The action of needling in acupoint therapy has to first be regulated and integrated by the brain, and then it affects the target organ and manifests its therapeutic effects, which is dependent on the specificity of th...The action of needling in acupoint therapy has to first be regulated and integrated by the brain, and then it affects the target organ and manifests its therapeutic effects, which is dependent on the specificity of the acupoints. The authors put forward the hypothesis of the ＂acupoint-related brain＂. Single-photon emission computed tomography was used to explore the activation of brain regions following true needling in true acupoint Waiguan （SJ 5）, sham needling in true acupoint Waiguan, true needling in a sham point, and sham needling in a sham point. The relative specificity of Waiguan in normal persons was analyzed by observing changes in regional cerebral blood flow. Compared with the sham needling in true acupoint group and sham needling in the sham point group, acupuncture at Waiguan can activate brain regions controlling movement. Compared with true needling in the sham point group, acupuncture at Waiguan can also activate brain regions controlling movement. The results suggest that the specificity of needling at an acupoint is related to certain activated cerebral functional regions, which are associated with the clinical application of the acupoint.展开更多
In the present study, 10 patients with ischemic stroke in the left hemisphere and six healthy controls were subjected to acupuncture at right Waiguan （TE5）. In ischemic stroke subjects, functional MRI showed enhance...In the present study, 10 patients with ischemic stroke in the left hemisphere and six healthy controls were subjected to acupuncture at right Waiguan （TE5）. In ischemic stroke subjects, functional MRI showed enhanced activation in Broadmann areas 5, 6, 7, 18, 19, 24, 32, the hypothalamic inferior lobe, the mamiilary body, and the ventral posterolateral nucleus of the left hemisphere, and Broadmann areas 4, 6, 7, 18, 19 and 32 of the right hemisphere, but attenuated activation of Broadmann area 13, the hypothalamic inferior lobe, the posterior lobe of the tonsil of cerebellum, and the culmen of the anterior lobe of hypophysis, in the left hemisphere and Broadmann area 13 in the right hemisphere. In ischemic stroke subjects, a number of deactivated brain areas were enhanced, including Broadmann areas 6, 11,20, 22, 37, and 47, the culmen of the anterior lobe of hypophysis, alae lingulae cerebella, and the posterior lobe of the tonsil of cerebellum of the left hemisphere, and Broadmann areas 8, 37, 45 and 47, the culmen of the anterior lobe of hypophysis, pars tuberalis adenohypophyseos, inferior border of lentiform nucleus, lateral globus pallidus, inferior temporal gyrus, and the parahippocampal gyrus of the right hemisphere. These subjects also exhibited attenuation of a number of deactivated brain areas, including Broadmann area 7. These data suggest that acupuncture at Waiguan specifically alters brain function in regions associated with sensation, vision, and motion in ischemic stroke patients. By contrast, in normal individuals, acupuncture at Waiguan generally activates brain areas associated with insomnia and other functions.展开更多
We compared the activities of functional regions of the brain in the Deqi versus non-Deqi state, as reported by physicians and subjects cludng acupuncture, Twelve healthy volunteers received sham and true needling at ...We compared the activities of functional regions of the brain in the Deqi versus non-Deqi state, as reported by physicians and subjects cludng acupuncture, Twelve healthy volunteers received sham and true needling at the Waiguan （TE5） acupoint. Real-time cerebral functional MRI showed that compared with non-sensation after sham needling, true needling activated Brodmann areas 3, 6, 8, 9, 10, 11, 13, 20, 21, 37, 39, 40, 43, and 47, the head of the caudate nucleus, the parahippocampal gyrus, thalamus and red nucleus. True needling also deactivated Brodmann areas 1,2, 3, 4, 5, 6, 7, 9. 10. 18.24.31.40 and 46.展开更多
Objective To observe the therapeutic effects of post-stroke hand motor impairment treated with acupuncture at Zhongzhu （中渚 TE 3） and Waiguan （外关TE 5）. Methods Sixty cases of post-stroke hand motor impairment w...Objective To observe the therapeutic effects of post-stroke hand motor impairment treated with acupuncture at Zhongzhu （中渚 TE 3） and Waiguan （外关TE 5）. Methods Sixty cases of post-stroke hand motor impairment were randomly divided into an observation group and a control group, 30 cases in each one. The conventional medication, physical therapy, occupational therapy and other rehabilitation trainings were applied in both groups. In observation group, Zhongzhu （中渚 TE 3） and Waiguan （外关TE 5） were punctured. The assessment was performed with neurologie deficit scoring of the National Institutes of Health Stroke Scale （NIHSS）, hand motor function, walking ability and the modified Barthel index scale of the Activities of Daily Living （ADL） in both groups before and after treatment. Results After treatment, the scores of hand function, walking ability, ADL and NIHSS were improved in both groups as compared with those before treatment （all P〈0.01）. The improvements of hand function, walking ability and ADL ：in observation group were superior to those in control group （all P〈0.05）. Conclusion The conventional medication and rehabilitation trainings combined with acupuncture at Zhongzhu （中渚 TE 3） and Waiguan （外关TE 5） ean obviously improve hand motor function, walking ability, the activities of daily living and rehabilitation efficacy in the patients with post-stroke hand motor impairment.展开更多
