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Diagnosis and surgical treatment of hepatic hilar cholangiocarcinoma 被引量:3
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作者 Yang, Wei-Liang Zhang, Xin-Chen +1 位作者 Zhang, Dong-Wei Tong, Bai-Feng 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS 2007年第6期631-635,共5页
BACKGROUND: Hepatic hilar cholangiocarcinoma can be diagnosed early with the progress in diagnostic imaging, and thus the rate of resection of the tumor has increased markedly. To assess the effectiveness of resection... BACKGROUND: Hepatic hilar cholangiocarcinoma can be diagnosed early with the progress in diagnostic imaging, and thus the rate of resection of the tumor has increased markedly. To assess the effectiveness of resection, we reviewed 185 cases of hepatic hilar cholangiocarcinoma diagnosed and treated at our hospital. METHODS: The clinical data of 185 patients with hepatic hilar cholangiocarcinoma who had been treated surgically from 1972 to 2006 were retrospectively analyzed. RESULTS: The records of the 185 patients were divided into first stage (1972-1986) or second stage (1987-2006) according to the incidence of the tumor and its resection rate. Primary symptoms included upper abdominal discomfort or pain, anorexia, tiredness, weight loss and progressive jaundice. Ultrasonography, computed tomography (CT), magnetic resonance imaging (MRI), and magnetic resonance cholangiopancreatography (MRCP) were first line methods for atraumatic diagnosis. If the patients displayed intrahepatic bile duct dilatation or were diagnosed as suffering from extrahepatic obstructive jaundice, percutaneous transhepatic cholangiography (PTC), MRCP or endoscopic retrograde cholangiopancreatography (ERCP) should be used. In this series, 87 patients underwent resection of the tumor (47.0%). Of the 87 patients, 43 received radical resection and 44 palliative resection. Fifteen patients underwent resection in the first stage and 72 in the second stage. A total of 74 patients were followed up after the resection. The median survival time of the radical resection group was 37 months and that of the palliative resection group was 17 months (P<0.001). The other 62 patients receiving no resection died within 1.5 years. CONCLUSIONS: Once patients are diagnosed with hepatic hilar cholangiocarcinoma, they should undergo exploratory laparotomy. Resection is the most effective method for the treatment of hepatic hilar cholangiocarcinoma. 展开更多
关键词 bile duct neoplasms hepatic hilar cholangiocarcinoma diagnosis surgical treatment
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Diagnosis and surgical treatment of intraveneous leiomyomatosis extending into the heart:two cases report and review of the literature 被引量:5
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作者 Xiaowei Wang Lin Zhang Yijiang Chen Shijiang Zhang Jianwei Qin Yanhu Wu Jinhua Luo 《Journal of Nanjing Medical University》 2009年第5期305-310,共6页
Objective: To investigate the clinical characteristics, diagnosis and surgical treatment of intravenous leiomyomatosis (IVL), and outline the differences between Chinese and overseas cases. Methods: Clinical data ... Objective: To investigate the clinical characteristics, diagnosis and surgical treatment of intravenous leiomyomatosis (IVL), and outline the differences between Chinese and overseas cases. Methods: Clinical data of two IVL cases, treated in our hospital, were analyzed retrospectively and the related literature was also reviewed. The data of preoperative diagnostic rate, surgical procedures, and postoperative recurrence between patients in China and other countries were compared. Results: The first stage operation was performed successfully in 2 patients. However, they refused subsequent therapies, including a second stage operation to excise the remnants Of the