After primary analyses on the serum glycocon-jugates of lung cancer and normal individul using the enzyme-linked lectin assay (ELLA) with 12 kinds of lectins, PHA and LCA were selected to further study in the sera of ...After primary analyses on the serum glycocon-jugates of lung cancer and normal individul using the enzyme-linked lectin assay (ELLA) with 12 kinds of lectins, PHA and LCA were selected to further study in the sera of 8 kinds of cancers, 4 kinds of non-malignant disease and 1 kind of postoperative cancer. It was found that the test values of 7 kinds of cancers with PHA or LCA were significantly higher than that of the normal (P<0.01); the values of 4 kinds of non-malignant diseases with PHA were not higher (P>0.05); the values of the postoperative cancer with PHA were obviously lower than that of the preoperative (P<0.05). The results showed that the serum glycoconjugates which can bind to PHA seemed related to the cancerous existence in human bodies. The significance of the findings was discussed.展开更多
Patients with cancer are at increased risk of SARA-CoV-2 infection or developing severe COVID-19 cases due to malignancy or immunosuppressive therapy,but they are generally excluded from the target population for COVI...Patients with cancer are at increased risk of SARA-CoV-2 infection or developing severe COVID-19 cases due to malignancy or immunosuppressive therapy,but they are generally excluded from the target population for COVID-19 vaccination.In general,inactivated vaccines are safe and immunogenic for patients with cancer,but live attenuated vaccines are not recommended.The study suggested that the safety of the mRNA COVID-19 vaccine in patients with cancer is similar to that in healthy people,but immunogenicity is slightly weaker,and a booster dose may be needed.This paper aims to summarize the results of COVID-19 vaccine clinical studies conducted in patients with cancer worldwide and the relevant guidelines released by authorities,so as to provide evidence for promoting COVID-19 vaccination for patients with cancer.展开更多
Purpose: This study aimed to identify the challenges and strategies of nurses in facilitating dialogue between patients with terminal cancer and their families in the post-COVID-19 phase. Methods: An online questionna...Purpose: This study aimed to identify the challenges and strategies of nurses in facilitating dialogue between patients with terminal cancer and their families in the post-COVID-19 phase. Methods: An online questionnaire was administered to 839 nurses with at least two years of clinical experience. The questionnaire included items on challenges and strategies in supporting dialogue between patients with terminal cancer and their families, as well as free-response statements. All responses were subjected to inductive qualitative analysis. Results: A total of 193 responses were received and analyzed. The difficulties faced by nurses in supporting dialogue were classified into six categories: “environmental restrictions on visits and dialogue due to infection control” on the organizational side, “inability to be fully involved in dialogue support due to COVID-19,” “influence of nurses’ values regarding death and family,” “insufficient skills of nurses in supporting dialogue,” “lack of cooperation within the team,” and “differences in how the patient and family perceive the disease, hindering dialogue” on the patient and family side. Conversely, five effective strategies for dialogue support were identified: “building trust by understanding the family daily,” “facilitating dialogue between the patient and family despite visitation restrictions,” “assessing the patient and family to guide dialogue,” “encouraging the patient and family to share their thoughts,” and “improving team quality in dialogue support.” Conclusion: The findings suggest that when facing difficulties in dialogue support, a system enabling nurses to reflect on and learn from their practice is needed.展开更多
Clinical communication is a multidimensional concept, which encompasses the core of effective clinical practice. Communication in cancer patients is particularly challenging and yet a less focused area in cancer care....Clinical communication is a multidimensional concept, which encompasses the core of effective clinical practice. Communication in cancer patients is particularly challenging and yet a less focused area in cancer care. Various barriers and challenges in communication may affect the management protocol of cancer patients. Challenges may arise in various dimensions of cancer care including breaking bad news to delivery of complex clinical information, determination of appropriate treatment strategies, dealing with uncertainties, end of life counseling as well as cultural and language barriers affecting the whole communication dynamics. Effective communication is the basic foundation for responsive treatment decisions, positive health outcome, patient driven compliance and overall high quality of care. Thus, there is a need for acknowledging and actively deciphering the challenges and developing and promoting various protocols of effective communication skills in cancer patients.展开更多
文摘After primary analyses on the serum glycocon-jugates of lung cancer and normal individul using the enzyme-linked lectin assay (ELLA) with 12 kinds of lectins, PHA and LCA were selected to further study in the sera of 8 kinds of cancers, 4 kinds of non-malignant disease and 1 kind of postoperative cancer. It was found that the test values of 7 kinds of cancers with PHA or LCA were significantly higher than that of the normal (P<0.01); the values of 4 kinds of non-malignant diseases with PHA were not higher (P>0.05); the values of the postoperative cancer with PHA were obviously lower than that of the preoperative (P<0.05). The results showed that the serum glycoconjugates which can bind to PHA seemed related to the cancerous existence in human bodies. The significance of the findings was discussed.
文摘Patients with cancer are at increased risk of SARA-CoV-2 infection or developing severe COVID-19 cases due to malignancy or immunosuppressive therapy,but they are generally excluded from the target population for COVID-19 vaccination.In general,inactivated vaccines are safe and immunogenic for patients with cancer,but live attenuated vaccines are not recommended.The study suggested that the safety of the mRNA COVID-19 vaccine in patients with cancer is similar to that in healthy people,but immunogenicity is slightly weaker,and a booster dose may be needed.This paper aims to summarize the results of COVID-19 vaccine clinical studies conducted in patients with cancer worldwide and the relevant guidelines released by authorities,so as to provide evidence for promoting COVID-19 vaccination for patients with cancer.
文摘Purpose: This study aimed to identify the challenges and strategies of nurses in facilitating dialogue between patients with terminal cancer and their families in the post-COVID-19 phase. Methods: An online questionnaire was administered to 839 nurses with at least two years of clinical experience. The questionnaire included items on challenges and strategies in supporting dialogue between patients with terminal cancer and their families, as well as free-response statements. All responses were subjected to inductive qualitative analysis. Results: A total of 193 responses were received and analyzed. The difficulties faced by nurses in supporting dialogue were classified into six categories: “environmental restrictions on visits and dialogue due to infection control” on the organizational side, “inability to be fully involved in dialogue support due to COVID-19,” “influence of nurses’ values regarding death and family,” “insufficient skills of nurses in supporting dialogue,” “lack of cooperation within the team,” and “differences in how the patient and family perceive the disease, hindering dialogue” on the patient and family side. Conversely, five effective strategies for dialogue support were identified: “building trust by understanding the family daily,” “facilitating dialogue between the patient and family despite visitation restrictions,” “assessing the patient and family to guide dialogue,” “encouraging the patient and family to share their thoughts,” and “improving team quality in dialogue support.” Conclusion: The findings suggest that when facing difficulties in dialogue support, a system enabling nurses to reflect on and learn from their practice is needed.
文摘Clinical communication is a multidimensional concept, which encompasses the core of effective clinical practice. Communication in cancer patients is particularly challenging and yet a less focused area in cancer care. Various barriers and challenges in communication may affect the management protocol of cancer patients. Challenges may arise in various dimensions of cancer care including breaking bad news to delivery of complex clinical information, determination of appropriate treatment strategies, dealing with uncertainties, end of life counseling as well as cultural and language barriers affecting the whole communication dynamics. Effective communication is the basic foundation for responsive treatment decisions, positive health outcome, patient driven compliance and overall high quality of care. Thus, there is a need for acknowledging and actively deciphering the challenges and developing and promoting various protocols of effective communication skills in cancer patients.
