An innovative,ternary nanocomposite composed of overoxidized poly(3,4-ethylenedioxythiophene)(OPEDOT),gold nanoparticles(Au NPs),and electrochemically reduced graphene oxide(ERGO)was prepared on a glassy carbon electr...An innovative,ternary nanocomposite composed of overoxidized poly(3,4-ethylenedioxythiophene)(OPEDOT),gold nanoparticles(Au NPs),and electrochemically reduced graphene oxide(ERGO)was prepared on a glassy carbon electrode(GCE)(OPEDOT-Au NPs-ERGO/GCE)through homogeneous chemical reactions and heterogeneous electrochemical methods.The morphology,composition,and structure of this nanocomposite were characterized by transmission electron microscopy,scanning electron microscopy,X-ray diffraction,and X-ray photoelectron spectroscopy.The electrochemical properties of the OPEDOT-Au NPs-ERGO/GCE were investigated by cyclic voltammetry using potassium ferricyanide and hexaammineruthenium(III)chloride redox probe systems.This modified electrode shows excellent electro-catalytic activity for dopamine(DA)and uric acid(UA)under physiological p H conditions,but inhibits the oxidation of ascorbic acid(AA).Linear voltammetric responses were obtained when DA concentrations of approximately 4.0-100μM and UA concentrations of approximately 20-100μM were used.The detection limits(S/N=3)for DA and UA were 1.0 and 5.0μM,respectively,under physiological conditions and in the presence of 1.0 m M of AA.This developed method was applied to the simultaneous detection of DA and UA in human urine,where satisfactory recoveries from 96.7%to 105.0%were observed.This work demonstrates that the developed OPEDOT-Au NPs-ERGO ternary nanocomposite,with its excellent ion-selectivity and electro-catalytic activity,is a promising candidate for the simultaneous detection of DA and UA in the presence of AA in physiological and pathological studies.展开更多
Poly （3, 4-ethylenedioxythiophene） （PEDOT）, together with its dopes, such as poly （styrene sulfonate） （PSS）, has been acknowledged to have a wide range of biomedical applications as an important conducting pol...Poly （3, 4-ethylenedioxythiophene） （PEDOT）, together with its dopes, such as poly （styrene sulfonate） （PSS）, has been acknowledged to have a wide range of biomedical applications as an important conducting polymer. In this study, gelatin can be polymerized into PEDOT/PSS polymers on indium tin oxide （ITO）-coated glass. PEDOT/PSS/gelatin layer on ITO-coated glass significantly decreases electrochemical impedance spectroscopy （EIS） and increases charge delivery capacity relative to the gelatin layer and bare ITO- coated glass, comparable to the PEDOT/PSS layer on ITO-coated glass. PEDOT/PSS/gelatin layer on ITO- coated glass enhances pheochromocytoma （PC 12） cell affinity, possesses a high biocompatibility and promotes PC 12 cell growth by delivery of electrical stimulation. These results suggest that gelatin can be incorporated into the PEDOT/PSS polymers through electrochemical polymerization and the PEDOT/PSS/gelatin layer on ITO-coated glass possesses high electrochemical and biological activities.展开更多
[Objective] This paper was to introduce the chemical oxidative synthesis process, properties and test methods of 3,4-ethylenedioxythiophene(EDOT). [Method] The poor water solubility of EDOT was solved by using polyeth...[Objective] This paper was to introduce the chemical oxidative synthesis process, properties and test methods of 3,4-ethylenedioxythiophene(EDOT). [Method] The poor water solubility of EDOT was solved by using polyethylene glycol 20000(PEG) as the surfactant. The monomer was polymerized by chemical oxidative synthesis. The product was analyzed and verified by infrared spectrum, X-ray diffraction, ultraviolet-visible absorption spectra.[Result] The conductivity of the product was the best when the mass ratio of PEG and EDOT was 1∶1. The effects of oxidant dose and reaction time on the conductivity and yield of the product showed certain regularity. [Conclusion] EDOT could be polymerized by PEG and FeCl3, and the polymerization product was PEDOT.展开更多