tumor, uterus, bilateral oviducts and ovaries, and anti-estrogen therapy. Both suffered from IVL recurrence, one at 6-month and the other at 9-month, and died at 16-month and 12-month respectively after the first stage surgery. Worldwide reports of 110 IVL cases were reviewed, which included 28 cases in China and 82 cases in other countries. In the majority of the Chinese patients, tumors only extended into the fight atrium rather than the right ventricle (RA 22 cases vs RV 4 cases). However, among the overseas patients, the rate of extension into the right atrium was similar to that of extension into the right ventricle (RA 41 cases vs RV 38 cases). The rate of hysterectomies was not significantly different between Chinese and overseas patients ( 67.86% vs 55.9%, P=0.278). The rate of correct preoperative diagnosis in the Chinese patients was significantly lower than that in the overseas patients (32.14% vs 80%, P=0.000002.), as well asthe rate of complete excision of the tumor (22.7@0 vs 75.5%, P=0.000001). The proportion of patients who undergoing a single-stage or a two-stage operation was similar in Chinese and overseas patients. The recurrence rate was significantly higher in the Chinese patients than in the overseas patients (36.8% vs 9.1%, P=0.0055), and the patients with tumor recurrence were partial tumor excision patients. Conclusion: The possibility of IVL should be considered if echocardiography in female patients demonstrates a tumor in the right heart and a mass in the inferior vena cava (IVC). Further imaging should be performed to confirm the diagnosis. The correct diagnosis and accurate preoperative delineation of tumor extension are essential for an optimal surgical outcome. The key point in IVL treatment is the complete excision of tumors (single-stage or two-stage surgical procedure). 展开更多
关键词 Intravenous leiomyomatosis (IVL) HEART diagnosis surgical treatment
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Colorectal cancer in geriatric patients: Endoscopic diagnosis and surgical treatment 被引量:1
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作者 Andreas Kirchgatterer Pius Steiner +6 位作者 Dietmar Hubner Eva Fritz Gerhard Aschl Josef Preisinger Maximilian Hinterreiter Bernhard Stadler Peter Knoflach 《World Journal of Gastroenterology》 SCIE CAS CSCD 2005年第3期315-318,共4页
AIM: To investigate the prevalence of colorectal cancer in geriatrie patients undergoing endoscopy and to analyze their outcome. METHODS: All consecutive patients older than 80 years who underwent lower gastrointestin... AIM: To investigate the prevalence of colorectal cancer in geriatrie patients undergoing endoscopy and to analyze their outcome. METHODS: All consecutive patients older than 80 years who underwent lower gastrointestinal endoscopy between January 1995 and December 2002 at our institution were included. patients with endoscopic diagnosis of colorectal cancer were evaluated with respect to indication, localization and stage of cancer, therapeutic consequences, and survival. RESULTS: Colorectal cancer was diagnosed in 88 patients (6% of all endoscopies, 55 women and 33 men, mean age 85.2 years). Frequent indications were lower gastrointestinal bleeding (25%), anemia (24%) or sonographic suspicion of tumor (10%). Localization of cancer was predominantly the sigmoid colon (27%), the rectum (26%), and the ascending colon (20%). Stage Dukes A was rare (1%), but Dukes D was diagnosed in 22% of cases. Curative surgery was performed in 54 patients (61.4%), in the remaining 34 patients (38.6%) surgical treatment was not feasible due to malnutrition and asthenia or cardiopulmonary comorbidity (15 patients), distant metastases (11 patients) or refusal of operation (8 patients). patients undergoing surgery had a very low in-hospital mortality rate (2%). Operated patients had a one-year and three-year survival rate of 88% and 49%, and the survival rates for non-operated patients amounted to 46% and 13% respectively. CONCLUSION: Nearly two-thirds of 88 geriatrie patiente with endoscopic diagnosis of colorectal cancer underwent successful surgery at a very low perioperative mortality rate, resulting in significantly higher survival rates. Hence, the clinical relevance of lower gastrointestinal endoscopy and oncologic surgery in geriatrie patients is demonstrated. 展开更多
