目的探讨强化降压与标准降压治疗老年高血压合并冠心病患者经皮冠状动脉介入术(PCI)术后的效果及安全性。方法86例老年高血压合并冠心病PCI患者以随机数字表法分为对照组和研究组,每组43例。对照组给予标准降压治疗[目标收缩压(SBP)<...目的探讨强化降压与标准降压治疗老年高血压合并冠心病患者经皮冠状动脉介入术(PCI)术后的效果及安全性。方法86例老年高血压合并冠心病PCI患者以随机数字表法分为对照组和研究组,每组43例。对照组给予标准降压治疗[目标收缩压(SBP)<135 mmHg],研究组给予强化降压治疗(目标SBP<120 mmHg),自治疗起始随访12个月观察效果。记录2组患者治疗前后的24 h SBP和舒张压(DBP)变异系数;采用超声心动图评价治疗前后心功能改变;采用欧洲五维健康评价量表(EQ-5D-3L)中的视觉模拟量表评价健康状况,采用患者健康问卷抑郁量表(PHQ-9)评价抑郁情绪,采用焦虑自评量表(SAS)评价焦虑情绪,采用国际版跌倒效能量表(FES-I)评价跌倒风险。结果2组患者治疗前24 h SBP及24 h DBP变异系数、左心室射血分数(LVEF)、左心室质量指数(LVMI)、左心房容积指数(LAVI)、EQ-5D-3L得分、PHQ-9得分、SAS得分、FES-I得分差异均无统计学意义(P>0.05);研究组治疗后的24 h SBP、24 h DBP变异系数、LAVI、PHQ-9得分、SAS得分及FES-I得分均低于对照组,LVEF、LVMI、EQ-5D-3L得分高于对照组(P<0.05);研究组、对照组治疗期间总不良反应发生率比较差异无统计学意义(P>0.05);研究组心脑血管新发事件总发生率低于对照组(P<0.05)。结论强化降压治疗在降低老年高血压合并冠心病患者PCI术后的24 h血压变异系数、改善心功能方面优于标准降压治疗,可提高患者生活质量,且安全性良好。展开更多
In large fusion experiments, such as tokamak devices, there is a common trendfor slow control systems. Because of complexity of the plants, the so-called 'Standard Model' (SM)in slow control has been adopted o...In large fusion experiments, such as tokamak devices, there is a common trendfor slow control systems. Because of complexity of the plants, the so-called 'Standard Model' (SM)in slow control has been adopted on several tokamak machines. This model is based on a three-levelhierarchical control: 1) High-Level Control (HLC) with a supervisory function; 2) Medium-LevelControl (MLC) to interface and concentrate I/O field equipments; 3) Low-Level Control (LLC) withhard real-time I/O function, often managed by PLCs. FTU control system designed with SM concepts hasunderwent several stages of developments in its fifteen years duration of runs. The latestevolution was inevitable, due to the obsolescence of the MLC CPUs, based on VME-MOTOROLA 68030 withOS9 operating system. A large amount of C code was developed for that platform to route the dataflow from LLC, which is constituted by 24 Westinghouse Numalogic PC-700 PLCs with about 8000field-points, to HLC, based on a commercial Object-Oriented Real-Time database on Alpha/CompaqTru64platform. Therefore, we have to look for cost-effective solutions and finally a CompactPCI—Intelx86 platform with Linux operating system was chosen. A software porting has been done, taking intoaccount the differences between OS9 and Linux operating system in terms of Inter/Network ProcessesCommunications and I/O multi-ports serial driver. This paper describes the hardware/softwarearchitecture of the new MLC system, emphasizing the reliability and the low costs of the open sourcesolutions. Moreover, a huge amount of software packages available in open source environment willassure a less painful maintenance, and will open the way to further improvements of the systemitself.展开更多
文摘目的探讨强化降压与标准降压治疗老年高血压合并冠心病患者经皮冠状动脉介入术(PCI)术后的效果及安全性。方法86例老年高血压合并冠心病PCI患者以随机数字表法分为对照组和研究组,每组43例。对照组给予标准降压治疗[目标收缩压(SBP)<135 mmHg],研究组给予强化降压治疗(目标SBP<120 mmHg),自治疗起始随访12个月观察效果。记录2组患者治疗前后的24 h SBP和舒张压(DBP)变异系数;采用超声心动图评价治疗前后心功能改变;采用欧洲五维健康评价量表(EQ-5D-3L)中的视觉模拟量表评价健康状况,采用患者健康问卷抑郁量表(PHQ-9)评价抑郁情绪,采用焦虑自评量表(SAS)评价焦虑情绪,采用国际版跌倒效能量表(FES-I)评价跌倒风险。结果2组患者治疗前24 h SBP及24 h DBP变异系数、左心室射血分数(LVEF)、左心室质量指数(LVMI)、左心房容积指数(LAVI)、EQ-5D-3L得分、PHQ-9得分、SAS得分、FES-I得分差异均无统计学意义(P>0.05);研究组治疗后的24 h SBP、24 h DBP变异系数、LAVI、PHQ-9得分、SAS得分及FES-I得分均低于对照组,LVEF、LVMI、EQ-5D-3L得分高于对照组(P<0.05);研究组、对照组治疗期间总不良反应发生率比较差异无统计学意义(P>0.05);研究组心脑血管新发事件总发生率低于对照组(P<0.05)。结论强化降压治疗在降低老年高血压合并冠心病患者PCI术后的24 h血压变异系数、改善心功能方面优于标准降压治疗,可提高患者生活质量,且安全性良好。
文摘In large fusion experiments, such as tokamak devices, there is a common trendfor slow control systems. Because of complexity of the plants, the so-called 'Standard Model' (SM)in slow control has been adopted on several tokamak machines. This model is based on a three-levelhierarchical control: 1) High-Level Control (HLC) with a supervisory function; 2) Medium-LevelControl (MLC) to interface and concentrate I/O field equipments; 3) Low-Level Control (LLC) withhard real-time I/O function, often managed by PLCs. FTU control system designed with SM concepts hasunderwent several stages of developments in its fifteen years duration of runs. The latestevolution was inevitable, due to the obsolescence of the MLC CPUs, based on VME-MOTOROLA 68030 withOS9 operating system. A large amount of C code was developed for that platform to route the dataflow from LLC, which is constituted by 24 Westinghouse Numalogic PC-700 PLCs with about 8000field-points, to HLC, based on a commercial Object-Oriented Real-Time database on Alpha/CompaqTru64platform. Therefore, we have to look for cost-effective solutions and finally a CompactPCI—Intelx86 platform with Linux operating system was chosen. A software porting has been done, taking intoaccount the differences between OS9 and Linux operating system in terms of Inter/Network ProcessesCommunications and I/O multi-ports serial driver. This paper describes the hardware/softwarearchitecture of the new MLC system, emphasizing the reliability and the low costs of the open sourcesolutions. Moreover, a huge amount of software packages available in open source environment willassure a less painful maintenance, and will open the way to further improvements of the systemitself.
