Superoxide Dismutase and Malondialdehyde Levels in Serum of Dairy Cows with Perinatal Diseases

[Objective] To investigate the relationship between perinatal diseases and contents of superoxide dismutase （SOD） and malondialde- hyde （MDA） in serum of dairy cows. [ Method] A total of 38 dairy cows including 22 healthy cows, five cows with ketosis, four cows with fatty liver and seven cows with retained fatal placenta in perinatal period were selected. The contents of SOD and MDA in serum were respectively determined at different times ante partum and post partum. [Result] In the dairy cows with perinatal diseases, the SOD activity is lower and the MDA content was higher than that in the healthy dairy cows during perinatal period. [Conclusion] The antioxidant activity of dairy cows with perinatal diseases is lower than that of healthy dairy cows during perinatal period.

COVID-19 associated liver injury:A general review with special consideration of pregnancy and obstetric outcomes

Liver injury is an increasingly recognized extra-pulmonary manifestation of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection.Coronavirus disease 2019(COVID-19)associated liver injury(COVALI)is a clinical syndrome encompassing all patients with biochemical liver injury identified in the setting of SARS-CoV-2 infection.Despite profound clinical implications,its pathophysiology is poorly understood.Unfortunately,most information on COVALI is derived from the general population and may not be applicable to individuals under-represented in research,including pregnant individuals.This manuscript reviews:Clinical features of COVALI,leading theories of COVALI,and existing literature on COVALI during pregnancy,a topic not widely explored in the literature.Ultimately,we synthesized data from the general and perinatal populations that demonstrates COVALI to be a hepatocellular transaminitis that is likely induced by systemic inflammation and that is strongly associated with disease severity and poorer clinical outcome,and offered perspective on approaching transaminitis in the potentially COVID-19 positive patient in the obstetric setting.