关键词 Colorectal cancer Endoscopic diagnosis surgical treatment
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Diagnosis and Treatment of Cholangiocarcinoma: A Consensus from Surgical Specialists of China 被引量:2
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作者 Jian-qiang Cai Shou-wang Cai +50 位作者 Wen-ming Cong Min-shan Chen Ping Chen Xiao-ping Chen Yan-ling Chen Yi-fa Chen Chao-liu Dai Qiang Huang Zhi-yong Huang Bo Jiang Bin Jiang Ke-wei Jiang Bo Li Zong-fangLi Li-jian Liang Bin Liu Hui-chun Liu Lian-xin Liu Qing-guang Liu Rong Liu Ying-bin Liu Jian-guo Lu Shi-chun Lu Yi Lu Yi-lei Mao Bin Mei Jun Niu Bao-gang Peng Xiao Qin Yu-dong Qiu Guang-yi Wang Yao-don Wangg Zhi-ming Wang Ren-hua Wan Ya-fu Wu Bao-cai Xing Feng Xia Ge-liang Xu Jia-mei Yang Xiao-fang Yu Yong Zeng Yong-yi Zeng Bi-xiang Zhang Bin-hao Zhang Qi-yu Zhang Shui-jun Zhang Wan-guang Zhang Yong-jie Zhang Zhi-wei Zhang Dong Zhou Wei-ping Zhou 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2014年第4期469-475,共7页
Cholangiocarcinoma refers to malignant tumors that develop in epithelial lining of biliary system, and it is divided into two categories according to tumor location, intrahepatic cholangiocarcinoma (ICC) and extrahe... Cholangiocarcinoma refers to malignant tumors that develop in epithelial lining of biliary system, and it is divided into two categories according to tumor location, intrahepatic cholangiocarcinoma (ICC) and extrahepatic cholangiocarcinoma (ECC). ICC occurs from the epithelial cells of the intrahepatic bile duct, its branches and interlobular biliary tree; and ECC is divided into hilar cholangiocarcinoma and distal cholangiocarcinoma by the circumscription at the confluence of cystic duct and the common hepatic duct. 展开更多
关键词 A Consensus from surgical Specialists of China diagnosis and treatment of Cholangiocarcinoma
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DIAGNOSIS AND SURGICAL TREATMENT OF 103 PATIENTS WITH EARLY ESOPHAGEAL CANCER AND CARDIAC CANCER OF STOMACH
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作者 吴昌荣 张振斌 +2 位作者 朱宗海 秦德兴 王国清 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 1994年第4期305-308,共4页
Screening of the general population for esophageal cancer and gastric cardia cancer using an occult blood bead detector supplemented by fiberogastroscopy was able to detect 103 cases with early esophageal cancer and g... Screening of the general population for esophageal cancer and gastric cardia cancer using an occult blood bead detector supplemented by fiberogastroscopy was able to detect 103 cases with early esophageal cancer and gastric cardia cancer at Yangzhong County where the incidence was high from Apr. 1986 to Feb. 1992. Among them, there were 47 cancers of esophagus and 56 cancers of gastric cardia through pathological verification.. They took 17.1% (103/604) of the correspouding esophageal and gastric cardia caucers. We thought that about 90% of early esophageal and gastric cardia cancers have symptoms. We should couduct screening for high risk group in the area where the incidence is high at regular intervals. Besides, it is also important to strengthen propaganda for cancer prevention and self-protection for population, to emphasize the diagnosis and recognition of early cancer for medical workers. 展开更多
关键词 Esophagus tumour Stomach tumour Early diagnosis Screening surgical treatment Gastroscopy.
