in ex... BACKGROUND Sinonasal teratocarcinosarcoma(SNTCS)is a rare and highly invasive neoplasm originating from the nasal cavity and sinuses.Typically,it exhibits an invasive behavior towards adjacent structures;however,in exceptional instances,it may infiltrate the intracranial compartment.Due to the tumor's rarity and lack of distinctive features on computed tomography(CT)and magnetic resonance imaging(MRI)images,SNTCS is often misdiagnosed.CASE SUMMARY In this study,we present a case of SNTCS in a 56-year-old patient who exhibited unexplained cognitive impairment before admission.CT and MRI scans revealed the presence of a mass in the right nasal cavity,with lesions extending to the right ethmoid sinus and right frontal region.Subsequently,the patient underwent pathological examination for confirmation and received surgical intervention to excise the tumor.The future advancement in our understanding of this disease will significantly contribute to the precise diagnosis and treatment of SNTCS.CONCLUSION SNTCS is an exceptionally rare malignant tumor that originates from the nasal cavity and paranasal sinuses,presenting a diagnostic challenge due to its nonspecific imaging findings.MRI accurately delineates the location,morphological characteristics,size,internal structure,extent of surrounding involvement,and metabolic information of the lesion.These aspects play a pivotal role in the precise localization and qualitative assessment of SNTCS.Nevertheless,a definitive diagnosis still requires a pathological biopsy. 展开更多
关键词 paranasal sinus Malignant tumor Sinonasal teratocarcinosarcoma Brain invasion Case report
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Epstein-Barr virus-positive diffuse large B-cell lymphoma with human immunodeficiency virus mimicking complicated frontal sinusitis:A case report
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作者 Seokho Yoon Kyeong Hwa Ryu +2 位作者 Hye Jin Baek Hyo Jung An Yeon-Hee Joo 《World Journal of Clinical Cases》 SCIE 2021年第7期1654-1660,共7页
