Background:Patients with colon cancer who receive chemotherapy usually experience various gastrointestinal adverse reactions,including nausea,vomiting,and diarrhea,which make it challenging for them to adhere to treat...Background:Patients with colon cancer who receive chemotherapy usually experience various gastrointestinal adverse reactions,including nausea,vomiting,and diarrhea,which make it challenging for them to adhere to treatment.As an effective traditional Chinese medicine,the Jianpi Bushen formula has been widely used to alleviate the side effects of chemotherapy.Objective:To evaluate the efficacy and safety of Jianpi Bushen formulae for patients who undergo chemotherapy.This statistical analysis plan(SAP)is intended to enhance the transparency and research quality of our randomized controlled trial.Methods:Our study is a multicenter,double-blind,randomized controlled clinical trial.This trial aimed to compare the completion rate of chemotherapy in colon cancer patients who are using and not using Jianpi Bushen formula.To attenuate possible selection bias in the final report,we declared the overall trial design,outcome measures,subgroup analyses,and safety measures.Also,we described the data management and statistical analysis methods in detail.Conclusion:The SAP provides more detailed information than the trial protocol for data management and statistical analysis methods.Further post-hoc analyses can be performed by referring to the SAP,and possible selection bias can be attenuated.展开更多
With the assistance of the identified/associated sources in the second Fermi Large Area Telescope （LAT） catalog, we analyze and resolve the spatial distribution and the distributions of the gamma-ray spectral and va...With the assistance of the identified/associated sources in the second Fermi Large Area Telescope （LAT） catalog, we analyze and resolve the spatial distribution and the distributions of the gamma-ray spectral and variability indices of the remaining 575 unassociated Fermi LAT sources. Consequently, it is suggested that the unassociated sources could statistically consist of Galactic supernova remnants/pulsar wind nebulae, BL Lacertae objects, fiat spectrum radio quasars and other types of active galaxies with fractions of 25%, 29%, 41% and 5%, respectively.展开更多
Paths planning of Unmanned Aerial Vehicles(UAVs)in a dynamic environment is considered a challenging task in autonomous flight control design.In this work,an efficient method based on a Multi-Objective MultiVerse Opti...Paths planning of Unmanned Aerial Vehicles(UAVs)in a dynamic environment is considered a challenging task in autonomous flight control design.In this work,an efficient method based on a Multi-Objective MultiVerse Optimization(MOMVO)algorithm is proposed and successfully applied to solve the path planning problem of quadrotors with moving obstacles.Such a path planning task is formulated as a multicriteria optimization problem under operational constraints.The proposed MOMVO-based planning approach aims to lead the drone to traverse the shortest path from the starting point and the target without collision with moving obstacles.The vehicle moves to the next position from its current one such that the line joining minimizes the total path length and allows aligning its direction towards the goal.To choose the best compromise solution among all the non-dominated Pareto ones obtained for compromise objectives,the modified Technique for Order Preference by Similarity to Ideal Solution(TOPSIS)is investigated.A set of homologous metaheuristics such as Multiobjective Salp Swarm Algorithm(MSSA),Multi-Objective Grey Wolf Optimizer(MOGWO),Multi-Objective Particle Swarm Optimization(MOPSO),and Non-Dominated Genetic Algorithm II(NSGAII)is used as a basis for the performance comparison.Demonstrative results and statistical analyses show the superiority and effectiveness of the proposed MOMVO-based planning method.The obtained results are satisfactory and encouraging for future practical implementation of the path planning strategy.展开更多
This paper investigates the motion planning of redundant free-floating manipulators with seven prismatic joints. On the earth, prismatic-jointed manipulators could only position their end-effectors in a desired way. H...This paper investigates the motion planning of redundant free-floating manipulators with seven prismatic joints. On the earth, prismatic-jointed manipulators could only position their end-effectors in a desired way. However, in space, the end-effectors of free-floating manipulators can achieve both the desired orientation and desired position due to the dynamical coupling between manipulator and satellite movement, which is formally expressed by linear and angular momentum conservation laws. In this study, a tractable algorithm particle swarm optimization combined with differential evolution （PSODE） is provided to deal with the motion planning of redundant free-floating prismatic-jointed manipulators, which could avoid the pseudo inverse of the Jacobian matrix. The polynomial functions, as argument in sine functions are used to specify the joint paths. The co- efficients of the polynomials are optimized to achieve the desired end-effector orientation and position, and simulta- neously minimize the unit-mass-kinetic energy using the redundancy. Relevant simulations prove that this method pro- vides satisfactory smooth paths for redundant free-floating prismatic-jointed manipulators. This study could help to recognize the advantages of redundant prismatic-jointed space manipulators.展开更多
