In Northeast China,Goubao pickle is a popular food fermented from the roots of Platycodon grandiflorum as the main material,offering a unique flavor and rich nutritional value.Platycosides in roots of P.grandiflorum m...In Northeast China,Goubao pickle is a popular food fermented from the roots of Platycodon grandiflorum as the main material,offering a unique flavor and rich nutritional value.Platycosides in roots of P.grandiflorum may play a crucial role in determining the quality of Goubao pickle through microorganism fermentation.However,biotransfermation of platycosides has not been reviewed during fermentation.In this study,we reviewed platycosides in chemical diversity,metabolic processes in vivo,biotransformation of platycosides in vitro,and pharmacological effects.Finally,we also discussed how to improve the bioactive secondary platycosides we desire by regulating enzymes from microorganisms in the future.展开更多
Platycodonis Radix(Jiegeng in Chinese)is a well-known traditional Chinese medicine used for both medicinal and culinary purposes.Its historical use as an antitussive and expectorant has been extensively documented.Res...Platycodonis Radix(Jiegeng in Chinese)is a well-known traditional Chinese medicine used for both medicinal and culinary purposes.Its historical use as an antitussive and expectorant has been extensively documented.Researchers,to date,have identified 219 chemical constituents in Platycodon grandiflorum(Jacq.)A.DC,encompassing 89 saponins,11 flavonoids,21 polysaccharides,14 phenolic acids,six polyacetylenes,five sterols,34 fatty acids,17 amino acids,and 22 trace elements.Jiegeng exhibits diverse pharmacological effects,including antitussive and anti-phlegm properties,anti-cancer activity,anti-inflammatory effects,immune regulation,antioxidant properties,anti-obesity,and antidiabetic effects.Additionally,Jiegeng shows potential in protecting the heart and liver.Beyond its medicinal benefits,Jiegeng is highly esteemed in culinary applications,and its global demand is on the rise.Its utilization has expanded beyond medicine and food to encompass daily necessities,cosmetics,agricultural supplies,and other fields.Currently,there are 18272 patents related to P.grandiflorum.This comprehensive review summarizes the latest research published over the past 20 years,providing a robust foundation for further exploration of the medicinal and health benefits of P.grandiflorum.展开更多
A Study of tissue culture in vitro and plant reproduction of Platycodon grandiflorum A. DC. was carried out. The results indicated that MS medium containing 6\|BA 1.0 mg/L and IAA 0.5 mg/L was the best for callus indu...A Study of tissue culture in vitro and plant reproduction of Platycodon grandiflorum A. DC. was carried out. The results indicated that MS medium containing 6\|BA 1.0 mg/L and IAA 0.5 mg/L was the best for callus induction; MS medium containing 6\|BA 0.3 mg/L and IAA 0.1 mg/L was suitable for crowd bud propagation; 1/2 MS medium containing IAA 0.5 mg/L and ABT 0.1 mg/L is effective in inducing root with the ratio of 95%, fast propagation of P. grandiflorum by tissue culture method could be established, which will lay down the foundation of the breeding and clone of excellent varieties of P. grandiflorum.展开更多
基金supported by the National Natural Science Foundation of China(No.U20A20400)the Scientific Research Foundation of Heilongjiang Provincial Scientific Research Institutes(No.CZKYF2021A002)Young and middle-aged graduate tutor training program of Shenyang Agricultural University(No.2022-ZZDS-09).
文摘In Northeast China,Goubao pickle is a popular food fermented from the roots of Platycodon grandiflorum as the main material,offering a unique flavor and rich nutritional value.Platycosides in roots of P.grandiflorum may play a crucial role in determining the quality of Goubao pickle through microorganism fermentation.However,biotransfermation of platycosides has not been reviewed during fermentation.In this study,we reviewed platycosides in chemical diversity,metabolic processes in vivo,biotransformation of platycosides in vitro,and pharmacological effects.Finally,we also discussed how to improve the bioactive secondary platycosides we desire by regulating enzymes from microorganisms in the future.
基金supported by the National Key Research and Development Program of China(No.2022YFC3501805)for financial support.
文摘Platycodonis Radix(Jiegeng in Chinese)is a well-known traditional Chinese medicine used for both medicinal and culinary purposes.Its historical use as an antitussive and expectorant has been extensively documented.Researchers,to date,have identified 219 chemical constituents in Platycodon grandiflorum(Jacq.)A.DC,encompassing 89 saponins,11 flavonoids,21 polysaccharides,14 phenolic acids,six polyacetylenes,five sterols,34 fatty acids,17 amino acids,and 22 trace elements.Jiegeng exhibits diverse pharmacological effects,including antitussive and anti-phlegm properties,anti-cancer activity,anti-inflammatory effects,immune regulation,antioxidant properties,anti-obesity,and antidiabetic effects.Additionally,Jiegeng shows potential in protecting the heart and liver.Beyond its medicinal benefits,Jiegeng is highly esteemed in culinary applications,and its global demand is on the rise.Its utilization has expanded beyond medicine and food to encompass daily necessities,cosmetics,agricultural supplies,and other fields.Currently,there are 18272 patents related to P.grandiflorum.This comprehensive review summarizes the latest research published over the past 20 years,providing a robust foundation for further exploration of the medicinal and health benefits of P.grandiflorum.
文摘A Study of tissue culture in vitro and plant reproduction of Platycodon grandiflorum A. DC. was carried out. The results indicated that MS medium containing 6\|BA 1.0 mg/L and IAA 0.5 mg/L was the best for callus induction; MS medium containing 6\|BA 0.3 mg/L and IAA 0.1 mg/L was suitable for crowd bud propagation; 1/2 MS medium containing IAA 0.5 mg/L and ABT 0.1 mg/L is effective in inducing root with the ratio of 95%, fast propagation of P. grandiflorum by tissue culture method could be established, which will lay down the foundation of the breeding and clone of excellent varieties of P. grandiflorum.