BACKGROUND Primary non-Hodgkin’s lymphoma of the frontal sinus is extremely rare.In addition,Epstein-Barr virus(EBV)has been reported to play a role in the development of human immunodeficiency virus(HIV)-related mal... BACKGROUND Primary non-Hodgkin’s lymphoma of the frontal sinus is extremely rare.In addition,Epstein-Barr virus(EBV)has been reported to play a role in the development of human immunodeficiency virus(HIV)-related malignant lymphomas.To the best of our knowledge,there is no report for the HIVassociated,EBV-positive primary diffuse large B-cell lymphoma(DLBCL)in the frontal sinus.CASE SUMMARY We present a unique case of HIV-associated,EBV-positive DLBCL in the frontal sinus in a 46-year-old man.Computed tomography of paranasal sinuses revealed dense opacification of the right frontal sinus with combined soft tissue swelling.Based on the clinical and radiological findings,the initial diagnosis was complicated frontal sinusitis,presenting Pott’s puffy tumor.Unexpectedly,HIV testing was positive on preoperative laboratory test,and the frontal sinus lesion was confirmed as EBV-positive DLBCL on biopsy.CONCLUSION Through this article,we suggest that EBV-positive DLBCL should be considered as possible diagnosis for patients with nonspecific space-occupying lesion of the paranasal sinuses.We also highlight an importance of clinical suspicion in diagnosing HIV infection because HIV serology is not routinely tested in patients with paranasal sinus problem. 展开更多
关键词 LYMPHOMA paranasal sinus Human immunodeficiency virus Epstein-Barr virus Computed tomography Case report
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A Case of Maxillary Sinus Cholesteatoma Originating from the Retromaxillary Sinus Wall
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作者 Jun Myung Lee Nam Gyu Ryu Ick Soo Choi 《International Journal of Otolaryngology and Head & Neck Surgery》 2015年第5期325-328,共4页
Cholesteatomas are often observed in the middle ear or mastoid cavity. However, cholesteatomas in areas other than the middle ear or mastoid are extremely rare and thus are not often reported in the literature. We rec... Cholesteatomas are often observed in the middle ear or mastoid cavity. However, cholesteatomas in areas other than the middle ear or mastoid are extremely rare and thus are not often reported in the literature. We recently treated an 18-year-old female patient with an incidentally detected maxillary sinus mass. A paranasal sinus computed tomography examination revealed a cystic lesion in the left maxillary sinus infiltrating the posterolateral walls of