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Diagnosis and one stage surgical treatment of lower thoracic ossification of ligamentum flavum combined with lumbar spinal stenosis
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作者 王哲 《外科研究与新技术》 2011年第2期95-96,共2页
Objective To study the diagnosis and treatment of lower thoracic ossification of ligamentum flavum(OLF) combined with lumbar spinal stenosis.Methods Retrospective analysis was carried out on 11 cases of lower thoracic... Objective To study the diagnosis and treatment of lower thoracic ossification of ligamentum flavum(OLF) combined with lumbar spinal stenosis.Methods Retrospective analysis was carried out on 11 cases of lower thoracic OLF combined with 展开更多
关键词 ODI OLF diagnosis and one stage surgical treatment of lower thoracic ossification of ligamentum flavum combined with lumbar spinal stenosis
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Surgical treatment of mixed cervical spondylosis with spontaneous cerebrospinal fluid leakage: A case report 被引量:1
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作者 Zhong Yu Hao-Fu-Zi Zhang Yan-Jun Wang 《World Journal of Clinical Cases》 SCIE 2023年第29期7242-7247,共6页
BACKGROUND Spontaneous cerebrospinal fluid(CSF)leaks associated with cervical spondylosis are rare.To our knowledge,only a few cases have been reported in which treatment is challenging and varies from case to case.He... BACKGROUND Spontaneous cerebrospinal fluid(CSF)leaks associated with cervical spondylosis are rare.To our knowledge,only a few cases have been reported in which treatment is challenging and varies from case to case.Here,we review the literature and describe the surgical treatment of a 70-year-old woman who presented with a CSF leak due to a cervical spine spur.CASE SUMMARY A 70-year-old female patient who was treated for a cerebral infarction,presented with complains of weakness in the right lower extremity and a feeling of stepping on cotton.The patient underwent regular neck massage and presented with neck and right shoulder pain radiating to the right upper extremity one-month ago.Magnetic resonance imaging showed a strip of leaking cerebrospinal fluid posterior to the C1-4 vertebrae,and computed tomography showed a“sickleshaped”disc prolapse with calcification in C4/5.We chose to perform an anterior cervical discectomy.When the prolapsed C4/5 disc was scraped,clear fluid leakage was observed,and exploration revealed a 1 mm diameter rupture in the anterior aspect of the dura mater,which was compressed continuously with cotton patties,with no significant cerebrospinal fluid leakage after 1 h.CONCLUSION Three months after surgery,the patient was asymptomatic and follow-up imaging demonstrated complete resolution. 展开更多
关键词 Cerebrospinal fluid leak Degenerative spine pathology Cervical spine surgical treatment Case report
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Impact of HLA-G analysis in prevention, diagnosis and treatment of pathological conditions 被引量:3
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作者 Daria Bortolotti Valentina Gentili +3 位作者 Antonella Rotola Enzo Cassai Roberta Rizzo Dario Di Luca 《World Journal of Methodology》 2014年第1期11-25,共15页
Human leukocyte antigen-G(HLA-G) is a non-classical HLA class Ⅰ molecule that differs from classical HLA class Ⅰ molecules by low polymorphism and tissue distribution. HLA-G is a tolerogenic molecule with an immune-... Human leukocyte antigen-G(HLA-G) is a non-classical HLA class Ⅰ molecule that differs from classical HLA class Ⅰ molecules by low polymorphism and tissue distribution. HLA-G is a tolerogenic molecule with an immune-modulatory and anti-inflammatory function on both innate and adaptative immunity. This peculiar characteristic of HLA-G has led to investigations of its role in pathological conditions in order to define possible uses in diagnosis, prevention and treatment. In recent years, HLA-G has been shown to have an important implication in different inflammatory and autoimmune diseases, pregnancy complications, tumor development and aggressiveness, and susceptibility to viral infections. In fact, HLA-G molecules have been reported to alternate at both genetic and protein level in different disease situations, supporting its crucial role in pathological conditions. Specific pathologies show altered levels of soluble(s)HLA-G and different HLA-G gene polymorphisms seem to correlate with disease. This review aims to update scientific knowledge on the contribution of HLA-G in managing pathological conditions. 展开更多
