Sir Nicholas Harold Lloyd Ridley has revolutionized the practice of ophthalmology by performing the firstintraocular lens （IOL） implantation in 1949. His scientific achievement was acknowledged thirty years later, w...Sir Nicholas Harold Lloyd Ridley has revolutionized the practice of ophthalmology by performing the firstintraocular lens （IOL） implantation in 1949. His scientific achievement was acknowledged thirty years later, which led to US Food and Drug Administration approval in 1981. Although the basic principles of IOL implantation have not changed since, many efforts have been invested in perfecting IOL design during the past decades.展开更多
AIM:To evaluate the peripheral arterial filling time(PAFT)and venous filling time(VFT)in eyes without known diseases that may influence filling process using ultra-widefield(UWF)fluorescein angiography(FA),and to revi...AIM:To evaluate the peripheral arterial filling time(PAFT)and venous filling time(VFT)in eyes without known diseases that may influence filling process using ultra-widefield(UWF)fluorescein angiography(FA),and to review the peripheral retina fluorescence features.METHODS:A total of 30 eyes of 30 patients were retrospectively reviewed in this observational study.UWFFA was performed using Optos 200Tx.PAFT and VFT was recorded.The interval between the arterial or venous filling completion and the previous photo was documented.The appearance of the far peripheral retina was described as either granular background fluorescence or mottled fluorescent band or vascular leakage.Terminal vascular patterns was described as loop pattern or branching pattern.Microvascular abnormalities such as arteriovenous shunting,vessels crossing the horizontal raphe,right angle vessels,terminal networks,capillary nonperfusion,drusen or microaneurysms were evaluated.RESULTS:The normal limits of PAFT was 3.397-8.984s and 4.399-11.753s for VFT.The appearance of the far peripheral retina,defined as granular background(63%),mottled fluorescence(20%),or vascular leakage(17%),was symmetrical between both eyes.Capillary nonperfusion(23%)and microaneurysms(40%)were more frequently found in eyes with loop pattern than in eyes with branching pattern.Other peripheral signs such as right-angle vessels(73%),and terminal networks(80%)were commonly seen on UWF-FA in the normal peripheral retina.CONCLUSION:The main courses of retinal artery and vein filling time are overlapping with each other on UWF-FA.Notably,the arterial filling process is completed in the arteriovenous phase rather than the traditionally named arterial phase.There are various manifestations in the peripheral retina of normal eyes.展开更多
基金Supported in part by an unrestricted grant from Research to Prevent Blindness,Inc.The American Physician Fellowship for Medicine in Israel
文摘Sir Nicholas Harold Lloyd Ridley has revolutionized the practice of ophthalmology by performing the firstintraocular lens （IOL） implantation in 1949. His scientific achievement was acknowledged thirty years later, which led to US Food and Drug Administration approval in 1981. Although the basic principles of IOL implantation have not changed since, many efforts have been invested in perfecting IOL design during the past decades.
基金Supported by Capital Health Development Research Special Fund(No.2020-2-2053)。
文摘AIM:To evaluate the peripheral arterial filling time(PAFT)and venous filling time(VFT)in eyes without known diseases that may influence filling process using ultra-widefield(UWF)fluorescein angiography(FA),and to review the peripheral retina fluorescence features.METHODS:A total of 30 eyes of 30 patients were retrospectively reviewed in this observational study.UWFFA was performed using Optos 200Tx.PAFT and VFT was recorded.The interval between the arterial or venous filling completion and the previous photo was documented.The appearance of the far peripheral retina was described as either granular background fluorescence or mottled fluorescent band or vascular leakage.Terminal vascular patterns was described as loop pattern or branching pattern.Microvascular abnormalities such as arteriovenous shunting,vessels crossing the horizontal raphe,right angle vessels,terminal networks,capillary nonperfusion,drusen or microaneurysms were evaluated.RESULTS:The normal limits of PAFT was 3.397-8.984s and 4.399-11.753s for VFT.The appearance of the far peripheral retina,defined as granular background(63%),mottled fluorescence(20%),or vascular leakage(17%),was symmetrical between both eyes.Capillary nonperfusion(23%)and microaneurysms(40%)were more frequently found in eyes with loop pattern than in eyes with branching pattern.Other peripheral signs such as right-angle vessels(73%),and terminal networks(80%)were commonly seen on UWF-FA in the normal peripheral retina.CONCLUSION:The main courses of retinal artery and vein filling time are overlapping with each other on UWF-FA.Notably,the arterial filling process is completed in the arteriovenous phase rather than the traditionally named arterial phase.There are various manifestations in the peripheral retina of normal eyes.
