The 15th Power Systems Computation Conference (PSCC'05) will take place in Liege, Belgium,August 22-26, 2005. PSCC has developed into one of the premier conferences in the area. The emphasis is on both theoretical...The 15th Power Systems Computation Conference (PSCC'05) will take place in Liege, Belgium,August 22-26, 2005. PSCC has developed into one of the premier conferences in the area. The emphasis is on both theoretical developments as well as practical applications in the utility and manufacturing industries.展开更多
)The 2008 IEEE World Congress on Computational Intelligence (WCCI 2008) will be held at the HongKong Convention and Exhibition Centre during June 1-6, 2008. WCCI 2008 will be the fifth milestone inthis series with a g...)The 2008 IEEE World Congress on Computational Intelligence (WCCI 2008) will be held at the HongKong Convention and Exhibition Centre during June 1-6, 2008. WCCI 2008 will be the fifth milestone inthis series with a glorious history from WCCI 1994 in Orlando, WCCI 1998 in Anchorage, WCCI 2002in Honolulu, to WCCI 2006 in Vancouver. Sponsored by the IEEE Computational Intelligence Society,展开更多
Organizer,date and venueThe Second World Conference on Digestology will beheld in the Beijing International Convention Center,Beijing,China on September 8-11,2000 by World Journal ofGastroenterology and World Chinese ...Organizer,date and venueThe Second World Conference on Digestology will beheld in the Beijing International Convention Center,Beijing,China on September 8-11,2000 by World Journal ofGastroenterology and World Chinese Journal of Digestologyand the Committee of World Digestology Network (http://www.wd.org.cn).About 2000 participants are expected toattend the meeting.展开更多
Organizer,date and venueThe Second World Conference on Digestology will beheld in the Beijing International Convention Center,Beijing,China on September 8-11,2000 by World Journal ofGastroenterology and World Chinese ...Organizer,date and venueThe Second World Conference on Digestology will beheld in the Beijing International Convention Center,Beijing,China on September 8-11,2000 by World Journal ofGastroenterology and World Chinese Journal of Digestologyand the Committee of World Digestology Network(http://www.wd.org.cn).About 2000 participants are expected toattend the meeting.展开更多
Conference Theme Advanced Technologies for Emergency Planning and ResponseThe 2008 IEEE International Conference on Networking, Sensing and Control will be held in Sanya,China. The main theme of the conference is adva...Conference Theme Advanced Technologies for Emergency Planning and ResponseThe 2008 IEEE International Conference on Networking, Sensing and Control will be held in Sanya,China. The main theme of the conference is advanced technologies for emergency planning and re-展开更多
Previous studies have reported a neuroprotective effect of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) against traumatic brain injury. In accordance with the Marmarou method, rat models of diffuse axonal in...Previous studies have reported a neuroprotective effect of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) against traumatic brain injury. In accordance with the Marmarou method, rat models of diffuse axonal injury were established. 8-OH-DPAT was intraperitoneally injected into model rats. 8-OH-DPAT treated rats maintained at constant temperature served as normal temperature controls TUNEL results revealed that neural cell swelling, brain tissue necrosis and cell apoptosis occurred around the injured tissue. Moreover, the number of Bax-, Bcl-2- and caspase-3-positive cells increased at 6 hours after diffuse axonal injury, and peaked at 24 hours. However, brain injury was attenuated, the number of apoptotic cells reduced, Bax and caspase-3 expression decreased, and Bcl-2 expression increased at 6, 12, 24, 72 and 168 hours after diffuse axonal injury in normal temperature control and in 8-OH-DPAT-intervention rats. The difference was most significant at 24 hours. All indices in 8-OH-DPAT-intervention rats were better than those in the constant temperature group. These results suggest that 8-OH-DPAT inhibits Bax and caspase-3 expression, increases Bcl-2 expression, and reduces neural cell apoptosis, resulting in neuroprotection against diffuse axonal injury. This effect is associated with a decrease in brain temperature.展开更多