关键词 Human LEUKOCYTE antigen-G pathology PROGNOSIS diagnosis treatment MARKER
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DIAGNOSIS AND SURGICAL MANAGEMENT FOR RETROSTERNAL THYROID MASS
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作者 崔玉尚 张志庸 +3 位作者 李单青 李力 张恒 李泽坚 《Chinese Medical Sciences Journal》 CAS CSCD 2002年第3期173-177,共5页
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关键词 retrosternal goiter thyroid carcinoma diagnosis surgeryObjective. To understand the clinical manifestations diagnostic methods surgical management and prognosis of retrosternal thyroid masses in various pathological types. Methods. Sixty
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Surgical treatment of 1360 cases of Budd-Chiari syndrome: 20-year experience 被引量:9
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《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS 2004年第3期391-394,共4页
关键词 BUDD-CHIARI SYNDROME diagnosis surgical treatment
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Gallbladder neuroendocrine carcinoma diagnosis, treatment and prognosis based on the SEER database: A literature review 被引量:1
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作者 Xing-Chen Cai Sheng-Dong Wu 《World Journal of Clinical Cases》 SCIE 2022年第23期8212-8223,共12页
BACKGROUND Gallbladder neuroendocrine carcinoma(GB-NEC)has a low incidence rate;therefore,its clinical characteristics,diagnosis,treatment and prognosis are not well explored.AIM To review recent research and analyze ... BACKGROUND Gallbladder neuroendocrine carcinoma(GB-NEC)has a low incidence rate;therefore,its clinical characteristics,diagnosis,treatment and prognosis are not well explored.AIM To review recent research and analyze corresponding data in the Surveillance Epidemiology and End Results(SEER)database.METHODS Data of GB-NEC(n=287)and gallbladder adenocarcinoma(GB-ADC)(n=19484)patients from 1975 to 2016 were extracted from the SEER database.Survival analysis was performed using Kaplan–Meier and Cox proportional hazards regression.P<0.05 was considered statistically significant.We also reviewed 108 studies retrieved from PubMed and Reference Citation Analysis(https://www.referencecitationanalysis.com/).The keywords used for the search were:"(Carcinoma,Neuroendocrine)AND(Gallbladder Neoplasms)".RESULTS The GB-NEC incidence rate was 1.6%(of all gallbladder carcinomas),male to female ratio was 1:2 and the median survival time was 7 mo.The 1-,2-,3-and 5-year overall survival(OS)was 36.6%,17.8%,13.2%and 7.3%respectively.Serum chromogranin A levels may be a specific tumor marker for the diagnosis of GBNEC.Elevated carcinoembryonic antigen,carbohydrate antigen(CA)-19-9 and CA-125 levels were associated with poor prognosis.Age[hazard ratio(HR)=1.027,95%confidence interval(CI):1.006–1.047,P=0.01]and liver metastasis(HR=3.055,95%CI:1.839–5.075,P<0.001)are independent prognostic risk factors for OS.Patients with advanced GB-NEC treated with surgical resection combined with radiotherapy and/or chemotherapy may have a better prognosis than those treated with surgical resection alone.There was no significant difference in OS between GB-NEC and GB-ADC.CONCLUSION The clinical manifestations and prognosis of GB-NEC are similar to GB-ADC,but the treatment is completely different.Early diagnosis and treatment are the top priorities. 展开更多
关键词 Clinical features diagnosis Gallbladder neuroendocrine tumor pathology treatment
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Interpretation of Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia(Trial Version 7) 被引量:1
