Seasonal and interannual variability of ocean bottom pressure(OBP)in the Southern Ocean was investigated using Gravity Recovery and Climate Experiment(GRACE)data and a Pressure Coordinate Ocean Model(PCOM)based on mas...Seasonal and interannual variability of ocean bottom pressure(OBP)in the Southern Ocean was investigated using Gravity Recovery and Climate Experiment(GRACE)data and a Pressure Coordinate Ocean Model(PCOM)based on mass conservation.By comparing OBP,steric sea level,and sea level,it is found that at high latitudes the OBP variability dominates the sea level variability at seasonal-to-decadal time scales.The diagnostic OBP based on barotropic vorticity equation has a good correlation with the observations,indicating that wind forcing plays an important role in the variability of the OBP in the Southern Ocean.The unique interannual patterns of OBP in the Southern Ocean are closely associated with El Niño-Southern Oscillation(ENSO)and Southern Annular Mode(SAM).Regression analysis indicates that ENSO and SAM influence the OBP through altering the Ekman transport driven by surface wind.The leading pattern of OBP from PCOM are very similar to observations.Sensitive experiments of PCOM show that surface wind forcing explains the observed OBP variability quite well,confirming the importance of wind forcing and related oceanic processes.In the eastern South Pacific,the averaged OBP shows a decrease(increase)trend before(after)2011,reflecting the reverse trend in westerly wind.In the South Indo-Atlantic Ocean,the averaged OBP has a weak increase trend during 2003–2016.展开更多
Objective To evaluate the differences of the clinical manifestation and endocrine situation in patients with different ovarian morphology of polycystic ovary syndrome （PCOS）. Methods A total of 234 PCOS patients wer...Objective To evaluate the differences of the clinical manifestation and endocrine situation in patients with different ovarian morphology of polycystic ovary syndrome （PCOS）. Methods A total of 234 PCOS patients were enrolled according to the ovary morphology and divided into three groups： 112 patients with B-polycystic ovary mor- phology （both two ovaries were PCOM, B-PCOM）, 50 with U-PCOM （only one ovary was PCOM） and 72 with N-PCOM （none was PCOM）. There were 39 infertile women without PCOS as control group. Data were analyzed by using SPSS 15.0 software. ResuIts There was no statistical difference in body mass index （BM1） among the three groups of PCOS. The endometrial thickness increased in patients with B-PCOM and decreased with N-PCOM. The levels of testosterone, androstenedione and luteinizing hormone increased in PCOS groups, especially in N-PCOM patients. HOMA-IR increased, HOMA-fl, disposition index （DI） and △160/AG60 decreased in patients with N- PCOM compared with in B-PCOM and U-PCOM groups. Higher level of total choles- terol （TC） and lower level of high-density lipoprotein （HDL）-C existed in PCOS patients, especially in N-PCOM. There were positive correlations between oligo-anovulation, endometrial thickness, LH/FSH ratio, fasting insulin （FINS）, the area under curve of glucose（A UCcLu） and PCOM, while there was a negative correlation between HOMA- IR and PCOM. Conclusion There are relationships among hyperandrogenism, hyperinsulinemia, insulin resistance （IR） and ovary morphology in PCOS patients. PCOS patients with- out PCOM have more serious IR and hyperandrogenism.展开更多
基金The National Key R&D Program of China under contract No.2018YFA0605703the National Natural Science Foundation of China under contract Nos 41876002 and 41876224.
文摘Seasonal and interannual variability of ocean bottom pressure(OBP)in the Southern Ocean was investigated using Gravity Recovery and Climate Experiment(GRACE)data and a Pressure Coordinate Ocean Model(PCOM)based on mass conservation.By comparing OBP,steric sea level,and sea level,it is found that at high latitudes the OBP variability dominates the sea level variability at seasonal-to-decadal time scales.The diagnostic OBP based on barotropic vorticity equation has a good correlation with the observations,indicating that wind forcing plays an important role in the variability of the OBP in the Southern Ocean.The unique interannual patterns of OBP in the Southern Ocean are closely associated with El Niño-Southern Oscillation(ENSO)and Southern Annular Mode(SAM).Regression analysis indicates that ENSO and SAM influence the OBP through altering the Ekman transport driven by surface wind.The leading pattern of OBP from PCOM are very similar to observations.Sensitive experiments of PCOM show that surface wind forcing explains the observed OBP variability quite well,confirming the importance of wind forcing and related oceanic processes.In the eastern South Pacific,the averaged OBP shows a decrease(increase)trend before(after)2011,reflecting the reverse trend in westerly wind.In the South Indo-Atlantic Ocean,the averaged OBP has a weak increase trend during 2003–2016.
文摘Objective To evaluate the differences of the clinical manifestation and endocrine situation in patients with different ovarian morphology of polycystic ovary syndrome （PCOS）. Methods A total of 234 PCOS patients were enrolled according to the ovary morphology and divided into three groups： 112 patients with B-polycystic ovary mor- phology （both two ovaries were PCOM, B-PCOM）, 50 with U-PCOM （only one ovary was PCOM） and 72 with N-PCOM （none was PCOM）. There were 39 infertile women without PCOS as control group. Data were analyzed by using SPSS 15.0 software. ResuIts There was no statistical difference in body mass index （BM1） among the three groups of PCOS. The endometrial thickness increased in patients with B-PCOM and decreased with N-PCOM. The levels of testosterone, androstenedione and luteinizing hormone increased in PCOS groups, especially in N-PCOM patients. HOMA-IR increased, HOMA-fl, disposition index （DI） and △160/AG60 decreased in patients with N- PCOM compared with in B-PCOM and U-PCOM groups. Higher level of total choles- terol （TC） and lower level of high-density lipoprotein （HDL）-C existed in PCOS patients, especially in N-PCOM. There were positive correlations between oligo-anovulation, endometrial thickness, LH/FSH ratio, fasting insulin （FINS）, the area under curve of glucose（A UCcLu） and PCOM, while there was a negative correlation between HOMA- IR and PCOM. Conclusion There are relationships among hyperandrogenism, hyperinsulinemia, insulin resistance （IR） and ovary morphology in PCOS patients. PCOS patients with- out PCOM have more serious IR and hyperandrogenism.