In this study, we treated PC12 cells with 0-20 μM amyloid-β peptide (25-35) for 24 hours to induce cytotoxicity, and found that 5-20 μM amyloid-β peptide (25-35) decreased PC12 cell viability, but adenosine tr...In this study, we treated PC12 cells with 0-20 μM amyloid-β peptide (25-35) for 24 hours to induce cytotoxicity, and found that 5-20 μM amyloid-β peptide (25-35) decreased PC12 cell viability, but adenosine triphosphate-sensitive potassium channel activator diazoxide suppressed the decrease in PC12 cell viability induced by amyloid-β peptide (25-35). Diazoxide protected PC12 cells against amyloid-β peptide (25-35)-induced increases in mitochondrial membrane potential and intracellular reactive oxygen species levels. These protective effects were reversed by the selective mitochondrial adenosine triphosphate-sensitive potassium channel blocker 5-hydroxydecanoate. An inducible nitric oxide synthase inhibitor, Nw-nitro-L-arginine, also protected PC12 cells from amyloid-β peptide (25-35)-induced increases in both mitochondrial membrane potential and intracellular reactive oxygen species levels. However, the H202-degrading enzyme catalase could not reverse the amyloid-β peptide (25-35)-induced increase in intracellular reactive oxygen species. A 24-hour exposure to amyloid-13 peptide (25-35) did not result in apoptosis or necrosis, suggesting that the increases in both mitochondrial membrane potential and reactive oxygen species levels preceded cell death. The data suggest that amyloid-β peptide (25-35) cytotoxicity is associated with adenosine triphosphate-sensitive potassium channels and nitric oxide. Regulation of adenosine triphosphate-sensitive potassium channels suppresses PC12 cell cytotoxicity induced by amyloid-β peptide (25-35).展开更多
This study was aimed to construct a biodegradable but reliable 3-β-hydroxybutymte biosensor. In this context a versatile paper based biosensor, quickly, easily and cheaply fabricated is reported. The procedure of fab...This study was aimed to construct a biodegradable but reliable 3-β-hydroxybutymte biosensor. In this context a versatile paper based biosensor, quickly, easily and cheaply fabricated is reported. The procedure of fabrication is based on the assumption that the introduction of the enzyme in the carbon ink will allow enzyme stabilization and facilitate the study of the catalysis of enzymes and the detection of substrates. To prove this concept we use the enzyme 3-hydroxybutyrate dehydrogenase, in aqueous solution. This enzyme was chosen because it catalyzes the 3-β-hydroxybutyrate, which results from ketoacidosis. The quantification this substance in the diabetics' blood is very important as it can increase the reliability of the diagnosis of glycaemia. To prove the multi-use of this biosensor we not only study the redox process in steady state and during the catalytic process, but also detected and quantify the 3-β-hydroxybutyrate. Our results showed that it was possible to study the redox process that occurred during the catalysis and to confirm the amino acid residues that participate in it. It was also observed that glucose and ascorbic acid can interfere in the detection and quantification of the 3-β-hydroxybutyrate, what should be in mind when the quantification of the 3-β-hydroxybutyrate is made in blood samples.展开更多
文摘The 15th Power Systems Computation Conference (PSCC'05) will take place in Liege, Belgium,August 22-26, 2005. PSCC has developed into one of the premier conferences in the area. The emphasis is on both theoretical developments as well as practical applications in the utility and manufacturing industries.
文摘)The 2008 IEEE World Congress on Computational Intelligence (WCCI 2008) will be held at the HongKong Convention and Exhibition Centre during June 1-6, 2008. WCCI 2008 will be the fifth milestone inthis series with a glorious history from WCCI 1994 in Orlando, WCCI 1998 in Anchorage, WCCI 2002in Honolulu, to WCCI 2006 in Vancouver. Sponsored by the IEEE Computational Intelligence Society,
文摘Organizer,date and venueThe Second World Conference on Digestology will beheld in the Beijing International Convention Center,Beijing,China on September 8-11,2000 by World Journal ofGastroenterology and World Chinese Journal of Digestologyand the Committee of World Digestology Network (http://www.wd.org.cn).About 2000 participants are expected toattend the meeting.
文摘Organizer,date and venueThe Second World Conference on Digestology will beheld in the Beijing International Convention Center,Beijing,China on September 8-11,2000 by World Journal ofGastroenterology and World Chinese Journal of Digestologyand the Committee of World Digestology Network(http://www.wd.org.cn).About 2000 participants are expected toattend the meeting.