In this work,poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)(PEDOT:PSS)coated silver telluride(PCeAg2Te)nanorods were prepared by a wet-chemical method using the PEDOT:PSS coated tellurium(PCeTe)nanorods as th...In this work,poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)(PEDOT:PSS)coated silver telluride(PCeAg2Te)nanorods were prepared by a wet-chemical method using the PEDOT:PSS coated tellurium(PCeTe)nanorods as the templates.Flexible PCeAg2Te nanocomposite film on polyethersulfone(PES)substrate was prepared through vacuum filtration followed by mechanical pressing process.An optimal PCeAg2Te nanocomposite film showed a maximum power factor of 143.3 mW/mK^(2) at room temperature and 221.7 μW/mK^(2 ) at 373 K.The electrical conductivity of the PCeAg2Te composite film decreased by3.3%after bending for 1000 times around a rod with a radius of 5 mm.An eight-leg thermoelectric generator assembled with the optimal PCeAg2Te nanocomposite film generated a maximum output power and output density of 209.4 nW and 141.5 mW/cm^(2) at a temperature gradient of 30.3 K.This work provides a facile method to prepare thermoelectric materials for flexible thermoelectric generators.展开更多
Vitamin C （VC） content in commercial juices was voltammetrically determined using a highly selective and sensitive poly（3,4-ethylenedioxythiophene methanol）/ascorbate oxidase/Nafion-single-walled carbon nanotubes ...Vitamin C （VC） content in commercial juices was voltammetrically determined using a highly selective and sensitive poly（3,4-ethylenedioxythiophene methanol）/ascorbate oxidase/Nafion-single-walled carbon nanotubes （PEDOTM/AO/Nation-SWCNT） biosensor. The biocompatible PEDOTM matrix was prepared facilely by the one-step electrochemical deposition technique in lithium perehlorate aqueous solutions. AO was dip-coated on the surface of the biocompatible PEDOTM matrix. The mixture of Nafion-SWCNT was dip-cast onto the surface of AO layer when it was obtained by blending Nation solution and SWCNT dispersion together in a volume ratio of 1：1. The prepared PEDOTM/AO/Nafion-SWCNT biosensor was used for the voltammetric determination of VC, which exhibited the good linear range （4.0 ~ 10-s-3 x 10-s mol/L）, low detection limit （13 I^mol/L）, pronounced sensitivity （1.4072 mA （mmol/L） i cm 2）, high bioaftinity （low apparent Michaelis-Menten constant）, good stability （good repeatability）, high specificity （good anti-interference ability） coupled with the good reliability and feasibility （the determination of VC in commercial juices）. Meanwhile, the good aqueous solubility and the low onset oxidation potential of EDOTM will be more beneficial to the application in biosensor field compared to 3,4-ethylenedioxythiophene. Moreover, the good biocompatibility of PEDOTM matrix and high selectivity of Nation-SWCNT films also provide a promising platform for the development of biosensing devices.展开更多
In this paper, electromagnetic poly（3,4-ethylenedioxythiophene）/γ-Fe2O3 （PEDOT/γ-Fe2O3 ） micro-bowls, 1-2 gm in diameter, were prepared by a simple environment-friendly process. In this method, the aqueous solu...In this paper, electromagnetic poly（3,4-ethylenedioxythiophene）/γ-Fe2O3 （PEDOT/γ-Fe2O3 ） micro-bowls, 1-2 gm in diameter, were prepared by a simple environment-friendly process. In this method, the aqueous solution of cetyltrimethylammonium bromide （CTAB） instead of any organic solvent was used. FeC13 acted as a source of FeIII for the formation of γ-Fe2O3 and as an oxidant for the polymerization of 3,4-ethylenedioxythiophene （EDOT）. The bowl-shaped morphology of PEDOT/γ-Fe2O3 composites was strongly influenced by the concentration of CTAB, FeCl2, ammonia solution and the reaction temperature. The saturation magnetization of PEDOT/γ-Fe2O3 micro-bowls increased with the increase of FeC12 concentration and reached 6.20 AmE/kg at the FeCl2 concentration of 0.30 mol/L. The conductivity of the PEDOT/γ-Fe2O3 composites was in the range of 101 S/cm. The electrical and magnetic sources of PEDOT/γ-Fe2O3 micro-bowls were confirmed by SEM-EDX, TEM, XRD and XPS spectra. And the possible formation mechanism of PEDOT//7：Fe203 was proposed.展开更多
