The magnetic lens(Zumbro lens) is a critical part in proton radiography. Traditionally the matched beam for Zumbro lens in proton radiography is a virtual point source beam, which is not suitable for some cases, such ...The magnetic lens(Zumbro lens) is a critical part in proton radiography. Traditionally the matched beam for Zumbro lens in proton radiography is a virtual point source beam, which is not suitable for some cases, such as cylindrical samples. In these cases, a parallel beam is more appropriate. In this paper, a method, which uses quadrupole beamline, is proposed for designing a magnetic lens with parallel beam matched. Theoretical analysis is given. The results show that the matched beam for this lens is indeed parallel beam, while the major merits of Zumbro lens are inherited. Following this method, a theoretical design based on the 11-Me V cyclotron is presented.展开更多
Improvement of frame-rate is very important for high quality ultrasound imaging of fast-moving structures.It is also one of the key technologies of Three-Dimension(3-D) real-time medical imaging.In this paper,we have ...Improvement of frame-rate is very important for high quality ultrasound imaging of fast-moving structures.It is also one of the key technologies of Three-Dimension(3-D) real-time medical imaging.In this paper,we have demonstrated a beamforming method which gives imaging frame-rate increment without sacrificing the quality of medical images.By using wider and fewer transmit beams in combination with four narrower parallel receive beams,potentially increasing the imaging frame-rate by a factor four.Through employing full transmit aperture,controlling the mainlobe width,and suppressing sidelobes of angular responses,the inherent gain loss of normal parallel beamfomer can be compensated in the maximal degree.The noise and interference signals also can be suppressed effectively.Finally,we show comparable lateral resolution and contrast of ultrasound images to normal single widow weighting beamformer on simulated phantoms of point targets,cyst and fetus of 12th week.As the computational cost is linear with the number of array elements and the same with Delay And Sum(DAS) beamformers,this method has great ad-vantages of possibility for high frame-rate real-time applications.展开更多
In this paper, a new design of multi-parallel-beam (MPB) collimators with projection multiplexing is proposed. In the MPB system, two different oblique parallel channels are introduced in a conventional parallel-beam ...In this paper, a new design of multi-parallel-beam (MPB) collimators with projection multiplexing is proposed. In the MPB system, two different oblique parallel channels are introduced in a conventional parallel-beam collimator. The sensitivity of the single photon emission computed tomography (SPECT) system is improved by allowing projection overlapping. Comparative simulation studies were performed in the MPB collimators, general purpose parallel-beam (GPPB) collimators and high sensitivity parallel-beam (HSPB) collimators. In the simulation, attenuation, scattering and the impact of detector response were neglected. Simulation results show that the sensitivity is improved for the MPB collimator comparing with parallel-beam collimator. The behavior of spatial resolution is only different near the front face of the collimators and approaches that of the GPPB with increasing depth. Proper pre-filtering is helpful for the image reconstruction in the MPB collimators. Comparing with the HSPB collimator, the MPB can achieve a similar sensitivity and better resolution. The simulation ot the U87 cells, and their expression levels were higher in the 10 Gy group than in the 0 Gy group. The differential gene expression in DCX-U87 cells before and after radiation is helpful for future investigations into the mechanisms of radiation therapy in neurogliocytoma cells.展开更多
This paper firstly applies the finite impulse response filter （FIR） theory combined with the fast Fourier transform （FFT） method to generate two-dimensional Gaussian rough surface. Using the electric field integra...This paper firstly applies the finite impulse response filter （FIR） theory combined with the fast Fourier transform （FFT） method to generate two-dimensional Gaussian rough surface. Using the electric field integral equation （EFIE）, it introduces the method of moment （MOM） with RWG vector basis function and Galerkin＇s method to investigate the electromagnetic beam scattering by a two-dimensional PEC Gaussian rough surface on personal computer （PC） clusters. The details of the parallel conjugate gradient method （CGM） for solving the matrix equation are also presented and the numerical simulations are obtained through the message passing interface （MPI） platform on the PC clusters. It finds significantly that the parallel MOM supplies a novel technique for solving a two-dimensional rough surface electromagnetic-scattering problem. The influences of the root-mean-square height, the correlation length and the polarization on the beam scattering characteristics by two-dimensional PEC Gaussian rough surfaces are finally discussed.展开更多
