Protein drugs are increasingly used in the clinical treatment of various diseases including cancer and infectious diseases because of their specificity and high biological activity[1]. Nevertheless, the efficacy of pr...Protein drugs are increasingly used in the clinical treatment of various diseases including cancer and infectious diseases because of their specificity and high biological activity[1]. Nevertheless, the efficacy of protein drugs is constrained by their relatively short in vivo circulation half-life [2].As a result,frequent administration at high concentrations is often required,leading to undesirable side effects and poor patient compliance [3].展开更多
文摘Protein drugs are increasingly used in the clinical treatment of various diseases including cancer and infectious diseases because of their specificity and high biological activity[1]. Nevertheless, the efficacy of protein drugs is constrained by their relatively short in vivo circulation half-life [2].As a result,frequent administration at high concentrations is often required,leading to undesirable side effects and poor patient compliance [3].