the left maxillary sinus. An endoscopic operation was performed for definitive diagnosis. Histopathological examination of the mass confirmed the diagnosis of cholesteatoma. Despite the rarity of paranasal cholesteatoma in comparison with cholesteatomas in the tympanum, a few cases involving the frontal sinus have been reported. However, retromaxillary cholesteatoma is even less common than sinus cholesteatoma and is reported rarely. To our knowledge, this is the first reported case of a maxillary cholesteatoma originating from the retromaxillary area. For this reason, we present this case along with a literature review. 展开更多
关键词 CHOLESTEATOMA paranasal sinus Retromaxillary sinus paranasal sinus Computed Tomography
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累及鼻腔鼻窦的Rosai-Dorfman病临床特征分析
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作者 郑铭 司马宇彤 +2 位作者 庄梦岩 王向东 张罗 《中国耳鼻咽喉头颈外科》 CSCD 2024年第4期236-241,共6页
目的探讨累及鼻腔鼻窦的Rosai-Dorfman病(Rosai-Dorfman disease,RDD)的临床特征性表现。方法对2016年12月~2023年8月在首都医科大学附属北京同仁医院鼻科接受诊治的16例累及鼻腔鼻窦的RDD患者的临床资料回顾性分析。结果男女比例1∶3,... 目的探讨累及鼻腔鼻窦的Rosai-Dorfman病(Rosai-Dorfman disease,RDD)的临床特征性表现。方法对2016年12月~2023年8月在首都医科大学附属北京同仁医院鼻科接受诊治的16例累及鼻腔鼻窦的RDD患者的临床资料回顾性分析。结果男女比例1∶3,平均年龄47.4岁,平均病程22.34个月。主诉鼻塞、鼻干、嗅觉减退、头面部痛和突眼/复视的患者,分别有14、3、5、6和1例,9例存在外鼻肿胀。14例至少累及鼻中隔,12例单纯鼻腔受累,3例累及鼻窦,1例为混合型。10例行快速冰冻病理检查,8例结果误诊或漏诊。鼻内镜检查9例患者的鼻中隔呈现双侧膨隆,7例鼻底和下鼻甲表面有结节状隆起或者颗粒状新生物。鼻窦CT发现9例患者鼻中隔区域呈现类圆形均匀软组织影或对称性软组织增厚影,5例鼻底、下鼻甲呈现明显的软组织增厚影。结论累及鼻腔鼻窦的RDD在外鼻表现、内镜和影像学检查中有一定的典型特征,综合判断有助于提高临床诊断RDD的可行性。 展开更多
关键词 鼻腔 鼻窦疾病 诊断 计算机辅助 ROSAI-DORFMAN病 临床特征 影像学
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计算机体层成像对嗅窝深度的Keros分类及评估
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作者 陈靓 王琪 +1 位作者 胡静 徐凯 《中国医学计算机成像杂志》 CSCD 北大核心 2024年第3期289-292,F0002,共5页
目的:根据Keros分类,使用CT对嗅窝深度进行评估,并探讨成人两侧嗅窝深度的差异。方法:对2022年6月至2023年3月进行副鼻窦CT平扫的521例患者进行回顾性研究,使用PACS软件在冠状位上测量筛板与筛顶之间的垂直距离进行分类及评估。结果:104... 目的:根据Keros分类,使用CT对嗅窝深度进行评估,并探讨成人两侧嗅窝深度的差异。方法:对2022年6月至2023年3月进行副鼻窦CT平扫的521例患者进行回顾性研究,使用PACS软件在冠状位上测量筛板与筛顶之间的垂直距离进行分类及评估。结果:1042侧嗅窝中,KerosⅡ型最常见,其次是Ⅲ型,然后是Ⅰ型。嗅窝平均深度左、右两侧差异有统计学意义,男、女之间差异有统计学意义(均P<0.05)。根据性别比较,右侧嗅窝平均深度在不同性别之间差异无统计学意义(P>0.05),左侧则差异有统计学意义(P<0.05)。左右两侧嗅窝Keros分类在男、女之间差异均无统计学意义(P>0.05)。结论:成人两侧及不同性别之间的嗅窝深度存在差异,术前对副鼻窦进行CT扫描对于外科医生评估前颅底的解剖、确保手术入路的正确规划和预防相关可能的手术并发症至关重要。 展开更多
关键词 鼻内窥镜手术 计算机体层成像 副鼻窦 嗅窝 Keros分类