Particle accelerators play an important role in a wide range of scientific discoveries and industrial applications. The self-consistent multi-particle simulation based on the particle-in-cell (PIC) method has been use...Particle accelerators play an important role in a wide range of scientific discoveries and industrial applications. The self-consistent multi-particle simulation based on the particle-in-cell (PIC) method has been used to study charged particle beam dynamics inside those accelerators. However, the PIC simulation is time-consuming and needs to use modern parallel computers for high-resolution applications. In this paper, we implemented a parallel beam dynamics PIC code on multi-node hybrid architecture computers with multiple Graphics Processing Units (GPUs). We used two methods to parallelize the PIC code on multiple GPUs and observed that the replication method is a better choice for moderate problem size and current computer hardware while the domain decomposition method might be a better choice for large problem size and more advanced computer hardware that allows direct communications among multiple GPUs. Using the multi-node hybrid architectures at Oak Ridge Leadership Computing Facility (OLCF), the optimized GPU PIC code achieves a reasonable parallel performance and scales up to 64 GPUs with 16 million particles.展开更多
We present the numerical and experimental study on the coherent beam combining of fibre amplifiers by means of simulated annealing （SA） algorithm. The feasibility is validated by the Monte Carlo simulation of correc...We present the numerical and experimental study on the coherent beam combining of fibre amplifiers by means of simulated annealing （SA） algorithm. The feasibility is validated by the Monte Carlo simulation of correcting static phase distortion using SA algorithm. The performance of SA algorithm under time-varying phase noise is numerically studied by dynamic simulation. It is revealed that the influence of phase noise on the performance of SA algorithm gets stronger with an increase in amplitude or frequency of phase noise; and the laser array that contains more lasers will be more affected from phase noise. The performance of SA algorithm for coherent beam combining is also compared with a widely used stochastic optimization algorithm, i.e., the stochastic parallel gradient descent （SPGD） algorithm. In a proof-of-concept experiment we demonstrate the coherent beam combining of two 1083~nm fibre amplifiers with a total output power of 12~W and 93% combining efficiency. The contrast of the far-field coherently combined beam profiles is calculated to be as high as 95%.展开更多
A novel scalable architecture for coherent beam combining with hybrid phase control involving passive phasing and active phasing in master oscillator-power amplifier configuration is presented. Wide-linewidth mutually...A novel scalable architecture for coherent beam combining with hybrid phase control involving passive phasing and active phasing in master oscillator-power amplifier configuration is presented. Wide-linewidth mutually injected passive phasing fibre laser arrays serve as master oscillators for the power amplifiers, and the active phasing using stochastic parallel gradient descent algorithm is induced. Wide-linewidth seed laser can suppress the stimulated Brillouin scattering effectively and improve the output power of the fibre laser amplifier, while hybrid phase control provides a robust way for in-phase mode coherent beam combining simultaneously. Experiment is performed by active phasing fibre laser amplifiers with passive phasing fibre ring laser array seed lasers. Power encircled in the main-lobe increases1.57 times and long-exposure fringe contrast is obtained to be 78% when the system evolves from passive phasing to hybrid phasing.展开更多
基金supported by National Natural Science Foundation of China(Nos.11475157,11405162,11205144 and 11176001)CAEP Developing Foundation(No.2014A0402016)+1 种基金CAEP President Foundation(No.201402086)CAEP Key Laboratory Foundation(No.PPL2013PZ09)
文摘The magnetic lens(Zumbro lens) is a critical part in proton radiography. Traditionally the matched beam for Zumbro lens in proton radiography is a virtual point source beam, which is not suitable for some cases, such as cylindrical samples. In these cases, a parallel beam is more appropriate. In this paper, a method, which uses quadrupole beamline, is proposed for designing a magnetic lens with parallel beam matched. Theoretical analysis is given. The results show that the matched beam for this lens is indeed parallel beam, while the major merits of Zumbro lens are inherited. Following this method, a theoretical design based on the 11-Me V cyclotron is presented.
文摘Improvement of frame-rate is very important for high quality ultrasound imaging of fast-moving structures.It is also one of the key technologies of Three-Dimension(3-D) real-time medical imaging.In this paper,we have demonstrated a beamforming method which gives imaging frame-rate increment without sacrificing the quality of medical images.By using wider and fewer transmit beams in combination with four narrower parallel receive beams,potentially increasing the imaging frame-rate by a factor four.Through employing full transmit aperture,controlling the mainlobe width,and suppressing sidelobes of angular responses,the inherent gain loss of normal parallel beamfomer can be compensated in the maximal degree.The noise and interference signals also can be suppressed effectively.Finally,we show comparable lateral resolution and contrast of ultrasound images to normal single widow weighting beamformer on simulated phantoms of point targets,cyst and fetus of 12th week.As the computational cost is linear with the number of array elements and the same with Delay And Sum(DAS) beamformers,this method has great ad-vantages of possibility for high frame-rate real-time applications.
