[ Objective] This study aimed to investigate pathological changes in various organs of piglets infected with classical swine fever and provide reliable basis for accurate diagnosis of classical swine fever. [ Method] ...[ Objective] This study aimed to investigate pathological changes in various organs of piglets infected with classical swine fever and provide reliable basis for accurate diagnosis of classical swine fever. [ Method] By using paraffin embedding, section slicing and HE staining, histopathological changes in the heart, liver, spleen, lung, kidney and small intestine tissues of five diseased piglets were observed. C Result] Classical swine fever virus could lead to multiple visceral and mueosal hemorrhages, inflammatory cell infiltration, necrosis and other pathological changes. [ Conclusion ] Classical swine fever virus can further cause progressive degeneration and necrosis of different cells, resulting in immune injury.展开更多
基金Supported by Project of Agricultural Science and Technology Achievement Transformation of the Ministry of Science and Technology of China(2012GB2A200045)Major Project for Cultivation of New Varieties of Genetically Modified Organisms of the Ministry of Agriculture(2011ZX08006001)Science and Technology Development Project of Qinghuangdao City(NO.201101A181)
文摘[ Objective] This study aimed to investigate pathological changes in various organs of piglets infected with classical swine fever and provide reliable basis for accurate diagnosis of classical swine fever. [ Method] By using paraffin embedding, section slicing and HE staining, histopathological changes in the heart, liver, spleen, lung, kidney and small intestine tissues of five diseased piglets were observed. C Result] Classical swine fever virus could lead to multiple visceral and mueosal hemorrhages, inflammatory cell infiltration, necrosis and other pathological changes. [ Conclusion ] Classical swine fever virus can further cause progressive degeneration and necrosis of different cells, resulting in immune injury.