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鼻内镜手术辅助低温等离子射频消融术对鼻腔鼻窦内翻性乳头状瘤患者鼻功能、复发率的影响
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作者 武新荣 卢美美 赵勇 《黑龙江医学》 2024年第16期1936-1939,共4页
目的:探讨鼻内镜手术辅助低温等离子射频消融术治疗对鼻腔鼻窦内翻性乳头状瘤(SNIP)患者鼻功能、复发率的影响。方法:选取2021年3月—2022年3月焦作煤业(集团)有限责任公司中央医院收治的80例SNIP患者作为研究对象,采用随机数表法将其... 目的:探讨鼻内镜手术辅助低温等离子射频消融术治疗对鼻腔鼻窦内翻性乳头状瘤(SNIP)患者鼻功能、复发率的影响。方法:选取2021年3月—2022年3月焦作煤业(集团)有限责任公司中央医院收治的80例SNIP患者作为研究对象,采用随机数表法将其分为两组,每组各40例。对照组予以低温等离子射频消融术治疗,观察组予以鼻内镜手术辅助低温等离子射频消融术治疗,比较两组患者鼻功能、复发率。结果:术后3个月,两组患者鼻腔最小横截面积(NMCA)、鼻腔容积(NCV)升高,鼻阻力降低,且观察组NMCA、NCV高于对照组,鼻阻力低于对照组,差异均有统计学意义(t=3.343、5.806、4.326,P<0.05);两组患者纤毛清除速度、黏液纤毛清除率升高,糖精清除时间减少,且观察组纤毛清除速度、黏液纤毛清除率高于对照组,糖精清除时间短于对照组,差异均有统计学意义(t=6.647、4.088、5.320,P<0.05);两组患者息肉、水肿、分泌物评分降低,且观察组息肉、水肿、分泌物评分低于对照组,差异均有统计学意义(t=4.420、8.854、5.935,P<0.05);两组患者生理问题、健康相关生活质量评分降低,且观察组生理问题、健康相关生活质量评分低于对照组,差异均有统计学意义(t=3.539、3.621,P<0.05)。随访1年发现,观察组术后复发率(2.50%)低于对照组(20.00%),差异有统计学意义(χ^(2)=4.507,P=0.034)。结论:鼻内镜手术辅助低温等离子射频消融术治疗对SNIP患者鼻功能改善效果更佳,且能降低复发率,减轻临床症状,提高生活质量。 展开更多
关键词 鼻腔鼻窦内翻性乳头状瘤 鼻内镜 低温等离子射频消融术 鼻功能
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鼻腔鼻窦神经鞘瘤CT及MRI表现
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作者 郝胜璞 王宁 +3 位作者 高国栋 王佳鑫 包文君 耿左军 《中国医学影像技术》 CSCD 北大核心 2023年第3期342-345,共4页
目的观察鼻腔鼻窦神经鞘瘤CT及MRI表现。方法回顾性分析13例经病理证实的鼻腔鼻窦神经鞘瘤患者,包括12例良性、1例恶性病变;13例均接受平扫、2例接受增强CT扫描;10例接受平扫、6例接受平扫及增强MR扫描;观察病灶CT及MRI表现。结果13例... 目的观察鼻腔鼻窦神经鞘瘤CT及MRI表现。方法回顾性分析13例经病理证实的鼻腔鼻窦神经鞘瘤患者,包括12例良性、1例恶性病变;13例均接受平扫、2例接受增强CT扫描;10例接受平扫、6例接受平扫及增强MR扫描;观察病灶CT及MRI表现。结果13例均为单发病灶,平扫CT呈不均匀软组织密度(n=11)或稍低密度(n=2),5个病灶内见不规则低密度区;8例累及鼻腔及鼻窦,邻近骨质受压变形、吸收,5例局限于鼻腔内;增强CT显示2个病灶(2/2)均呈轻度不均匀强化。10例平扫MRI显示病灶信号不均匀,8个呈等T1WI、T2WI信号,2个呈低T1WI及稍高T2WI信号;9个病灶内见混杂斑片状低T1WI、高T2WI信号,其中5个内见斑点状、条状T1WI及低T2WI信号,6个病灶边缘见不连续T2WI低信号;增强MRI显示6个病灶(6/6)均呈渐进性不均匀强化,其内散在异常信号区呈轻度强化或无强化,4个病灶边缘轻度强化、1个明显强化、1个未强化。结论鼻腔鼻窦神经鞘瘤CT无明显特异性表现,其MRI表现则具有一定特征性。 展开更多
关键词 鼻窦肿瘤 神经鞘瘤 诊断显像
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15例鼻腔鼻窦横纹肌肉瘤的临床分析
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作者 任莹 路晔敏 +5 位作者 陈一博 张志收 张艳廷 安云芳 宋翔 赵长青 《中国耳鼻咽喉颅底外科杂志》 CAS CSCD 2023年第1期38-44,共7页