In this study, a simple and effective method was proposed to improve the electrocatalytic ability of overoxidized poly(3,4-ethylenedioxythiophene)-overoxidized polypyrrole composite films modified on glassy carbon ele...In this study, a simple and effective method was proposed to improve the electrocatalytic ability of overoxidized poly(3,4-ethylenedioxythiophene)-overoxidized polypyrrole composite films modified on glassy carbon electrode for rutin and luteolin determination. The composite electrode was prepared by cyclic voltammetry copolymerization with LiClO_(4)-water as the supporting electrolyte. The peak current of rutin and luteolin on the composite electrode gradually decreased or even disappeared with the increase in the positive potential limit. After incubation in NaOH–ethanol solution with a volume ratio of 1:1, the composite electrodes prepared at positive potential limit greater than 1.5 V exhibited enhanced differential pulse voltammetry peak currents, reduced charge transfer resistance, larger effective specific surface area and higher electron transfer rate constant. The composite electrode prepared in the potential range of 0–1.7 V showed optimal electrocatalytic performance. The X-ray photoelectron spectroscopy results indicated that the content of –SO_(2)/–SO and –C=N– groups in the composite film increased significantly after incubation. Further, the Raman spectra and Fourier transform infrared spectra revealed that the thiophene ring structure changed from benzene-type to quinone-type, and the quinone-type pyrrole ring was formed. The electrocatalytic mechanism of the composite film was proposed based on the experimental results and further verified by Density Functional Theory calculation.展开更多
A multi-technique approach to prove the preparation of poly(3,4-ethylenedioxythiophene/cucurbit[7]uril)pseudorotaxanes(PEDOT∙CB7-PPs)is reported.Molecular docking simulation and matrix-assisted laser desorption/ioniza...A multi-technique approach to prove the preparation of poly(3,4-ethylenedioxythiophene/cucurbit[7]uril)pseudorotaxanes(PEDOT∙CB7-PPs)is reported.Molecular docking simulation and matrix-assisted laser desorption/ionization mass spectrometry(MALDI MS)validate the complexation ability of the CB7 molecule towards 3,4-ethylenedioxythiophene(EDOT),which leads to the EDOT∙CB7 inclusion complex.Oxidative polymerization of EDOT∙CB7 enabled the synthesis of PEDOT∙CB7-PPs.The water-soluble part of PEDOT∙CB7-PPs was selected,freeze-dried,and chemically characterized.Furthermore,dynamic light scattering(DLS)has been used to study the particle size and z-potential(ZP-ζ)of PEDOT∙CB7-PPs.The ZP-ζvalue(35 mV)evidenced that the PEDOT∙CB7-PPs formed stable water dispersion.By combining the emerging nanopore resistive pulse sensing technique(Np-RPS)and computational modeling,we identified strong interactions of PEDOT∙CB7-PPs with the aerolysin(Ael)nanopore.PEDOT∙CB7-PPs behave as positive charged species,and thus trans negative bias promotes its interactions with the Ael nanopore.The computational modeling results are fully consistent with the Np-RPS detection,which also reveals strong interactions between PEDOT∙CB7-PPs and the Ael nanopore.With this study,we hope to provide new insights and a better understanding of the interactions between supramolecular complexes based on CB7 and biological entities,which is instrumental for future applications in the field of nanobiotechnology.展开更多
Au nanoparticles(AuNPs)were prepared by reducing HAuCl4 with NaBH4,and then adsorbed uniformly on the surface of carboxylated nanocrystalline cellulose(CNCC).The obtained AuNPs/CNCC particles were doped into a conduct...Au nanoparticles(AuNPs)were prepared by reducing HAuCl4 with NaBH4,and then adsorbed uniformly on the surface of carboxylated nanocrystalline cellulose(CNCC).The obtained AuNPs/CNCC particles were doped into a conductive polymer of poly(3,4-ethylenedioxythiophene)(PEDOT)to yield a highly conductive nanocomposite,which was deposited onto a glassy carbon electrode(GCE)by an electrochemical method.The PEDOT/AuNPs/CNCC nanocomposite showed low electrochemical impedance and good electrocatalytic activity toward ascorbic acid.Based on this novel nanocomposite material,an amperometric sensor was developed for the detection of ascorbic acid with a detection limit as low as 0.29μM.When operated at-0.15 V,the sensor detected ascorbic acid in the range of 0.88μM to 15000μM.展开更多