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作者 Jinfeng CHEN Zhongyi LEI +6 位作者 Chaofeng LIU Hong FAN Peng LEI Xueping WU Xiaoyong YU Yanfen ZHOU Jiejun HOU 《Medicinal Plant》 CAS 2020年第3期78-83,共6页
On March 3,2020,the National Health Commission and the National Administration of Traditional Chinese Medicine of China jointly promulgated the Notice on Printing and Distributing the Diagnosis and Treatment Protocol ... On March 3,2020,the National Health Commission and the National Administration of Traditional Chinese Medicine of China jointly promulgated the Notice on Printing and Distributing the Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia(Trial Version 7).The content has been revised and supplemented on the basis of the Version 6,including etiological characteristics and pathological changes in lung,heart,kidney,spleen,liver,gallbladder,esophagus,stomach and intestinal mucosal epithelium.In particular,the diagnosis and treatment methods of traditional Chinese medicine are supplemented.It provides an evidence-based diagnosis and treatment protocol for the treatment and recovery of suspected and confirmed cases of novel coronavirus pneumonia with traditional Chinese medicine and Western medicine. 展开更多
关键词 Novel coronavirus pneumonia diagnosis and treatment protocol Version 7 Traditional Chinese medicine pathological change
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DIAGNOSIS AND TREATMENT OF PRIMARY URETERAL CARCINOMA-A REPORT OF 15 CASES
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作者 陆灿辉 谢克基 +1 位作者 张甘雄 谢文琪 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 1996年第2期144-147,共4页
Fifteen cases with primary ureteral carcinomas are reported with a review of the literature. We concludeL Excretory urography is the main metbod of diagnosis;retrograde uretero-pyelography is more helpful in diagnosis... Fifteen cases with primary ureteral carcinomas are reported with a review of the literature. We concludeL Excretory urography is the main metbod of diagnosis;retrograde uretero-pyelography is more helpful in diagnosis; cystoscopy is also netessary before operation;CT is useful in diagnosing and staging; ureteroscopy could be performed if necessary; the traditional total nephroureterectomy witb a cuff excision of the urinary bladder remains the basic treatment of choice; cystoscopy,excretory urography and adjuvant intravesical therapy should he carried out regularly after operation. 展开更多
关键词 Ureteral carcinoma diagnosis surgical treatment
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REFLECTIONS ON SURGICAL TREATMENT OF 214 CASES OF PRIMARY MEDIASTINAL TUMOR
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作者 梁景仁 陈健 +1 位作者 贺定超 鲁舒林 《Journal of Pharmaceutical Analysis》 CAS 1997年第1期70-73,共4页
Our hospital documented 214 cases of primary mediastinal tumor from May 1957 to July 1995. They were treated surgically, There were 184 benign cases (85. 98% ), and 30 malignant cases (14.02 % ). Among them, there wer... Our hospital documented 214 cases of primary mediastinal tumor from May 1957 to July 1995. They were treated surgically, There were 184 benign cases (85. 98% ), and 30 malignant cases (14.02 % ). Among them, there were 63 cases of neurogenic tumor (29.43 % ), 48 cases of thymic tumor (22. 4% ), 41 cases of teratoid tumor (19. 16% ), 12 cases of bronchial cyst (5. 61% ), and 9cases of intrathoracic adenoma of thyroid (4. 21%). The authors mainiy discuss the early diagnosis,tumor variety, operating incisions, and operating essentials. 展开更多
关键词 mediastinal tumor surgical treatment diagnosis
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Diagnosis and treatment of mixed glioma
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作者 章翔 易声禹 +4 位作者 李安民 张志文 张剑宁 付相平 黄高升 《Journal of Medical Colleges of PLA(China)》 CAS 1995年第2期152-156,共5页
The authors present 83 patients with mixed glioma with experiences in clinical diagnosis and treatment.In all these cases.there were 44 tumors as grade 1 or 2,and 39 as grade 3 or 4.In 39 tumors.two glial components(o... The authors present 83 patients with mixed glioma with experiences in clinical diagnosis and treatment.In all these cases.there were 44 tumors as grade 1 or 2,and 39 as grade 3 or 4.In 39 tumors.two glial components(oligodendrocytes and astrocytes) occurr 展开更多
