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Somnambulism: Varenicline-Induced Sleep Driving
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作者 Samer Alkhuja Monika Girgis +2 位作者 Mohammad Ali Pravinkumar Patel Olutunde Odeyemi 《Case Reports in Clinical Medicine》 2023年第7期213-217,共5页
Background: Varenicline, which is derived from the cytisine compound, is used to assess in smoking cessation. Sleep driving (SD) is often classified as a variant of somnambulism. Although, somnambulism has been report... Background: Varenicline, which is derived from the cytisine compound, is used to assess in smoking cessation. Sleep driving (SD) is often classified as a variant of somnambulism. Although, somnambulism has been reported as a side effect of varenicline, varenicline-induced sleep driving (VISD) has not been reported. Case Report: A 56-year-old man with a history of 35 pack year smoking who presented for smoking cessation counseling. Treatment with varenicline was initiated. In the following night, the patient drove to a shopping center and woke up in his car. Varenicline was discontinued. SD has not been reported in the following nights. In a repeated attempt to stop smoking, treatment with varenicline was resumed by the patient. SD reoccurred in the following night. Varenicline was discontinued indefinitely, and SD has not been reported. 展开更多
关键词 VARENICLINE Sleep Walking Arousal Parasomnia
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Sleep disorders and chronic kidney disease 被引量:18
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作者 Stephanie C Maung Ammar El Sara +2 位作者 Cherylle Chapman Danielle Cohen Daniel Cukor 《World Journal of Nephrology》 2016年第3期224-232,共9页
Sleep disorders have a profound and well-documented impact on overall health and quality of life in the general population. In patients with chronic disease, sleep disorders are more prevalent, with an additional morb... Sleep disorders have a profound and well-documented impact on overall health and quality of life in the general population. In patients with chronic disease, sleep disorders are more prevalent, with an additional morbidity and mortality burden. The complex and dynamic relationship between sleep disorders and chronic kidney disease(CKD) remain relatively little investigated. This article presents an overview of sleep disorders in patients with CKD, with emphasis on relevant pathophysiologic underpinnings and clinical presentations. Evidence-based interventions will be discussed, in the context of individual sleep disorders, namely sleep apnea, insomnia, restless leg syndrome and excessive daytime sleepiness. Limitations of the current knowledge as well as future research directions will be highlighted, with a final discussion of different conceptual frameworks of the relationship between sleep disorders and CKD. 展开更多
关键词 Chronic kidney disease End-stage renal disease Renal replacement therapy HEMODIALYSIS Kidney transplantation Sleep initiation and maintenance disorders Disorders of excessive somnolence Intrinsic sleep disorders parasomnias Restless legs syndrome Sleep apnea DYSSOMNIAS Circadian rhythm disorders MELATONIN
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Childhood epilepsy and sleep 被引量:8
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作者 Mohammed A Al-Biltagi 《World Journal of Clinical Pediatrics》 2014年第3期45-53,共9页
Sleep and epilepsy are two well recognized conditions that interact with each other in a complex bi-directional way. Some types of epilepsies have increased activity during sleep disturbing it; while sleep deprivation... Sleep and epilepsy are two well recognized conditions that interact with each other in a complex bi-directional way. Some types of epilepsies have increased activity during sleep disturbing it; while sleep deprivation aggravates epilepsy due to decreased seizure threshold. Epilepsy can deteriorate the sleep-related disorders and at the same time; the parasomnias can worsen the epilepsy. The secretion of sleep-related hormones can also be affected by the occurrence of seizures and supplementation of epileptic patients with some of these sleep-related hormones may have a beneficial role in controlling epilepsy. 展开更多
关键词 NOCTURNAL FRONTAL LOBE epilepsy SLEEP parasomnias Sleep-related HORMONES
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Case report: Desmopressin and somnambulism
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作者 Charlotte Van Herzeele Karlien Dhondt Johan Vande Walle 《Open Journal of Pediatrics》 2013年第3期208-210,共3页
Background: Nocturnal enuresis is caused by a mismatch between nocturnal urine production and bladder capacity. Together with a presumed decreased arousability, this results in an inability to awaken in response to a ... Background: Nocturnal enuresis is caused by a mismatch between nocturnal urine production and bladder capacity. Together with a presumed decreased arousability, this results in an inability to awaken in response to a full bladder. According to recent findings, a disrupted sleep might play a role in the pathophysiology of enuresis. Case: A 7-year-old boy was diagnosed with primary nocturnal enuresis caused by nocturnal polyuria and a concomitant parasomnia, somnambulism. A polysomnographic study was performed before treating the nocturnal enuresis with the oral lyophylisate formulation of desmopressin (melt). After 1 day of treatment, both nocturnal enuresis and somnambulism disappeared. Treatment was ceased after six months. One week later, the child started to produce more urine and redeveloped nocturnal polyuria. Somnambulism reappeared followed by nocturnal enuresis two weeks later. The same treatment protocol was started up, resulting in disappearance of both nocturnal enuresis and somnambulism. Conclusion: This case report documents the beneficial effect of desmopressin melt on both nocturnal enuresis, caused by nocturnal polyuria, and a concomitant parasomnia in particularly somnambulism. 展开更多
关键词 Children ENURESIS BEDWETTING SOMNAMBULISM Sleep SLEEPWALKING DESMOPRESSIN Nocturnal POLYURIA Parasomnia
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