目的 探讨鼻腔鼻窦横纹肌肉瘤(RMS)的临床特征、治疗方式及预后的影响因素。方法 回顾性分析2012年1月—2022年1月收治的15例鼻腔鼻窦RMS患者资料。15例RMS患者多为青少年,胚胎型12例,腺泡型3例。其中单纯化疗1例,鼻内镜手术+术后化疗3... 目的 探讨鼻腔鼻窦横纹肌肉瘤(RMS)的临床特征、治疗方式及预后的影响因素。方法 回顾性分析2012年1月—2022年1月收治的15例鼻腔鼻窦RMS患者资料。15例RMS患者多为青少年,胚胎型12例,腺泡型3例。其中单纯化疗1例,鼻内镜手术+术后化疗3例,鼻内镜手术+术后放化疗7例,术前诱导化疗+鼻内镜手术+术后放化疗4例。应用SPSS 26.0软件进行描述性统计分析,用Kaplan-Meier法评估患者的临床特征、病理类型、肿瘤分期、治疗方式等因素与临床预后的关系。结果 随访3~113个月。治疗后6例无复发,4例局部复发,5例全身转移。8例生存,7例死亡。1年生存率约为93.3%,5年生存率约为43.6%。病理类型、淋巴结转移、远处转移、治疗方式及美国RMS研究组(IRS)分期是影响RMS预后的危险因素(P<0.05)。结论 鼻腔鼻窦RMS临床罕见,易侵及眼眶、颅底,具有高复发率及死亡率。多学科联合诊疗是目前有效的治疗方式,手术联合辅助放化疗可降低复发率、改善预后。提高对该病的临床及病理认识,进行分子学及基因组学研究,寻找新的治疗靶点,有望提高患者的生活质量及生存率。 展开更多
关键词 鼻腔鼻窦 横纹肌肉瘤 治疗 预后
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副鼻窦肉瘤样癌影像学表现一例
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作者 王媛媛 卢婷 +1 位作者 杨新梅 周俊林 《磁共振成像》 CAS CSCD 北大核心 2023年第10期122-124,共3页
本研究为回顾性研究,遵守《赫尔辛基宣言》,并经兰州大学第二医院伦理委员会审核批准,免除受试者知情同意,批准文号:2023A-362。患者女,73岁,“鼻塞、流涕伴头痛2年”就诊。患者于入院前2年无明显诱因出现双侧鼻腔间断性鼻塞、流涕,右... 本研究为回顾性研究,遵守《赫尔辛基宣言》,并经兰州大学第二医院伦理委员会审核批准,免除受试者知情同意,批准文号:2023A-362。患者女,73岁,“鼻塞、流涕伴头痛2年”就诊。患者于入院前2年无明显诱因出现双侧鼻腔间断性鼻塞、流涕,右侧为著,伴间断性头痛,于外院给予对症治疗后症状无缓解,遂于2023年2月来我院就诊。此次我院专科查体:鼻黏膜充血,右侧中鼻道及下鼻道可见淡粉色肿物,表面光滑,无渗血。 展开更多
关键词 副鼻窦恶性肿瘤 鼻窦癌 肉瘤样癌 计算机体层摄影 磁共振成像
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晚期鼻腔鼻窦恶性肿瘤手术疗效及预后因素研究
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作者 徐海侠 白云飞 +2 位作者 王博谦 刘佳荣 李欣 《中国耳鼻咽喉头颈外科》 CSCD 2023年第12期749-752,共4页
目的 探讨晚期鼻腔鼻窦恶性肿瘤手术疗效及预后因素,旨在为手术方案选择及预后预测评估提供更多参考。方法 回顾性纳入2010年1月~2019年1月于内蒙古医科大学附属医院行手术治疗晚期鼻腔鼻窦恶性肿瘤患者117例,分析临床特征资料和随访生... 目的 探讨晚期鼻腔鼻窦恶性肿瘤手术疗效及预后因素,旨在为手术方案选择及预后预测评估提供更多参考。方法 回顾性纳入2010年1月~2019年1月于内蒙古医科大学附属医院行手术治疗晚期鼻腔鼻窦恶性肿瘤患者117例,分析临床特征资料和随访生存资料,采用单因素和多因素法评估晚期鼻腔鼻窦恶性肿瘤手术预后独立影响因素。结果 117例患者术后随访5年无进展生存率和总生存率分别为48.71%和62.39%,中位无进展生存时间和总生存时间分别为32.48个月和39.80个月。单因素以及多因素分析结果显示,年龄、病理组织学类型、切缘状态及是否接受辅助治疗均是晚期鼻腔鼻窦恶性肿瘤术后无进展生存时间及总生存时间独立影响因素(P均<0.05)。结论 晚期鼻腔鼻窦恶性肿瘤手术疗效良好,且预后与年龄、切缘状态及是否接受辅助治疗有关。 展开更多
关键词 鼻腔 鼻窦肿瘤 外科手术 预后
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Sn100 kV在儿童副鼻窦CT检查中的应用
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作者 朱虹 徐树明 徐长青 《实用医技杂志》 2023年第5期352-355,共4页
目的探讨Sn100 kV在儿童副鼻窦病变的应用,保证诊断效果的同时减少辐射剂量,提高儿童诊断安全性。方法回顾性分析山西省儿童医院2021年12月至2022年2月100例接受CT检查的副鼻窦病变患儿,采用Sn100 kV扫描、常规CT扫描各50例,比较2组图... 目的探讨Sn100 kV在儿童副鼻窦病变的应用,保证诊断效果的同时减少辐射剂量,提高儿童诊断安全性。方法回顾性分析山西省儿童医院2021年12月至2022年2月100例接受CT检查的副鼻窦病变患儿,采用Sn100 kV扫描、常规CT扫描各50例,比较2组图像质量、辐射剂量。2名医师采用Likert 5级量表对图像质量评分,计算其一致性。结果Sn100 kV组容积CT剂量指数(CTDIvol)为0.52 mGy,剂量-长度乘积(DLP)为(7.4±0.6)mGy·cm,有效直径(ED)为(0.03±0.01)mSv,体型特异性剂量评估(SSDE)为(0.55±0.02)mGy,低于常规CT组(2.6±0.4)mGy,(32.9±7.8)mGy·cm,(0.13±0.04)mSv,(2.68±0.26)mGy,分别降低了79.8%,77.5%,76.9%,79.5%,差异有统计学意义(P<0.001)。骨窗、软窗眶内脂肪和玻璃体信号与干扰加噪声比(SNR)差异均有统计学意义(P<0.001),但仍满足诊断要求。2名医师间图像质量一致性为83.8%。结论Sn100 kV扫描在不影响临床诊断的情况下,可以有效降低辐射剂量。 展开更多