关键词 BRAIN TUMOR MIXED GLIOMA diagnosis:surgical treatment
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Adhesive small bowel adhesions obstruction: Evolutions in diagnosis, management and prevention 被引量:29
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作者 Fausto Catena Salomone Di Saverio +4 位作者 Federico Coccolini Luca Ansaloni Belinda De Simone Massimo Sartelli Harry Van Goor 《World Journal of Gastrointestinal Surgery》 SCIE CAS 2016年第3期222-231,共10页
Intra-abdominal adhesions following abdominal surgery represent a major unsolved problem. They are the first cause of small bowel obstruction. Diagnosis is based on clinical evaluation, water-soluble contrast followth... Intra-abdominal adhesions following abdominal surgery represent a major unsolved problem. They are the first cause of small bowel obstruction. Diagnosis is based on clinical evaluation, water-soluble contrast followthrough and computed tomography scan. For patients presenting no signs of strangulation, peritonitis or severe intestinal impairment there is good evidence to support non-operative management. Open surgery is the preferred method for the surgical treatment of adhesive small bowel obstruction, in case of suspected strangulation or after failed conservative management, but laparoscopy is gaining widespread acceptance especially in selected group of patients. "Good" surgical technique and anti-adhesive barriers are the main current concepts of adhesion prevention. We discuss current knowledge in modern diagnosis and evolving strategies for management and prevention that are leading to stratified care for patients. 展开更多
关键词 ADHESIVE DISEASE Intestinal OBSTRUCTION diagnosis of ADHESIVE small bowel OBSTRUCTION NONOPERATIVE MANAGEMENT of ADHESIVE DISEASE Emergency surgical treatment
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Surgically treated primary malignant tumor of small bowel:A clinical analysis 被引量:12
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作者 Han, Shao-Liang Cheng, Jun +3 位作者 Zhou, Hong-Zhong Guo, Sheng-Cong Jia, Zeng-Rong Wang, Peng-Fei 《World Journal of Gastroenterology》 SCIE CAS CSCD 2010年第12期1527-1532,共6页
AIM:To evaluate the clinical presentation,treatment and survival of patients with primary malignant tumor of small bowel(PMTSB).METHODS:Clinicopathologic data about 141 surgically treated PMTSB patients(91 males and 5... AIM:To evaluate the clinical presentation,treatment and survival of patients with primary malignant tumor of small bowel(PMTSB).METHODS:Clinicopathologic data about 141 surgically treated PMTSB patients(91 males and 50 females) at the median age of 53.5 years(range 23-79 years) were retrospectively analyzed.RESULTS:The most common initial clinical features of the patients were intermittent abdominal discomfort or vague abdominal pain(67.4%),abdominal mass(31.2%),bowel obstruction(24.1%),hemotochezia(21.3%),jaundice(16.3%),fever(14.2%),coexistence of bowel perforation and peritonitis(5.7%),coexistence of gastrointestinal bleeding and shock(5.0%),and intraabdominal bleeding(1.4%).Ileum was the most common site of tumor(44.7%),followed by jejunum(30.5%)and duodenum(24.8%).PMTSB had a nonspecific clinical presentation.Segmental bowel resection(n=81)was the most common surgical procedure,followed by right hemicolectomy(n=15),pancreaticoduodenectomy(n=10),and others(n=19).Twenty-seven adenocarcinoma patients and 13 malignant lymphoma patients received adjuvant chemotherapy with 5-fluorouracil and cyclophosphamide,adriamycin,vincristine and prednisone,respectively.Information about 120 patients was obtained during the follow-up.The median survival time of PMTSB patients was 20.3 mo.The 1-,3-and 5-year survival rate was 75.0%(90/120),40.0%(48/120)and 20.8%(25/120),respectively.Adenocarcinoma was found in 73.7%(42/57),21.1%(12/57)and 15.8%(9/57)of the patients,respec-tively.Gastrointestinal stromal tumor was observed in 80.0%(20/25),72.0%(18/25)and 36.0%(9/25)of the patients,respectively.Carcinoid was detected in 100.0%(15/15),80.0%(12/15)and 46.7%(7/15)of the patients,respectively.Malignant lymphoma was demonstrated in 69.2%(9/13),30.8%(4/13)and 0%(0/13)of the patients,respectively.CONCLUSION:En bloc resection is the principal therapy for most PMTSB and chemotherapy is the important treatment modality for malignant lymphoma and other malignant tumors of small bowel which cannot be radically removed. 展开更多
