The aim of this study was to determine whether the lower urinary tract storage symptoms of benign prostatic obstruction (BPO) could be completely resolved after plasmakinetic enucleation of the prostate (PKEP) and...The aim of this study was to determine whether the lower urinary tract storage symptoms of benign prostatic obstruction (BPO) could be completely resolved after plasmakinetic enucleation of the prostate (PKEP) and the possible predictors of persistent symptoms. Two hundred and sixty-seven cases of BPO performed PKEP from July 2008 to June 2009 were retrospectively analyzed. Five-year postoperative data were collected and compared with the preoperative data. According to the urodynamic results, the patients were divided into involuntary detrusor contraction (IDC) group (n = 95) and no IDC group (n = 172) preoperatively; the patients with IDC were divided into IDC-persistent group (n = 33) and IDC-resolved group (n = 62) after PKER The predictors of persistent IDC were analyzed. Compared with the preoperative data, the 5-year postoperative data showed that the IDC rate was lower (P --- 0.000), Overactive Bladder Symptom Score (OABSS) was lower (P = 0.000), maximum cystometric capacity (MCC) was larger (P= 0.000), Prostate volume (PV) was smaller (P= 0.000), and prostate-specific antigen (PSA) was lower (P= 0.000). Compared with the no IDC group, the IDC group showed that the age was older (P = 0.016), MCC was smaller (P = 0.004), PSA was higher (P = 0.016), and Chronic Inflammation rate was higher (P = 0.004). Compared with IDC-resolved group after PKER IDC-persistent group showed that the age was older (P = 0.019), MCC was smaller (P = 0.000), PSA was higher (P = 0.013), and Chronic Ihflammation rate was higher (P = 0.032). The present study shows that the storage symptoms are still needed to be focused on after PKER The advanced patient age, MCC, PSA, and chronic inflammation may be the important clinical predictors of persistent IDC.展开更多
目的比较分析经尿道等离子前列腺剜除术(transurethral plasmakinetic enucleation of prostate,TUPKEP)与经尿道前列腺电切术(transurethral resection of prostate,TURP)治疗良性前列腺增生的疗效和安全性。方法随机选取2012年4月至2...目的比较分析经尿道等离子前列腺剜除术(transurethral plasmakinetic enucleation of prostate,TUPKEP)与经尿道前列腺电切术(transurethral resection of prostate,TURP)治疗良性前列腺增生的疗效和安全性。方法随机选取2012年4月至2017年10月成都市双流区第一人民医院外科诊治的200名患者为研究对象,依据治疗方法将其分为TUPKEP组和TURP组,每组100名患者。TUPKEP组患者接受TUPKEP治疗,TURP组患者接受TURP治疗,对两组患者的术中术后指标、Qmax、PRV、IPSS评分、QOL评分、术后并发症发生情况等进行统计分析。结果 TUPKEP组患者的术中出血量显著少于TURP组患者(P<0.05),前列腺切除重量显著高于TURP组患者(P<0.05),手术时间、术后膀胱冲洗时间均显著短于TURP组(均P<0.05),术后并发症的发生率(2.0%,2/100)显著低于TURP组患者(24.0%,24/100)(P<0.05),但两组患者手术前后的Qmax、PRV、IPSS评分、QOL评分之间的差异均无统计学意义(均P>0.05)。结论 TUPKEP治疗良性前列腺增生的疗效和安全性高于TURP,值得在临床推广应用。展开更多
文摘The aim of this study was to determine whether the lower urinary tract storage symptoms of benign prostatic obstruction (BPO) could be completely resolved after plasmakinetic enucleation of the prostate (PKEP) and the possible predictors of persistent symptoms. Two hundred and sixty-seven cases of BPO performed PKEP from July 2008 to June 2009 were retrospectively analyzed. Five-year postoperative data were collected and compared with the preoperative data. According to the urodynamic results, the patients were divided into involuntary detrusor contraction (IDC) group (n = 95) and no IDC group (n = 172) preoperatively; the patients with IDC were divided into IDC-persistent group (n = 33) and IDC-resolved group (n = 62) after PKER The predictors of persistent IDC were analyzed. Compared with the preoperative data, the 5-year postoperative data showed that the IDC rate was lower (P --- 0.000), Overactive Bladder Symptom Score (OABSS) was lower (P = 0.000), maximum cystometric capacity (MCC) was larger (P= 0.000), Prostate volume (PV) was smaller (P= 0.000), and prostate-specific antigen (PSA) was lower (P= 0.000). Compared with the no IDC group, the IDC group showed that the age was older (P = 0.016), MCC was smaller (P = 0.004), PSA was higher (P = 0.016), and Chronic Inflammation rate was higher (P = 0.004). Compared with IDC-resolved group after PKER IDC-persistent group showed that the age was older (P = 0.019), MCC was smaller (P = 0.000), PSA was higher (P = 0.013), and Chronic Ihflammation rate was higher (P = 0.032). The present study shows that the storage symptoms are still needed to be focused on after PKER The advanced patient age, MCC, PSA, and chronic inflammation may be the important clinical predictors of persistent IDC.
文摘目的比较分析经尿道等离子前列腺剜除术(transurethral plasmakinetic enucleation of prostate,TUPKEP)与经尿道前列腺电切术(transurethral resection of prostate,TURP)治疗良性前列腺增生的疗效和安全性。方法随机选取2012年4月至2017年10月成都市双流区第一人民医院外科诊治的200名患者为研究对象,依据治疗方法将其分为TUPKEP组和TURP组,每组100名患者。TUPKEP组患者接受TUPKEP治疗,TURP组患者接受TURP治疗,对两组患者的术中术后指标、Qmax、PRV、IPSS评分、QOL评分、术后并发症发生情况等进行统计分析。结果 TUPKEP组患者的术中出血量显著少于TURP组患者(P<0.05),前列腺切除重量显著高于TURP组患者(P<0.05),手术时间、术后膀胱冲洗时间均显著短于TURP组(均P<0.05),术后并发症的发生率(2.0%,2/100)显著低于TURP组患者(24.0%,24/100)(P<0.05),但两组患者手术前后的Qmax、PRV、IPSS评分、QOL评分之间的差异均无统计学意义(均P>0.05)。结论 TUPKEP治疗良性前列腺增生的疗效和安全性高于TURP,值得在临床推广应用。