Expression and clinical significance of pattern recognition receptor-associated genes in hand, foot and mouth disease

Objective:To explore which pattern recognition receptors(PRRs)play a key role in the development of hand,foot,and mouth disease(HFMD)by analyzing PRR-associated genes.Methods:We conducted a comparative analysis of PRR-associated gene expression in human peripheral blood mononuclear cells(PBMCs)infected with enterovirus 71(EV-A71)which were derived from patients with HFMD of different severities and at different stages.A total of 30 PRR-associated genes were identified as significantly upregulated both over time and across different EV-A71 isolates.Subsequently,ELISA was employed to quantify the expression of the six most prominent genes among these 30 identified genes,specifically,BST2,IRF7,IFI16,TRIM21,MX1,and DDX58.Results:Compared with those at the recovery stage,the expression levels of BST2(P=0.027),IFI16(P=0.016),MX1(P=0.046)and DDX58(P=0.008)in the acute stage of infection were significantly upregulated,while no significant difference in the expression levels of IRF7(P=0.495)and TRIM21(P=0.071)was found between different stages of the disease.The expression levels of BST2,IRF7,IFI16 and MX1 were significantly higher in children infected with single pathogen than those infected with mixed pathogens,and BST2,IRF7,IFI16 and MX1 expression levels were significantly lower in coxsackie B virus(COXB)positive patients than the negative patients.Expression levels of one or more of BST2,IRF7,IFI16,TRIM21,MX1 and DDX58 genes were correlated with PCT levels,various white blood cell counts,and serum antibody levels that reflect disease course of HFMD.Aspartate aminotransferase was correlated with BST2,MX1 and DDX58 expression levels.Conclusions:PRR-associated genes likely initiate the immune response in patients at the acute stage of HFMD.

Overcoming the Limits of Cross-Sensitivity:Pattern Recognition Methods for Chemiresistive Gas Sensor Array

As information acquisition terminals for artificial olfaction,chemiresistive gas sensors are often troubled by their cross-sensitivity,and reducing their cross-response to ambient gases has always been a difficult and important point in the gas sensing area.Pattern recognition based on sensor array is the most conspicuous way to overcome the cross-sensitivity of gas sensors.It is crucial to choose an appropriate pattern recognition method for enhancing data analysis,reducing errors and improving system reliability,obtaining better classification or gas concentration prediction results.In this review,we analyze the sensing mechanism of crosssensitivity for chemiresistive gas sensors.We further examine the types,working principles,characteristics,and applicable gas detection range of pattern recognition algorithms utilized in gas-sensing arrays.Additionally,we report,summarize,and evaluate the outstanding and novel advancements in pattern recognition methods for gas identification.At the same time,this work showcases the recent advancements in utilizing these methods for gas identification,particularly within three crucial domains:ensuring food safety,monitoring the environment,and aiding in medical diagnosis.In conclusion,this study anticipates future research prospects by considering the existing landscape and challenges.It is hoped that this work will make a positive contribution towards mitigating cross-sensitivity in gas-sensitive devices and offer valuable insights for algorithm selection in gas recognition applications.

Spatial pattern recognition for near-surface high temperature increases in mountain areas using MODIS and SRTM DEM

Abrupt near-surface temperature changes in mountainous areas are a special component of the mountain climate system.Fast and accurate measurements of the locations,intensity,and width of the near-surface changes are necessary but highly difficult due to the complicated environmental conditions and instrumental issues.This paper develops a spatial pattern recognition method to measure the near-surface high temperature increase(NSHTI),one of the lesser-attended changes.First,raster window measurement was proposed to calculate the temperature lapse rate using MODIS land surface temperature and SRTM DEM data.It fully considers the terrain heights of two neighboring cells on opposite or adjacent slopes with a moving window of 3×3 cell size.Second,a threshold selection was performed to identify the NSHTI cells using a threshold of-0.65℃/100 m.Then,the NSHTI strips were parameterized through raster vectorization and spatial analysis.Taking Yunnan,a mountainous province in southwestern China,as the study area,the results indicate that the NSHTI cells concentrate in a strip-like pattern along the mountains and valleys,and the strips are almost parallel to the altitude contours with a slight northward uplift.Also,they are located mostly at a 3/5 height of high mountains or within 400 m from the valley floors,where the controlling topographic index is the altitude of the terrain trend surface but not the absolute elevation and the topographic uplift height and cutting depth.Additionally,the NSHTI intensity varies with the geographic locations and the proportions increase with an exponential trend,and the horizontal width has a mean of about 1000 m and a maximum of over 5000 m.The result demonstrates that the proposed method can effectively recognize NSHTI boundaries over mountains,providing support for the modeling of weather and climate systems and the development of mountain resources.