关键词 Small bowel Malignant tumor diagnosis surgical treatment CHEMOTHERAPY
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Contribution of Cytology for the Diagnosis of Gallbladder Carcinoma to Avoid Misdiagnosis in This Commonly Resected Organ 被引量:1
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作者 Salah Berkane Salim Belkherchi Ali Bendjaballah 《Surgical Science》 2020年第4期74-81,共8页
The cytological study of gallbladder bile is a diagnostic tool used very often in the treatment of gallbladder cancer. The diagnosis of gall bladder cancer is done by morphological examinations such as ultrasound, com... The cytological study of gallbladder bile is a diagnostic tool used very often in the treatment of gallbladder cancer. The diagnosis of gall bladder cancer is done by morphological examinations such as ultrasound, computed tomography in 80% of cases, but in some difficult cases, benign lesions associated with malignant lesions, such as pseudo-tumoral cholecystitis, adenomyosis or adenoma and cancers requiring medical treatment by chemotherapy or radiotherapy, is without the possibility of surgical treatment. Cytology can help resolve a number of difficult situations, such as the presence of an intra-gallbladder lesion in the form of a polyp or nodule. Some studies have reported very interesting results from gallbladder cytology to cancer diagnosis with results up to 85% sensitivity. The purpose of this study is to analyze the contribution of the cytological study of gallbladder bile to the positive diagnosis of gallbladder cancer. 展开更多
关键词 Cytological Study GALLBLADDER diagnosis of GALLBLADDER Cancer surgical treatment Diagnostic Tool
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Strangulated Femoral Hernia: A Challenging Surgical Vignette —Case Report and Review of Literature
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作者 Ketan Vagholkar 《International Journal of Clinical Medicine》 2014年第2期72-75,共4页
External hernia is one of the commonest causes of intestinal obstruction. Femoral hernia is a relatively uncommon hernia. It has a very high complication rate due to delayed diagnosis caused by deceptive symptomatolog... External hernia is one of the commonest causes of intestinal obstruction. Femoral hernia is a relatively uncommon hernia. It has a very high complication rate due to delayed diagnosis caused by deceptive symptomatology and subtle signs. CT scan enables a prompt diagnosis. Rigorous resuscitation followed by prompt surgical intervention is the mainstay of treatment. A case of a strangulated femoral hernia in a patient with complicated co morbid medical disorders is presented to highlight the pitfalls in initial clinical assessment. 展开更多
关键词 Strangulated FEMORAL HERNIA diagnosis surgical treatment
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中国《CACA甲状腺癌诊治指南(2022版)》外科视角解读 被引量:3
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作者 彭颖 程若川 《西安交通大学学报(医学版)》 CSCD 北大核心 2024年第1期28-34,共7页
外科手术切除是大多数甲状腺癌(thyroid cancer,TC)患者的标准治疗方法,对TC的预后具有至关重要的意义。而明确TC的手术适应证,规范TC的手术方法并制定合理化、个性化的治疗策略,是外科治疗达到疗效最大化的关键。近年来全球范围内针对T... 外科手术切除是大多数甲状腺癌(thyroid cancer,TC)患者的标准治疗方法,对TC的预后具有至关重要的意义。而明确TC的手术适应证,规范TC的手术方法并制定合理化、个性化的治疗策略,是外科治疗达到疗效最大化的关键。近年来全球范围内针对TC诊疗相关的指南共识相继迅速更新,亟需与时俱进、覆盖疾病全程、适合中国国情的综合性指南。在此背景下,中国抗癌协会(CACA)首部涵盖所有病理类型的TC诊治指南《中国肿瘤整合诊治指南-CACA甲状腺癌诊治指南》(简称2022版CACA指南)于2022年4月正式发布。本文结合笔者个人临床经验,以外科视角从分化型TC(DTC)的诊断、初始治疗和术后随访三个方面对2022版CACA指南内容进行解读,探讨外科治疗策略在TC诊治全程管理中的特殊性及其价值,并指出了未来仍需探索研究的相关领域。 展开更多
关键词 CACA甲状腺癌诊治指南 甲状腺癌 指南解读 外科手术策略
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