文摘Conference Theme Advanced Technologies for Emergency Planning and ResponseThe 2008 IEEE International Conference on Networking, Sensing and Control will be held in Sanya,China. The main theme of the conference is advanced technologies for emergency planning and re-
基金funded by the Natural Science Foundation of Technology Department of Liaoning Province, No.20032047
文摘Previous studies have reported a neuroprotective effect of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) against traumatic brain injury. In accordance with the Marmarou method, rat models of diffuse axonal injury were established. 8-OH-DPAT was intraperitoneally injected into model rats. 8-OH-DPAT treated rats maintained at constant temperature served as normal temperature controls TUNEL results revealed that neural cell swelling, brain tissue necrosis and cell apoptosis occurred around the injured tissue. Moreover, the number of Bax-, Bcl-2- and caspase-3-positive cells increased at 6 hours after diffuse axonal injury, and peaked at 24 hours. However, brain injury was attenuated, the number of apoptotic cells reduced, Bax and caspase-3 expression decreased, and Bcl-2 expression increased at 6, 12, 24, 72 and 168 hours after diffuse axonal injury in normal temperature control and in 8-OH-DPAT-intervention rats. The difference was most significant at 24 hours. All indices in 8-OH-DPAT-intervention rats were better than those in the constant temperature group. These results suggest that 8-OH-DPAT inhibits Bax and caspase-3 expression, increases Bcl-2 expression, and reduces neural cell apoptosis, resulting in neuroprotection against diffuse axonal injury. This effect is associated with a decrease in brain temperature.
基金supported by the Project Sponsored by Yantai Science and Technology Bureau,China,No.2010232
文摘In this study, we treated PC12 cells with 0-20 μM amyloid-β peptide (25-35) for 24 hours to induce cytotoxicity, and found that 5-20 μM amyloid-β peptide (25-35) decreased PC12 cell viability, but adenosine triphosphate-sensitive potassium channel activator diazoxide suppressed the decrease in PC12 cell viability induced by amyloid-β peptide (25-35). Diazoxide protected PC12 cells against amyloid-β peptide (25-35)-induced increases in mitochondrial membrane potential and intracellular reactive oxygen species levels. These protective effects were reversed by the selective mitochondrial adenosine triphosphate-sensitive potassium channel blocker 5-hydroxydecanoate. An inducible nitric oxide synthase inhibitor, Nw-nitro-L-arginine, also protected PC12 cells from amyloid-β peptide (25-35)-induced increases in both mitochondrial membrane potential and intracellular reactive oxygen species levels. However, the H202-degrading enzyme catalase could not reverse the amyloid-β peptide (25-35)-induced increase in intracellular reactive oxygen species. A 24-hour exposure to amyloid-13 peptide (25-35) did not result in apoptosis or necrosis, suggesting that the increases in both mitochondrial membrane potential and reactive oxygen species levels preceded cell death. The data suggest that amyloid-β peptide (25-35) cytotoxicity is associated with adenosine triphosphate-sensitive potassium channels and nitric oxide. Regulation of adenosine triphosphate-sensitive potassium channels suppresses PC12 cell cytotoxicity induced by amyloid-β peptide (25-35).
文摘This study was aimed to construct a biodegradable but reliable 3-β-hydroxybutymte biosensor. In this context a versatile paper based biosensor, quickly, easily and cheaply fabricated is reported. The procedure of fabrication is based on the assumption that the introduction of the enzyme in the carbon ink will allow enzyme stabilization and facilitate the study of the catalysis of enzymes and the detection of substrates. To prove this concept we use the enzyme 3-hydroxybutyrate dehydrogenase, in aqueous solution. This enzyme was chosen because it catalyzes the 3-β-hydroxybutyrate, which results from ketoacidosis. The quantification this substance in the diabetics' blood is very important as it can increase the reliability of the diagnosis of glycaemia. To prove the multi-use of this biosensor we not only study the redox process in steady state and during the catalytic process, but also detected and quantify the 3-β-hydroxybutyrate. Our results showed that it was possible to study the redox process that occurred during the catalysis and to confirm the amino acid residues that participate in it. It was also observed that glucose and ascorbic acid can interfere in the detection and quantification of the 3-β-hydroxybutyrate, what should be in mind when the quantification of the 3-β-hydroxybutyrate is made in blood samples.