In this paper we extend the concept of Sλ^L（I）- asymptotically statistical equivalence which is a natural combination of λ - statistical convergence and asymptotically I -equivalence. We use the sequence P = （Pk...In this paper we extend the concept of Sλ^L（I）- asymptotically statistical equivalence which is a natural combination of λ - statistical convergence and asymptotically I -equivalence. We use the sequence P = （Pk） which is the sequence of positive real numbers.展开更多
We have collected nearly all the available observed data of the elements from Ba to Dy in halo and disk stars in the metallicity range -4.0 <[Fe/H]< 0.5. Based on the observed data of Ba and Eu, we evaluated the...We have collected nearly all the available observed data of the elements from Ba to Dy in halo and disk stars in the metallicity range -4.0 <[Fe/H]< 0.5. Based on the observed data of Ba and Eu, we evaluated the least-squares regressions of [Ba/Fe] on [Fe/H], and [Eu/H] on [Ba/H]. Assuming that the heavy elements (heavier than Ba) are produced by a combination of the main components of s- and r-processes in metal-poor stars, and choosing Ba and Eu as respective representative elements of the main s- and the main r-processes, a statistical model for predicting the Galactic chemical evolution of the heavy elements is presented. With this model, we calculate the mean abundance trends of the heavy elements La, Ce, Pr, Nd, Sm, and Dy with the metallicity. We compare our results with the observed data at various metallicities, showing that the predicted trends are in good agreement with the observed trends, at least for the metallicity range [Fe/H]≥ -2.5. Finally, we discuss our results and deduce some important information about the Galactic chemical evolution.展开更多
Despite the great progress of rural socioeconomic development in the 11 th Five-year Plan period （2006-2010）, China＇s agriculture and countryside are still.lacing the challenges of a crude development pattern, back...Despite the great progress of rural socioeconomic development in the 11 th Five-year Plan period （2006-2010）, China＇s agriculture and countryside are still.lacing the challenges of a crude development pattern, backward rural development and cities＇ weak driving effect on the countryside. In the 12th Five-year Plan period （20I 1-2015）, China should transform the way agriculture grows and operates; promote rural socioeconomic development; improve urban planning and its functions, institutional innovation, and urban/rural integration to lay a solid foundation for building an all-round well- off society.展开更多
The inspection and quarantine standard is one of important basics to executeinspection and quarantine by laws. In recent years, with the development of economy and trade inChina, standardization has played an importan...The inspection and quarantine standard is one of important basics to executeinspection and quarantine by laws. In recent years, with the development of economy and trade inChina, standardization has played an important role in inspection and quarantine. During 2002-2004,department of Standards of Inspection and Quarantine, Certification and Accreditation Administrationof China has organized the research of the standards of inspection and quarantine, and has builtstandard sub- systems of nine fields in inspection and quarantine.展开更多
According to the prime task of ''readjusting industrial structure,energetically developing service industry, completing service standards and promoting servicelevel'', which are raised in the 10th Five...According to the prime task of ''readjusting industrial structure,energetically developing service industry, completing service standards and promoting servicelevel'', which are raised in the 10th Five-Year Plan Outline of National Economy and SocialDevelopment, Standardization Administration of China (SAC), National Development and ReformCommission, Ministry of Civil Affairs of the People'' s Republic of China, Ministry of Constructionof P.R.C, Ministry of Commerce of the People''s Republic of China, Ministry of Culture of the People''s Republic of China, the People''s Bank of China, General Administration of Quality Supervision,Inspection and Quarantine of P.R.C (AQSIQ), the State Administration of Radio, Film and Television,State General Administration of Sport, National Tourism Administration, China Seismological Bureau,China Meteorological Administration, China Insurance Regulatory Commission, State Post Bureau, StateCultural Relics, State Administration of Traditional Chinese Medicine Bureau, China NationalTechnical Committee 264 on Service of Standardization Administration of China, China Consumers''Association and China National Institute of Standardization had compiled and officially ratified theDevelopment Planning of National Service Standard 2005-2008 by the end of 2005.展开更多
基金funded by the Key R&D project of the Ministry of Science and Technology,China(2017YFC1700604).
