The Isomerization/Chlorination of O,O-Diallyl Thiophosphoric (-nic) Acid Esters with Phosphorus Oxychloride─A New Convenient Method for Synthesis of S-Alkyl Thiophosphoric(-nic) Acid Derivatives

The isomerization/chlorination of O, O-diallyl thiophosphoric (-nic) acid esters with phosphrus oxychloride gives S-allyl thiophosphoro (-no)chloride, which reacts with subsittuted phenol in chloroform in the presence of triethylamine to afford eighteen new S-allyl thiophosphoric(-nic) acid derivatives. Thus, a new convenient method has been provided for synthesis of the title compounds.

Preparation and Property of Bisphenol A Bis (diphenyl phosphate) Oligomer

Bisphenol A bis（diphenyl phosphate） oligomer（BDP） is prepared successfully from the reactants consisting of phosphorus oxyehloride （POCl3）, bisphenol A and phenol with a Friedel-Crafts catalyst. The resultant products were examined with thermtygravimetrie analysis （TGA） and high performance liquid chro- matography（HPLC）. Thermogravimetry data shows that BDP decomposes at 375℃ when 5 % weight lost. Experiments results show that catalyst is preferably AICI3 and the amount of it is preferably 1% relative to bisphenol A by mole. POCl3/bisphenol A mole ratio is preferably about 5：1 to 6：1. Experiments unclosed that a seal apparatus is very important to the properties of product.

A facile synthesis of ω-aminoalkyl ammonium hydrogen phosphates

A series of og-aminoalkyl ammonium hydrogen phosphates were synthesized through a simple and efficient three-step method. The starting materials, co-aminoalkyl alcohols （AC-n, with carbon number n = 3, 4, 5, 6）, were amino-protected with 9- fluorenylmethyl chloroformate （Fmoc-C1）, followed by phosphorylation with POCI3 and deprotection in piperidine/DME The structures of each intermediate and final product were confirmed by 1H NMR, FTIR and mass spectrum. The yield of each step was about 77-92%, with a total yield higher than 56%. This new method was superior in low-cost raw materials, mild reaction temperatures （0-25 ℃） and easy purification methods.

A simple and efficient procedure for the synthesis of optically active s-triazolothiadiazole derivatives

A series of novel s-triazolothiadiazoles 3a-h were prepared by condensation reaction of substituted amino triazoles 1a-b with N-phethaloyl-L-amino acids 2a-d in the presence of the phosphoroxy chloride （POC13） as an anhydrous reagent. The structure of all synthesized compounds was confirmed by IR, 1H NMR, arid 13C NMR spectroscopy.

A New and Efficient Procedure for Synthesis of 1,5-Benzodiazepine Derivatives in Solution and under Solvent-Free Conditions

Borax/phosphorous oxychloride （BPO） efficiently catalyzes the preparation of 1,5-benzodiazepine derivatives of o-phenylenediamines and ketones in solvent-free and solution conditions. The reaction proceeds efficiently under ambient conditions giving excellent yields of the products. This new protocol allows the recycling of catalyst with no loss in its potency.