A new tdterpenoid glycoside, 3-β-O-β-D-glucopyranosyl presenegenin 28-O-α-L-arabipyranosyl（1 → 3）-6-β- xylopyranosyl（1 → 4）-[β-D-apiofuranosyl（1 → 3）]-Ct-L-rhamnopyranosyl（1 → 2）-[α-L-rhamnopyranosyl...A new tdterpenoid glycoside, 3-β-O-β-D-glucopyranosyl presenegenin 28-O-α-L-arabipyranosyl（1 → 3）-6-β- xylopyranosyl（1 → 4）-[β-D-apiofuranosyl（1 → 3）]-Ct-L-rhamnopyranosyl（1 → 2）-[α-L-rhamnopyranosyl（1 → 3）]-β-D-fucopyranosyl ester （1） was isolated from the Polygala tenuifolia Willd., together with two known saponins, including polygalasaponinXXIV （2） and polygalasaponinXXVIII （3）. The structure of new compound was elucidated by spectroscopic methods.展开更多
Two new dioxyxanthones, polyhongkongenoxanthones A and B（1 and 2） were isolated from the herbs of Polygala hongkongensis, together with six known xanthones. Their structures were elucidated on the basis of chemical ...Two new dioxyxanthones, polyhongkongenoxanthones A and B（1 and 2） were isolated from the herbs of Polygala hongkongensis, together with six known xanthones. Their structures were elucidated on the basis of chemical and spectroscopic evidence. The isolates were tested for their cytotoxicity against three tumor cell lines（HepG2, GLC-82 and MCF-7, HepG2=human hepatocellular carcinoma cells; GLC-82=human lung carcinoma cells; MCF-7= human breast carcinoma cells） by MTT assay, among which polyhongkongenoxanthone B（2）, 1,7-dihydroxy-2,3- methylenedioxyxanthone（3） and 1,7-dihydroxy-3,4,8-trimethoxyxanthone（6） are potential antitumor candidate due to their significant cytotoxic effects on the three cell lines..展开更多
Two new megastigmane glycosides,7Z-roseoside,and 7Z-trifostigmanoside Ⅰ,as well as,four known compounds,trifostigmanoside Ⅱ,epimedin C,3＇,7-dihydroxy-4＇-methoxyisoflavone-7-D-glucopyranoside,and formenonetin,were ...Two new megastigmane glycosides,7Z-roseoside,and 7Z-trifostigmanoside Ⅰ,as well as,four known compounds,trifostigmanoside Ⅱ,epimedin C,3＇,7-dihydroxy-4＇-methoxyisoflavone-7-D-glucopyranoside,and formenonetin,were isolated from Polygala hongkongensis Hemsl.The structures of the isolated compounds were established on the basis of UV,IR,NMR,and MS spectral data.Megastigmane glycosides（1-3）were isolated from the family Polygalaceae for the first time.展开更多
Introduction Xanthones are secondary metabolites commonly occurring in a few higher plant families, fungi and lichen. Their high taxonomic value in such families and their pharmacological properties, including in vitr...Introduction Xanthones are secondary metabolites commonly occurring in a few higher plant families, fungi and lichen. Their high taxonomic value in such families and their pharmacological properties, including in vitro cytotoxicity, in vivo antitumour activity, antifungal, antibacterial, antiinflammatory properties and aldose reductase inhibitory activity have provoked great interest. The discovery of the antidiabetic activity of some axnthones＇ from Swertiaceae has prompted us to undertake a more broadly search for novel xanthones from plants of Polygalaceae. The phytochemical investigation has not been performed on this plant up to now. Herein we report the isolation and structure elucidation of two new xanthones （ compounds 1 and 2 ） and three known xanthones （compound 3, 4 and 5 ）.展开更多
基金the National Nature Science Foundation of China (No.30772890)the Collaborative Education,Research and Development Project of Beijing Municipal Commission of Education and the Key Project of Chinese Ministry of Education (No.108132).
文摘A new tdterpenoid glycoside, 3-β-O-β-D-glucopyranosyl presenegenin 28-O-α-L-arabipyranosyl（1 → 3）-6-β- xylopyranosyl（1 → 4）-[β-D-apiofuranosyl（1 → 3）]-Ct-L-rhamnopyranosyl（1 → 2）-[α-L-rhamnopyranosyl（1 → 3）]-β-D-fucopyranosyl ester （1） was isolated from the Polygala tenuifolia Willd., together with two known saponins, including polygalasaponinXXIV （2） and polygalasaponinXXVIII （3）. The structure of new compound was elucidated by spectroscopic methods.
基金Supported by the Natural Science Foundation of Guangdong Province, China(No.9151064201000042)
文摘Two new dioxyxanthones, polyhongkongenoxanthones A and B（1 and 2） were isolated from the herbs of Polygala hongkongensis, together with six known xanthones. Their structures were elucidated on the basis of chemical and spectroscopic evidence. The isolates were tested for their cytotoxicity against three tumor cell lines（HepG2, GLC-82 and MCF-7, HepG2=human hepatocellular carcinoma cells; GLC-82=human lung carcinoma cells; MCF-7= human breast carcinoma cells） by MTT assay, among which polyhongkongenoxanthone B（2）, 1,7-dihydroxy-2,3- methylenedioxyxanthone（3） and 1,7-dihydroxy-3,4,8-trimethoxyxanthone（6） are potential antitumor candidate due to their significant cytotoxic effects on the three cell lines..
文摘Two new megastigmane glycosides,7Z-roseoside,and 7Z-trifostigmanoside Ⅰ,as well as,four known compounds,trifostigmanoside Ⅱ,epimedin C,3＇,7-dihydroxy-4＇-methoxyisoflavone-7-D-glucopyranoside,and formenonetin,were isolated from Polygala hongkongensis Hemsl.The structures of the isolated compounds were established on the basis of UV,IR,NMR,and MS spectral data.Megastigmane glycosides（1-3）were isolated from the family Polygalaceae for the first time.
文摘Introduction Xanthones are secondary metabolites commonly occurring in a few higher plant families, fungi and lichen. Their high taxonomic value in such families and their pharmacological properties, including in vitro cytotoxicity, in vivo antitumour activity, antifungal, antibacterial, antiinflammatory properties and aldose reductase inhibitory activity have provoked great interest. The discovery of the antidiabetic activity of some axnthones＇ from Swertiaceae has prompted us to undertake a more broadly search for novel xanthones from plants of Polygalaceae. The phytochemical investigation has not been performed on this plant up to now. Herein we report the isolation and structure elucidation of two new xanthones （ compounds 1 and 2 ） and three known xanthones （compound 3, 4 and 5 ）.