Recently, increasing attention has been paid to magneto-conjugated polymer core-shell nanoparticles （NPs） as theranostic platforms. However, the utilization of surfactants and extra oxidizing agents with potential t...Recently, increasing attention has been paid to magneto-conjugated polymer core-shell nanoparticles （NPs） as theranostic platforms. However, the utilization of surfactants and extra oxidizing agents with potential toxicity in synthesis, the lack of general methods for the controlled synthesis of various kinds of magnetic NP （MNP）@conjugated polymer NPs, and the difficulty of obtaining balanced magneto-optical properties have greatly limited the applications of magneto-conjugated polymers in theranostics. We developed an in situ surface polymerization method free of extra surfactants and oxidizing agents to synthesize MNP@polypyrrole （PPy） NPs with balanced, prominent magneto-optical properties. MNP@PPy NPs with an adjustable size, different shapes, and a controlled shell thickness were obtained using this method. The method was extended to synthesize other MNP-conjugated polymer core-shell NPs, such as MNP@polyaniline and MNP@poly（3,4-ethylenedioxythiophene）：poly（4- styrenesulfonate） （PEDOT：PSS）. We discuss the formation mechanism of the proposed method according to our experimental results. Finally, using the optical and magnetic properties of the obtained MNP@PEDOT：PSS NPs, in vivo multimodal imaging-guided hyperthermia was induced in mice, achieving an excellent tumor-ablation therapeutic effect. Our work is beneficial for extending the application of MNP-conjugated polymer core-shell NPs in the biomedical field.展开更多
An increase of work function （0.3 eV） is achieved by irradiating poly（3,4-ethylenedioxythiophene）：poly（styrene sul- fonate） （PEDOT：PSS） film in vacuum with 254-nm ultraviolet （UV） light. The mechanism for ...An increase of work function （0.3 eV） is achieved by irradiating poly（3,4-ethylenedioxythiophene）：poly（styrene sul- fonate） （PEDOT：PSS） film in vacuum with 254-nm ultraviolet （UV） light. The mechanism for such an improvement is investigated by photoelectron yield spectroscopy, X-ray photo electron energy spectrum, and field emission technique. Sur- face oxidation and composition change are found as the reasons for work function increase. The UV-treated PEDOT：PSS film is used as the hole injection layer in a hole-only device. Hole injection is improved by UV-treated PEDOT：PSS film without baring the enlargement of film resistance. Our result demonstrates that UV treatment is more suitable for modifying the injection barrier than UV ozone exposure.展开更多
基金Financial supports from the Natural Science Foundation of Shaanxi Province,China(Grant No.:2020JM-652)Fundamental Research Funds for the Central Universities of Xi’an Jiaotong University(Grant No.:xzy012020054)Cultivation Project of Xi’an Health Committee(Grant No.:2020MS02)。
文摘An innovative,ternary nanocomposite composed of overoxidized poly(3,4-ethylenedioxythiophene)(OPEDOT),gold nanoparticles(Au NPs),and electrochemically reduced graphene oxide(ERGO)was prepared on a glassy carbon electrode(GCE)(OPEDOT-Au NPs-ERGO/GCE)through homogeneous chemical reactions and heterogeneous electrochemical methods.The morphology,composition,and structure of this nanocomposite were characterized by transmission electron microscopy,scanning electron microscopy,X-ray diffraction,and X-ray photoelectron spectroscopy.The electrochemical properties of the OPEDOT-Au NPs-ERGO/GCE were investigated by cyclic voltammetry using potassium ferricyanide and hexaammineruthenium(III)chloride redox probe systems.This modified electrode shows excellent electro-catalytic activity for dopamine(DA)and uric acid(UA)under physiological p H conditions,but inhibits the oxidation of ascorbic acid(AA).Linear voltammetric responses were obtained when DA concentrations of approximately 4.0-100μM and UA concentrations of approximately 20-100μM were used.The detection limits(S/N=3)for DA and UA were 1.0 and 5.0μM,respectively,under physiological conditions and in the presence of 1.0 m M of AA.This developed method was applied to the simultaneous detection of DA and UA in human urine,where satisfactory recoveries from 96.7%to 105.0%were observed.This work demonstrates that the developed OPEDOT-Au NPs-ERGO ternary nanocomposite,with its excellent ion-selectivity and electro-catalytic activity,is a promising candidate for the simultaneous detection of DA and UA in the presence of AA in physiological and pathological studies.