关键词 鼻窦疾病 辐射暴露 体层摄影术 螺旋计算机
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低管电压联合快速迭代重建技术在副鼻窦CT检查中的应用
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作者 胡文业 郭文强 《山西大同大学学报(自然科学版)》 2023年第5期75-77,共3页
目的 探讨多排螺旋CT低管电压(80 kV)扫描联合快速迭代重建技术在副鼻窦扫描中的应用。方法将100例副鼻窦CT检查的患者分为80 kV扫描联合快速迭代重建技术(A组),120 kV扫描(B组)滤波反投影重建;比较两组图像质量主观评分、图像平均值、... 目的 探讨多排螺旋CT低管电压(80 kV)扫描联合快速迭代重建技术在副鼻窦扫描中的应用。方法将100例副鼻窦CT检查的患者分为80 kV扫描联合快速迭代重建技术(A组),120 kV扫描(B组)滤波反投影重建;比较两组图像质量主观评分、图像平均值、图像噪声、SNR、CNR、辐射剂量等指标的差异。结果 A、B两组图像的主观评分比较差异无统计学意义(P>0.05);A组图像CT平均值、图像噪声略低于B组,SNR及CNR高于B组,但差异无统计学意义(P>0.05);A组辐射剂量均低于B组,差异有统计学意义(P<0.05)。结论 多排螺旋CT低管电压(80 kV)扫描联合快速迭代重建技术进行副鼻窦检查,能保证图像诊断质量,并可降低辐射剂量。 展开更多
关键词 低管电压 快速迭代重建技术 副鼻窦 辐射剂量
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Sex Predictive Value of Frontal Sinus Index Compared to Maxillary Sinus Index:Lateral Cephalometric Study
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作者 Fatma Mohamed Hassan Maged Nabil Hussein +1 位作者 Noran Ayman Abdel Motagally Walaa Samir 《Journal of Forensic Science and Medicine》 2023年第2期162-166,共5页
Sex estimation is a crucial step to outline the biological profile of unknown human remains.The frontal and maxillary sinuses have unique anatomical features and can be utilized efficiently in individual identificatio... Sex estimation is a crucial step to outline the biological profile of unknown human remains.The frontal and maxillary sinuses have unique anatomical features and can be utilized efficiently in individual identification.Previous studies investigated the frontal and maxillary sinus indexes separately for sex prediction.However,comparing the predictive value of the frontal sinus index(FSI)to the maxillary sinus index(MSI)has not been investigated yet.This study aimed to evaluate the sex predicting value of FSI compared to MSI assessed on digital lateral cephalometry.This retrospective cross-sectional study included 88 digital lateral cephalometric images of known sex(44 males and 44 females)and age(20-50 years).Two radiologists measured the maximum anteroposterior sinus width and height of the frontal sinus and maxillary sinus.Then,the sinus index was calculated for each radiograph.The obtained