基金Supported by the Priority Academic Program Development of Jiangsu College Education
文摘In this paper, a new design of multi-parallel-beam (MPB) collimators with projection multiplexing is proposed. In the MPB system, two different oblique parallel channels are introduced in a conventional parallel-beam collimator. The sensitivity of the single photon emission computed tomography (SPECT) system is improved by allowing projection overlapping. Comparative simulation studies were performed in the MPB collimators, general purpose parallel-beam (GPPB) collimators and high sensitivity parallel-beam (HSPB) collimators. In the simulation, attenuation, scattering and the impact of detector response were neglected. Simulation results show that the sensitivity is improved for the MPB collimator comparing with parallel-beam collimator. The behavior of spatial resolution is only different near the front face of the collimators and approaches that of the GPPB with increasing depth. Proper pre-filtering is helpful for the image reconstruction in the MPB collimators. Comparing with the HSPB collimator, the MPB can achieve a similar sensitivity and better resolution. The simulation ot the U87 cells, and their expression levels were higher in the 10 Gy group than in the 0 Gy group. The differential gene expression in DCX-U87 cells before and after radiation is helpful for future investigations into the mechanisms of radiation therapy in neurogliocytoma cells.
基金supported by the National Natural Science Foundation of China (Grant No 60571058)the Specialized Research Fund for the Doctoral Program of Higher Education,China (Grant No 20070701010)
文摘This paper firstly applies the finite impulse response filter （FIR） theory combined with the fast Fourier transform （FFT） method to generate two-dimensional Gaussian rough surface. Using the electric field integral equation （EFIE）, it introduces the method of moment （MOM） with RWG vector basis function and Galerkin＇s method to investigate the electromagnetic beam scattering by a two-dimensional PEC Gaussian rough surface on personal computer （PC） clusters. The details of the parallel conjugate gradient method （CGM） for solving the matrix equation are also presented and the numerical simulations are obtained through the message passing interface （MPI） platform on the PC clusters. It finds significantly that the parallel MOM supplies a novel technique for solving a two-dimensional rough surface electromagnetic-scattering problem. The influences of the root-mean-square height, the correlation length and the polarization on the beam scattering characteristics by two-dimensional PEC Gaussian rough surfaces are finally discussed.
文摘Particle accelerators play an important role in a wide range of scientific discoveries and industrial applications. The self-consistent multi-particle simulation based on the particle-in-cell (PIC) method has been used to study charged particle beam dynamics inside those accelerators. However, the PIC simulation is time-consuming and needs to use modern parallel computers for high-resolution applications. In this paper, we implemented a parallel beam dynamics PIC code on multi-node hybrid architecture computers with multiple Graphics Processing Units (GPUs). We used two methods to parallelize the PIC code on multiple GPUs and observed that the replication method is a better choice for moderate problem size and current computer hardware while the domain decomposition method might be a better choice for large problem size and more advanced computer hardware that allows direct communications among multiple GPUs. Using the multi-node hybrid architectures at Oak Ridge Leadership Computing Facility (OLCF), the optimized GPU PIC code achieves a reasonable parallel performance and scales up to 64 GPUs with 16 million particles.
文摘We present the numerical and experimental study on the coherent beam combining of fibre amplifiers by means of simulated annealing （SA） algorithm. The feasibility is validated by the Monte Carlo simulation of correcting static phase distortion using SA algorithm. The performance of SA algorithm under time-varying phase noise is numerically studied by dynamic simulation. It is revealed that the influence of phase noise on the performance of SA algorithm gets stronger with an increase in amplitude or frequency of phase noise; and the laser array that contains more lasers will be more affected from phase noise. The performance of SA algorithm for coherent beam combining is also compared with a widely used stochastic optimization algorithm, i.e., the stochastic parallel gradient descent （SPGD） algorithm. In a proof-of-concept experiment we demonstrate the coherent beam combining of two 1083~nm fibre amplifiers with a total output power of 12~W and 93% combining efficiency. The contrast of the far-field coherently combined beam profiles is calculated to be as high as 95%.
基金supported by the Innovation Foundation for Graduates in National University of Defense Technology,China (GrantNo.B080702)
文摘A novel scalable architecture for coherent beam combining with hybrid phase control involving passive phasing and active phasing in master oscillator-power amplifier configuration is presented. Wide-linewidth mutually injected passive phasing fibre laser arrays serve as master oscillators for the power amplifiers, and the active phasing using stochastic parallel gradient descent algorithm is induced. Wide-linewidth seed laser can suppress the stimulated Brillouin scattering effectively and improve the output power of the fibre laser amplifier, while hybrid phase control provides a robust way for in-phase mode coherent beam combining simultaneously. Experiment is performed by active phasing fibre laser amplifiers with passive phasing fibre ring laser array seed lasers. Power encircled in the main-lobe increases1.57 times and long-exposure fringe contrast is obtained to be 78% when the system evolves from passive phasing to hybrid phasing.