Based on the neutron and proton degrees of freedom, low-lying energy levels, E2, M1, and E0 transition strengths of nucleus ^(124)Te have been calculated by the neutron-proton interacting boson model. The calculated r...Based on the neutron and proton degrees of freedom, low-lying energy levels, E2, M1, and E0 transition strengths of nucleus ^(124)Te have been calculated by the neutron-proton interacting boson model. The calculated results are reasonably consistent with the experimental data. By comparing the key observables of the states at the critical point of U_(πv)(5)-O_(πv)(6) transition with the experimental data and calculated results, we show that the ^(124)Te is a possible nucleus at the critical point of the second-order phase transition from vibration to unstable rotation, and such a critical point exhibits slight triaxial rotation. The 0_2^+ state of ^(124)Te can be interpreted as the lowest state of the first-excited family of the intrinsic levels in the critical point symmetry.展开更多
Objective To observe the comparison of the clinical efficacy between penetration needling from Neiguan （内关 PC 6） to Waiguan （外关 TE 5） and western medicine estazolam for insomnia. Methods Sixty insomnia patient...Objective To observe the comparison of the clinical efficacy between penetration needling from Neiguan （内关 PC 6） to Waiguan （外关 TE 5） and western medicine estazolam for insomnia. Methods Sixty insomnia patients were divided into 2 groups according to the random number table, 30 cases in each group. Penetration needling from PC 6 to TE 5 was mainly adopted in acupuncture group for once a day, 5timesa week, and treatment for 4 weeks was 1 course of treatment. Estazolam was orally given in medicine group before sleep every night in a dosage of 1 mg per time, and treatment for 4 weeks was 2 course of treatment. After 4 weeks, the clinical efficacy and the Pittsburgh Sleep Quality Index （PSQI） score were compared respectively between the two groups. Results The total effective rate was 90.00% in acupuncture group and 63.33% in medicine group, and the difference was statistically significant （P〈0.05）. PSQI score in acupuncture group was （7.93＋3.77）, which was superior to that in medicine group （10.60＋4.20）, and the difference between the two groups was statistically significant （P〈0.05）. Conclusion The penetration needling of complementary acupoints from PC 6 to TE 5 was simple and convenient which can significantly improve the patients＇ sleep quality.展开更多
基金supported by the National 973 Program of China,No.2006CB504505the National Natural Science Foundation of China,No.90709027
文摘The action of needling in acupoint therapy has to first be regulated and integrated by the brain, and then it affects the target organ and manifests its therapeutic effects, which is dependent on the specificity of the acupoints. The authors put forward the hypothesis of the ＂acupoint-related brain＂. Single-photon emission computed tomography was used to explore the activation of brain regions following true needling in true acupoint Waiguan （SJ 5）, sham needling in true acupoint Waiguan, true needling in a sham point, and sham needling in a sham point. The relative specificity of Waiguan in normal persons was analyzed by observing changes in regional cerebral blood flow. Compared with the sham needling in true acupoint group and sham needling in the sham point group, acupuncture at Waiguan can activate brain regions controlling movement. Compared with true needling in the sham point group, acupuncture at Waiguan can also activate brain regions controlling movement. The results suggest that the specificity of needling at an acupoint is related to certain activated cerebral functional regions, which are associated with the clinical application of the acupoint.
基金supported by the National Basic Research Program of China(973 Program),No.2006CB504505,2012CB518504the Third Key Construction Program of "211 Project" of Guangdong Province
文摘In the present study, 10 patients with ischemic stroke in the left hemisphere and six healthy controls were subjected to acupuncture at right Waiguan （TE5）. In ischemic stroke subjects, functional MRI showed enhanced activation in Broadmann areas 5, 6, 7, 18, 19, 24, 32, the hypothalamic inferior lobe, the mamiilary body, and the ventral posterolateral nucleus of the left hemisphere, and Broadmann areas 4, 6, 7, 18, 19 and 32 of the right hemisphere, but attenuated activation of Broadmann area 13, the hypothalamic inferior lobe, the posterior lobe of the tonsil of cerebellum, and the culmen of the anterior lobe of hypophysis, in the left hemisphere and Broadmann area 13 in the right hemisphere. In ischemic stroke subjects, a number of deactivated brain areas were enhanced, including Broadmann areas 6, 11,20, 22, 37, and 47, the culmen of the anterior lobe of hypophysis, alae lingulae cerebella, and the posterior lobe of the tonsil of cerebellum of the left hemisphere, and Broadmann areas 8, 37, 45 and 47, the culmen of the anterior lobe of hypophysis, pars tuberalis adenohypophyseos, inferior border of lentiform nucleus, lateral globus pallidus, inferior temporal gyrus, and the parahippocampal gyrus of the right hemisphere. These subjects also exhibited attenuation of a number of deactivated brain areas, including Broadmann area 7. These data suggest that acupuncture at Waiguan specifically alters brain function in regions associated with sensation, vision, and motion in ischemic stroke patients. By contrast, in normal individuals, acupuncture at Waiguan generally activates brain areas associated with insomnia and other functions.