Dynamic Signature Verification Using Pattern Recognition

Dynamic signature is a biometric modality that recognizes an individual’s anatomic and behavioural characteristics when signing their name. The rampant case of signature falsification (Identity Theft) was the key motivating factor for embarking on this study. This study was necessitated by the damages and dangers posed by signature forgery coupled with the intractable nature of the problem. The aim and objectives of this study is to design a proactive and responsive system that could compare two signature samples and detect the correct signature against the forged one. Dynamic Signature verification is an important biometric technique that aims to detect whether a given signature is genuine or forged. In this research work, Convolutional Neural Networks (CNNsor ConvNet) which is a class of deep, feed forward artificial neural networks that has successfully been applied to analysing visual imagery was used to train the model. The signature images are stored in a file directory structure which the Keras Python library can work with. Then the CNN was implemented in python using the Keras with the TensorFlow backend to learn the patterns associated with the signature. The result showed that for the same CNNs-based network experimental result of average accuracy, the larger the training dataset, the higher the test accuracy. However, when the training dataset are insufficient, better results can be obtained. The paper concluded that by training datasets using CNNs network, 98% accuracy in the result was recorded, in the experimental part, the model achieved a high degree of accuracy in the classification of the biometric parameters used.

Crack Fault Diagnosis and Location Method for a Dual-Disk Hollow Shaft Rotor System Based on the Radial Basis Function Network and Pattern Recognition Neural Network

The crack fault is one of the most common faults in the rotor system,and researchers have paid close attention to its fault diagnosis.However,most studies focus on discussing the dynamic response characteristics caused by the crack rather than estimating the crack depth and position based on the obtained vibration signals.In this paper,a novel crack fault diagnosis and location method for a dual-disk hollow shaft rotor system based on the Radial basis function(RBF)network and Pattern recognition neural network(PRNN)is presented.Firstly,a rotor system model with a breathing crack suitable for a short-thick hollow shaft rotor is established based on the finite element method,where the crack's periodic opening and closing pattern and different degrees of crack depth are considered.Then,the dynamic response is obtained by the harmonic balance method.By adjusting the crack parameters,the dynamic characteristics related to the crack depth and position are analyzed through the amplitude-frequency responses and waterfall plots.The analysis results show that the first critical speed,first subcritical speed,first critical speed amplitude,and super-harmonic resonance peak at the first subcritical speed can be utilized for the crack fault diagnosis.Based on this,the RBF network and PRNN are adopted to determine the depth and approximate location of the crack respectively by taking the above dynamic characteristics as input.Test results show that the proposed method has high fault diagnosis accuracy.This research proposes a crack detection method adequate for the hollow shaft rotor system,where the crack depth and position are both unknown.

Numerical Comparison of Shapeless Radial Basis Function Networks in Pattern Recognition

This work focuses on radial basis functions containing no parameters with themain objective being to comparatively explore more of their effectiveness.For this,a total of sixteen forms of shapeless radial basis functions are gathered and investigated under the context of the pattern recognition problem through the structure of radial basis function neural networks,with the use of the Representational Capability(RC)algorithm.Different sizes of datasets are disturbed with noise before being imported into the algorithm as‘training/testing’datasets.Each shapeless radial basis function is monitored carefully with effectiveness criteria including accuracy,condition number(of the interpolation matrix),CPU time,CPU-storage requirement,underfitting and overfitting aspects,and the number of centres being generated.For the sake of comparison,the well-known Multiquadric-radial basis function is included as a representative of shape-contained radial basis functions.The numerical results have revealed that some forms of shapeless radial basis functions show good potential and are even better than Multiquadric itself indicating strongly that the future use of radial basis function may no longer face the pain of choosing a proper shape when shapeless forms may be equally(or even better)effective.