文摘Background:Patients with colon cancer who receive chemotherapy usually experience various gastrointestinal adverse reactions,including nausea,vomiting,and diarrhea,which make it challenging for them to adhere to treatment.As an effective traditional Chinese medicine,the Jianpi Bushen formula has been widely used to alleviate the side effects of chemotherapy.Objective:To evaluate the efficacy and safety of Jianpi Bushen formulae for patients who undergo chemotherapy.This statistical analysis plan(SAP)is intended to enhance the transparency and research quality of our randomized controlled trial.Methods:Our study is a multicenter,double-blind,randomized controlled clinical trial.This trial aimed to compare the completion rate of chemotherapy in colon cancer patients who are using and not using Jianpi Bushen formula.To attenuate possible selection bias in the final report,we declared the overall trial design,outcome measures,subgroup analyses,and safety measures.Also,we described the data management and statistical analysis methods in detail.Conclusion:The SAP provides more detailed information than the trial protocol for data management and statistical analysis methods.Further post-hoc analyses can be performed by referring to the SAP,and possible selection bias can be attenuated.
基金supported by the National Natural Science Foundation of China (Grant No. 11103004)the Foundation for the Authors of National Excellent Doctoral Dissertations of China (Grant No. 201225)
文摘With the assistance of the identified/associated sources in the second Fermi Large Area Telescope （LAT） catalog, we analyze and resolve the spatial distribution and the distributions of the gamma-ray spectral and variability indices of the remaining 575 unassociated Fermi LAT sources. Consequently, it is suggested that the unassociated sources could statistically consist of Galactic supernova remnants/pulsar wind nebulae, BL Lacertae objects, fiat spectrum radio quasars and other types of active galaxies with fractions of 25%, 29%, 41% and 5%, respectively.
文摘Paths planning of Unmanned Aerial Vehicles(UAVs)in a dynamic environment is considered a challenging task in autonomous flight control design.In this work,an efficient method based on a Multi-Objective MultiVerse Optimization(MOMVO)algorithm is proposed and successfully applied to solve the path planning problem of quadrotors with moving obstacles.Such a path planning task is formulated as a multicriteria optimization problem under operational constraints.The proposed MOMVO-based planning approach aims to lead the drone to traverse the shortest path from the starting point and the target without collision with moving obstacles.The vehicle moves to the next position from its current one such that the line joining minimizes the total path length and allows aligning its direction towards the goal.To choose the best compromise solution among all the non-dominated Pareto ones obtained for compromise objectives,the modified Technique for Order Preference by Similarity to Ideal Solution(TOPSIS)is investigated.A set of homologous metaheuristics such as Multiobjective Salp Swarm Algorithm(MSSA),Multi-Objective Grey Wolf Optimizer(MOGWO),Multi-Objective Particle Swarm Optimization(MOPSO),and Non-Dominated Genetic Algorithm II(NSGAII)is used as a basis for the performance comparison.Demonstrative results and statistical analyses show the superiority and effectiveness of the proposed MOMVO-based planning method.The obtained results are satisfactory and encouraging for future practical implementation of the path planning strategy.