frontal and maxillary sinuses parameters were tabulated,along with the patient’s sex and age,and subjected to statistical analysis.Our results revealed significant differences between males and females regarding frontal sinus width,FSI,and MSI.The discriminant function analysis obtained in this study accurately predicted sex with an overall accuracy of 71.6%(81.8%of males and 61.4%of females)using FSI,and 60.2%(63.6%in females and 56.8%in males)using MSI.Frontal and maxillary sinus indexes can be useful tools for sex prediction.Discriminant function equations were developed for both the frontal and maxillary sinus indexes with higher accuracy rates for FSI compared to MSI. 展开更多
关键词 CEPHALOMETRY discriminant analysis paranasal sinuses sex prediction sinus index
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鼻内镜辅助上颌骨部分切除术治疗鼻腔鼻窦腺样囊性癌的临床分析
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作者 邹文焘 周月 +2 位作者 蔡晓菁 周双 张家雄 《中国中西医结合耳鼻咽喉科杂志》 2023年第2期94-97,共4页
目的观察分析鼻内镜辅助上颌骨部分切除术治疗鼻腔鼻窦腺样囊性癌的临床应用效果。方法回顾性分析我科在2016年5月~2018年5月经病理确诊的13例鼻腔鼻窦腺样囊性癌患者的临床资料,总结分析鼻内镜辅助上颌骨部分切除术治疗本病的临床疗效... 目的观察分析鼻内镜辅助上颌骨部分切除术治疗鼻腔鼻窦腺样囊性癌的临床应用效果。方法回顾性分析我科在2016年5月~2018年5月经病理确诊的13例鼻腔鼻窦腺样囊性癌患者的临床资料,总结分析鼻内镜辅助上颌骨部分切除术治疗本病的临床疗效。结果13例患者中,6例病变累及上颌窦,采用鼻内镜辅助上颌骨部分切除术切除肿瘤,获得良好手术视野,顺利完成肿瘤切除。与传统开放式上颌骨切除术相比较,手术范围更为精确,创伤较小,术后患者恢复较快。结论鼻内镜辅助上颌骨部分切除术治疗鼻腔鼻窦腺样囊性癌的临床应用效果较好。 展开更多
关键词 腺样囊性癌 鼻腔鼻窦 鼻内镜鼻窦手术 上颌骨部分切除术 临床应用
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鼻内镜下泪前隐窝入路微创治疗累及上颌窦的复杂内翻性乳头状瘤 被引量:17
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作者 贾弘光 李希平 +3 位作者 于湛 王建宏 魏鹏 魏永祥 《中国微创外科杂志》 CSCD 北大核心 2017年第6期546-549,564,共5页
目的探讨经鼻内镜泪前隐窝入路微创治疗累及上颌窦的复杂内翻性乳头状瘤的可行性及疗效。方法回顾性分析2013年1月~2015年10月18例经鼻内镜泪前隐窝入路手术治疗累及上颌窦的复杂内翻性乳头状瘤的临床资料,男14例,女4例,年龄17~73岁,平... 目的探讨经鼻内镜泪前隐窝入路微创治疗累及上颌窦的复杂内翻性乳头状瘤的可行性及疗效。方法回顾性分析2013年1月~2015年10月18例经鼻内镜泪前隐窝入路手术治疗累及上颌窦的复杂内翻性乳头状瘤的临床资料,男14例,女4例,年龄17~73岁,平均49.3岁。术前行CT、MRI检查,明确病变累及泪前隐窝、齿槽隐窝并伴有上颌窦各壁多发骨质破坏。经鼻内镜泪前隐窝入路清除上颌窦内病变,处理肿瘤根蒂处黏膜并清除受累骨质,视病变范围处理筛窦、蝶窦、额窦。术后定期鼻内镜检查随访,观察症状改善、并发症及肿瘤原位复发、远处转移情况。结果 18例均顺利完成手术,术后经鼻内镜检查、换药,随访6~40个月,平均24个月。9例术后患侧鼻腔通气改善,头痛等临床症状消失,鼻内镜检查窦腔上皮化,无视力下降、复视、溢泪等并发症发生;5例术后囊泡或肉芽增生,经鼻内镜换药2~4周消失;2例病理提示伴癌变,术后放射治疗,随访9、13个月未见复发及远处转移;2例术后复发,经再次鼻内镜手术,扩大切除病变,分别继续随访12、15个月未见复发。结论泪前隐窝入路治疗复杂上颌窦内翻性乳头状瘤,可彻底清除上颌窦病灶,手术损伤小,术后并发症少,是可行的手术方式。 展开更多
关键词 乳头状瘤 内翻 鼻窦 内镜
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