基金Funded by National Natural Science Foundation of China(Nos.11179015,51173108)Innovation Program of Shanghai Municipal Education Commission(No.12ZZ143)
文摘Poly （3, 4-ethylenedioxythiophene） （PEDOT）, together with its dopes, such as poly （styrene sulfonate） （PSS）, has been acknowledged to have a wide range of biomedical applications as an important conducting polymer. In this study, gelatin can be polymerized into PEDOT/PSS polymers on indium tin oxide （ITO）-coated glass. PEDOT/PSS/gelatin layer on ITO-coated glass significantly decreases electrochemical impedance spectroscopy （EIS） and increases charge delivery capacity relative to the gelatin layer and bare ITO- coated glass, comparable to the PEDOT/PSS layer on ITO-coated glass. PEDOT/PSS/gelatin layer on ITO- coated glass enhances pheochromocytoma （PC 12） cell affinity, possesses a high biocompatibility and promotes PC 12 cell growth by delivery of electrical stimulation. These results suggest that gelatin can be incorporated into the PEDOT/PSS polymers through electrochemical polymerization and the PEDOT/PSS/gelatin layer on ITO-coated glass possesses high electrochemical and biological activities.
基金Natural Science Foundation of Guangxi Province(2017GXNSFAA198274)
文摘[Objective] This paper was to introduce the chemical oxidative synthesis process, properties and test methods of 3,4-ethylenedioxythiophene(EDOT). [Method] The poor water solubility of EDOT was solved by using polyethylene glycol 20000(PEG) as the surfactant. The monomer was polymerized by chemical oxidative synthesis. The product was analyzed and verified by infrared spectrum, X-ray diffraction, ultraviolet-visible absorption spectra.[Result] The conductivity of the product was the best when the mass ratio of PEG and EDOT was 1∶1. The effects of oxidant dose and reaction time on the conductivity and yield of the product showed certain regularity. [Conclusion] EDOT could be polymerized by PEG and FeCl3, and the polymerization product was PEDOT.
基金supported by the National Natural Science Foundation of China(51972234,51632010)the National Key Research&Development Project of China(Grant No.2018YFE0111500)。
文摘In this work,poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)(PEDOT:PSS)coated silver telluride(PCeAg2Te)nanorods were prepared by a wet-chemical method using the PEDOT:PSS coated tellurium(PCeTe)nanorods as the templates.Flexible PCeAg2Te nanocomposite film on polyethersulfone(PES)substrate was prepared through vacuum filtration followed by mechanical pressing process.An optimal PCeAg2Te nanocomposite film showed a maximum power factor of 143.3 mW/mK^(2) at room temperature and 221.7 μW/mK^(2 ) at 373 K.The electrical conductivity of the PCeAg2Te composite film decreased by3.3%after bending for 1000 times around a rod with a radius of 5 mm.An eight-leg thermoelectric generator assembled with the optimal PCeAg2Te nanocomposite film generated a maximum output power and output density of 209.4 nW and 141.5 mW/cm^(2) at a temperature gradient of 30.3 K.This work provides a facile method to prepare thermoelectric materials for flexible thermoelectric generators.
基金financially supported by NSFC(Nos.50963002,51073074)Key Projects in the National Science & Technology Pillar Program in the Eleventh Five-year Plan Period(Nos.2006BAD02A04,2006BAD01A01)+3 种基金Jiangxi Provincial Department of Science and Technology(No.2006BAD01A01-2-5)Jiangxi Provincial Department of Education (Nos.GJJ11590,GJJ10678)Natural Science Foundation of Jiangxi Province(No.2010GZH0041)Key Laboratory of Photochemical Conversion and Optoelectronic Materials,TIPC,CAS,and Jiangxi Provincial Innovation Fund of Postgraduates(No.YC10A063)
文摘Vitamin C （VC） content in commercial juices was voltammetrically determined using a highly selective and sensitive poly（3,4-ethylenedioxythiophene methanol）/ascorbate oxidase/Nafion-single-walled carbon nanotubes （PEDOTM/AO/Nation-SWCNT） biosensor. The biocompatible PEDOTM matrix was prepared facilely by the one-step electrochemical deposition technique in lithium perehlorate aqueous solutions. AO was dip-coated on the surface of the biocompatible PEDOTM matrix. The mixture of Nafion-SWCNT was dip-cast onto the surface of AO layer when it was obtained by blending Nation solution and SWCNT dispersion together in a volume ratio of 1：1. The prepared PEDOTM/AO/Nafion-SWCNT biosensor was used for the voltammetric determination of VC, which exhibited the good linear range （4.0 ~ 10-s-3 x 10-s mol/L）, low detection limit （13 I^mol/L）, pronounced sensitivity （1.4072 mA （mmol/L） i cm 2）, high bioaftinity （low apparent Michaelis-Menten constant）, good stability （good repeatability）, high specificity （good anti-interference ability） coupled with the good reliability and feasibility （the determination of VC in commercial juices）. Meanwhile, the good aqueous solubility and the low onset oxidation potential of EDOTM will be more beneficial to the application in biosensor field compared to 3,4-ethylenedioxythiophene. Moreover, the good biocompatibility of PEDOTM matrix and high selectivity of Nation-SWCNT films also provide a promising platform for the development of biosensing devices.