Hierarchical pattern recognition of landform elements considering scale adaptation

Landform elements with varying morphologies and spatial arrangements are recognized as feature indicator of landform classification and play a critical role in geomorphological studies.Differential geometry method has been extensively applied in prior landform element research,while its efficacy in differentiating similar morphological characteristics remains inadequate to date.To reduce reliance on geomorphometric variables and increase awareness of landform patterns,geomorphons method was generated in previous study corresponding to specific landform reclassification map based on lookup table.Besides,to address the problem of feature similarity,hierarchical classification was proposed and effectively utilized for terrain recognition through the analytical strategy of fuzzy gradient features.Thus,combining the advantages of these two aspects,a hierarchical framework was proposed in this study for landform element pattern recognition considering the morphology and hierarchy factors.First,the local triplet patterns derived from geomorphons were enhanced by setting the flatness threshold,and subsequently adopted for the primary landform element recognition.Then,as geomorphic units with the same morphology possess different spatial analytical scales,the unidentified landform elements under the principle of scale adaptation were determined by calculating the spatial correlation and entropy information.To ensure the effectiveness of this proposed method,the sampling points were randomly selected from NASADEM data and then validated against a real 3D terrain model.Quantitative results of landform element pattern recognition demonstrate that our approach can reach above 77%average accuracy.Additionally,it delineates local details more effectively than geomorphons in visual assessment,resulting in a 7%accuracy improvement in overall scale.

Recognition model and algorithm of projectiles by combining particle swarm optimization support vector and spatial-temporal constrain

In order to improve the recognition rate and accuracy rate of projectiles in six sky-screens intersection test system,this work proposes a new recognition method of projectiles by combining particle swarm optimization support vector and spatial-temporal constrain of six sky-screens detection sensor.Based on the measurement principle of the six sky-screens intersection test system and the characteristics of the output signal of the sky-screen,we analyze the existing problems regarding the recognition of projectiles.In order to optimize the projectile recognition effect,we use the support vector machine and basic particle swarm algorithm to form a new recognition algorithm.We set up the particle swarm algorithm optimization support vector projectile information recognition model that conforms to the six sky-screens intersection test system.We also construct a spatial-temporal constrain matching model based on the spatial geometric relationship of six sky-screen intersection,and form a new projectile signal recognition algorithm with six sky-screens spatial-temporal information constraints under the signal classification mechanism of particle swarm optimization algorithm support vector machine.Based on experiments,we obtain the optimal penalty and kernel function radius parameters in the PSO-SVM algorithm;we adjust the parameters of the support vector machine model,train the test signal data of every sky-screen,and gain the projectile signal classification results.Afterwards,according to the signal classification results,we calculate the coordinate parameters of the real projectile by using the spatial-temporal constrain of six sky-screens detection sensor,which verifies the feasibility of the proposed algorithm.

Human Personality Assessment Based on Gait Pattern Recognition Using Smartphone Sensors

Human personality assessment using gait pattern recognition is one of the most recent and exciting research domains.Gait is a person’s identity that can reflect reliable information about his mood,emotions,and substantial personality traits under scrutiny.This research focuses on recognizing key personality traits,including neuroticism,extraversion,openness to experience,agreeableness,and conscientiousness,in line with the bigfive model of personality.We inferred personality traits based on the gait pattern recognition of individuals utilizing built-in smartphone sensors.For experimentation,we collected a novel dataset of 22 participants using an android application and further segmented it into six data chunks for a critical evaluation.After data pre-processing,we extracted selected features from each data segment and then applied four multiclass machine learning algorithms for training and classifying the dataset corresponding to the users’Big-Five Personality Traits Profiles(BFPT).Experimental results and performance evaluation of the classifiers revealed the efficacy of the proposed scheme for all big-five traits.