基金supported by the National Basic Research Program of China (973 Program), No. 2006CB504505,2012CB518504the Third Key Construction Program of"211 Project" of Guangdong Province
文摘We compared the activities of functional regions of the brain in the Deqi versus non-Deqi state, as reported by physicians and subjects cludng acupuncture, Twelve healthy volunteers received sham and true needling at the Waiguan （TE5） acupoint. Real-time cerebral functional MRI showed that compared with non-sensation after sham needling, true needling activated Brodmann areas 3, 6, 8, 9, 10, 11, 13, 20, 21, 37, 39, 40, 43, and 47, the head of the caudate nucleus, the parahippocampal gyrus, thalamus and red nucleus. True needling also deactivated Brodmann areas 1,2, 3, 4, 5, 6, 7, 9. 10. 18.24.31.40 and 46.
文摘Objective To observe the therapeutic effects of post-stroke hand motor impairment treated with acupuncture at Zhongzhu （中渚 TE 3） and Waiguan （外关TE 5）. Methods Sixty cases of post-stroke hand motor impairment were randomly divided into an observation group and a control group, 30 cases in each one. The conventional medication, physical therapy, occupational therapy and other rehabilitation trainings were applied in both groups. In observation group, Zhongzhu （中渚 TE 3） and Waiguan （外关TE 5） were punctured. The assessment was performed with neurologie deficit scoring of the National Institutes of Health Stroke Scale （NIHSS）, hand motor function, walking ability and the modified Barthel index scale of the Activities of Daily Living （ADL） in both groups before and after treatment. Results After treatment, the scores of hand function, walking ability, ADL and NIHSS were improved in both groups as compared with those before treatment （all P〈0.01）. The improvements of hand function, walking ability and ADL ：in observation group were superior to those in control group （all P〈0.05）. Conclusion The conventional medication and rehabilitation trainings combined with acupuncture at Zhongzhu （中渚 TE 3） and Waiguan （外关TE 5） ean obviously improve hand motor function, walking ability, the activities of daily living and rehabilitation efficacy in the patients with post-stroke hand motor impairment.
基金Supported by the National Natural Science Foundation of China(11475062,11147148,11747312)
文摘Based on the neutron and proton degrees of freedom, low-lying energy levels, E2, M1, and E0 transition strengths of nucleus ^(124)Te have been calculated by the neutron-proton interacting boson model. The calculated results are reasonably consistent with the experimental data. By comparing the key observables of the states at the critical point of U_(πv)(5)-O_(πv)(6) transition with the experimental data and calculated results, we show that the ^(124)Te is a possible nucleus at the critical point of the second-order phase transition from vibration to unstable rotation, and such a critical point exhibits slight triaxial rotation. The 0_2^+ state of ^(124)Te can be interpreted as the lowest state of the first-excited family of the intrinsic levels in the critical point symmetry.
基金Supported by Hebei One Hundred Excellent Innovative Talents Supporting Plan:BR2-104
文摘Objective To observe the comparison of the clinical efficacy between penetration needling from Neiguan （内关 PC 6） to Waiguan （外关 TE 5） and western medicine estazolam for insomnia. Methods Sixty insomnia patients were divided into 2 groups according to the random number table, 30 cases in each group. Penetration needling from PC 6 to TE 5 was mainly adopted in acupuncture group for once a day, 5timesa week, and treatment for 4 weeks was 1 course of treatment. Estazolam was orally given in medicine group before sleep every night in a dosage of 1 mg per time, and treatment for 4 weeks was 2 course of treatment. After 4 weeks, the clinical efficacy and the Pittsburgh Sleep Quality Index （PSQI） score were compared respectively between the two groups. Results The total effective rate was 90.00% in acupuncture group and 63.33% in medicine group, and the difference was statistically significant （P〈0.05）. PSQI score in acupuncture group was （7.93＋3.77）, which was superior to that in medicine group （10.60＋4.20）, and the difference between the two groups was statistically significant （P〈0.05）. Conclusion The penetration needling of complementary acupoints from PC 6 to TE 5 was simple and convenient which can significantly improve the patients＇ sleep quality.