基金financially supported by the National Natural Science Foundation of China (No.50973098)National Science and Technology Support Program (No.2012BAB15B02)the New Zealand Foundation for Science and Technology (contract No.UOAX0806)
文摘In this paper, electromagnetic poly（3,4-ethylenedioxythiophene）/γ-Fe2O3 （PEDOT/γ-Fe2O3 ） micro-bowls, 1-2 gm in diameter, were prepared by a simple environment-friendly process. In this method, the aqueous solution of cetyltrimethylammonium bromide （CTAB） instead of any organic solvent was used. FeC13 acted as a source of FeIII for the formation of γ-Fe2O3 and as an oxidant for the polymerization of 3,4-ethylenedioxythiophene （EDOT）. The bowl-shaped morphology of PEDOT/γ-Fe2O3 composites was strongly influenced by the concentration of CTAB, FeCl2, ammonia solution and the reaction temperature. The saturation magnetization of PEDOT/γ-Fe2O3 micro-bowls increased with the increase of FeC12 concentration and reached 6.20 AmE/kg at the FeCl2 concentration of 0.30 mol/L. The conductivity of the PEDOT/γ-Fe2O3 composites was in the range of 101 S/cm. The electrical and magnetic sources of PEDOT/γ-Fe2O3 micro-bowls were confirmed by SEM-EDX, TEM, XRD and XPS spectra. And the possible formation mechanism of PEDOT//7：Fe203 was proposed.
基金support of the Key Research and Development(R&D)Projects of Shanxi Province(Grant No.201903D121114)supported by Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi(Grant No.2020L0667).
文摘In this study, a simple and effective method was proposed to improve the electrocatalytic ability of overoxidized poly(3,4-ethylenedioxythiophene)-overoxidized polypyrrole composite films modified on glassy carbon electrode for rutin and luteolin determination. The composite electrode was prepared by cyclic voltammetry copolymerization with LiClO_(4)-water as the supporting electrolyte. The peak current of rutin and luteolin on the composite electrode gradually decreased or even disappeared with the increase in the positive potential limit. After incubation in NaOH–ethanol solution with a volume ratio of 1:1, the composite electrodes prepared at positive potential limit greater than 1.5 V exhibited enhanced differential pulse voltammetry peak currents, reduced charge transfer resistance, larger effective specific surface area and higher electron transfer rate constant. The composite electrode prepared in the potential range of 0–1.7 V showed optimal electrocatalytic performance. The X-ray photoelectron spectroscopy results indicated that the content of –SO_(2)/–SO and –C=N– groups in the composite film increased significantly after incubation. Further, the Raman spectra and Fourier transform infrared spectra revealed that the thiophene ring structure changed from benzene-type to quinone-type, and the quinone-type pyrrole ring was formed. The electrocatalytic mechanism of the composite film was proposed based on the experimental results and further verified by Density Functional Theory calculation.
基金supported by a grant of the Ministry of Research,Innovation and Digitization,CNCS–UEFISCDI,project number PN-III-P4-PCE-2021-0906within PNCDI III and the Institute desÉtudes Avancées(IEA)of Cergy-Pontoise University(Project INEX“Pi-ROT”#73).