基金supported by the National Natural Science Foundation of China (11072122)
文摘This paper investigates the motion planning of redundant free-floating manipulators with seven prismatic joints. On the earth, prismatic-jointed manipulators could only position their end-effectors in a desired way. However, in space, the end-effectors of free-floating manipulators can achieve both the desired orientation and desired position due to the dynamical coupling between manipulator and satellite movement, which is formally expressed by linear and angular momentum conservation laws. In this study, a tractable algorithm particle swarm optimization combined with differential evolution （PSODE） is provided to deal with the motion planning of redundant free-floating prismatic-jointed manipulators, which could avoid the pseudo inverse of the Jacobian matrix. The polynomial functions, as argument in sine functions are used to specify the joint paths. The co- efficients of the polynomials are optimized to achieve the desired end-effector orientation and position, and simulta- neously minimize the unit-mass-kinetic energy using the redundancy. Relevant simulations prove that this method pro- vides satisfactory smooth paths for redundant free-floating prismatic-jointed manipulators. This study could help to recognize the advantages of redundant prismatic-jointed space manipulators.
文摘In this paper we extend the concept of Sλ^L（I）- asymptotically statistical equivalence which is a natural combination of λ - statistical convergence and asymptotically I -equivalence. We use the sequence P = （Pk） which is the sequence of positive real numbers.
基金This research has been supported by the National Natural Science Foundation of China through grant No.19973002 Chinese Academy of Sciences-Peking University Joint Beijing Astrophysical Center.
文摘We have collected nearly all the available observed data of the elements from Ba to Dy in halo and disk stars in the metallicity range -4.0 <[Fe/H]< 0.5. Based on the observed data of Ba and Eu, we evaluated the least-squares regressions of [Ba/Fe] on [Fe/H], and [Eu/H] on [Ba/H]. Assuming that the heavy elements (heavier than Ba) are produced by a combination of the main components of s- and r-processes in metal-poor stars, and choosing Ba and Eu as respective representative elements of the main s- and the main r-processes, a statistical model for predicting the Galactic chemical evolution of the heavy elements is presented. With this model, we calculate the mean abundance trends of the heavy elements La, Ce, Pr, Nd, Sm, and Dy with the metallicity. We compare our results with the observed data at various metallicities, showing that the predicted trends are in good agreement with the observed trends, at least for the metallicity range [Fe/H]≥ -2.5. Finally, we discuss our results and deduce some important information about the Galactic chemical evolution.
文摘Despite the great progress of rural socioeconomic development in the 11 th Five-year Plan period （2006-2010）, China＇s agriculture and countryside are still.lacing the challenges of a crude development pattern, backward rural development and cities＇ weak driving effect on the countryside. In the 12th Five-year Plan period （20I 1-2015）, China should transform the way agriculture grows and operates; promote rural socioeconomic development; improve urban planning and its functions, institutional innovation, and urban/rural integration to lay a solid foundation for building an all-round well- off society.
文摘The inspection and quarantine standard is one of important basics to executeinspection and quarantine by laws. In recent years, with the development of economy and trade inChina, standardization has played an important role in inspection and quarantine. During 2002-2004,department of Standards of Inspection and Quarantine, Certification and Accreditation Administrationof China has organized the research of the standards of inspection and quarantine, and has builtstandard sub- systems of nine fields in inspection and quarantine.
文摘According to the prime task of ''readjusting industrial structure,energetically developing service industry, completing service standards and promoting servicelevel'', which are raised in the 10th Five-Year Plan Outline of National Economy and SocialDevelopment, Standardization Administration of China (SAC), National Development and ReformCommission, Ministry of Civil Affairs of the People'' s Republic of China, Ministry of Constructionof P.R.C, Ministry of Commerce of the People''s Republic of China, Ministry of Culture of the People''s Republic of China, the People''s Bank of China, General Administration of Quality Supervision,Inspection and Quarantine of P.R.C (AQSIQ), the State Administration of Radio, Film and Television,State General Administration of Sport, National Tourism Administration, China Seismological Bureau,China Meteorological Administration, China Insurance Regulatory Commission, State Post Bureau, StateCultural Relics, State Administration of Traditional Chinese Medicine Bureau, China NationalTechnical Committee 264 on Service of Standardization Administration of China, China Consumers''Association and China National Institute of Standardization had compiled and officially ratified theDevelopment Planning of National Service Standard 2005-2008 by the end of 2005.