Fuzzy pattern recognition model of geological sweetspot for coalbed methane development

From the perspective of geological zone selection for coalbed methane(CBM) development, the evaluation parameters(covering geological conditions and production conditions) of geological sweetspot for CBM development are determined, and the evaluation index system of geological sweetspot for CBM development is established. On this basis, the fuzzy pattern recognition(FPR) model of geological sweetspot for CBM development is built. The model is applied to evaluate four units of No.3 Coal Seam in the Fanzhuang Block, southern Qinshui Basin, China. The evaluation results are consistent with the actual development effect and the existing research results, which verifies the rationality and reliability of the FPR model. The research shows that the proposed FPR model of geological sweetspot for CBM development does not involve parameter weighting which leads to uncertainties in the results of the conventional models such as analytic hierarchy process and multi-level fuzzy synthesis judgment, and features a simple computation without the construction of multi-level judgment matrix. The FPR model provides reliable results to support the efficient development of CBM.

Authentication and distinction of Shenmai injection with HPLC fingerprint analysis assisted by pattern recognition techniques

In this paper, the feasibility and advantages of employing high performance liquid chromatographic （HPLC） fingerprints combined with pattern recognition techniques for quality control of Shenmai injection were investigated and demonstrated. The Similarity Evaluation System was employed to evaluate the similarities of samples of Shenmai injection, and the HPLC generated chromatographic data were analyzed using hierarchical clustering analysis （HCA） and soft independent modeling of class analogy （SIMCA）. Consistent results were obtained to show that the authentic samples and the blended samples were successfully classified by SIMCA, which could be applied to accurate discrimination and quality control of Shenmai injection. Furthermore, samples could also be grouped in accordance with manufacturers. Our results revealed that the developed method has potential perspective for the original discrimination and quality control of Shenmai injection.

Pattern recognition and data mining software based on artificial neural networks applied to proton transfer in aqueous environments

In computational physics proton transfer phenomena could be viewed as pattern classification problems based on a set of input features allowing classification of the proton motion into two categories： transfer ＇occurred＇ and transfer ＇not occurred＇. The goal of this paper is to evaluate the use of artificial neural networks in the classification of proton transfer events, based on the feed-forward back propagation neural network, used as a classifier to distinguish between the two transfer cases. In this paper, we use a new developed data mining and pattern recognition tool for automating, controlling, and drawing charts of the output data of an Empirical Valence Bond existing code. The study analyzes the need for pattern recognition in aqueous proton transfer processes and how the learning approach in error back propagation （multilayer perceptron algorithms） could be satisfactorily employed in the present case. We present a tool for pattern recognition and validate the code including a real physical case study. The results of applying the artificial neural networks methodology to crowd patterns based upon selected physical properties （e.g., temperature, density） show the abilities of the network to learn proton transfer patterns corresponding to properties of the aqueous environments, which is in turn proved to be fully compatible with previous proton transfer studies.

ON THE IDENTIFICATION OF RESIDUAL IMPACT PROPERTIES OF MATERIALS BY ACOUSTO-ULTRASONICS——A PATTERN RECOGNITION APPROACH

This paper deals with the application of Acousto-ultrasonics,in con- junction with Pattern Recognition and Classification techniques,to the identification of residual impact properties of a class of polymeric material,namely,Polyvinylchlo- ride(PVC).PVC specimens of different low-energy repeated impact damage states are processed by Acousto-ultrasonics(AU)to retrieve AU signals in the form of dig- italized records.These AU signals are grouped as distinct classes,each pertaining to a known level of repeated impact damage.Describing features of these AU signals are used to build Pattern Recognition(PR)Classifiers.These classifiers are used to identify unknown damage states in other PVC specimens by classifying the re- trieved AU signals as belonging to one of the classes.The obtained results indicate that Acousto-ultrasonics in combination with Pattern Recognition and Classification techniques can be used for the quantitative non-destructive identification of damage states in PVC specimens of unknown low-energy repeated impact conditions.

