Systematic evaluation of a holmium:yttrium-aluminum-garnet laser lithotripsy device with variable pulse peak power and pulse duration

Objective:The Holmium:yttrium-aluminum-garnet(Ho:YAG)laser is the standard lithotrite for ureteroscopy.This paper is to evaluate a Ho:YAG laser with a novel effect function in vitro,which allows a real-time variation of pulse duration and pulse peak power.Methods:Two types of phantom calculi with four degrees of hardness were made for fragmentation and retropulsion experiments.Fragmentation was analysed at 5(0.5 J/10 Hz),10(1 J/10 Hz),and 20(2 J/10 Hz)W in non-floating phantom calculi,retropulsion in an ureteral model at 10(1 J/10 Hz)and 20(2 J/10 Hz)W using floating phantom calculi.The effect function was set to 25%,50%,75%,and 100%of the maximum possible effect function at each power setting.Primary outcomes:fragmentation(mm^3),the distance of retropulsion(cm);
5 measurements for each trial.Results:An increase of the effect feature(25%vs.100%),i.e.,an increase of pulse peak power and decrease of pulse duration,improved Ho:YAG laser fragmentation.This effect was remarkable in soft stone composition,while there was a trend for improved fragmentation with an increase of the effect feature in hard stone composition.Retropulsion increased with increasing effect function,independently of stone composition.The major limitations of the study are the use of artificial stones and the in vitro setup.Conclusion:Changes in pulse duration and pulse peak power may lead to improved stone fragmentation,most prominently in soft stones,but also lead to increased retropulsion.This new effect function may enhance Ho:YAG laser fragmentation when maximum power output is limited or retropulsion is excluded.

Effects on the Behavior and Neuroimmunity of Pulsed Microwaves with Different Peak Densities

Pulsed microwaves are widely used inradar,navigation, and communication. The average power density is low at narrow pulse widths or large pulse intervals,but pulsed microwaves at certain peak densities exert numerous biological effects, including

A Modified Code Domain Transmitted Reference UWB System

Based on the research on time domain and frequency domain transmitted reference Impulse Radio Ultra-WideBand (IR-UWB) system, this paper studies the optimization design for code domain transmitted reference IR-UWB system, and proposes a modified code domain transmitted reference IR-UWB system. The Bit Error Rate (BER) expressions for the modified system model in the condition of Additive White Gaussian Noise (AWGN) and multipath fading are deduced respectively. In addition, the performances of the modified system and the other three transmitted reference IR-UWB systems are simulated and compared. Theoretical analysis and simulation results show that the performance of the modified system is superior to the other three systems.

High peak power subnanosecond pulse characteristics with different wall structured CNTs in a doubly QML Nd:Lu_(0.15)Y_(0.85)VO_4 laser

By simultaneously employing both an electro-optic modulator and carbon nanotube saturable absorber(CNT-SA)in a dual-loss modulator, a subnanosecond single mode-locking pulse underneath a Q-switched envelope with high peak power was generated from a doubly Q-switched and mode-locked(QML) Nd:Lu_(0.15)Y_(0.85)VO_4 laser at1.06 μm for the first time, to our knowledge. CNTs with different wall structures—single-walled CNTs(SWCNTs),double-walled CNTs(DWCNTs), and multi-walled CNTs(MWCNTs)—were used as SAs in the experiment to investigate the single mode-locking pulse characteristics. At pump power of 10.72 W, the maximum peak power of1.312 MW was obtained with the DWCNT.