Promoting the Personal Development of Children Through Art Education

With the arrival of the new era,the development of society changes with each passing day,innovative ability and creative thinking skills are increasingly valued by society.The development of innovative ability should start with children.The emergence of new educational concepts requires the school to cultivate students in a comprehensive way.In this case,art and music,which were once considered unimportant,are gradually changing the educational field and are returning to the public eye.Studies have shown that art education plays an important role in promoting personal development of children.Therefore,art education should not be neglected,and we should see that art education plays a certain role in improving children’s innovative abilities.However,there are still many problems in art education for children,which affects its role in promoting their personal development.Therefore,it is important to focus on how to promote children’s personal development through art education.This paper analyzes the problems faced in children’s art education and how to effectively maximize its role of art education to promote the development of children’s art education.

Curriculum Reform of Higher Vocational Mathematics Under the Background of Digital Transformation

Under the background of digital transformation,the reform of the higher vocational mathematics curriculum faces urgent challenges and opportunities.This article explores the impact of digital transformation on the reform of higher vocational mathematics curriculum and emphasizes the importance of improving teaching methods centered on learners.The article proposes specific reform methods and discusses the practical application of digital technology in the reform process.By combining digital technology with specific reform methods,further conducting innovative practice research,and continuously exploring the path of reform,we can effectively improve the quality of higher vocational mathematics classroom teaching and provide strong support for the cultivation of comprehensive qualities and employment abilities.

Breast Cancer MCF-7 Cell Spheroid Culture for Drug Discovery and Development

In vitro 3D cancer spheroids (tumoroids) exhibit a drug resistance profile similar to that found in solid tumors. 3D spheroid culture methods recreate more physiologically relevant microenvironments for cells. Therefore, these models are more appropriate for cancer drug screening. We have recently developed a protocol for MCF-7 cell spheroid culture, and used this method to test the effects of different types of drugs on this estrogen-dependent breast cancer cell spheroid. Our results demonstrated that MCF-7 cells can grow spheroid in medium using a low attachment plate. We managed to grow one spheroid in each well, and the spheroid can grow over a month, the size of the spheroid can grow over a hundred times in volume. Our targeted drug experimental results suggest that estrogen sulfotransferase, steroid sulfatase, and G protein-coupled estrogen receptor may play critical roles in MCF-7 cell spheroid growth, while estrogen receptors α and β may not play an essential role in MCF-7 spheroid growth. Organoids are the miniatures of in vivo tissues and reiterate the in vivo microenvironment of a specific organ, best fit for the in vitro studies of diseases and drug development. Tumoroid, developed from cancer cell lines or patients’ tumor tissue, is the best in vitro model of in vivo tumors. 3D spheroid technology will be the best future method for drug development of cancers and other diseases. Our reported method can be developed clinically to develop personalized drugs when the patient’s tumor tissues are used to develop a spheroid culture for drug screening.

Are early maladaptive schemas, temperament and character dimensions correlated?

Objective: Aim of the study is to examine the relationships between early maladaptive schemas and the character and temperament aspects of personality, which are known as two approaches to the understanding of personality structure. Methods: We conducted the study using the Young Schema Questionnaire-Short Form (YSQ-SF) and the Cloninger’s Temperament and Character Inventory (TCI) in 122 university students from different schools. Results and Conclusion: Results demonstrated that there are high level of positive as well as negative correlations between most of TCI items and some of the sub-scales of the YSQ, including vulnerability, social isolation and defectiveness. In consistent with the Halvorsen et al.’s findings, our study demonstrated that harm avoidance had a positive relationship with several EMSs, including emotional deprivation, deficiency, dependence, failure, subjugation and selfsacrifice. More importantly, we obtained the results consistent with theirs regarding the negative correlations between self-directedness and almost all of EMSs, with the exception of the schema of subjugation. We concluded that although some of the personality characteristics contained in the YSQ and the TCI are appeared to be related to each other, we need more studies to support the Young et al.’s suggestion that early maladaptive schemas (EMSs) are likely to reflect underlying characterological factors of personality.

Academic advising system and its application exploring in nursing colleges of China

Review the definition,origin,development and application status of the foreign academic advising system and make a comparison with the Chinese counselor system.Start with the perspectives of the learning difficulties and attrition rate of nursing students to explore the importance and significance of its implementation in Chinese nursing colleges and universities.Meanwhile,present the prototype of the existing academic advising system in China,with the expectation of providing a theoretical basis for the introduction of this system in nursing colleges and universities and the cultivation of high-quality nursing talents.