Practical Pattern Recognition System for Distributed Optical Fiber Intrusion Monitoring Based on Ф-COTDR

At present, the demand for perimeter security system is in-creasing greatly, especially for such system based on distribut-ed optical fiber sensing. This paper proposes a perimeter se-curity monitoring system based on phase-sensitive coherentoptical time domain reflectometry(Ф-COTDR) with the practi-cal pattern recognition function. We use fast Fourier trans-form(FFT) to exact features from intrusion events and a multi-class classification algorithm derived from support vector ma-chine(SVM) to work as a pattern recognition technique. Fivedifferent types of events are classified by using a classifica-tion algorithm based on SVM through a three-dimensional fea-ture vector. Moreover, the identification results of the patternrecognition system show that an identification accurate rate of92.62% on average can be achieved.

Application study of image segmentation methods on pattern recognition in the course of wood across-compression

Image segmentation is one of important steps on pattern recognition study in the course of wood across-compression. By comparing and studying processing methods in finding cell space and cell wall, this paper puts forward some image segmentation methods that are suitable for study of cell images of wood crossgrained compression. The method of spline function fitting was used for linking edges of cell, which perfects the study of pattern recognition in the course of wood across-compression.

MOLTEN SALT PHASE DIAGRAMS CALCULATION USING ARTIFICIAL NEURAL NETWORK OR PATTERN RECOGNITION-BOND PARAMETERS Part 2.Prediction of phase diagrams of ternary molten salt systems

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Investigation and Application of Automatic Fingerprint Identification Based on Fuzzy Pattern Recognition

Fingerprint image is a typical non-restraint image that has some uncertainty, which makes it difficult to perform identification using classical approach. Therefore, fuzzy pattern recognition is applied to match individual query by searching the entire template database. The fuzzy maximum subordinate principle is used to solve shift matching. Through experimenting and analyzing, the approximate principle fuzzy method is employed by selecting fuzzy characteristics and determining the similarity function to achieve the further accuracy. Theoretical and experimental results show this approach is effective and reasonable.

Pattern recognition and prediction study of rock burst based on neural network

Many monitoring measures were used in the production field for predicting rockburst.However, predicting rock burst according to complicated observation data is alwaysa pressing problem in this research field.Though the critical value method gets extensiveapplication in practice, it stresses only on the superficial change of data and overlooks alot of features of rock burst and useful information that is concealed and hidden in the observationtime series.Pattern recognition extracts the feature value of time domain, frequencydomain and wavelet domain in observation time series to form Multi-Feature vectors,using Euclidean distance measure as the separable criterion between the same typeand different type to compress and transform feature vectors.It applies neural network asa tool to recognize the danger of rock burst, and uses feature vectors being compressedto carry out training and studying.It is proved by test samples that predicting precisionshould be prior to such traditional predicting methods as pattern recognition and critical indicatormethod.

A systematic method based on statistical pattern recognition for estimating product quality on-line

To avoid the complexity of building mechanistic models by studying the inner nature of the object, a systematic method based on statistical pattern recognition is developed in order to estimate the product quality on-line. The mapping relationship between a feature space and a product quality space can be built by using regression analysis, and in applying clustering analysis the product quality space can be partitioned automatically. Eventually, estimating product quality on-line can be accomplished by sorting the mapped data in the partitioned quality space. A concrete problem is proposed which has a relatively small ratio of training data to input variables. By implementing the method mentioned above, a satisfying result has been achieved. Furthermore, the further question about choosing suitable mapping methods is briefly discussed.

Raman spectroscopy for human cancer tissue diagnosis: A pattern recognition approach

In this work, optical scattering using Raman spectroscopy has been analyzed for various cancer tissues. The Raman shifts obtained at the Indiana University Bloomington (IUB) and Indiana University-Purdue University Indianapolis (IUPUI) laboratories have been processed for diagnosing various types of cancer tissues. The objective of this research is to distinguish between cancerous and non-cancerous tissues. Small size tissue samples have been processed, seeking the minimum size tissue that can be diagnosed via Raman spectroscopy. The tests have been conducted on nearly 20 human tissues. A Matlab program has been written following Parzen-Window classifier to recognize the Raman shift pattern for various types of cancer tissues, including breast cancer, kidney, and Gyn-Uterus. A software visual model has been used for data processing. Unique signals for breast and kidney tumors have been obtained. The approach followed in this paper shows promise for early cancer detection in humans.