文摘A multi-technique approach to prove the preparation of poly(3,4-ethylenedioxythiophene/cucurbit[7]uril)pseudorotaxanes(PEDOT∙CB7-PPs)is reported.Molecular docking simulation and matrix-assisted laser desorption/ionization mass spectrometry(MALDI MS)validate the complexation ability of the CB7 molecule towards 3,4-ethylenedioxythiophene(EDOT),which leads to the EDOT∙CB7 inclusion complex.Oxidative polymerization of EDOT∙CB7 enabled the synthesis of PEDOT∙CB7-PPs.The water-soluble part of PEDOT∙CB7-PPs was selected,freeze-dried,and chemically characterized.Furthermore,dynamic light scattering(DLS)has been used to study the particle size and z-potential(ZP-ζ)of PEDOT∙CB7-PPs.The ZP-ζvalue(35 mV)evidenced that the PEDOT∙CB7-PPs formed stable water dispersion.By combining the emerging nanopore resistive pulse sensing technique(Np-RPS)and computational modeling,we identified strong interactions of PEDOT∙CB7-PPs with the aerolysin(Ael)nanopore.PEDOT∙CB7-PPs behave as positive charged species,and thus trans negative bias promotes its interactions with the Ael nanopore.The computational modeling results are fully consistent with the Np-RPS detection,which also reveals strong interactions between PEDOT∙CB7-PPs and the Ael nanopore.With this study,we hope to provide new insights and a better understanding of the interactions between supramolecular complexes based on CB7 and biological entities,which is instrumental for future applications in the field of nanobiotechnology.
基金supported by the National Natural Science Foundation of China(21422504 and 21275087)the Natural Science Foundation of Shandong Province of China(JQ201406).
文摘Au nanoparticles(AuNPs)were prepared by reducing HAuCl4 with NaBH4,and then adsorbed uniformly on the surface of carboxylated nanocrystalline cellulose(CNCC).The obtained AuNPs/CNCC particles were doped into a conductive polymer of poly(3,4-ethylenedioxythiophene)(PEDOT)to yield a highly conductive nanocomposite,which was deposited onto a glassy carbon electrode(GCE)by an electrochemical method.The PEDOT/AuNPs/CNCC nanocomposite showed low electrochemical impedance and good electrocatalytic activity toward ascorbic acid.Based on this novel nanocomposite material,an amperometric sensor was developed for the detection of ascorbic acid with a detection limit as low as 0.29μM.When operated at-0.15 V,the sensor detected ascorbic acid in the range of 0.88μM to 15000μM.
文摘Recently, increasing attention has been paid to magneto-conjugated polymer core-shell nanoparticles （NPs） as theranostic platforms. However, the utilization of surfactants and extra oxidizing agents with potential toxicity in synthesis, the lack of general methods for the controlled synthesis of various kinds of magnetic NP （MNP）@conjugated polymer NPs, and the difficulty of obtaining balanced magneto-optical properties have greatly limited the applications of magneto-conjugated polymers in theranostics. We developed an in situ surface polymerization method free of extra surfactants and oxidizing agents to synthesize MNP@polypyrrole （PPy） NPs with balanced, prominent magneto-optical properties. MNP@PPy NPs with an adjustable size, different shapes, and a controlled shell thickness were obtained using this method. The method was extended to synthesize other MNP-conjugated polymer core-shell NPs, such as MNP@polyaniline and MNP@poly（3,4-ethylenedioxythiophene）：poly（4- styrenesulfonate） （PEDOT：PSS）. We discuss the formation mechanism of the proposed method according to our experimental results. Finally, using the optical and magnetic properties of the obtained MNP@PEDOT：PSS NPs, in vivo multimodal imaging-guided hyperthermia was induced in mice, achieving an excellent tumor-ablation therapeutic effect. Our work is beneficial for extending the application of MNP-conjugated polymer core-shell NPs in the biomedical field.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.61076057,61376059,61171023,and 91221202,)the National Basic Research Program of China(Grant Nos.2012CB932701 and 2011CB933001)
文摘An increase of work function （0.3 eV） is achieved by irradiating poly（3,4-ethylenedioxythiophene）：poly（styrene sul- fonate） （PEDOT：PSS） film in vacuum with 254-nm ultraviolet （UV） light. The mechanism for such an improvement is investigated by photoelectron yield spectroscopy, X-ray photo electron energy spectrum, and field emission technique. Sur- face oxidation and composition change are found as the reasons for work function increase. The UV-treated PEDOT：PSS film is used as the hole injection layer in a hole-only device. Hole injection is improved by UV-treated PEDOT：PSS film without baring the enlargement of film resistance. Our result demonstrates that UV treatment is more suitable for modifying the injection barrier than UV ozone exposure.
