The purpose of this study was to assess factors associated with subjective sleep evaluation, chiefly excessive daytime sleepiness (EDS) in obstructive sleep apnea syndrome (OSAS) adult outpatients under continuous pos...The purpose of this study was to assess factors associated with subjective sleep evaluation, chiefly excessive daytime sleepiness (EDS) in obstructive sleep apnea syndrome (OSAS) adult outpatients under continuous positive airway pressure (CPAP) treatment. One thousand and forty-eight OSAS outpatients (mean age: 51.4% male: 90.5%) who were treated by CPAP were consecutively collected. Age, sex, CPAP compliance (CPAP usage as their device of nights with application-time of at least 4 hours per night objectively;%usage ≥ 4 h/d), and Japanese version of the Pittsburgh Sleep Quality Index (PSQI-J) of the patients showing EDS (Japanese version of the Epworth Sleepiness Scale;JESS ≥ 11) were compared cross-sectionally with those of the patients who did not show EDS (JESS < 11). Nineteen point two % of all patients showed EDS subjectively. Two hundred one patients were classified to an EDS(+) group and an 847 patients were classified to EDS(–) group. Age and global PSQI-J scores were significantly different between the two groups. Logistic regression showed that EDS was significantly associated with global PSQI-J scores, but not with age. Among PSQI-J components, overall sleep quality, duration of sleep, sleep disturbance, and day dysfunction due to sleepiness were significantly higher in the EDS(+) group. Especially, 19.4% of patient in the EDS(+) group reported actual sleep time during the past month to be less than 5 hours/day. Although functional relationship should be further evaluated, insufficient sleep is the main factor associated with EDS in the OSAS patients under CPAP treatment.展开更多
目的:运用频率学网状Meta分析评价耳穴贴压相关疗法干预脑卒中后失眠的临床效果。方法:计算机检索中国知网、万方数据库、维普数据库、中国生物医学文献服务系统、PubMed、EMbase、the Cochrane Library、Web of Science,检索时限为建库...目的:运用频率学网状Meta分析评价耳穴贴压相关疗法干预脑卒中后失眠的临床效果。方法:计算机检索中国知网、万方数据库、维普数据库、中国生物医学文献服务系统、PubMed、EMbase、the Cochrane Library、Web of Science,检索时限为建库至2022年8月9日收录的耳穴贴压相关疗法治疗脑卒中后失眠的随机对照试验,按照纳入、排除标准和Cochrane偏倚风险评估工具进行文献筛选和质量评价,采用RevMan 5.4、Stata SE 17进行统计分析。结果:纳入35篇文献,涉及9种干预措施及2780例病人。网状Meta分析显示,临床有效率较高的前4种疗法依次为耳穴贴压联合中药、耳穴贴压联合中药足浴、耳穴贴压联合穴位敷贴、耳穴贴压联合针刺;改善匹兹堡睡眠质量指数(Pittsburgh Sleeping Quality Index,PSQI)评分较好的前4种疗法依次为耳穴贴压联合穴位敷贴、耳穴贴压联合音乐疗法、耳穴贴压联合中药、耳穴贴压联合中药足浴。仅有9篇文献报告不良反应,其中耳穴贴压单用或联合针刺、联合穴位敷贴的不良反应发生率低于西药。结论:现有证据显示,耳穴贴压联合中药、联合穴位敷贴在提高临床有效率、改善PSQI评分方面具有较好的效果;耳穴贴压单用或联合针刺、联合穴位敷贴的不良反应发生率低于西药。但所纳入的研究方法学质量偏低,故该结论有待高质量研究予以验证。展开更多
文摘The purpose of this study was to assess factors associated with subjective sleep evaluation, chiefly excessive daytime sleepiness (EDS) in obstructive sleep apnea syndrome (OSAS) adult outpatients under continuous positive airway pressure (CPAP) treatment. One thousand and forty-eight OSAS outpatients (mean age: 51.4% male: 90.5%) who were treated by CPAP were consecutively collected. Age, sex, CPAP compliance (CPAP usage as their device of nights with application-time of at least 4 hours per night objectively;%usage ≥ 4 h/d), and Japanese version of the Pittsburgh Sleep Quality Index (PSQI-J) of the patients showing EDS (Japanese version of the Epworth Sleepiness Scale;JESS ≥ 11) were compared cross-sectionally with those of the patients who did not show EDS (JESS < 11). Nineteen point two % of all patients showed EDS subjectively. Two hundred one patients were classified to an EDS(+) group and an 847 patients were classified to EDS(–) group. Age and global PSQI-J scores were significantly different between the two groups. Logistic regression showed that EDS was significantly associated with global PSQI-J scores, but not with age. Among PSQI-J components, overall sleep quality, duration of sleep, sleep disturbance, and day dysfunction due to sleepiness were significantly higher in the EDS(+) group. Especially, 19.4% of patient in the EDS(+) group reported actual sleep time during the past month to be less than 5 hours/day. Although functional relationship should be further evaluated, insufficient sleep is the main factor associated with EDS in the OSAS patients under CPAP treatment.
